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Cognition, health-related quality of life, and mood in children and young adults diagnosed with a glioneuronal tumor in childhood
Conclusion Although lower than in corresponding reference groups, cognitive outcome and HRQoL are good provided that seizure freedom or at least a low seizure severity can be achieved. There is a risk of elevated levels of psychiatric symptoms. Long-term clinical follow-up is advisable. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 11, 2018 Category: Neurology Source Type: research

Response to letter to editor regarding: EB_2017_222_R1 frequency and predictors of psychological distress after a diagnosis of epilepsy: A community-based study: Methodological issues
Publication date: Available online 9 April 2018 Source:Epilepsy & Behavior Author(s): Ying Xu, Qiang Li, Craig S. Anderson (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

Prodrome in epilepsy
Conclusions Prodromes are characterized by a broad spectrum of preictal symptoms that may be experienced for a duration of between 10min and several days, which usually persist until seizure onset. Opinion is divided on their precise nature and value as predictors of seizures. A greater understanding of prodromes might offer insights into the preictal period and hold promise for new seizure management therapies. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

Long-term effects of adjunctive perampanel on cognition in adolescents with partial seizures
Conclusions In keeping with the 19-week double-blind phase, long-term adjunctive treatment with perampanel did not have any significant overall effects on the CDR system global cognition score in adolescent patients with inadequately controlled partial seizures. Similar trends were observed across the individual CDR system domains. Adjunctive perampanel showed sustained long-term seizure control and had a safety and tolerability profile similar to that observed in prior clinical studies. Graphical abstract (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

Investigation of microstructural abnormalities in white and gray matter around hippocampus with diffusion tensor imaging (DTI) in temporal lobe epilepsy (TLE)
Conclusion Diffusion tensor imaging can detect microstructural abnormalities in brain from patients with TLE, which might be hard to find with routine Magnetic Resonance Imaging (MRI) sequence. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

Leading up to saying "yes": A qualitative study on the experience of patients with refractory epilepsy regarding presurgical investigation for resective surgery
Conclusion Qualitative inquiry detailed multifaceted effects of information on patients' overall treatment trajectory and experience of healthcare. Earlier patient identification for surgical assessments should be accompanied by access to good quality information at primary and community care levels and strengthened referral processes. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

Trends in resource utilization and prescription of anticonvulsants for patients with active epilepsy in Germany from 2003 to 2013 — A ten-year overview
This study evaluated trends in resource use and prescription patterns in patients with active epilepsy over a 10-year period at the same outpatient clinic of a German epilepsy center. We analyzed a cross-sectional patient sample of consecutive adults with active epilepsy over a 3-month period in 2013 and compared them with equally acquired data from the years 2003 and 2008. Using validated patient questionnaires, data on socioeconomic status, course of epilepsy, as well as direct and indirect costs were recorded. A total of 198 patients (mean age: 39.6±15.0years, 49.5% male) were enrolled and compared with our previ...
Source: Epilepsy and Behavior - April 10, 2018 Category: Neurology Source Type: research

The relevance of attention deficit hyperactivity disorder in self-limited childhood epilepsy with centrotemporal spikes
In conclusion, patients with BCECTS and ADHD had worse executive and attentional performance compared with controls than non-ADHD patients with BCECTS. Regardless of the presence of epilepsy, ADHD also negatively impacted executive and attentional functions but in different executive subdomains compared with patients with epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 9, 2018 Category: Neurology Source Type: research

Investigating the awareness, behavior, and attitude toward epilepsy among university students in Benghazi, Libya
Conclusion There is a reasonable level of awareness regarding epilepsy among Libyan students, though a lack of accuracy in the acquired knowledge exists. The ancient misconceptions regarding the nature of epilepsy and negative attitudes toward PWE appear to be rather common among the Libyan students. Consequently, the discrepancies in the views between the two surveys concerning the ways in which epilepsy is perceived and PWE are treated were extremely evident, thus reflecting the already established view that epilepsy faces greater stigma as a health condition in developing countries in comparison with Western nations. (S...
Source: Epilepsy and Behavior - April 8, 2018 Category: Neurology Source Type: research

