Use of antiepileptic drugs in women of fertile age.
CONCLUSIONS: The overall use of AEDs in women of fertile age and pregnant women has increased in the past 16 years, especially due to an increased use of lamotrigine. However, valproate use in pregnant women and in younger women of fertile age has become less frequent. FUNDING: This study received funding from the Lundbeck Foundation, the Danish Epilepsy Association, the Central Denmark Region and the Novo Nordisk Foundation (NNF16OC0019126). TRIAL REGISTRATION: none. PMID: 31315793 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Knee pain and associated complications after intramedullary nailing of tibial shaft fracture.
CONCLUSIONS: With a follow-up time of more than six years after receiving an IMN, patients in this study experienced more knee-specific symptoms, pain, limitations in sports and daily living than a reference population who had not undergone surgery. The study population also reported poorer quality of life outcomes than the reference population. FUNDING: none. TRIAL REGISTRATION: Approved by the Danish Data Protection Agency. Clinical trials: NCT03649360. PMID: 31315794 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Sepsis-related Organ Failure Assessment Score is a strong predictor of survival in acute-on-chronic liver failure.
CONCLUSIONS: The mortality was high in these severely ill patients, even when they received optimum supportive therapy in the ICU. The finding that the SOFA score and age best predicted mortality shows that the increased mortality was caused mainly by insufficiency of organs other than the liver. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31315795 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Language barriers and use of interpreters in two Danish paediatric emergency units.
CONCLUSIONS: Language barriers frequently affected communication and clinical decision-making in the two Danish paediatric emergency units studied. Even so, professional interpretation was not used. Further studies are needed to explore whether language is a barrier to equal health. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31315796 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Short-term outcomes after minimally invasive oesophagectomy.
This study reports the results of the first patients operated using this technique at our department. METHODS: All procedures were prospectively registered in a database. Patients were followed until death, two years after surgery or 1 January 2019. RESULTS: A total of 150 procedures were performed (from 23 November 2015 to 27 February 2018). The median proced-ure time decreased from 350 minutes for the initial 75 pa-tients to 320 minutes for the final 75 patients (p
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Combined endoscopic laparoscopic surgical treatment of advanced adenomas and early colon cancer.
CONCLUSIONS: CELS is a feasible treatment for colonic neoplasia where endoscopic resection alone is not technically possible. In case of severe co-morbidity ruling out segmental resection in patients diagnosed with T1 or T2 colorectal cancer, CELS treatment may be considered. FUNDING: none. TRIAL REGISTRATION: This study was assessed by The National Committee on Health Research Ethics (SJ-593), which concluded that the study required no approval from the Committee. The study was approved by the Danish Data Protection Agency (REG-126-2017). . PMID: 31315798 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Congenital heart defects in offspring of women with Type 2 diabetes - a systematic review.
CONCLUSIONS: The risk of congenital heart defects among offspring of women with Type 2 diabetes was comparable to that of offspring of women with Type 1 diabetes and almost four times higher than in the background population. PMID: 31256772 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Danish norms for the Strengths and Difficulties Questionnaire.
CONCLUSION: We expect that the availability of Danish SDQ norms will further stimulate the use of the instrument. FUNDING: TrygFonden provided financial support for the development of Danish SDQ norms. TRIAL REGISTRATION: not relevant. PMID: 31256773 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Low admittance rate after ambulatory laparoscopic surgery.
CONCLUSION: In patients undergoing ambulatory laparoscopic surgery using a perioperative multimodal analgesic regimen, pain was the limiting factor for discharge in 1% of patients operated in an ambulatory set-up. FUNDING: none. TRIAL REGISTRATION: Danish Data Protection Agency: 2012-58-0004, Danish Health Authority: 3-3013-1435/1, Clinicaltrial.gov: NCT02782832. PMID: 31256774 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Completeness and data validity in the Danish Achilles tendon Database.
CONCLUSIONS: This study documented a satisfactory completeness of data on the non-operated patients registered in the DADB and an unsatisfactory completeness of data on operated patients. All investigated parameters were valid. These results suggest that data in the DADB on non-operated patients can contribute to research within the field. Due to a limited sample on operated patients, conclusions should be made with caution. The logistics concerning data collection among operated patients warrants optimisation. FUNDING: not relevant. TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency an...
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

