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Total 384 results found since Jan 2013.
Susceptibility Weighted MRI and Regional Cerebrovascular Reservoir Capacity in Angiography Proven Large Artery Disease in Acute Ischemic Stroke and Transient Ischemic Attack (P6.247)
CONCLUSIONS:Cortical vessel signs on susceptibility-weighted image have an association with regional cerebrovascular reservoir capacity. And this snapshout image would be a useful tool in the real world of clinical practice in evaluating cerebrovascular perfusion status. But longer follow up in much larger populations are needed.Disclosure: Dr. Lee has nothing to disclose. Dr. Won has nothing to disclose. Dr. Yoo has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lee, S. B., Won, Y. D., Yoo, D.-S. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research
Crossed cerebellar diaschisis after stroke identified noninvasively with cerebral blood flow-weighted arterial spin labeling MRI
Conclusions CCD correlated with cerebellar CVR asymmetry and Wallerian degeneration. These findings suggest that noninvasive MRI may be a useful alternative to PET or SPECT to study structural correlates and clinical consequences of CCD following supratentorial stroke.
Source: European Journal of Radiology - November 10, 2015 Category: Radiology Source Type: research
A review of the evidence of zolpidem efficacy in neurological disability after brain damage due to stroke, trauma and hypoxia: A justification of further clinical trials.
Authors: Sutton JA, Clauss RP
Abstract
During 15 years, 23 clinical reports and 6 studies have demonstrated associations between sub-sedative doses of zolpidem and recoveries from brain damage due to strokes, trauma and hypoxia. Clinical findings include unexpected awakenings from vegetative states and regressions of stroke symptoms after dosing that disappear during elimination and reappear on repeat dosing. Initially single-photon emission computed tomography scans showed improved perfusion within, around and distant from infarctions. Then positron emission tomography scans and electroencephalography detected ren...
Source: Brain Injury - May 24, 2017 Category: Neurology Tags: Brain Inj Source Type: research
Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke
Conclusion: Direct inhibition of smooth muscle myosin by AmBleb in pre-capillary SMCs significantly contribute to the improvement of cerebral blood reperfusion and brain functions suggesting that smooth muscle myosin inhibition may have promising potential in stroke therapies as a follow-up treatment of physical or chemical removal of the occluding thrombus.
Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: M á t é P é nzes, Demeter T ú r ó s, Domokos M á th é , Kriszti á n Szigeti, Nikolett Heged ű s, Anna Á gnes Rauscher, P é ter T ó th, Ivan Ivic, Parasuraman Padmanabhan, Gabriella P á l, Á rp á d Dobolyi, M á t é Gyimesi, Andr á s M Tags: Research Paper Source Type: research
Brain perfusion single photon emission computed tomography abnormality in MRI-negative stroke-like patients post COVID-19 vaccination
Stroke-like symptoms after COVID-19 vaccination was thought to be functional if there was no anatomical image abnormality. We aimed to analyze brain perfusion changes in these patients. A case-control study of brain perfusion single photon emission computed tomography (SPECT) of 12 vaccinated patients with left-sided stroke-like symptoms were compared with 12 age- and gender-matched normal interictal brain SPECTs using voxel-based analysis. Significant hyperperfusion was seen on the right side in postcentral, inferior parietal, mid temporal, parahippocampal, and caudate regions, and on the left side in the thalamus, hippoc...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
De Novo Ivy Sign Indicates Postoperative Hyperperfusion in Moyamoya Disease Brief Reports
Conclusions—
In MMD, a de novo ivy sign could indicate postoperative hyperperfusion after bypass, which is not always correlated with preoperative hemodynamic impairment. Additional factors other than preoperative cerebral hemodynamics might be involved in postoperative hyperperfusion in MMD.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Horie, N., Morikawa, M., Morofuji, Y., Hiu, T., Izumo, T., Hayashi, K., Nagata, I. Tags: Other Stroke Treatment - Surgical Brief Reports Source Type: research
Searching for Salvageable Brain: The Detection of Ischemic Penumbra Using Various Imaging Modalities?
Various imaging modalities are used to identify the ischemic penumbra in patients with acute ischemic stroke. Although single-photon emission computed tomography (CT), perfusion-weighted magnetic resonance imaging (MRI), and perfusion CT are used to evaluate residual cerebral blood flow in the ischemic area, validation of the perfusion threshold for the penumbra has not been established. The ischemic core corresponds generally to areas with early ischemic changes, such as parenchymal hypoattenuation on CT, restricted apparent diffusion coefficient on diffusion-weighted MRI, or very low cerebral blood volume on perfusion C...
Source: Journal of Stroke and Cerebrovascular Diseases - November 18, 2013 Category: Neurology Authors: Teruyuki Hirano Tags: Review Articles Source Type: research
Utility of Early Post-treatment Single-Photon Emission Computed Tomography Imaging to Predict Outcome in Stroke Patients Treated with Intravenous Tissue Plasminogen Activator
It is important to predict the outcome of tissue plasminogen activator (tPA)–treated patients early after the treatment for considering the post-tPA treatment option. We assessed cerebral blood flow (CBF) of tPA-treated patients with single-photon emission computed tomography (SPECT) 1 hour after tPA infusion to predict the patient outcome. Technetium-99m-hexamethylpropyleneamine oxime SPECT was performed in 35 consecutive tPA-treated patients. Asymmetry index, a contralateral-to-ipsilateral ratio of CBF, was calculated to analyze CBF quantitatively. Hypoperfusion or hyperperfusion was defined as a decrease of 25% or mor...