Parkinson's disease, epileptic seizures, and sudden death: Three faces of the same coin
Publication date: Available online 7 April 2018 Source:Epilepsy & Behavior Author(s): Fulvio A. Scorza, Antonio-Carlos G. de Almeida, Ana C. Fiorini, Carla A. Scorza, Josef Finsterer (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 7, 2018 Category: Neurology Source Type: research

Tuberous sclerosis complex: Concerns and needs of patients and parents from the transitional period to adulthood
Conclusion The current study provides patient-driven information, allowing recommendations to facilitate the (transition of) care for young adults with TSC. In addition to seizures, tumor growth, and TSC-associated neuropsychiatric disorders (TAND), more attention is needed for concerns and care needs specific to the transitional period, participation, and environmental factors. Adult healthcare providers should offer expert multidisciplinary care for adult patients with TSC, including attention for parental stress. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 7, 2018 Category: Neurology Source Type: research

Presurgical depression and anxiety are not associated with worse epilepsy surgery outcome five years postoperatively
Conclusion These findings from a prospective study that utilized a standardized protocol for psychiatric and seizure outcome assessment suggest that presurgical mood disorders have no substantial impact on postsurgical seizure outcome for up to five years after surgery. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 7, 2018 Category: Neurology Source Type: research

Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life
Conclusions This study supports the positive benefits of epilepsy surgery on depression, anxiety, and QOL in Hispanic, primarily undocumented immigrant, Spanish-speaking people with epilepsy (PWE) in the US. These results are useful for educating this particular population about the possible benefits of surgery for IE and can enhance presurgical counseling. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 7, 2018 Category: Neurology Source Type: research

Support values through the eyes of the patient
Publication date: May 2018 Source:Epilepsy & Behavior, Volume 82 Author(s): Wil H.E. Buntinx, Francis Y. Tan, Albert P. Aldenkamp A significant group of persons affected by refractory epilepsy require a wide range of long-term support from professionals as well as informal support givers. To enhance person-centeredness, it is important to know which patient values are associated with long-term support. An Internet survey produced a total of 1176 statements from 289 persons with epilepsy for analysis. Statements were expressed in the respondent's own words and were related to positive experiences (704) as well as p...
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Serial changes in the paroxysmal discharges in rolandic epilepsy may predict seizure recurrence: A retrospective 3-year follow-up study
Conclusion Our study demonstrates that extended periods of high frequency of paroxysmal discharges, initial frontal EEG focus, and persistence of awake interictal abnormalities are highly effective in predicting seizure recurrence in patients with rolandic epilepsy (RE). (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Morphometric MRI features and surgical outcome in patients with epilepsy related to hippocampal sclerosis and low intellectual quotient
Conclusions This is the first study of a series of patients with pure MTLE-HS, including those with low IQ and their morphometric magnetic resonance imaging (MRI) features using FreeSurfer. Although patients with lower intellectual scores presented more areas of brain atrophy, IQ was not a predictor of surgical outcome. Therefore, when evaluating seizure follow-up, low IQ in patients with MTLE-HS might not contraindicate resective surgery. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Usage of EpiFinder clinical decision support in the assessment of epilepsy
Conclusion The initial testing of the EpiFinder algorithm suggests possible utility in differentiating between an epilepsy syndrome and an alternative diagnosis in adult patients. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Off-label use and manipulations of antiepileptic drugs in children: Analysis of the outpatient prescriptions in a tertiary center
Conclusion Off-label use and manipulations of AEDs remain an important problem in home care of children with epilepsy. This is mainly a concern for the most vulnerable groups, i.e., young patients, patients undergoing polytherapy, and patients with developmental and epileptic encephalopathy (DEE). International initiatives have been launched to improve the availability of labeled and adapted drugs in this population. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Epilepsy-related concerns among patients with epilepsy in West China
Conclusion Our findings indicated that Chinese adults with epilepsy had various concerns, some of which differed from those observed in Western populations. Concerns about heritability of seizures, marriage, and pregnancy were of greater concern to Chinese patients compared with Western patients while the legal right to drive appeared to be less of a concern to Chinese patients. Patients with controlled seizures may still have many concerns. Chinese physicians should monitor patient concerns even among those whose seizures remain controlled to meet their needs. More time and attention should be given to address these issue...
Source: Epilepsy and Behavior - April 4, 2018 Category: Neurology Source Type: research

