Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Trends Microbiol. 2022 Jul 14:S0966-842X(22)00143-3. doi: 10.1016/j.tim.2022.06.001. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO as an important public health concern, with emerging serotypes showing resistance to multiple antibiotics. Indeed, although the introduction of pneumococcal conjugate vaccines (PCVs) has been associated with an overall decline in pneumococcal AMR, there have been increases in prevalence of potentially disease-causing AMR serotypes not targete...
Source: Trends in Microbiology - July 17, 2022 Category: Microbiology Authors: Eleanor Rose Watkins Akuzike Kalizang'Oma Andrea Gori Sunetra Gupta Robert S Heyderman Source Type: research
Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Trends Microbiol. 2022 Jul 14:S0966-842X(22)00143-3. doi: 10.1016/j.tim.2022.06.001. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO as an important public health concern, with emerging serotypes showing resistance to multiple antibiotics. Indeed, although the introduction of pneumococcal conjugate vaccines (PCVs) has been associated with an overall decline in pneumococcal AMR, there have been increases in prevalence of potentially disease-causing AMR serotypes not targete...
Source: Trends in Microbiology - July 17, 2022 Category: Microbiology Authors: Eleanor Rose Watkins Akuzike Kalizang'Oma Andrea Gori Sunetra Gupta Robert S Heyderman Source Type: research
Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Trends Microbiol. 2022 Jul 14:S0966-842X(22)00143-3. doi: 10.1016/j.tim.2022.06.001. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO as an important public health concern, with emerging serotypes showing resistance to multiple antibiotics. Indeed, although the introduction of pneumococcal conjugate vaccines (PCVs) has been associated with an overall decline in pneumococcal AMR, there have been increases in prevalence of potentially disease-causing AMR serotypes not targete...
Source: Trends in Microbiology - July 17, 2022 Category: Microbiology Authors: Eleanor Rose Watkins Akuzike Kalizang'Oma Andrea Gori Sunetra Gupta Robert S Heyderman Source Type: research
Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Trends Microbiol. 2022 Jul 14:S0966-842X(22)00143-3. doi: 10.1016/j.tim.2022.06.001. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO as an important public health concern, with emerging serotypes showing resistance to multiple antibiotics. Indeed, although the introduction of pneumococcal conjugate vaccines (PCVs) has been associated with an overall decline in pneumococcal AMR, there have been increases in prevalence of potentially disease-causing AMR serotypes not targete...
Source: Trends in Microbiology - July 17, 2022 Category: Microbiology Authors: Eleanor Rose Watkins Akuzike Kalizang'Oma Andrea Gori Sunetra Gupta Robert S Heyderman Source Type: research
Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction
Trends Microbiol. 2022 Jul 14:S0966-842X(22)00143-3. doi: 10.1016/j.tim.2022.06.001. Online ahead of print.ABSTRACTStreptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO as an important public health concern, with emerging serotypes showing resistance to multiple antibiotics. Indeed, although the introduction of pneumococcal conjugate vaccines (PCVs) has been associated with an overall decline in pneumococcal AMR, there have been increases in prevalence of potentially disease-causing AMR serotypes not targete...
Source: Trends in Microbiology - July 17, 2022 Category: Microbiology Authors: Eleanor Rose Watkins Akuzike Kalizang'Oma Andrea Gori Sunetra Gupta Robert S Heyderman Source Type: research
Promising Role of Emodin as Therapeutics to Against Viral Infections
Front Pharmacol. 2022 May 4;13:902626. doi: 10.3389/fphar.2022.902626. eCollection 2022.ABSTRACTEmodin is an anthraquinone derivative that is widely present in natural plants and has a wide spectrum of pharmacological effects, such as antibacterial, anti-inflammatory, anti-fibrotic and anticancer and so on. Through reviewing studies on antiviral effect of emodin in the past decades, we found that emodin exhibits ability of inhibiting the infection and replication of more than 10 viruses in vitro and in vivo, including herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), human cytomegalovirus (HCMV), Epstein-Barr virus (...
Source: Herpes - May 23, 2022 Category: Infectious Diseases Authors: Qingqing Shao Tong Liu Wenjia Wang Tianli Liu Ximing Jin Zhuo Chen Source Type: research
Bendamustine treatment of haematological malignancies: significant risks of opportunistic viral, fungal and bacterial infections
CONCLUSION: Our observations showed that even with a vigorous anti-infective strategy, bendamustine treatment was still associated with significant risks of bacterial and opportunistic viral and fungal infections.PMID:35544671 | DOI:10.1080/16078454.2022.2072065 (Source: Hematology)
Source: Hematology - May 11, 2022 Category: Hematology Authors: Tony K Y Wu Karen H K Tang Yu-Yan Hwang Thomas S Y Chan Eric Tse Yok-Lam Kwong Source Type: research
Promising Role of Emodin as Therapeutics to Against Viral Infections
Emodin is an anthraquinone derivative that is widely present in natural plants and has a wide spectrum of pharmacological effects, such as antibacterial, anti-inflammatory, anti-fibrotic and anticancer and so on. Through reviewing studies on antiviral effect of emodin in the past decades, we found that emodin exhibits ability of inhibiting the infection and replication of more than 10 viruses in vitro and in vivo, including herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), human cytomegalovirus (HCMV), Epstein-Barr virus (EBV), coxsackievirus B (CVB), hepatitis B virus (HBV), influenza A virus (IAV), SARS-CoV, viral ...
Source: Frontiers in Pharmacology - May 4, 2022 Category: Drugs & Pharmacology Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
