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Nutrition: Potassium
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Total 378 results found since Jan 2013.
Association of KATP Gene Polymorphisms with Dyslipidemia and Ischemic Stroke Risks Among Hypertensive Patients in South China
This study investigates the potential association between KATP polymorphisms and hypertension (HTN), dyslipidemia, and consequently ischemic stroke (IS). Nine hundred and fourteen (914) patients genotyped for KATP polymorphisms (rs2285676, rs1799858, rs4148671, rs61928479, and rs141294036) were analyzed. KATP rs141294036 (CC, adjusted OR = 1.59, 95%CI: 1.17–2.14,P = 0.003) was related to higher HTN risk. Meanwhile, rs2285676 (AA + GA, adjusted OR = 1.53, 95%CI: 1.08–2.19,P = 0.018) was associated with increased triglyceride level (≥ 1.7 mmol/L). rs2285676 (AA + GA, adjusted OR = 1.80, 95% CI: 1.24–...
Source: Journal of Molecular Neuroscience - January 5, 2021 Category: Neuroscience Source Type: research
Potassium-rich foods cut stroke, death risks among older women
Older women who eat foods with higher amounts of potassium may be at lower risk of stroke and death than women who consume less potassium-rich foods. The health benefits from potassium-rich foods are greater among older women who do not have high blood pressure. Most older American women do not eat the recommended amounts of potassium from foods.
Source: ScienceDaily Headlines - September 4, 2014 Category: Science Source Type: news
The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke
Reactive astrogliosis is one of the significantly pathological features in ischemic stroke accompanied with changes in gene expression, morphology, and proliferation. KCa3.1 was involved in TGF- β-induced astro...
Source: Journal of Neuroinflammation - October 16, 2017 Category: Neurology Authors: Mengni Yi, Tianjiao Wei, Yanxia Wang, Qin Lu, Gaoxian Chen, Xiaoling Gao, Herbert M. Geller, Hongzhuan Chen and Zhihua Yu Tags: Research Source Type: research
Prognostic Impact of Mild Hypokalemia in Terms of Death and Stroke in the General Population —A Prospective Population Study
Potassium supplementation reduces the risk of cardiovascular mortality and stroke in population studies; however, the prognostic impact of mild hypokalemia in the general population has not been thoroughly investigated. We aimed to investigate associations between mild hypokalemia and endpoints in the general population.
Source: The American Journal of Medicine - October 9, 2017 Category: General Medicine Authors: Nick Mattsson, Olav Wendelboe Nielsen, Linda Johnson, Eva Prescott, Peter Schnohr, Gorm Boje Jensen, Lars K øber, Ahmad Sajadieh Tags: Clinical Research Study Source Type: research
Response by Johnson and Soderholm to Letter Regarding Article, “Serum Potassium Is Positively Associated With Stroke and Mortality in the Large, Population-Based Malmo Preventive Proȷect Cohort” Letter to the Editor
Source: Stroke - December 22, 2017 Category: Neurology Authors: Linda S. Johnson, Martin Soderholm Tags: Cardiovascular Disease, Epidemiology Letters to the Editor Source Type: research
Molecules, Vol. 26, Pages 6124: A Novel Phenylpyrrolidine Derivative: Synthesis and Effect on Cognitive Functions in Rats with Experimental Ishemic Stroke
Vladimir P. Chekhonin
Sophia S. Borisevich
Maxim A. Gureev
Anastasia D. Shagina
Nina M. Kiseleva
Vadim V. Negrebetsky
Yuri I. Baukov
We performed an in silico, in vitro, and in vivo assessment of a potassium 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl) acetamido]ethanesulfonate (compound 1) as a potential prodrug for cognitive function improvement in ischemic brain injury. Using in silico methods, we predicted the pharmacological efficacy and possible safety in rat models. In addition, in silico data showed neuroprotective features of compound 1, which were further supported by in vitro experiments in a glutamate e...