No reduction in mortality after centralisation in treatment of patients with ruptured abdominal aneurism.
CONCLUSIONS: In this population-based cohort study of patients surgically treated for rAAA, we found no consistent reduction in mortality over time following centralisation of treatment. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31256776 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Prevention of parastomal hernia using mesh in patients undergoing rectum extirpation.
CONCLUSIONS: This cohort study supports the thesis of a low short-time rate of parastomal hernia in patients who had a prophylactic mesh placed during the ostomy formation and indicates that the rate of hernia increases over time after the first post-operative year. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31256777 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Temporal trends in length of stay and readmissions after fast-track hip and knee arthroplasty.
CONCLUSIONS: A reduction in both LOS and proportion of patients with prolonged LOS without an increase in readmission is possible within a multicentre collaboration aiming at enhancing recovery and reducing morbidity. FUNDING: The study was supported by an unconditional PhD grant from Lundbeckfonden to PBP (R230-2017-166). TRIAL REGISTRATION: The study was registered with ClinicalTrials.gov (NCT01515670). PMID: 31256778 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Inflammatory response after transanal total mesorectal excision.
Authors: Alamili M, Levic K, Kanstrup K, Bisgaard T, Bulut O Abstract INTRODUCTION: The advantages of transanal total mesorectal excision (taTME) would be a reduction of the hernia rate and surgical trauma. The present study reports data for patients undergoing taTME and compares the post-operative immune response in taTME with those of conven-tional laparoscopic surgery (CLS) and single-port laparo-scopic surgery (SPLS). METHODS: A comparative cohort study in patients with rectal cancer undergoing taTME. C-reactive protein (CRP) and white blood cell count (WBC) were measured pre-operatively and on post-operati...
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

The day of week of elective colorectal cancer surgery has no impact on mortality and morbidity.
CONCLUSIONS: The day of week of operation could not be shown to have any significant impact on the risk of post-operative surgical or medical complications or on short-term mortality in patients undergoing elective surgery for colorectal cancer in Denmark. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31256780 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Pathology is common in subsequent visits after admission for non-specific abdominal pain.
Authors: Ravn-Christensen C, Qvist N, Bay-Nielsen M, Bisgaard T Abstract INTRODUCTION: Although not supported by evidence, there may be a risk of overlooking pathological findings at patients' return visit after emergency admission for non-specific abdominal pain (NSAP). The primary aim of this study was to evaluate the risk of missed acute pathology in patients primarily discharged with NSAP and re-admitted within three months. METHODS: This was a retrospective review of hospital records within a three-month period (1 September-30 November, 2014) in a university hospital with unrestricted referral of abdominal...
Source: Danish Medical Journal - July 2, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Venous thromboembolic complications following surgical treatment for degenerative spinal disease.
CONCLUSIONS: VTEs are an uncommon but potentially lethal complication in patients who undergo surgery for a degenerative spinal disease. Incidence and mortality were low in a consecutive cohort where rivaroxaban was used as thrombosis prophylaxis in patients with an increased preoperative risk of VTE. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31066352 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 9, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Hydrochloric acid prolongs the lifetime of central venous catheters in haematologic patients with bacteraemia.
CONCLUSIONS: The study's findings indicate that a prolonged use of CVC is possible following HCl instillation in adult haematologic patients with bacteraemia. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31066353 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 9, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Successful paediatric renography does not require sedation.
Authors: Kai CM, Ingvardsen B, Lemvig P, Sehested LT, Søndergaard LR, Møller S, Cortes D Abstract INTRODUCTION: Sedation is often used to optimise ren-ography in children
Source: Danish Medical Journal - May 9, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Subjective tiredness does not correlate with the Apnoea-Hypopnoea Index.
CONCLUSIONS: Monosymptomatic patient-reported tiredness should not raise suspicion of obstructive sleep apnoea. Conversely, if obstructive sleep apnoea is suspected, a lack of tiredness should not postpone further evaluation. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 31066355 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - May 9, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Long-term outcomes in patients after ligation of the intersphincteric fistula tract.
CONCLUSION: The present study shows that the LIFT procedure is a viable treatment option for transsphincteric fistulae. Furthermore, a second LIFT procedure is a plausible option for recurrent transsphincteric fistulae. In the case of recurrence, the fistula was frequently downgraded to a more benign intersphincteric variant. The study supports previous findings showing that long-term follow-up is required to successfully measure the outcome of LIFT surgery. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30910002 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 28, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Indwelling urinary catheterisation may increase risk of complications in hip and knee arthroplasty.
CONCLUSIONS: Routine use of perioperative indwelling urinary catheterisation in fast-track THA and TKA may increase the risk of post-operative UTI and does not eliminate the need for subsequent re-catheterisation. These findings speak against routine use of perioperative indwelling catheterisation. FUNDING: The study was supported by the Lundbeck Foundation and registered with clinicaltrials.gov. TRIAL REGISTRATION: clinicaltrials.gov 8 April 2014 (NCT02133768). PMID: 30910003 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 28, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Hypermobility among patients with greater trochanteric pain syndrome.
CONCLUSIONS: The prevalence of hypermobility in patients with GTPS was high, but the prevalence of hypermobility did not influence hip function and awareness. The results were based on a very low response rate and should be interpreted with this in mind. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30910004 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 28, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