Psychiatric and cognitive adverse events: A pooled analysis of three phase III trials of adjunctive eslicarbazepine acetate for partial-onset seizures
Conclusions In phase III clinical trials of adjunctive ESL for treatment-refractory POS, psychiatric and cognitive TEAEs were reported infrequently with ESL and placebo. The incidences of depression and suicidality-related TEAEs and of cognitive TEAEs were higher for patients taking ESL vs. placebo. Incidences of psychiatric and cognitive SAEs, and TEAEs leading to discontinuation, were low with ESL and placebo. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 29, 2018 Category: Neurology Source Type: research

Development and psychometric evaluation of the youth and parent versions of the Epilepsy Disclosure Scale (EDS)
Conclusion Prior to the development of these instruments, no valid and reliable measures existed that could suitably capture disclosure amongst populations living with epilepsy. The youth and parent versions of the EDS are valid, reliable, brief, and easily administered and thus could prove useful in research as well as in the clinical setting. These scales will enable researchers and clinicians to profile the epilepsy disclosure behaviors of YWE and their parents, which play an important role and have implications both for the psychosocial wellbeing of families living with epilepsy and for epilepsy-related stigma. (Source...
Source: Epilepsy and Behavior - March 28, 2018 Category: Neurology Source Type: research

Diagnostic value of Status Epilepticus Severity Score for survival conditions of patients with status epilepticus: A PRISMA-compliant systematic review and meta-analysis
Conclusions The STESS is a promising candidate for predicting survival condition of patients with SE. However, the potential tool should be validated in well-designed studies with larger sample sizes. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 28, 2018 Category: Neurology Source Type: research

Considering developing a specialized epilepsy employment program? The PEP Jobs Program paradigm
Publication date: Available online 26 March 2018 Source:Epilepsy & Behavior Author(s): Robert T. Fraser, Peter B. Weber, Kenneth D. Laxer, Thomas Post (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 27, 2018 Category: Neurology Source Type: research

Emotional reactivity in mesial temporal lobe epilepsy: A pilot study
Conclusions Patients with MTLE seem to feel the environment in a more sensitive and positive way compared with controls, likely in relationship with social functioning alterations. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 27, 2018 Category: Neurology Source Type: research

Juvenile myoclonic epilepsy refractory to treatment in a tertiary referral center
Discussion Juvenile myoclonic epilepsy is often regarded as a benign epileptic syndrome, but in this setting, half of the individuals with JME have refractory epilepsy with only about a quarter of those seizure-free in the previous year. Despite some advances in the understanding of this syndrome, there is still much to do before we can offer all the best outcomes. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 27, 2018 Category: Neurology Source Type: research

Diazepam for outpatient treatment of nonconvulsive status epilepticus in pediatric patients with Angelman syndrome
Publication date: May 2018 Source:Epilepsy & Behavior, Volume 82 Author(s): Lila Worden, Olivia Grocott, Amanda Tourjee, Fonda Chan, Ronald Thibert Nonconvulsive status epilepticus (NCSE) is present in multiple pediatric neurogenetic syndromes with epileptic encephalopathies. While intravenous (IV) medications are used inpatient for treatment of critical illness-related NCSE, there is no consensus on treatment of ambulatory NCSE. Up to 50% of patients with Angelman syndrome (AS) have NCSE with myoclonic or atypical absence status. Here we report our experience in pediatric patients with AS and NCSE treated outpati...
Source: Epilepsy and Behavior - March 27, 2018 Category: Neurology Source Type: research

