“Ictal epileptic headache” and the revised International Headache Classification (ICHD-3) published in Cephalalgia 2018, vol. 38(1) 1–211: Not just a matter of definition!
Publication date: Available online 14 August 2018Source: Epilepsy & BehaviorAuthor(s): Pasquale Parisi, Vincenzo Belcastro, Alberto Verrotti, Pasquale Striano, D.G.A. Kasteleijn-Nolst Trenitè (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 14, 2018 Category: Neurology Source Type: research

Executive and behavioral functioning in pediatric frontal lobe epilepsy
ConclusionRatings on the BRIEF, CBCL, and TRF are moderately to highly correlated, suggesting a (strong) link between executive and behavioral functioning. Subtle differences between parents and teachers ratings suggest different executive function demands in various settings. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 14, 2018 Category: Neurology Source Type: research

Negative effects of interictal spikes on theta rhythm in human temporal lobe epilepsy
Publication date: Available online 13 August 2018Source: Epilepsy & BehaviorAuthor(s): Xiaoxuan Fu, Youhua Wang, Manling Ge, Danhong Wang, Rongguang Gao, Long Wang, Jundan Guo, Hesheng LiuAbstractInterictal spike is a biomarker of epilepsy that can occur frequently between seizures. Its potential effects on brain oscillations, especially on theta rhythm (4–8 Hz) that is related to a variety of cognitive processes, remain controversial. Using local field potentials recorded from patients with temporal lobe epilepsy (TLE), we investigated here the impact of spikes on theta rhythm immediately after spikes and duri...
Source: Epilepsy and Behavior - August 13, 2018 Category: Neurology Source Type: research

Brain network alterations of mesial temporal lobe epilepsy with cognitive dysfunction following anterior temporal lobectomy
Publication date: Available online 13 August 2018Source: Epilepsy & BehaviorAuthor(s): Chao Zhang, Hongyu Yang, Chang Liu, Guojun Zhang, Nan Chen, Kuncheng LiAbstractThe aims of this study were to investigate the brain network connectivity alterations of intractable unilateral mesial temporal lobe epilepsy (MTLE) with cognitive dysfunction before and after anterior temporal lobectomy (ATL) using resting-state functional magnetic resonance imaging (rs-fMRI) study and to further observe the correlation between the brain network connectivity with cognitive performance. Fourteen patients with unilateral left MTLE before an...
Source: Epilepsy and Behavior - August 13, 2018 Category: Neurology Source Type: research

Depressive symptoms and suicidality among individuals with epilepsy enrolled in self-management studies: Results from the US Centers for Disease Control and Prevention Managing Epilepsy Well (MEW) Network
We examined correlates of depressive symptoms and suicidal ideation in adults using pooled data from epilepsy self-management studies conducted by sites in the Centers for Disease Control and Prevention (CDC) Research Center's Managing Epilepsy Well (MEW) Network that assessed depression severity with the 9-item Patient Health Questionnaire (PHQ-9). Of the 770 subjects in the analysis (mean age 42.4 ± 13.0 years), the mean total PHQ-9 score was 9.4 ± 6.6 and 334 subjects (43.4%) had moderate to severe depressive symptoms (PHQ-9 ≥ 10). Only ongoing seizures and low education were associated wi...
Source: Epilepsy and Behavior - August 13, 2018 Category: Neurology Source Type: research

Sodium cromoglycate reduces short- and long-term consequences of status epilepticus in rats
Publication date: Available online 13 August 2018Source: Epilepsy & BehaviorAuthor(s): María Guadalupe Valle-Dorado, César Emmanuel Santana-Gómez, Sandra Adela Orozco-Suárez, Luisa RochaAbstractSeveral studies indicate that sodium cromoglycate (CG) induces neuroprotective effects in acute neurological conditions. The present study focused on investigating if the use of CG in rats during the post-status epilepticus (post-SE) period reduces the acute and long-term consequences of seizure activity. Our results revealed that animals that received a single dose of CG (50 mg/kg s.c.: subcutaneou...
Source: Epilepsy and Behavior - August 13, 2018 Category: Neurology Source Type: research

Localizing and lateralizing values of postictal behavioral impairments in epileptic rats
Publication date: Available online 11 August 2018Source: Epilepsy & BehaviorAuthor(s): Lyudmila V. Vinogradova, Alla B. ShatskovaAbstractTransient postictal behavioral impairments in patients with epilepsy provide clues to seizure localization, but no attempt has been made previously to study the localization/lateralization value of postseizure motor disturbances in experimental models of epilepsy. The present study investigated relation of postictal motor deficit to seizure localization in the rat model of sound-induced reflex epilepsy. Sound-induced motor seizures started with a focal brainstem seizure (running) and ...
Source: Epilepsy and Behavior - August 12, 2018 Category: Neurology Source Type: research

Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study
The objective of this study was to characterize the changes in adverse events, seizure severity, and frequency in response to a pharmaceutical formulation of highly purified cannabidiol (CBD; Epidiolex®) in a large, prospective, single-center, open-label study. We initiated CBD in 72 children and 60 adults with treatment-resistant epilepsy (TRE) at 5 mg/kg/day and titrated it up to a maximum dosage of 50 mg/kg/day. At each visit, we monitored treatment adverse events with the adverse events profile (AEP), seizure severity using the Chalfont Seizure Severity Scale (CSSS), and seizure frequency (SF) using seizure cal...
Source: Epilepsy and Behavior - August 9, 2018 Category: Neurology Source Type: research

The impact of sleep characteristics and epilepsy variables on memory performance in patients with focal seizures
In this study, we investigated the relationships between sleep, epilepsy, and objective memory performance variables. Twenty-five patients with focal seizures had their memory tested while undergoing a two-day ambulatory electroencephalography (EEG). The sleep variables of interest were the percentage of time spent in SWS (%SWS) and REM latency. Epilepsy variables included the presence of (1) seizures, (2) interictal epileptiform discharges, and/or (3) hippocampal lesions as well as site of seizure origin (temporal vs extratemporal). Overnight retention (of autobiographical events, a story, and a complex geometric figure) ...
Source: Epilepsy and Behavior - August 8, 2018 Category: Neurology Source Type: research

Comparative effectiveness of add-on therapy with newer-generation antiepileptic drugs in Bulgarian patients with refractory epilepsy
ConclusionDespite some similar characteristics of newer-generation antiepileptic drugs' effectiveness, levetiracetam stands out with better dynamic improvement of seizure severity and frequency and satisfactory tolerability; typical for pregabalin is a very good dynamic improvement of seizure severity and frequency mainly in patients with focal seizures, but a lower tolerability, and the main advantage of oxcarbazepine is a good tolerability, efficacy, however, is less satisfactory. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 8, 2018 Category: Neurology Source Type: research

Navigated transcranial magnetic stimulation for preoperative cortical mapping of expressive language in children: Development of a method
Publication date: Available online 7 August 2018Source: Epilepsy & BehaviorAuthor(s): Gunilla Rejnö-Habte Selassie, Göran Pegenius, Gerd Viggedal, Tove Hallböök, Magnus ThordsteinAbstractWe adjusted an object-naming task with repetitive navigated transcranial magnetic stimulation (rnTMS) originally developed for preoperative cortical language mapping in adults in order for it to be used in children. Two series of pictures were chosen for children above and below 10 years of age, respectively. Firstly, the series of pictures and the preferred speed of presentation were assessed for their applicabil...
Source: Epilepsy and Behavior - August 7, 2018 Category: Neurology Source Type: research

Machine learning as a new paradigm for characterizing localization and lateralization of neuropsychological test data in temporal lobe epilepsy
This study adds to the existing literature by employing an analytic technique with inherent advantages in generalizability when compared to traditional single-sample, not cross-validated models. In the future, class probabilities extracted from these and similar analyses could supplement neuropsychological practice by offering a quantitative guide to clinical judgements. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 3, 2018 Category: Neurology Source Type: research

Depressive, inflammatory, and metabolic factors associated with cognitive impairment in patients with epilepsy
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Josi Arend, Aline Kegler, Ana Letícia Fornari Caprara, Camila Almeida, Patricia Gabbi, Eduardo T. Pascotini, Lori Ane Vargas de Freitas, Cinara Miraglia, Taíse Leitemperger Bertazzo, Raphael Palma, Patrícia Arceno, Marta M.M.F. Duarte, Ana Flavia Furian, Mauro Schneider Oliveira, Luiz Fernando Freire Royes, Gary W. Mathern, Michele Rechia FigheraAbstractPurposeThe purpose of this study was to examine the cognitive function and depressive traits most frequently associated with the clinical assessment of patients with ep...
Source: Epilepsy and Behavior - August 3, 2018 Category: Neurology Source Type: research

