Characteristics of patients with COVID-19 pneumonia at Hvidovre Hospital, March-April 2020.
CONCLUSIONS: The manifestations of COVID-19 at presentation were similar to those seen in other reports. Our population was older, slightly overrepresented by women and had a high level of co-morbidity. COVID-19 admittance was associated with frequent need of intensive care and mechanical ventilation that was associated with a very high mortality. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32448405 [PubMed - indexed for MEDLINE] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 27, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Initial experiences from patients with COVID-19 on ventilatory support in Denmark.
CONCLUSIONS: COVID-19 patients have characteristic reproducible laboratory findings and present a major challenge due to their illness severity and required treatment length. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32351196 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

COVID-19 is possibly a consequence of the anthropogenic biodiversity crisis and climate changes.
Authors: Lorentzen HF, Benfield T, Stisen S, Rahbek C PMID: 32351197 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Trends of ankyloglossia and lingual frenotomy in hospital settings among children in Denmark.
CONCLUSIONS: Ankyloglossia and frenotomy increased significantly during the period 1996-2015 among children in Denmark according to nationwide hospital data. Rates of both ankyloglossia and frenotomy were highest in children less than one year of age and among boys. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32351198 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

An analysis of the productivity and impact of clinical PhD theses from the University of Copenhagen.
CONCLUSIONS: The scientific outcome of clinical PhD theses was high as 92% of all manuscripts were published with a field-weighted journal ranking and citation impact above the world average, indicating that the productivity and quality of the clinical PhD theses are not compromised even though strategic motives is a driver for graduation. FUNDING: This study was funded by theGraduate School of the Faculty of Health and Medical Sciences, University of Copenhagen. TRIAL REGISTRATION: not relevant. PMID: 32351199 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Danish translation and linguistic validation of the BREAST-Q.
CONCLUSIONS: The BREAST-Q can now be used for patients undergoing breast surgery in Denmark to measure change in quality of life and patient satisfaction as part of the outcome assessment. The BREAST-Q may be used for both individual and group measurements in clinical and research settings alike. Data collection with BREAST-Q can provide valuable information for use in clinical counseling of women undergoing breast surgery. A psychometric validation of the Danish version of the BREAST-Q is currently underway. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32351200 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