Antiepileptic drug treatment of generalized tonic –clonic seizures: An evaluation of regulatory data and five criteria for drug selection
Conclusion Ultimately, the choice of AED depends on all these factors but particularly on efficacy and adverse effects. Different patients will weigh the various factors differently, and the role of the treating physician is to provide accurate information to allow patients to make informed choices. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 27, 2018 Category: Neurology Source Type: research

Role of β2/3-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis
Conclusion These findings demonstrate that β2/3-selective PAMs can moderately retard experimental epileptogenesis, indicating the protective role of β2/3-subunit GABA-A receptor isoforms in the development of epilepsy. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 26, 2018 Category: Neurology Source Type: research

Nonconvulsive status epilepticus after cessation of convulsive status epilepticus in pediatric intensive care unit patients
Publication date: May 2018 Source:Epilepsy & Behavior, Volume 82 Author(s): Jin Chen, Lingling Xie, Yue Hu, Xinghui Lan, Li Jiang Little is known about pediatric patients suffering from nonconvulsive status epilepticus (NCSE) after convulsive status epilepticus (CSE) cessation. The aim of this study was to identify in pediatric patients the clinical characteristics of NCSE after CSE cessation and the factors that contribute to patient outcomes. Data from clinical features, electroencephalography (EEG) characteristics, neuroimaging findings, treatments, and prognosis were systematically summarized, and the associat...
Source: Epilepsy and Behavior - March 26, 2018 Category: Neurology Source Type: research

Characteristics and healthcare situation of adult patients with tuberous sclerosis complex in German epilepsy centers
Conclusion Despite TSC being a multisystem disorder causing considerable impairment, every fifth adult patient is self-sustaining or living with a partner. In clinical practice, uncontrolled epilepsy and renal angiomyolipoma are of major importance in adult patients with TSC. Most patients suffer from focal or multifocal epilepsy, but epilepsy surgery is performed in less than 10% of these patients. Interdisciplinary TSC centers may help to optimize the management of patients with TSC regardless of age and ensure early and adequate treatment that also considers the advances in new therapeutic options. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 26, 2018 Category: Neurology Source Type: research

Surgical versus medical treatment of drug-resistant epilepsy: A systematic review and meta-analysis
Conclusion As the complications of interventions, declines in memory, and word recall/naming were not assessed in the meta-analysis, the conclusions are limited to seizure-free, AED use, and QOL. The current evidence indicate that compared with medical treatment, surgery is more likely to achieve seizure-free, off AEDs, and better QOL. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Cognitive and clinical variables associated with interictal dysphoric disorder in patients with epilepsy
Conclusion The occurrence of IDD was high. Interictal dysphoric disorder was found in different epileptic syndromes, and it was associated with the presence of PD, depressive episodes, lower performance in VF, and lower quality of life (QoL). (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Pregnancy outcomes among women with epilepsy: A retrospective cohort study
Conclusions Pregnancies with epilepsy, even in cases with multidisciplinary care and no other risk factors, are still significantly associated with higher adverse outcomes. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Clinical and electrophysiological findings in patients with phenylketonuria and epilepsy: Reflex features
Conclusion Reports on the clinical and electrophysiological features of adult patients with PKU were scant. We emphasized that reflex clinical features may be observed in this metabolic disease, and focal epileptiform abnormalities and asymmetry may be present in electrophysiological evaluation besides the rare association with HS. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Proliferative hippocampal activity in a group of patients with Rasmussen's encephalitis: Neuronal, glial, and BDNF tissue expression correlations
In this study, we investigated the correlation between inflammation and epilepsy as well as the rates of hippocampal gliogenesis and neurogenesis in a pediatric group of six patients with RE and six control cases. The dentate gyrus (DG) samples were obtained from patients who underwent surgery for intractable RE. Sections were processed for immunohistochemistry using antibodies against sex determining region Y-box 2 (Sox2), nestin, human protein encoded by MKI67 gen (Ki67), and brain-derived neurotrophic factor (BDNF). There was an increase in the number of Ki67-positive granule cells in the DG of patients with RE in compa...
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Anti-GAD antibodies in a cohort of neuropsychiatric patients
Conclusion Antiglutamate decarboxylase (anti-GAD) antibodies relate to epilepsy with or without cognitive complaints. However, psychiatric symptoms were almost absent in anti-GAD positive patients, and the presence of anti-GAD antibodies contributed little to the prognosis in our cohort. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

