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Procedure: SPECT

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Total 384 results found since Jan 2013.

White Matter Perivascular Spaces on Magnetic Resonance Imaging: Marker of Cerebrovascular Amyloid Burden? Brief Reports
Conclusions— This pilot study suggests a possible association between cerebrovascular amyloid deposition and CSO-PVS, with potential pathophysiological implications.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Charidimou, A., Hong, Y. T., Jager, H. R., Fox, Z., Aigbirhio, F. I., Fryer, T. D., Menon, D. K., Warburton, E. A., Werring, D. J., Baron, J.-C. Tags: PET and SPECT, Intracerebral Hemorrhage Brief Reports Source Type: research

Refractory status epilepticus due to SMART syndrome
Conclusions Taking into account clinical evolution and ictal neuroimaging studies, status epilepticus could explain the origin of these episodes in SMART syndrome. Although most patients have reversible symptoms, in some cases, aggressive treatment to avoid sequelae is needed. This article is part of a Special Issue entitled “Status Epilepticus”.
Source: Epilepsy and Behavior - June 12, 2015 Category: Neurology Source Type: research

Refractory status epilepticus due to SMART syndrome.
CONCLUSIONS: Taking into account clinical evolution and ictal neuroimaging studies, status epilepticus could explain the origin of these episodes in SMART syndrome. Although most patients have reversible symptoms, in some cases, aggressive treatment to avoid sequelae is needed. This article is part of a Special Issue entitled "Status Epilepticus". PMID: 26071996 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 11, 2015 Category: Neurology Authors: Jaraba S, Puig O, Miró J, Velasco R, Castañer S, Rodríguez L, Izquierdo C, Simó M, Veciana M, Falip M Tags: Epilepsy Behav Source Type: research

Regional Cerebral Blood Flow Single Photon Emission Computed Tomography for detection of Frontotemporal dementia in people with suspected dementia.
CONCLUSIONS: At present, we would not recommend the routine use of rCBF SPECT in clinical practice because there is insufficient evidence from the available literature to support this.Further research into the use of rCBF SPECT for differentiating FTD from other dementias is required. In particular, protocols should be standardised, study populations should be well described, the threshold for 'abnormal' scans predefined and clear details given on how scans are analysed. More prospective cohort studies that verify the presence or absence of FTD during a period of follow up should be undertaken. PMID: 26102272 [PubMed ...
Source: Cochrane Database of Systematic Reviews - June 23, 2015 Category: Journals (General) Authors: Archer HA, Smailagic N, John C, Holmes RB, Takwoingi Y, Coulthard EJ, Cullum S Tags: Cochrane Database Syst Rev Source Type: research

Incremental Prognostic Value of Brachial-Ankle Pulse Wave Velocity to Single-Photon Emission Computed Tomography in Patients with Suspected Coronary Artery Disease.
CONCLUSIONS: baPWV has an incremental prognostic value to traditional risk factors and MPI. Therefore, baPWV can be used to identify subjects at higher risk of cardiovascular events in patients undergoing SPECT. PMID: 26235347 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - August 4, 2015 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Pathological Laughing: Brain SPECT Findings
We present the case of a 40-year-old man consulting for uncontrollable episodes of laughing related to emotional lability and not systematically linked to feelings of happiness. Seven months earlier he had presented a pontine ischemic stroke related to an occlusion of the basilar and left vertebral arteries. No epileptic activity or new MRI brain lesions were found. Brain perfusion SPECT performed showed marked hypoperfusion in the right frontal inferior and temporoinsular regions, suggesting a diaschisis phenomenon caused by pontine lesions and highlighted laughing regulation pathways. The patient was successfully treated...
Source: Clinical Nuclear Medicine - August 11, 2015 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Development of obsessive compulsive disorder (ocd) secondary to traumatic brain injury-review of literature and comparison with sample of patients from lishman unit, maudsley hospital
Conclusion The main focus of organic OCD seems to be from disruption to the OFC and basal ganglia but other areas have been implicated as has been reflected in the literature as well as the patients on the Lishman brain injury unit, Maudsley Hospital.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 13, 2015 Category: Neurosurgery Authors: Guillochon, R., Dilley, M. Tags: Genetics, Drugs: CNS (not psychiatric), Epilepsy and seizures, Movement disorders (other than Parkinsons), Neurological injury, Parkinson's disease, Stroke, Trauma CNS / PNS, Anxiety disorders (including OCD and PTSD), Radiology, Radiology (diagnostics), Source Type: research

Increase in 18F-Fluoroacetate Uptake in Patients With Chronic Hemodynamic Cerebral Ischemia Brief Reports
Conclusions— In patients with atherosclerotic internal carotid artery or middle cerebral artery disease, 18F-FACE uptake is increased in the noninfarcted cerebral cortex with chronic hemodynamic ischemia characterized by misery perfusion with decreased oxygen metabolism. Increased 18F-FACE uptake may indicate the cortical regions that are at particular risk for ischemic damage.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Yamauchi, H., Kagawa, S., Kishibe, Y., Takahashi, M., Nishii, R., Mizuma, H., Takahashi, K., Onoe, H., Higashi, T. Tags: PET and SPECT Brief Reports Source Type: research