No effect of human papillomavirus vaccination on sexual debut of school children.
Authors: Svarrer RO, Rasmussen AL, Lauszus FF, Hammer A Abstract INTRODUCTION: We aimed to describe sexual behaviour and knowledge about sexually transmitted infections (STI) among Danish adolescents stratified by gender and human papillomavirus (HPV) vaccination status. METHODS: We conducted a questionnaire study in Viborg Municipality, Denmark. A validated questionnaire was sent to all ninth-grade pupils without prior notice to either teachers or pupils. RESULTS: In 2014, 776 pupils attended the ninth grade, 685 (88%) of whom participated in the study. A total of 376 (55%) reported having received the HPV...
Source: Danish Medical Journal - March 28, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

A pilot cohort study of lumbar facet joint denervation in patients with chronic low-back pain.
CONCLUSIONS: This pilot cohort study found RF denervation of the facet joint to be a promising alternative for patients with chronic low-back pain. The effect persisted at the one-year follow-up; however, the effect diminished over time. FUNDING: The Danish Rheumatism Association, The A.P. Møller Foundation for the Advancement of Medical Science. TRIAL REGISTRATION: The study protocol was approved by the ethical committee of Southern Denmark with registration number S-20160070. PMID: 30864544 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 15, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Characteristics and outcomes in patients with primary intraspinal tumours.
CONCLUSIONS: The incidence of PIST seems to be higher in Western Denmark than in other European studies. PIST are rare in children. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30864545 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 15, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Auditory verbal skills training is a new approach in adult cochlear implant rehabilitation.
CONCLUSIONS: The AVST was successfully implemented at the CI Centre. Improvements in speech understanding and QoL were seen in both groups over time, but no differences were seen between the groups. The CI users in the intervention group received more fine-tuning of their processor. FUNDING: Oticon Medical A/S supported the study financially. TRIAL REGISTRATION: Not relevant as the study applied a prospective method study design. PMID: 30864546 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 15, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Evaluation of day-care tonsil surgery in young children.
CONCLUSIONS: Patients ≤ 4 years experienced significantly less haemorrhage but had more unplanned contacts than patients> 4 years. For reassurance of caretakers, easy access to telephone contact with hospital staff in the post-operative period is important. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30864547 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - March 15, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Clostridium histolyticum as first-line treatment of Dupuytren's disease.
CONCLUSIONS: Collagenase is a viable first-line treatment for MCP joint contractures. However, results are inferior in the PIP joint. FUNDING: This work was supported by the The Scientific Foundation of Horsens Regional Hospital (grant number 00.06-G01-1-17). TRIAL REGISTRATION: ClinicalTrials ID NCT03331926. PMID: 30722822 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