A systematic review of quality of life in parents of children with epilepsy
Publication date: May 2018 Source:Epilepsy & Behavior, Volume 82 Author(s): Klajdi Puka, Tamara P. Tavares, Kelly K. Anderson, Mark A. Ferro, Kathy N. Speechley Objectives This systematic review aimed to 1) describe the quality of life (QOL) of parents of children with childhood-onset epilepsy (CWE), 2) identify factors associated with parental QOL, and 3) evaluate the association between parents' QOL and children's psychological well-being. Methods We conducted a comprehensive search of MEDLINE, EMBASE, and PsycINFO and conducted forward and backward citation tracking. A total of 15 articles met inclusion criteri...
Source: Epilepsy and Behavior - March 24, 2018 Category: Neurology Source Type: research

Electrocorticographic high-gamma language mapping: Limitations of comparisons with electrocortical stimulation
Publication date: Available online 22 March 2018 Source:Epilepsy & Behavior Author(s): Ravindra Arya, Nathan E. Crone (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 23, 2018 Category: Neurology Source Type: research

Deep facial analysis: A new phase I epilepsy evaluation using computer vision
Publication date: May 2018 Source:Epilepsy & Behavior, Volume 82 Author(s): David Ahmedt-Aristizabal, Clinton Fookes, Kien Nguyen, Simon Denman, Sridha Sridharan, Sasha Dionisio Semiology observation and characterization play a major role in the presurgical evaluation of epilepsy. However, the interpretation of patient movements has subjective and intrinsic challenges. In this paper, we develop approaches to attempt to automatically extract and classify semiological patterns from facial expressions. We address limitations of existing computer-based analytical approaches of epilepsy monitoring, where facial movemen...
Source: Epilepsy and Behavior - March 23, 2018 Category: Neurology Source Type: research

People with epilepsy and their relatives want more information about risks of injuries and premature death
This study demonstrates that there is a considerable gap between what the patients want regarding information and what they are actually given by healthcare providers. Graphical abstract (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 23, 2018 Category: Neurology Source Type: research

The relevance of timing in nonconvulsive status epilepticus: A series of 38 cases
Conclusions There were pervasive delays in all phases of NCSE management. Delays in hospital arrival or treatment initiation may result in prolonged TTC. Recognition of in-hospital episodes may be more delayed, which may lead to poorer prognosis in these cases. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 23, 2018 Category: Neurology Source Type: research

Gender differences in prevalence of psychiatric disorders, levels of alexithymia, and coping strategies in patients with refractory mesial temporal epilepsy and comorbid psychogenic nonepileptic seizures
Conclusions There are significant gender differences in psychiatric, clinical, and sociodemographic aspects in a group of patients with TLE-MTS and PNES, as well as in quality of life, levels of alexithymia, anxiety/depressive symptoms, and coping strategies. These gender differences suggest that specific approaches might be adopted depending on the patient's gender and, consequently, their distinct psychological/psychiatric profile. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 23, 2018 Category: Neurology Source Type: research

Can a collaborative healthcare network improve the care of people with epilepsy?
Publication date: Available online 21 March 2018 Source:Epilepsy & Behavior Author(s): Ejaz A. Shamim, Ketan Mane, Tobias Loddenkemper, Alan Leviton New opportunities are now available to improve care in ways not possible previously. Information contained in electronic medical records can now be shared without identifying patients. With network collaboration, large numbers of medical records can be searched to identify patients most like the one whose complex medical situation challenges the physician. The clinical effectiveness of different treatment strategies can be assessed rapidly to help the clinician decide...
Source: Epilepsy and Behavior - March 22, 2018 Category: Neurology Source Type: research