High incidence of chronic hypoparathyroidism secondary to total thyroidectomy.
CONCLUSIONS: The incidence of chronic HypoPT after TT is higher than previously reported. This is primarily due to a lack of consistency in the definition and follow-up time between studies. Younger patients and those with a toxic indication for surgery are at higher risk of HypoPT after TT than other patients. FUNDING: none. TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency (REG-015-2019) and The Ethical Committee of Central Denmark (No. 66792). PMID: 32351201 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Adherence to guidelines on red blood cell transfusions in women having post-partum haemorrhage.
CONCLUSIONS: The majority of RBC-Ts for obstetric patients were conducted in line with the guidelines. However, 6.0% of RBC-Ts were registered to be in discrepancy with the guidelines and 20.3% of RBC-Ts were prescribed on the "low Hb" criterium solely. It is possible, though, that the 20.3% is overestimated due to insufficient descriptions of indications for RBC-T in patient files. FUNDING: none. TRIAL REGISTRATION: The study was approved by the management at Rigshospitalet. PMID: 32351202 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Management of chronic obstructive pulmonary disease in general practice in Denmark.
This study was sponsored by Boehringer Ingelheim, Denmark, and the authors have all received payment for their contribution to the study. TRIAL REGISTRATION: The trial was approved by the Danish Health Authority and the Danish Data Protection Agency. PMID: 32351203 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 1, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Dilemmas and Priorities in the Neonatal Intensive Care Unit during the COVID-19 Pandemic.
Authors: Breindahl M, Zachariassen G, Christensen PS, Hinriksen TB PMID: 32314729 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 23, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Variations in open and laparoscopic repair of paediatric inguinal hernia.
CONCLUSIONS: This study found considerable variation in the execution of both open and laparoscopic repair of inguinal hernias in children of different age groups. Research into inguinal hernia repair in children is needed to rationalise and update guidelines in order to improve quality and facilitate research. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32285794 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Urine samples produced at patients' own home rarely meet recommendations for analysis.
CONCLUSION: The findings of this study suggest that urine samples produced at patients' own home on suspicion of urinary tract infection rarely meet recommendations required for further diagnostic analysis. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32285795 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Characteristics in a traumatic spinal cord injury population.
CONCLUSIONS: In a Danish population of patients with traumatic SCI, we observed a preponderance for surgical treatment among a) younger patients, b) patients with vertebral fractures, and c) more severe SCI cases. FUNDING: This study received no external funding. TRIAL REGISTRATION: The study was conducted in accordance with the Helsinki II Declaration. Data were obtained with permission from the Danish Data Protection Agency (record number 2012-41-0572). PMID: 32285796 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Anaesthetic technique and outcomes after colorectal cancer surgery.
CONCLUSION: Anaesthetic technique might influence time to discharge and bowel function in an ERAS setting. FUNDING: none TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency (record number 2008-58-0020). Under Danish law, consent from participants is not required in observational studies. PMID: 32285797 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Medical students' perspectives on the ethics of clinical reality.
CONCLUSIONS: Students' perspectives on ethical dilemmas in the clinical setting provide a unique opportunity to integrate a variety of ethical dimensions into bioethical education and draw attention to overlooked everyday ethical dilemmas. Thus, involving the students' perspectives may be a way to bridge the gap between bioethical theory and the ethics of clinical reality. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32285798 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Correction to: Foetal sex determination at the second trimester anomaly scan in Denmark.
Authors: Størup G, Sørensen AN, Dalsgaard A, Grønkj R M Abstract This corrects the article pii: A5580. PMID: 32285799 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - April 16, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Distribution of risk alleles in patients with age-related macular degeneration.
CONCLUSIONS: Our results support the notion that ARMS2 and CFH are central in neovascular AMD and GA, and that the risk allele for rs1061170 in CFH is associated with accelerated onset of bilateral neovascular AMD. FUNDING: The Velux Foundation, the Danish Eye Research Foundation, Fight for Sight Denmark, the University of Copenhagen, and Region Zealand funded this study. None of the funding bodies had any role in the design, execution or interpretation of the research performed. TRIAL REGISTRATION: not relevant. PMID: 32138827 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Stoma-site hernia after stoma reversal following rectal cancer resection.
CONCLUSIONS: 25% developed reversal-site incisional hernia. We were unable to find any predictors for development of stoma reversal-site hernia. If hernias occur as frequently as this study shows, investigation of potential ways to decrease their occurrence is warranted. FUNDING: none. TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency (R. no. 2012-58-0004). PMID: 32138828 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Outcomes and follow-up programmes in extreme preterm children in Denmark in the EPICE/SHIPS cohort.
CONCLUSIONS: Few severe difficulties, e.g., cerebral palsy, were found. At five years, parental reporting on fine motor skills was associated with fine and overall motor skills as assessed by professionals. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32138829 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Translation and linguistic validation of the Bronchiectasis Health Questionnaire (BHQ) into Danish.
CONCLUSIONS: The BHQ is translated and validated in Danish and retains good validity properties. This questionnaire is ready for use in daily clinical practice among Danish-speaking patients. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32138830 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Trauma team training at a "high-risk, low-incidence" hospital.
CONCLUSIONS: Despite limitations in this study, our results point towards a reduced process time after the implementation of TTT. At an organisational level, TTT can draw attention to challenges, inappropriate local procedures and allocation of material and staff in order to improve trauma resuscitations. Only 12% of patients had an ISS> 15, emphasising the need to simulate trauma resuscitations using TTT. FUNDING: none. TRIAL REGISTRATION: The study was registered with the Danish Data Protection Agency. PMID: 32138831 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Risk of pancreatitis in patients with inflammatory bowel disease - a meta-analysis.
CONCLUSIONS: The risk of acute pancreatitis is increased in patients with IBD and higher for patients with CD. Due to the observational design of the studies included in our meta-analysis, the mechanisms underlying the increased risk of pancreatitis are unknown and remain to be investigated. Studies of the risk of chronic pancreatitis among patients with IBD are warranted. FUNDING: This work was supported by a grant from the Novo Nordisk Foundation (NNF16OC0022586). The funder had no role in the study design, collection, analysis, interpretation of the data, or the writing of the manuscript. TRIAL REGISTRATION: not...
Source: Danish Medical Journal - March 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

