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Specialty: Genetics & Stem Cells

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Total 914 results found since Jan 2013.

Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training for Cognitive Function and Activities of Daily Living in Patients with Post-Stroke Cognitive Impairment: A Systematic Review and Meta-Analysis
CONCLUSIONS: The pooled data showed more positive effects of rTMS + cognitive training for global cognition, executive function, working memory and ADL in patients with PSCI. While, robust evidence of rTMS + cognitive training for global cognition, executive function, working memory and ADL from the Grade recommendations is lacking. Further, rTMS + cognitive training did not show no better effects on memory. Future definitive trials are needed to determine the benefits of rTMS + cognitive training for cognitive function and ADL in the field of PSCI.PMID:37004840 | DOI:10.1016/j.arr.2023.101919
Source: Ageing Research Reviews - April 2, 2023 Category: Genetics & Stem Cells Authors: Yong Gao Yue Qiu Qingyan Yang Shaowen Tang Jianqiu Gong Hong Fan Yuefeng Wu Xiao Lu Source Type: research

GSE232936 Gene expression profiles of endothelium, microglia and oligodendrocytes in hippocampus of post-stroke depression rat at single cell resolution
This study characterized the single cell expression profile of hippocampal PSD, and unmask the differential expressed genes of endothelium, microglia and oligodendrocytes, emphasizing the crosstalk among them to provide theoretical basis for the in-depth mechanism research and drug therapy of PSD.
Source: GEO: Gene Expression Omnibus - May 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Rattus norvegicus Source Type: research

Integrated analysis of circRNA-associated ceRNA in ischemic stroke
In conclusion, we identified hsa_circ_0011474-hsa-miR-20a-5p/hsa-miR-17-5p-CDKN1A as a significant ceRNA axis. Our findings provide new insights into the pathogenesis of IS and offer promising diagnostic and predictive biomarkers.
Source: Frontiers in Genetics - May 30, 2023 Category: Genetics & Stem Cells Source Type: research

GSE225948 Brain and blood single-cell transcriptomic analysis in acute and subacute phases after experimental stroke
Contributors : Lidia Garcia-Bonilla ; Gianfranco Racchumi ; Josef AnratherSeries Type : Expression profiling by high throughput sequencingOrganism :The secondary immune response to ischemic stroke progresses for days to weeks and involves glial and brain endothelium activation, recruitment of peripheral immune cells, and release of cytokines and chemokines. Whereas there is evidence that the acute inflammatory response contributes to the progression of ischemic brain injury, on the other hand, recent research points at a more multifaceted role of immune cells in brain ischemia, where immune cells participate in repair proc...
Source: GEO: Gene Expression Omnibus - June 14, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Source Type: research

GSE210986 Single-Cell  Analysis Uncovers Dramatic Alteration of Microglia Heterogeneity after Ischemic Stroke
Contributors : Yueman Zhang ; Yunlu Guo ; Tingting HuangSeries Type : Expression profiling by high throughput sequencingOrganism :Microglia are resident myeloid cells in the central nervous system (CNS) that regulate homeostasis and protect CNS from damage and infection. The phenotype of microglia is critical in regulating the propagation and resolution of inflammatory responses after ischemic stroke. However, little is known of its complexity and heterogeneity in the above context. Here, using single-cell RNA sequencing (scRNA-seq) of over 11,000 cells from the mice ischemic brain tissues, we demonstrated a previously und...
Source: GEO: Gene Expression Omnibus - June 14, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Source Type: research

Intravascular cell therapy in stroke patients: where the cells go and what they do.
PMID: 23477388 [PubMed - in process]
Source: Regenerative Medicine - March 1, 2013 Category: Genetics & Stem Cells Authors: Korhonen M, Jolkkonen J Tags: Regen Med Source Type: research

A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case–control study
A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case–control study European Journal of Human Genetics advance online publication, October 8 2014. doi:10.1038/ejhg.2014.212 Authors: Cristiano Fava, Marketa Sjögren, Sandra Olsson, Håkan Lövkvist, Katarina Jood, Gunnar Engström, Bo Hedblad, Bo Norrving, Christina Jern, Arne Lindgren & Olle Melander
Source: European Journal of Human Genetics - October 8, 2014 Category: Genetics & Stem Cells Authors: Cristiano FavaMarketa SjögrenSandra OlssonHåkan LövkvistKatarina JoodGunnar EngströmBo HedbladBo NorrvingChristina JernArne LindgrenOlle Melander Source Type: research

New | phs000615.v1.p1 | NINDS Stroke Genetics Network (SiGN)
NINDS Stroke Genetics Network (SiGN)   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - September 29, 2014 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

New | phs000691.v1.p1 | CIP: Differential Response to Hydroxyurea and Incidence of Stroke in Sickle Cell Disease
CIP: Differential Response to Hydroxyurea and Incidence of Stroke in Sickle Cell Disease   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - July 10, 2014 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

New | phs000343.v3.p1 | The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - June 11, 2013 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

New | phs000343.v2.p1 | The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial
The Genomics and Randomized Trials Network (GARNET) Vitamin Intervention Stroke Prevention (VISP) trial   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - October 5, 2012 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

Update | phs000292.v1.p1 | Genotype imputed data added | GENEVA Genetics of Early Onset Stroke (GEOS) Study
GENEVA Genetics of Early Onset Stroke (GEOS) Study   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - April 26, 2012 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

New | phs000343.v1.p1 | Vitamin Intervention for Stroke Prevention (VISP)
Vitamin Intervention for Stroke Prevention (VISP)   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - May 2, 2011 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

Update | phs000292.v1.p1 | Two genotype files updated, multiple genotype files added | GENEVA Genetics of Early Onset Stroke (GEOS) Study
GENEVA Genetics of Early Onset Stroke (GEOS) Study   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - February 17, 2011 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

New | phs000292.v1.p1 | GENEVA Genetics of Early Onset Stroke (GEOS) Study
GENEVA Genetics of Early Onset Stroke (GEOS) Study   ( study page | release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - August 6, 2010 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research