Close to 1 million US adults aged 55 years or older have active epilepsy—National Health Interview Survey, 2010, 2013, and 2015
This study uses the most recent data from the 2010, 2013, and 2015 National Health Interview Survey (NHIS) to provide updated national estimates of epilepsy prevalence among US adults aged 55 years or older to help guide public health action. We used the following validated surveillance case definition for active epilepsy: adults with self-reported doctor-diagnosed epilepsy or seizure disorder who reported either currently taking medications to treat their epilepsy or seizure disorder or at least one seizure during the past 12 months. We estimated the prevalence of active epilepsy to be 1.4% (about 529,000) among US ad...
Source: Epilepsy and Behavior - August 2, 2018 Category: Neurology Source Type: research

Perampanel in the treatment of status epilepticus: A systematic review of the literature
ConclusionsThe currently available evidence supporting the use of PER in SE is weak and hampered by several confounding factors. Further studies should be performed in more clinically homogeneous and larger cohorts to evaluate the efficacy and safety of PER administered in earlier stages of SE, at higher dosages, and at intervals shorter than 24 h. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 1, 2018 Category: Neurology Source Type: research

The glucose transporter type 1 (Glut1) syndromes
This article is part of the Special Issue "Individualized Epilepsy Management: Medicines, Surgery and Beyond". (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 1, 2018 Category: Neurology Source Type: research

Unusual ictal propagation patterns suggesting poor prognosis after temporal lobe epilepsy surgery: Switch of lateralization and bilateral asynchrony
ConclusionUnusual ictal propagation patterns are not always related to poor prognosis after surgery in patients with TLE. Patients with unilateral interictal spiking in the temporal region tend to have good outcome despite these unusual patterns. These patterns can also be seen in patients with TLE with other etiologies besides the well-known HS in MRI. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - August 1, 2018 Category: Neurology Source Type: research

Emotion dysregulation in patients with psychogenic nonepileptic seizures: A systematic review based on the extended process model
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Isobel Anne Williams, Liat Levita, Markus ReuberAbstractPsychogenic nonepileptic seizures (PNES) are characterized by paroxysmal alterations in motor and sensory functions resembling epileptic seizures, but are not caused by epileptiform activity. In recent years, there has been increasing scientific interest in emotion dysregulation in patients with PNES (pwPNES), but the literature has not yet been interpreted within a broader model of emotion dysregulation. The aim of this review was therefore to synthesize the existing literature on em...
Source: Epilepsy and Behavior - August 1, 2018 Category: Neurology Source Type: research

Age-related MR characteristics in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE)
ConclusionMagnetic resonance characteristics in patients with MOGHE are age-related and seem to change from subtype I to subtype II probably because of maturational processes between 3 and 6 years. Patchy areas of hypomyelination in histology seem to disappear during brain maturation and may therefore represent the histologic correlate of laminar T2 and FLAIR hyperintensities in subtype I.This article is part of the Special Issue “Individualized Epilepsy Management: Medicines, Surgery and Beyond".Graphical abstract (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 28, 2018 Category: Neurology Source Type: research

Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes
This study extended analysis of the prior report from 12 weeks to 48 weeks of efficacy data and suggested that placebo-controlled randomized trials should be conducted to formally assess the safety and efficacy of CBD in these epileptic encephalopathies. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 27, 2018 Category: Neurology Source Type: research

Influence of weather on seizure frequency — Clinical experience in the emergency room of a tertiary hospital
ConclusionsOur results support the possible influence of the weather on seizure frequency in the overall admissions of the emergency department of a tertiary hospital. In particular, these findings suggest that winter conditions, such as, lower ambient temperatures, higher atmospheric pressure, higher humidity, and reduced sunlight exposure, may have impact in the occurrence of higher incidence of seizures in patients with epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 27, 2018 Category: Neurology Source Type: research

RE: Psychopathological constellation in patients with PNES: A new hypothesis. Martino et al., Epilepsy & Behavior 2018; 78: 297–301
Publication date: Available online 26 July 2018Source: Epilepsy & BehaviorAuthor(s): Marcia Kaplan (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 27, 2018 Category: Neurology Source Type: research

Signs of autonomic arousal precede tilt-induced psychogenic nonsyncopal collapse among youth
Publication date: Available online 25 July 2018Source: Epilepsy & BehaviorAuthor(s): Geoffrey L. Heyer, Rebecca A. Harvey, Monica P. IslamAbstractCharacterizing the physiologic changes leading up to psychogenic nonsyncopal collapse (PNSC) may help to elucidate the processes that cause paroxysmal functional neurological symptom disorders and to clinically distinguish PNSC from syncope. Thus, we aimed to characterize preictal sweat rate, heart rate, and systolic blood pressure changes among patients with tilt-induced PNSC compared to patients with tilt-induced neurally mediated syncope. The presence of increased preictal...
Source: Epilepsy and Behavior - July 25, 2018 Category: Neurology Source Type: research