The clinical use of hyperbaric oxygen in the treatment of Danish patients with diabetic foot ulcers.
CONCLUSIONS: The study showed that Danish DFU patients who are offered HBOT are in advanced stages of their disease, and the referral hinges on local factors such as geography and the referring source rather than on standardised procedures. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30722823 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Barriers in pain treatment in the emergency and surgical department.
CONCLUSIONS: Time, staff education, interdisciplinary cooperation and patient involvement were the primary factors influencing pain treatment. Insufficient time and limited knowledge on the part of the healthcare providers were the greatest barriers preventing good pain treatment in everyday practice. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30722824 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Adherence to antibiotic guidelines in the treatment of acute pharyngeal infections.
CONCLUSIONS: A significant (37%) proportion of patients with acute pharyngeal infections were treated non-adherently to antibiotic guidelines, mainly because of (inappropriate) addition of metronidazole to penicillin. FUNDING: This work was supported by the Lundbeck Foundation (Grant number R185-2014-2482). TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency. PMID: 30722825 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Effect of hospital-admission volume on outcomes following acute non-variceal upper gastrointestinal bleeding.
CONCLUSIONS: A positive association between admission volumes of patients with NVUGIB and ReWHI was identified. No association between admission volumes and 30-day mortality or other failure of haemostasis events could be identified. FUNDING: none. TRIAL REGISTRATION: not applicable. PMID: 30722826 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

The effect of mental health on weight loss after bariatric surgery.
CONCLUSIONS: Eating disorder symptomology might explain the efficient weight loss results in the high-risk category. The high-risk category may have more mental health issues that are unrelated to obesity, which explains the proportionally reduced mental health improvement. The study calls for further research involving a larger study population and a longer follow-up period. FUNDING: The work was carried out as a part of the research programme Governing Obesity, funded by the University of Copenhagen Excellence Programme for Interdisciplinary Research. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02070081...
Source: Danish Medical Journal - February 7, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

A single administration of glucocorticoid increases exercise capacity in men with stable chronic obstructive pulmonary disease.
CONCLUSION: Our finding suggests that COPD patients experience improvements in exercise tolerance from a single high dose of glucocorticoid even in the stable phase of their disease. FUNDING: none. TRIAL REGISTRATION: EudraCT 2012-004503-13. PMID: 30573004 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 24, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

A nationwide cohort study of short- and long-term outcomes following emergency laparotomy.
CONCLUSIONS: More than one in every five patients died within one year after undergoing emergency laparotomy, and mortality rates were even higher when excluding minor laparotomies as almost one in every three patients died within one year. FUNDING: This study received support from the Frimodt-Heinecke Foundation and from the foundation Manufacturer Frands Køhler Nielsens and wife memorial fund. TRIAL REGISTRATION: The study was registered with Researchregistry.com (Id no: researchregistry2930). PMID: 30573005 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 24, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