A Disclosure Form for Work Submitted to Medical Journals – A Proposal From the International Committee of Medical Journal Editors.
A Disclosure Form for Work Submitted to Medical Journals – A Proposal From the International Committee of Medical Journal Editors. Dan Med J. 2020 Feb;67(2): Authors: Taichman DB, Backus J, Baethge C, Bauchner H, Flanagin A, Florenzano F, Frizelle FA, Godlee F, Gollogly L, Haileamlak A, Hong ST, Horton R, James A, Laine C, Miller PW, Pinborg A, Rubin EJ, Sahni P PMID: 32053482 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Regional and socio-economic variation in survival after a pancreatic cancer diagnosis in Denmark.
CONCLUSIONS: We found significant differences in overall survival across the five Danish regions following a diagnosis of pancreatic cancer. The regional variation in survival was largely attributable to differences in the propensity to use surgical resection. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32053483 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

The Danish version of the Western Ontario Rotator Cuff Index.
CONCLUSIONS: The D-WORC is a valid, reliable and responsive questionnaire that can be used in Danish populations. FUNDING: Lone Dragnes Brix: Familien Hede Nielsens Fond, Gurli og Hans Engell Friis' Fond, Aase og Ejnar Danielsens Fond, Knud og Edith Eriksons Mindefond, Region Midtjyllands Sundhedsvidenskabelige Forskningsfond. TRIAL REGISTRATION: Danish Data Protection Agency: 1-16-02-653-15. PMID: 32053484 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Urine dipstick for predicting intrapartum recto-vaginal colonisation by group B streptococci.
CONCLUSION: Dipstick urine analysis had a low sensitivity for predicting intrapartum recto-vaginal colonisation with GBS. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32053485 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Use and utility of serologic tests for rheumatoid arthritis in primary care.
CONCLUSIONS: ACPA has a higher PPV for RA than IgM RF, whereas their NPV is identical. ACPA is the better choice when testing for RA in primary care. Seroconversion is rare, and it is only rarely relevant to retest. FUNDING: The Department of Clinical immunology at Odense University Hospital funded the study. TRIAL REGISTRATION: not relevant. PMID: 32053486 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Completeness in the recording of vital signs in ambulances increases over time.
CONCLUSIONS: The completeness of registration increased gradually but decreased slightly after implementation of the new version. A high completeness combined with few implausible outliers and concordance indicate correctness of the vital sign registrations. FUNDING: none. TRIAL REGISTRATION: Approval for the use of data was given by the medical director of the Emergency Medical Services, the North Denmark Region. PMID: 32053487 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Cumulative radiation exposure during current scoliosis management.
CONCLUSIONS: Cumulative radiation dose during scoliosis treatment varies substantially depending on radiographic follow-up protocol, intraoperative and ancillary imaging. By using low-dose X-ray systems in combination with a low-dose protocol for intraoperative navigation, it is possible to keep exposure to patients at a minimum while still providing optimal care. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32053488 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 14, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

The effects of preoperative point-of-care focused cardiac ultrasound in high-risk patients: study protocol for a prospective randomised controlled trial.
CONCLUSIONS: The knowledge generated from this study may facilitate changes in the anaesthesia evaluation and decision process and, consequently, in the entire perioperative anaesthesia clinical practice. The study has the potential to reduce the risk of perioperative cardiopulmonary complications which directly implies improved patient outcome and reduced hospital costs. FUNDING: The Research Fund of the Department of Anaesthesiology, Randers Regional Hospital, The Central Denmark Region's Medical Research Fund and the Hospital of Southern Jutland. TRIAL REGISTRATION: NCT03501927. PMID: 31908251 [PubMed - in p...
Source: Danish Medical Journal - January 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Evaluation of a sentence test in noise in children with hearing impairment.
CONCLUSIONS: Our study produced knowledge about a new generation of children with HI, who showed potentials not previously described. Future research on cognitive development of paediatric populations with HI is essential, as knowledge from adult populations cannot be transferred directly to paediatric populations. FUNDING: The project received funding from the Innovation Foundation, the Oticon Foundation, Decibel and The Capital Region of Denmark. TRIAL REGISTRATION: not relevant. PMID: 31908252 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - January 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Treatment and outcomes of a Danish ovarian cancer population.
CONCLUSIONS: Ovarian cancer remains a highly aggressive disease with most patients diagnosed in advanced stages. Treatment has not changed much in the past 15 years and the same is evident for the overall survival. FUNDING: Tobias Berg received an unrestricted research grant from the Danish Cancer Society. TRIAL REGISTRATION: not relevant. PMID: 31908253 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - January 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