Surgery for epilepsy in the primary motor cortex: A critical review
Publication date: Available online 23 July 2018Source: Epilepsy & BehaviorAuthor(s): Thomas A. Ostergard, Jonathan P. MillerAbstractSurgical resection of the epileptogenic zone within the frontal lobe can be a very effective treatment for medically refractory epilepsy originating from this area. While much of the frontal lobe consists of highly eloquent tissue, surgery is not necessarily contraindicated as long as the epileptogenic zone is well-localized and the tissue resected is limited. Resection of the primary motor cortex was described by Victor Horsley in the 19th century and was used frequently in the early 20th...
Source: Epilepsy and Behavior - July 23, 2018 Category: Neurology Source Type: research

Patient-reported quality of life and biopsychosocial health outcomes in pediatric epilepsy: An update for healthcare providers
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Gabriel M. Ronen, Peter L. Rosenbaum, Michael H. Boyle, David L. StreinerAbstractIn the 21st century, clinicians are expected to listen to, and understand their patients' views about, their conditions and the effects that these conditions have on their functioning, values, life goals, and welfare. The goals of this review are as follows: (i) to inform, update, and guide clinicians caring for children with epilepsy about developments in the content and new methods of research on patient-reported outcomes, quality of life, and functioning; a...
Source: Epilepsy and Behavior - July 21, 2018 Category: Neurology Source Type: research

Successful treatment of reflex epilepsy with praxis induction by stimulus avoidance only
ConclusionZipai-induced epilepsy may be an unreported subtype form of reflex epilepsy with praxis induction. Nonpharmacological conservative treatment plays a significant role in the treatment of reflex epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 21, 2018 Category: Neurology Source Type: research

Addition of a hospital bedside sitter during intracranial stereotactic EEG monitoring improves safety and seizure responses in an adult epilepsy monitoring unit
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Brad K. Kamitaki, Santoshi Billakota, Lisa M. Bateman, Alison M. PackAbstractExpert consensus statements recommend continuous observation for patients undergoing intracranial electroencephalography (EEG), but this practice is neither universal nor specific regarding the type of observation. We compared outcomes for patients who underwent intracranial stereotactic EEG (SEEG) before and after the adoption of continuous monitoring by a staff bedside sitter.We retrospectively studied 26 consecutive adult patients who underwent SEEG placement a...
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

Metacognitive beliefs and illness perceptions are associated with emotional distress in people with epilepsy
ConclusionMetacognitive beliefs appear to make a greater contribution to anxiety and depression in PWE than illness perceptions. Prospective studies are now needed to establish the causal role of metacognitive beliefs in both the development and persistence of emotional distress. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

Reply to Cubala et al.
Publication date: Available online 19 July 2018Source: Epilepsy & BehaviorAuthor(s): Oh-Young Kwon (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

What really is a ‘gold standard’ in depression recognition among patients with epilepsy?
Publication date: Available online 19 July 2018Source: Epilepsy & BehaviorAuthor(s): Wiesław J. Cubała, Adam Włodarczyk, Mariusz S. Wiglusz, Joanna Szarmach (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

Could Rolandic spikes be a prognostic factor of the neurocognitive outcome of children with BECTS?
Publication date: Available online 19 July 2018Source: Epilepsy & BehaviorAuthor(s): Isabella Tristano, Francesco Nicita, Giacomo Garone, Fabiana Ursitti, Consuelo Nardone, Valerio Rocchi, Cristiana Alessia Guido, Alberto SpaliceAbstractIntroductionRolandic epilepsy, also known as benign childhood epilepsy with centrotemporal spikes (BECTS), is one of the most common epileptic syndromes in previously healthy children. Despite what was known about the benignity of this syndrome, there is always more evidence about the involvement of the cognitive functions with different deficits in several domains to be investigated.Ai...
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

Addressing barriers to surgical evaluation for patients with epilepsy
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Chloe E. Hill, Jackie Raab, Delight Roberts, Timothy Lucas, John Pollard, Ammar Kheder, Brian Litt, Kathryn A. DavisAbstractObjectivePatients with poorly controlled seizures are at elevated risk of epilepsy-related morbidity and mortality. For patients with drug-resistant epilepsy that is focal at onset, epilepsy surgery is the most effective treatment available and offers a 50–80% cure rate. Yet, it is estimated that only 1% of patients with drug-resistant epilepsy undergo surgery in a timely fashion, and delays to surgery completio...
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