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2013 Category: Neurology Authors: Takeo Abumiya, Masahito Katoh, Takuya Moriwaki, Masami Yoshino, Takeshi Aoki, Hiroyuki Imamura, Toshimitsu Aida, Hideo Scichinohe, Naoki Nakayama, Ken Kazumata, Kiyohiro Houkin Tags: Original Articles Source Type: research
A dual-labeled Annexin A5 is not suited for SPECT imaging of brain cell death in experimental murine stroke
; Andreas Wunder
Source: Journal of Cerebral Blood Flow - July 2, 2014 Category: Neurology Authors: Marietta ZilleDenise HarhausenMarijke De Saint-HubertRoger MichelChris P ReutelingspergerUlrich DirnaglAndreas Wunder Tags: apoptosis cerebral ischemia mouse phophatidylserine single-photon emission computed tomography Source Type: research
Pharmacokinetic parameters of I-123 iomazenil can predict the risk of ischemic stroke
Conclusions IMZ-EF calculated from IMZ SPECT and CBF PET or SPECT was suggested to be an indicator predicting the risk of cerebrovascular diseases.
Source: Journal of Nuclear Medicine - May 23, 2016 Category: Nuclear Medicine Authors: Kato, H., Isohashi, K., Watabe, T., Kanai, Y., Naka, S., Tatsumi, M., Shimosegawa, E., Hatazawa, J. Tags: MTA II: Neurology Posters Source Type: research
Acute Hearing Loss Caused by Decreasing Anterior Inferior Cerebellar Arterial Perfusion in a Patient with Vertebral Artery Stenosis
We report a case of bilateral hearing loss caused by decreased vascular flow in the anterior inferior cerebellar artery (AICA) territory. A 74-year-old man who experienced right hearing loss 5 months ago presented with bilateral deafness and right cerebellar ataxia; however, no ischemic lesion was detected in the bilateral AICA area. After stroke treatment, hearing loss was improved. One month later, we obtained blood flow improvement in the left AICA territory on single –photon-emission computed tomography and vertebral artery stenosis on magnetic resonance angiography.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2017 Category: Neurology Authors: Rintaro Fukuda, Nobukazu Miyamoto, Arisa Hayashida, Yuji Ueno, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Case Studies Source Type: research
Positional Brain Single-Photon Emission Computed Tomography Findings in a Case of Limb-Shaking Syndrome
An 84-year-old man, who presented lower limbs limb-shaking syndrome at orthostatism lasting a few seconds, was referred in our stroke unit. Magnetic resonance imaging showed an acute infarction in the right thalamus and the insular cortex, left extracranial carotid stenosis at 80%, and low flow in the right middle cerebral artery but did not explain limb-shaking syndrome symptomatology. We performed comparative positional brain perfusion single-photon emission computed tomography (SPECT), in the upright and in the supine position, to explore and localize hypoperfusion-endangered brain structures that may be involved in the...
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2017 Category: Neurology Authors: Caroline Bund, C éline Heimburger, Valérie Wolff, Izzie Jacques Namer Tags: Case Report Source Type: research
Impact of cortical hemodynamic failure on both subsequent hemorrhagic stroke and effect of bypass surgery in hemorrhagic moyamoya disease: a supplementary analysis of the Japan Adult Moyamoya Trial.
CONCLUSIONS: Hemodynamic failure is an independent risk factor for subsequent hemorrhage in hemorrhagic moyamoya disease. Direct bypass surgery showed a significant preventive effect in the hemodynamically impaired hemispheres. Thus, hemodynamic failure, as well as previously proposed factors such as choroidal anastomosis, should be considered for the surgical indication in hemorrhagic moyamoya disease.Clinical trial registration no.: C000000166 (umin.ac.jp).
PMID: 32168484 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 12, 2020 Category: Neurosurgery Authors: Takahashi JC, Funaki T, Houkin K, Kuroda S, Fujimura M, Tomata Y, Miyamoto S Tags: J Neurosurg Source Type: research
Preoperatively estimated graft flow rate contributes to the improvement of hemodynamics in revascularization for Moyamoya disease
Moyamoya disease is a cerebrovascular disease that is characterized by chronic progressive stenosis of the terminal portion of the internal carotid artery (ICA) on both sides of the brain, which results in an abnormal vascular network of the collateral pathways at the base of the brain.1,2 Therefore, patients with Moyamoya disease have a decreased cerebral blood flow (CBF) and reduced cerebral perfusion pressure,3 which can result in ischemic and/or hemorrhagic stroke. This hemodynamic condition can be evaluated using positron emission tomography (PET) or single-photon emission computed tomography (SPECT) as the gold standard procedure.
Source: Journal of Stroke and Cerebrovascular Diseases - November 7, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Katsuya Komatsu, Yusuke Kimura, Sangnyon Kim, Kei Miyata, Yukinori Akiyama, Rei Enatsu, Toru Hirano, Nobuhiro Mikuni Source Type: research