A randomised clinical trial of take-home laparoscopic training.
Authors: Thinggaard E, Bjerrum F, Strandbygaard J, Konge L, Gögenur I Abstract INTRODUCTION: Simulation-based training in surgery helps trainees master laparoscopic skills, and training at home on mobile box trainers may allow trainees to reach proficiency faster. The aim of this study was to examine the added effects of training at home. METHODS: Participants were trainees from departments of surgery, gynaecology and urology who were recruited while taking part in a laparoscopic training course. The interven-tion consisted of added access to a mobile box trainer allowing participants to train at home. ...
Source: Danish Medical Journal - December 24, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Effects of strength training to patients undergoing dialysis: a systematic review.
CONCLUSIONS: The results suggest that it may be difficult to increase muscle mass with strength training in patients who are undergoing haemodialysis. Muscle growth may be impaired as a result of several catabolic conditions. Strength training was associated with important clinical outcomes including increased muscle strength and improved self-rated physical health and function. PMID: 30573007 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 24, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Usefulness of the STarT Back Screening Tool to predict pain problems after lumbar spine surgery.
CONCLUSIONS: The results of this study show that the STarT Back Screening Tool may be useful for identifying patients who are at a high risk of developing complex pain after spine surgery. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30511633 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Basic open surgical training course.
Authors: Christensen JB, Nodin E, Bach DZ, Fabrin A, Thingaard E Abstract INTRODUCTION: Fewer open surgical procedures are performed, and thus a need to learn open surgical techniques outside the operating room has emerged. Simulation training offers the possibility to train in a safe environment before operating on patients. The purpose of this study is to evaluate the effect of a simulation-based course in basic open surgical skills and to describe its pedagogical foundation, content and organisation. METHODS: Surgical trainees at the beginning of their surgical career participated in a basic open surgical sk...
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Use of preventive home visits by general practitioners in patients diagnosed with dementia.
CONCLUSIONS: GP's adherence to guidelines for patients identified with dementia leaves room for improvement as a significant part of the patients had not received the annual PHV as recommended in the guidelines. Furthermore, substantial variation between general practices indicates that not all GPs need to improve to the same extent. FUNDING: The study was supported by the Quality Improvement Committee for General Practice in the Region of Southern Denmark, Audit Project Odense and the University of Southern Denmark. TRIAL REGISTRATION: not relevant. PMID: 30511635 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Re-amputations and mortality after below-knee, through-knee and above-knee amputations.
CONCLUSIONS: The overall re-amputation rate ≤ 90 days following major lower-extremity amputation decreased significantly from 22% to 5% after cessation of the TKA procedures, but mortality remained unchanged. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30511636 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Refusal of pain medication is frequent in a Danish emergency department.
CONCLUSIONS: Pain was frequent, as it was seen in two thirds of non-critical adult patients in the ED. The majority of patients with pain had moderate to severe pain, but only one third of the patients with pain wanted pain-relieving treatment. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30511637 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Synchronous and metachronous liver metastases in patients with colorectal cancer.
CONCLUSIONS: The incidence of synchronous metastases has remained high despite improved diagnostic technology. Patient survival remains significantly lower when metastatic disease is present, even though treatment options for liver metastases have improved. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30511638 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - December 7, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Neurobiological effects of work-related stress: protocol for a case-control neuroimaging study.
CONCLUSIONS: This project is designed to generate entirely new and objective evidence of stress-induced cerebral illness, and to provide a basis for in-depth research and for a more rational management of this strenuous disorder. FUNDING: Private, industrial and public funds. TRIAL REGISTRATION: Clinicaltrails.gov/NCT03334045. PMID: 30382017 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Childhood trampoline injuries.
CONCLUSIONS: This study describes types of injuries and safety precautions related to trampoline use. 6% of all children in the ED had an injury related to trampoline use. 4% complied with all five recommended safety precautions. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30382018 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Type 1 narcolepsy is not present in 29 HPV-vaccinated individuals with subjective sleep complaints.
CONCLUSION: Our results do not suggest that an association exists between HPV vaccination and the development of narcolepsy type 1. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30382019 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Validation of the HeartDiet questionnaire.
CONCLUSIONS: HeartDiet is well aligned with results from a semi-quantitative FFQ and biomarkers, and it is a practical, easy and quick-to-use tool to describe and monitor if a diet is heart-healthy or not. FUNDING: The study was supported by the Danish Heart Association. TRIAL REGISTRATION: not relevant. PMID: 30382020 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Non-attendance in a secondary paediatric referral centre.
Authors: Wolthers OD Abstract INTRODUCTION: Non-attendance in outpatient clinics may be associated with risks to patients' health, disturb the management of clinics and cause a waste of healthcare resources. The aim of the present study was to measure the non-attendance rate in a secondary paediatric outpatient centre and to assess reasons for non-attendance. METHODS: Non-attendance in children and adolescents aged 0-19 years were recorded prospectively during a year. In a telephone interview, the families of non-attending patients were asked about their reasons for non-attending. RESULTS: The number of sch...
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research

Poor compliance with antimicrobial guidelines for childhood pneumonia.
CONCLUSIONS: Compliance with local guidelines was comparable to findings reported in similar single-centre studies. Airway aspiration may be a useful supplement to other investigations. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 30382022 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - November 2, 2018 Category: General Medicine Tags: Dan Med J Source Type: research