Sleep in psychogenic nonepileptic seizures: Time to raise a red flag
Publication date: September 2018Source: Epilepsy & Behavior, Volume 86Author(s): Veronique Latreille, Gaston Baslet, Rani Sarkis, Milena Pavlova, Barbara A. DworetzkyAbstractPoor sleep is a frequent complaint in patients with psychogenic nonepileptic seizures (PNES). However, few studies have examined sleep problems in this population. We aimed to compare sleep complaints in patients with PNES with those with epilepsy. Subjects diagnosed as having PNES by experts using video-electroencephalography (vEEG) were recruited through the Brigham and Women's Hospital epilepsy monitoring unit (EMU) between 3/25/2013 and 3/29/20...
Source: Epilepsy and Behavior - July 20, 2018 Category: Neurology Source Type: research

The efficacy of a short-term multidisciplinary epilepsy program
ConclusionThis study provides promising results with regard to the efficacy of a short-term multidisciplinary epilepsy program. Positive effects could be achieved referring to compliance, activity, and affect. The findings support the relevance of such programs. Subsequent research should focus on the transfer to everyday life. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 18, 2018 Category: Neurology Source Type: research

Deep brain stimulation for epilepsy
Publication date: Available online 17 July 2018Source: Epilepsy & BehaviorAuthor(s): Vicenta SalanovaAbstractThe efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) for epilepsy (SANTE) trial was demonstrated by a randomized trial by Fisher et al. (2010). Based on this trial, the U.S. Food and Drug Administration recently granted approval for DBS therapy for epilepsy; the indication is as follows: “Bilateral stimulation of the anterior nucleus of the thalamus (ANT) for epilepsy is indicated as an adjunctive therapy for reducing the frequency of seizures in individuals...
Source: Epilepsy and Behavior - July 18, 2018 Category: Neurology Source Type: research

Exposure to antiepileptic drugs in pregnancy: The need for a family factor framework
DiscussionFurther work is required to ascertain which family factors are associated with child development in addition to the effects of AED exposure and their potential interaction. As epilepsy may have considerable impact on intrafamily factors and as children are especially vulnerable to such effects, study designs incorporating family factors should be encouraged. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 18, 2018 Category: Neurology Source Type: research

Panic and epilepsy in adults: A systematic review
Publication date: August 2018Source: Epilepsy & Behavior, Volume 85Author(s): Adrienne L. Johnson, Alison C. McLeish, Paula K. Shear, Michael PriviteraAbstractThe purpose of the current paper was to review the empirical literature on the cooccurrence of panic and epilepsy, in order to determine whether there is an increased risk of panic attacks and panic disorder among adults with epilepsy and an increased risk of epilepsy among adults with panic disorder. Given the overlap between panic and ictal fear, a preliminary aim of the current review was to critically evaluate the methodology used to differentiate between dia...
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Effects of valproate on reproductive endocrine function in male patients with epilepsy: A systematic review and meta-analysis
ConclusionsThis meta-analysis indicates that VPA may lead to a significant decrease in the levels of FSH and testosterone and alter the concentrations of LH, DHEAS, SHBG, and ADION to some extent, which might contribute to the reproductive endocrine dysfunction in male patients with epilepsy. It is important for clinical neurologists to be cautious when prescribing VPA to reproductive-aged male patients with epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

MTOR pathway in focal cortical dysplasia type 2: What do we know?
Publication date: August 2018Source: Epilepsy & Behavior, Volume 85Author(s): Fernanda Majolo, Daniel Rodrigo Marinowic, Denise Cantarelli Machado, Jaderson Costa Da CostaAbstractFocal cortical dysplasia (FCD) is the most commonly encountered developmental malformation that causes refractory epilepsy. Focal cortical dysplasia type 2 is one of the most usual neuropathological findings in tissues resected therapeutically from patients with drug-resistant epilepsy. Unlike other types of FCD, it is characterized by laminar disorganization and dysplastic neurons, which compromise the organization of the six histologically k...
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Tolerability of a comprehensive cardiorespiratory monitoring protocol in an epilepsy monitoring unit
ConclusionPatient acceptance of an EMU comprehensive cardiorespiratory monitoring protocol is high. The information obtained from “multimodality recording” should help clinicians and investigators understand the effect of seizures on both cardiac and respiratory physiology, may enhance safety in the EMU, and may aid in the identification of biomarkers for sudden unexpected death in epilepsy (SUDEP). (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Patients with epilepsy care experiences: Comparison between services with and without an epilepsy specialist nurse
This study found that, in comparison to people with epilepsy (PWE) who attended a service without an ESN, PWE who attended a service with an ESN reported receiving greater amount of information, were more involved in their care, perceived care to be better coordinated, and had greater confidence in the information provided and greater comfort in discussing issues with an ESN. They also reported higher rates of satisfaction with the emotional and practical support offered. Thus, it may be concluded that models of care involving the input of ESNs enhance the quality of epilepsy care and care processes. The findings also emph...
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