Adults with an epilepsy history, especially those 45years or older, those with lower family incomes, and those with a history of hypertension, report a history of stroke five times as often as adults without such a history —2010, 2013, and 2015 U.S. National Health Interview Survey
Publication date: Available online 22 March 2018 Source:Epilepsy & Behavior Author(s): Matthew M. Zack, Cecily Luncheon (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 22, 2018 Category: Neurology Source Type: research

Reply to “Therapeutic management of people with epilepsy in low- and middle-income countries”
Publication date: Available online 22 March 2018 Source:Epilepsy & Behavior Author(s): Jeremy Jost, Pierre-Marie Preux (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 22, 2018 Category: Neurology Source Type: research

A brief history of typical absence seizures — Petit mal revisited
Publication date: March 2018 Source:Epilepsy & Behavior, Volume 80 Author(s): Francesco Brigo, Eugen Trinka, Simona Lattanzi, Nicola Luigi Bragazzi, Raffaele Nardone, Mariano Martini In this article, we have traced back the history of typical absence seizures, from their initial clinical description to the more recent nosological position. The first description of absence seizures was made by Poupart in 1705 and Tissot in 1770. In 1824, Calmeil introduced the term “absences”, and in 1838, Esquirol for the first time used the term petit mal. Reynolds instead used the term “epilepsia mitior” ...
Source: Epilepsy and Behavior - March 21, 2018 Category: Neurology Source Type: research

International Epilepsy Day: Celebrating a global day for epilepsy
Publication date: March 2018 Source:Epilepsy & Behavior, Volume 80 Author(s): Ann Little (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 21, 2018 Category: Neurology Source Type: research

Task activation and functional connectivity show concordant memory laterality in temporal lobe epilepsy
Publication date: April 2018 Source:Epilepsy & Behavior, Volume 81 Author(s): Noah Sideman, Ganne Chaitanya, Xiaosong He, Gaelle Doucet, Na Young Kim, Michael R. Sperling, Ashwini D. Sharan, Joseph I. Tracy Objective In epilepsy, asymmetries in the organization of mesial temporal lobe (MTL) functions help determine the cognitive risk associated with procedures such as anterior temporal lobectomy. Past studies have investigated the change/shift in a visual episodic memory laterality index (LI) in mesial temporal lobe structures through functional magnetic resonance imaging (fMRI) task activations. Here, we examine ...
Source: Epilepsy and Behavior - March 20, 2018 Category: Neurology Source Type: research

A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf –Hirschhorn syndrome
This study design is susceptible to possible bias, as the data are largely drawn from caregiver report and investigators had limited access to medical records. Despite this, our data suggest that the genetic etiology of seizures, together with an accurate electroclinical delineation, are important components of drug selection, even in contiguous gene syndromes which may have complex seizure etiologies. (Source: Epilepsy and Behavior)
Source: Epilepsy and Behavior - March 20, 2018 Category: Neurology Source Type: research

A review of mobile apps for epilepsy self-management
Publication date: April 2018 Source:Epilepsy & Behavior, Volume 81 Author(s): Cam Escoffery, Robin McGee, Jonathan Bidwell, Christopher Sims, Eliana Kovitch Thropp, Cherise Frazier, Elizabeth D. Mynatt Mobile health app developers increasingly are interested in supporting the daily self-care of people with chronic conditions. The purpose of this study was to review mobile applications (apps) to promote epilepsy self-management. It investigates the following: 1) the available mobile apps for epilepsy, 2) how these apps support patient education and self-management (SM), and 3) their usefulness in supporting managem...
Source: Epilepsy and Behavior - March 20, 2018 Category: Neurology Source Type: research