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Total 384 results found since Jan 2013.

Radionuclide Imaging in Ischemic Stroke
Ischemic stroke is caused by interruption or significant impairment of blood supply to the brain, which leads to a cascade of metabolic and molecular alterations resulting in functional disturbance and morphologic damage. The changes in regional cerebral blood flow and regional metabolism can be assessed by radionuclide imaging, especially SPECT and PET. SPECT and PET have broadened our understanding of flow and metabolic thresholds critical for maintenance of brain function and morphology: PET was essential in the transfer of the concept of the penumbra to clinical stroke and thereby had a great impact on developing treat...
Source: Journal of Nuclear Medicine - November 3, 2014 Category: Radiology Authors: Heiss, W.-D. Tags: Continuing Education Source Type: research

Hyperdopaminergism in Lenticulostriate Stroke-Induced Restless Legs Syndrome: A Neuro Imaging Study (P7.303)
CONCLUSIONS: A systematic study of small lesions associated with RLS may contribute to understanding the pathophysiological mechanisms underlying this condition. In this regard, the body of the caudate nucleus might be an important structure. The isotopic results reinforce the hypothesis of an increased dopaminergic tone in the striatum as part of RLS pathophysiology. Thus, the efficacy with low doses of dopaminergic agonists in RLS could be explained by stimulation of inhibitory D2-like autoreceptors.Disclosure: Dr. Ruppert has nothing to disclose. Dr. Bataillard has nothing to disclose. Dr. Namer has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ruppert, E., Bataillard, M., Namer, I., Tatu, L., Wolff, V., Velizarova, R., Hacquard, A., Killic-Huck, U., Bourgin, P. Tags: Sleep: Restless Legs and REM Disorders Source Type: research

Correlation of Transcranial Doppler Breath Holding Test and Acetazolamide SPECT Scan for Anterior Circulation Steno-Occlusive Disease (P6.019)
Conclusions: There was a modest correlation between TCD-R and acetazolamide SPECT scan for anterior circulation steno-occlusive disease in our patient cohort. TCD-R demonstrated higher sensitivity for the detection of poor cerebrovascular reserve than acetazolamide SPECT. Further studies are needed to determine which study is more useful in the management of this high-risk population. Disclosure: Dr. Parikh has nothing to disclose. Dr. Cerejo has nothing to disclose. Dr. Raber has nothing to disclose. Dr. Thompson has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Katzan has received personal compensation f...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parikh, P., Cerejo, R., Raber, L., Thompson, N., Uchino, K., Katzan, I. Tags: Ischemic Stroke Diagnosis Source Type: research

Acute prolonged motor aura resembling ischemic stroke after COVID − 19 vaccination (CoronaVac): the first case report
In this study, we present the first case of stroke mimic after CoronaVac vaccination. After negative imaging studies had been performed repeatedly, we reach a conclusion that stroke is unlikely to be the cause. Presumably, this phenomenon could possibly have abnormal functional imaging study. Therefore, we believed that it might be due to cortical spreading depression, like migraine aura, which we had conducted a literature review.
Source: The Journal of Headache and Pain - August 12, 2021 Category: Neurology Source Type: research

Predictors of Development of Atrial Fibrillation in Patients With Embolic Stroke Of Undetermined Source: An Analysis of the RE-SPECT ESUS Trial
Conclusions: Besides age as the most important variable, several other factors, including hypertension, higher body mass index, and lack of diabetes, are independent predictors of AF after ESUS. When baseline NT-proBNP was available, only older age and elevation of this biomarker were predictive of subsequent AF. Understanding who is at higher risk of developing AF will assist in identifying patients who may benefit from more intense, long-term cardiac monitoring.PMID:34649459 | DOI:10.1161/CIRCULATIONAHA.121.055176
Source: Circulation - October 15, 2021 Category: Cardiology Authors: Maria Cecilia Bahit Ralph L Sacco J Donald Easton Juliane Meyerhoff Lisa Cronin Eva Kleine Claudia Grauer Martina Brueckmann Hans-Christoph Diener Renato D Lopes Michael Brainin Philippe Lyrer Rolf Wachter Tomas Segura Christopher B Granger Source Type: research

Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS
Abstract: Hypoperfusion on single-photon emission computed tomography (SPECT) of the stroke-like lesion (SLL) at the hyperacute stage of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) is considered to be a supportive evidence of the mitochondrial angiopathy theory. Our objectives were to examine whether other neuroimages, especially transcranial color-coded sonography (TCCS), done at the hyperacute stage of stroke-like episode (SLE) is consistent with hypoperfusion of the SLL. We reviewed the magnetic resonance imaging (MRI), SPECT, cerebral angiography, and TCCS of a patient with MELAS ...
Source: Brain and Development - April 20, 2012 Category: Neurology Authors: Hsu-Ling Yeh, Yen-Kung Chen, Wei-Hung Chen, Han-Cheng Wang, Hou-Chang Chiu, Li-Ming Lien, Yau-Huei Wei Tags: Original articles Source Type: research