A qualitative examination and theoretical model of anxiety in adults with epilepsy
ConclusionThis investigation provides a comprehensive account for the development of anxiety in epilepsy, which is consistent with existing theories of anxiety development and maintenance. Importantly, this model provides a foundation for future research and appropriate treatment strategies to address anxiety in people with epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Correlation between clinical and cognitive aspects and nutritional indicators of elderly patients with new-onset epilepsy
Publication date: August 2018Source: Epilepsy & Behavior, Volume 85Author(s): Gloria Maria A.S. Tedrus, Silvana Mariana Screbenich, Tamires Barbosa Nascimento SantosAbstractObjectiveNutritional indicators were correlated with cognitive and clinical aspects of 25 elderly patients with new-onset epilepsy (EPWE). The nutritional indicators of the EPWE were compared with those of a similar control group at a significance level of p 
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

The measurement of both carotid intima-media thickness and epicardial adipose tissue thickness in children with epilepsy receiving antiepileptic drug therapy
ConclusionsIt was determined that carotid intima-media thickness and epicardial adipose tissue thickness were significantly high in children with epilepsy taking long-term antiepileptic drugs. These results demonstrate that these patients could be at increased risk of the development of cardiovascular complications. There is a need for more extensive studies on this subject. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Intellectual outcome after a cortical lesion with versus without epilepsy: A life span neurodevelopmental view
ConclusionPostlesion global IQ, the difference between VIQ and PIQ, and the laterality index all vary significantly as a function of age at lesion onset. In addition, these changes over the life span are all quite different between cases with and without epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Wearable technology in epilepsy: The views of patients, caregivers, and healthcare professionals
ConclusionsUnlike people who have other chronic health conditions, PWE appeared not to be at risk of digital exclusion. This study highlighted a great interest in the use of wearable technology across epilepsy service users, carers, and healthcare professionals, which was independent of demographic and clinical factors and outpaced data security and technology usability concerns. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Sexual dysfunction and associated factors in Chinese Han women with epilepsy
ConclusionsThe associated factors of SD in Chinese Han WWE are multifactorial. The WWE have higher levels of anxiety, poor family economic status, and poor medication adherence. Medical professionals should not only better control seizures but also evaluate and improve patients' sexual function so as to improve the quality of life of WWE. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Marriage in epilepsy: The impact of the question in knowledge, attitude, and practice surveys
ConclusionsPersonal questions probing the possibility of marriage of self or family members to someone with epilepsy bring about negative attitudes more often than generic questions inquiring the marriage-worthiness of PWE. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Utilization of brain imaging in evaluating patients with psychogenic nonepileptic spells
ConclusionsThese findings suggest that the frequency of brain imaging obtained prior to the definitive diagnosis of PNES is influenced by semiology of spells and the psychiatric health of patients. Patients who demonstrate minimal paroxysmal movements in the settings of multiple psychiatric comorbidities represent a particularly challenging patient phenotype which is linked to more frequent referrals for brain imaging. These patients should be promptly referred for vEEG to improve diagnostic accuracy and prevent treatment with anticonvulsants as well as referrals for serial neurodiagnostic tests. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research

Future development of a depot antiepileptic drug: What are the ethical implications?
Publication date: August 2018Source: Epilepsy & Behavior, Volume 85Author(s): Alexandra J. Sequeira, Stephanie Buchman, Ariane Lewis, Steven KarceskiAbstractDepot medications have been used for long-term treatment of many different medical conditions (schizophrenia, opioid addiction) and for prevention of pregnancy (birth control). In addition, proposals for depot medication for antidepressants have been made as a possible treatment for chronic depression. For the treatment of chronic epilepsy, there are currently no depot antiepileptic drugs (AEDs). However, there may be a role for them. Depot AEDs could improve medic...
Source: Epilepsy and Behavior - July 17, 2018 Category: Neurology Source Type: research