A randomised controlled trial of lidocaine infusion on post-operative opioid consumption in patients undergoing robotic colorectal surgery.
CONCLUSIONS: In this randomised, double-blinded, prospective study using intravenous lidocaine versus 0.9% saline in robot-assisted colorectal surgery, we found no significant difference in post-operative cumulated morphine consumption at 24 or at 72 h. FUNDING: The study received funding from DASAIMs Forskningsinitiativ (2016) and DASAIMs Smerteforskningspris (2016). TRIAL REGISTRATION: The trial is registered with EudraCT (2014-003466-25) and ClinicalTrials.gov (ID: NCT03044808). PMID: 31908254 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - January 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Danish expanded newborn screening is a successful preventive public health programme.
CONCLUSIONS: This update of eNBS in Denmark confirms that eNBS is a successful preventive public health programme. Early treatment in a latent phase of disease is effective and screening should be extended to other diseases not currently in the programme. FUNDING: The work was supported by grants from The Ronald McDonald Børnefond, Danmarks Sundhedsfond, Direktør Ib Henriksens Fond, Ragnhild Ibsens Legat til Medicinsk Forskning, Gerda og Aage Haenschs Fond, Dronning Louises Børnehospitals Forskningsfond, Læge Sofus Carl Emil Friis og Hustru Olga Doris Friis's Legat, Aase and Ejnar Danielsens ...
Source: Danish Medical Journal - January 8, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Foetal sex determination at the second trimester anomaly scan in Denmark.
Authors: Størup G, Sørensen AN, Dalsgaard A, Grønkjær M Abstract INTRODUCTION: For decades, ultrasound has enabled determination of foetal sex. Foetal sex is medically indicated in sex-linked diseases, syndromes and multiple pregnancy, but genital malformations are rare. However, guidelines on standard views seem sparse and foetal sex determination is not considered mandatory. The aim of this study was to provide an initial overview on the practice of foetal sex determination in Denmark and the accuracy of the examinations at the second trimester anomaly scan at a regional and a universit...
Source: Danish Medical Journal - December 5, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Analgesics use and withdrawal in people with dementia - a register-based Danish study and a systematic review.
CONCLUSIONS: In Denmark, use of opioids is higher in elderly with dementia compared to elderly without dementia. The evidence suggests that withdrawal of analgesics may aggravate pain but increases in pain scores may be of little clinical relevance in most people. Clinical trials investigating analgesics withdrawal are warranted. PMID: 31791478 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 5, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