Pathological generosity: An atypical impulse control disorder after a left subcortical stroke.
We report on a case of pathological generosity secondary to a left lenticulocapsular stroke with hypoperfusion of several anatomically intact cortical areas. A 49-year-old man developed excessive and persistent generosity as he recovered from a left lenticulocapsular hematoma. His symptoms resembled an impulse control disorder. (99m)Tc-HMPAO SPECT demonstrated hypoperfusion mostly in the ipsilateral striatum, dorsolateral, and orbitofrontal cortex. This case study adds pathological generosity to the range of behavioral changes that may result from discrete unilateral lesions of the lenticular nucleus and nearby pathways. I...
Source: Neurocase - August 20, 2013 Category: Neurology Authors: Ferreira-Garcia R, Fontenelle LF, Moll J, de Oliveira-Souza R Tags: Neurocase Source Type: research

Brain perfusion and upper limb motor function: A pilot study on the correlation between evolution of asymmetry in cerebral blood flow and improvement in Fugl–Meyer Assessment score after rTMS in chronic post-stroke patients
Conclusion Changes in AI less than zero reflect improved perfusion, suggesting that upper limb motor function improvement in post-stroke patients reflects evolution of brain perfusion in the superior and middle frontal areas.
Source: Journal of Neuroradiology - October 12, 2014 Category: Radiology Source Type: research

Super-early images of brain perfusion SPECT using 123 I-IMP for the assessment of hyperperfusion in stroke patients
ConclusionsThe addition of super-early imaging to the conventional early imaging aids assessment of postischemic hyperperfusion by123I-IMP brain perfusion SPECT and may contribute to management of stroke patients in the era of reperfusion therapy.
Source: Annals of Nuclear Medicine - September 1, 2018 Category: Nuclear Medicine Source Type: research

Improved language function for post-stroke aphasia in the long term following repeated repetitive transcranial magnetic stimulation and intensive speech-language-hearing therapy: a case report
ConclusionsThe findings of the study indicate that the repeated use of repetitive transcranial magnetic stimulation and intensive speech-language-hearing therapy may be effective in improving and preserving language function and increasing cerebral blood flow for aphasia following stroke.
Source: Journal of Medical Case Reports - July 8, 2023 Category: General Medicine Source Type: research

Posterior Fossa Syndrome After Cerebellar Stroke.
We report longitudinal clinical, neurocognitive and neuroradiological findings in a 71-year-old right-handed patient who developed PFS following a right cerebellar haemorrhage that was not surgically evacuated. During follow-up, functional neuroimaging was conducted by means of quantified Tc-99m-ECD SPECT studies. After a 10-day period of akinetic mutism, the clinical picture developed into cerebellar cognitive affective syndrome (CCAS) with reversion to a previously learnt accent, consistent with neurogenic foreign accent syndrome (FAS). No psychometric evidence for dementia was found. Quantified Tc-99m-ECD SPECT studies ...
Source: Cerebellum - April 11, 2013 Category: Neuroscience Authors: Mariën P, Verslegers L, Moens M, Dua G, Herregods P, Verhoeven J Tags: Cerebellum Source Type: research

123I-Iomazenil Single Photon Emission Computed Tomography Visualizes Recovery of Neuronal Integrity by Bone Marrow Stromal Cell Therapy in Rat Infarct Brain Basic Sciences
Conclusions— The present findings strongly suggest that the BMSCs may enhance functional recovery by improving the neuronal integrity in the peri-infarct area, when directly transplanted into the infarct brain at clinically relevant timing. 123I-IMZ single photon emission computed tomography may be a promising modality to scientifically prove the beneficial effects of BMSC transplantation on the host brain in clinical situation.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Saito, H., Magota, K., Zhao, S., Kubo, N., Kuge, Y., Shichinohe, H., Houkin, K., Tamaki, N., Kuroda, S. Tags: Animal models of human disease, Acute Cerebral Infarction, PET and SPECT, Other Stroke Treatment - Medical, Other Stroke Treatment - Surgical Basic Sciences Source Type: research

Combined 18F-FDG PET-CT and DCE-MRI to Assess Inflammation and Microvascularization in Atherosclerotic Plaques Brief Reports
Conclusions— There is a weak but significant positive correlation between inflammation on positron emission tomography/computed tomography and neovascularization as assessed with dynamic contrast–enhanced-MRI. Future studies should investigate which imaging modality has the highest predictive value for recurrent stroke, as these are not interchangeable. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00451529.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Truijman, M. T. B., Kwee, R. M., van Hoof, R. H. M., Hermeling, E., van Oostenbrugge, R. J., Mess, W. H., Backes, W. H., Daemen, M. J., Bucerius, J., Wildberger, J. E., Kooi, M. E. Tags: Imaging, Carotid Stenosis, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT Brief Reports Source Type: research