Arterial Spin Labeling Perfusion Magnetic Resonance Image with Dual Postlabeling Delay: A Correlative Study with Acetazolamide Loading I-Iodoamphetamine Single-Photon Emission Computed Tomography
Perfusion magnetic resonance image with arterial spin labeling (ASL) provides a completely noninvasive measurement of cerebral blood flow (CBF). However, arterial transient times can have a marked effect on the ASL signal. For example, a single postlabeling delay (PLD) of 1.5 seconds underestimates the slowly streaming collateral pathways that maintain the cerebrovascular reserve (CVR). To overcome this limitation, we developed a dual PLD method.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2015 Category: Neurology Authors: Sei Haga, Takato Morioka, Takafumi Shimogawa, Tomoaki Akiyama, Kei Murao, Yuka Kanazawa, Tetsuro Sayama, Shuji Arakawa Source Type: research

Imaging Inflammation in Cerebrovascular Disease Topical Reviews
Source: Stroke - September 28, 2015 Category: Neurology Authors: Gounis, M. J., van der Marel, K., Marosfoi, M., Mazzanti, M. L., Clarencon, F., Chueh, J.-Y., Puri, A. S., Bogdanov, A. A. Tags: Cardiovascular imaging agents/Techniques, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT, Other imaging Topical Reviews Source Type: research

Hemodynamic Significance of Internal Carotid or Middle Cerebral Artery Stenosis Detected on Magnetic Resonance Angiography.
CONCLUSION: A considerable proportion of ICA-MCA stenosis detected on MRA does not cause CVR impairment despite a fair correlation between them. Thus, hemodynamic state needs to be assessed for evaluating significance of stenosis, particularly in asymptomatic patients. PMID: 26446655 [PubMed - in process]
Source: Yonsei Medical Journal - October 9, 2015 Category: Universities & Medical Training Authors: Seo HJ, Pagsisihan JR, Paeng JC, Choi SH, Cheon GJ, Chung JK, Lee DS, Kang KW Tags: Yonsei Med J Source Type: research

Apraxic agraphia following thalamic damage: Three new cases.
Abstract Apraxic agraphia (AA) is a so-called peripheral writing disorder following disruption of the skilled movement plans of writing while the central processes that subserve spelling are intact. It has been observed in a variety of etiologically heterogeneous neurological disorders typically associated with lesions located in the language dominant parietal and frontal region. The condition is characterized by a hesitant, incomplete, imprecise or even illegible graphomotor output. Letter formation cannot be attributed to sensorimotor, extrapyramidal or cerebellar dysfunction affecting the writing limb. Detailed...
Source: Brain and Language - October 10, 2015 Category: Neurology Authors: Vandenborre D, van Dun K, Engelborghs S, Mariën P Tags: Brain Lang Source Type: research

SPECT Perfusion Imaging Demonstrates Improvement of Traumatic Brain Injury With Transcranial Near-infrared Laser Phototherapy.
Authors: Henderson TA, Morries LD Abstract Traumatic brain injury (TBI) is a growing health concern affecting civilians and military personnel. Near-infrared (NIR) light has shown benefits in animal models and human trials for stroke and in animal models for TBI. Diodes emitting low-level NIR often have lacked therapeutic efficacy, perhaps failing to deliver sufficient radiant energy to the necessary depth. In this case report, a patient with moderate TBI documented in anatomical magnetic resonance imaging (MRI) and perfusion single-photon emission computed tomography (SPECT) received 20 NIR treatments in the cours...
Source: Advances in Mind Body Medicine - November 7, 2015 Category: Psychiatry Tags: Adv Mind Body Med Source Type: research

Translocator protein and new targets for neuroinflammation
Abstract The mitochondrial translocator protein (18 kDa; TSPO) is involved in a wide array of physiological processes importantly including cholesterol transport, steroidogenesis and immunomodulation. In the central nervous system (CNS), TSPO expression regionally increases in glial cells upon brain insult with a differential pattern suggestive of cell-specific functions in inflammation and repair. These properties have made TSPO a valuable marker to assess the state, and progression of diverse neurological and psychiatric conditions, including traumatic brain injury, stroke, neurodegenerative diseases, anxiety, ...
Source: Clinical and Translational Imaging - November 16, 2015 Category: Radiology Source Type: research

Near infrared spectroscopy - investigations in neurovascular diseases.
This study showed increased LFOs amplitude only in FHM patients with co-existing common type of migraine, but not in patients with pure FHM phenotype. This suggests that the sensitivity to NO resides within the common migraine phenotypes rather than the FHM phenotype. Stimulation of the sphenopalatine ganglion (SPG) may lead to parasympathetic outflow and cause pain in cluster headache (CH). The fifth study therefore investigated pain and autonomic symptoms in relation to high or low SPG frequency stimulation in chronic CH patients. Cortical changes in oxygenated hemoglobin (HbO) were also recorded with NIRS and showed a m...
Source: Danish Medical Journal - December 12, 2015 Category: Journals (General) Tags: Dan Med J Source Type: research