A population-based study of patients in Danish hospitals who are in their last year of life.
CONCLUSIONS: More than one in five inpatients in Danish hospitals are imminently dying or in their last year of life. Knowledge of the patients' uneven distribution in the hospital system can underpin organisational strategies to focus on end-of-life care provision. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31791479 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 5, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Everolimus as adjunctive treatment in tuberous sclerosis complex-associated epilepsy in children.
CONCLUSIONS: Early data on everolimus as an adjunctive treatment in TSC-associated epilepsy are promising with regards to both effect and tolerability. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31791480 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 5, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Improved survival of very preterm born infants from 2000 to 2013 in Denmark.
Authors: Løgavlen VV, Mikkelsen MS, Zachariassen G Abstract INTRODUCTION: Survival has improved among very preterm born infants, but improved treatment strategies might be associated with increasing rates of neonatal morbidity. The aim of this study was to assess survival and major morbidities among very and extremely preterm born infants treated in a Danish neonatal intensive care unit. METHODS: This was an observational cohort study including very preterm infants (gestational age (GA)
Source: Danish Medical Journal - December 5, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Implementation of pulse oximetry screening in a Danish maternity ward.
CONCLUSIONS: Early POS as part of the routine examination few hours postpartum seemed natural to midwives and parents but induced an increased false-positive rate. Early POS may discover other serious conditions in time for intervention. FUNDING: none. TRIAL REGISTRATION: none. PMID: 31686645 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 8, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Differential effects of text message reminders on non-attendance and late cancellations in a paediatric outpatient clinic.
Authors: Wolthers OD Abstract INTRODUCTION: SMS text appointment reminders reduce non-attendance rates in outpatient paediatric settings. The potential effect on late cancellation rates, however, has not been assessed. The aim of the present study was to assess if SMS text messaging reminders affect non-attendance and late cancellation rates in a secondary paediatric outpatient centre. METHODS: Non-attendances and late cancellations in children and adolescents aged 0-19 years of age were recorded prospectively during a year before and after the introduction of automatic SMS text messaging reminders. In a teleph...
Source: Danish Medical Journal - November 8, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Prevalence of clinical familial hypercholesterolaemia among patients with high cholesterol levels.
CONCLUSIONS: Clinical FH was common among patients with LDL-C concentration ≥ 5.0 mmol/l referred to a Danish lipid clinic. However, the concordance between the DLCN and the Simon Broome criteria was low in a specialised clinical setting. FUNDING: The study was supported by a SANOFI grant. TRIAL REGISTRATION: not relevant. PMID: 31686647 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 8, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Protocol for a randomised clinical trial of transoral ultrasound versus standard of care in the diagnosis of peritonsillar abscess.
CONCLUSIONS: This study will explore the clinical benefits of adding transoral ultrasound to the diagnostic work-up of patients with peritonsillar infections. FUNDING: The Rigshospitalet and Odense University Hospital Foundation. TRIAL REGISTRATION: Clinicaltrials NCT03824288. PMID: 31686648 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 8, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Regional and socioeconomic variation in survival of melanoma patients in Denmark.
CONCLUSIONS: The two regions with the lowest mortality (highest survival) had high absolute incidence rates of stage IA and thin melanomas, indicating a high level of diagnostic activity in these regions. There was no regional variation in the incidence of advanced melanoma. The optimal level of diagnostic investigation of skin lesions has yet to be established. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31686649 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 8, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Treatment of osteoarthritis with autologous and microfragmented adipose tissue.
CONCLUSIONS: The intra-articular injection of autologous, microfragmented adipose tissue for treatment of knee OA seems safe. Randomised controlled trials are needed to elucidate the efficacy of the treatment. TRIAL REGISTRATION: This study was registered in ClinicalTrials.gov (NCT02697682). FUNDING: none. PMID: 31571571 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - October 3, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

The use of allergen-specific IgE tests in general practice.
CONCLUSIONS: This is the first descriptive analysis of the use of testing for sIgE in general practice. Results from this study may be used to optimise how GPs order and interpret sIgE tests in the future. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31571572 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - October 3, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Efficacy of methotrexate in management of peripheral psoriatic arthritis - a systematic review.
CONCLUSIONS: Clinical benefits have been found in the treatment of PsA with MTX. MTX has demonstrated clinical efficacy in the treatment of psoriasis; however, the treatment of peripheral arthritis still lacks supportive evidence. More controlled trials need to be conducted to underpin evidence-based use of MTX. PMID: 31571573 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - October 3, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Validation study of the population included in the Danish Schizophrenia Registry.
CONCLUSIONS: The DSR includes the intended patient population and represents a valid and valuable source for improving quality of care and for research. FUNDING: The study was financed by the Danish Regional Development Fund for Clinical Quality. TRIAL REGISTRATION: not relevant. PMID: 31571574 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - October 3, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Parent satisfaction and symptom relief in children with otitis media undergoing tympanostomy tube insertion.
CONCLUSIONS: We report a consistent, high rate of symptom relief 1-12 months following TT insertion in children
Source: Danish Medical Journal - September 10, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Specialists' adherence to guidelines on tympanostomy tube insertion.
CONCLUSIONS: Using solely ePRO data, we found that Danish practicing ENT specialists adhere to the 2015 NCG in regard to OM symptom duration and RAOM. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31495368 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - September 10, 2019 Category: General Medicine Tags: Dan Med J Source Type: research