Source: Molecules - October 11, 2021 Category: Chemistry Authors: Denis A. Borozdenko Aiarpi A. Ezdoglian Tatiana A. Shmigol Darya I. Gonchar Dmitri N. Lyakhmun Dmitri V. Tarasenko Yaroslav V. Golubev Elvira A. Cherkashova Daria D. Namestnikova Ilya L. Gubskiy Alexey A. Lagunin Leonid V. Gubsky Vladimir P. Chekhonin Sop Tags: Article Source Type: research
The bean that could lower blood pressure and reduce stroke risk - high in potassium
One study showed that a potassium-rich diet could not only reduce blood pressure but lower the risk of stroke by 24 percent.
Source: Daily Express - Health - February 6, 2023 Category: Consumer Health News Source Type: news
A Novel Variant in Non-coding Region of GJB1 Is Associated With X-Linked Charcot-Marie-Tooth Disease Type 1 and Transient CNS Symptoms
Conclusion
A novel GJB1 variant of c.-170T>G in non-coding region was found in this big Chinese CMTX1 pedigree. This is the first report of variant in non-coding DNA sequence associated with transient CNS symptoms. Thyroid malfunction may contribute to the CNS symptoms in this case.
Ethics Statement
This study has been reviewed and approved by the Ethics Committee of the China-Japan Union Hospital of Jilin University. Each member of the family provided written informed consent to the participation in the study, the genetic test, and authorized to publish the study including the photos in accordance with the Decl...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research
Seaweed Intake and Risk of Cardiovascular Disease: The Circulatory Risk in Communities Study (CIRCS).
CONCLUSIONS: We found an inverse association between seaweed intake and risk of total stroke, especially that from cerebral infarction, among Japanese men.
PMID: 33597328 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 21, 2021 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Urinary potassium excretion and risk of cardiovascular events.
CONCLUSION: In this cohort with oversampling of subjects with albuminuria at baseline, urinary potassium excretion was not independently associated with a lower risk of cardiovascular events.
PMID: 26984482 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - March 16, 2016 Category: Nutrition Authors: Kieneker LM, Gansevoort RT, de Boer RA, Brouwers FP, Feskens EJ, Geleijnse JM, Navis G, Bakker SJ, Joosten MM, PREVEND Study Group Tags: Am J Clin Nutr Source Type: research
Urinary potassium excretion and risk of cardiovascular events Cardiovascular disease risk
Conclusion: In this cohort with oversampling of subjects with albuminuria at baseline, urinary potassium excretion was not independently associated with a lower risk of cardiovascular events.
Source: American Journal of Clinical Nutrition - May 1, 2016 Category: Nutrition Authors: Kieneker, L. M., Gansevoort, R. T., de Boer, R. A., Brouwers, F. P., Feskens, E. J., Geleijnse, J. M., Navis, G., Bakker, S. J., Joosten, M. M., for The PREVEND Study Group Tags: Cardiovascular disease risk Source Type: research
Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion
This study demonstrates the importance of including risk factors in experimental stroke research.Pharmacology 2018;101:120 –132
Source: Pharmacology - November 30, 2017 Category: Drugs & Pharmacology Source Type: research
Role of TREK-1 in Health and Disease, Focus on the Central Nervous System
Conclusion and Perspectives
Since their cloning 20 years ago, the physiological importance of TREK-1 channels has continued to grow (Figure 3). Today, TREK-1 channels have been shown to be important and their presence is essential in a number of physiopathological processes. Their involvement in these different processes demonstrate the necessity to design pharmacological modulators, activators or inhibitors, of these channels to correct any TREK-1-related dysfunctions.
Despites a number of studies and many molecule screenings, only few putative new drugs were identified. The activators belonging to the ML and BL series ...
Source: Frontiers in Pharmacology - April 10, 2019 Category: Drugs & Pharmacology Source Type: research
BIIB093 (intravenous glibenclamide) for the prevention of severe cerebral edema
CONCLUSION: Studies analyzing the GAMES-Pilot and GAMES-PR trials suggest that glibenclamide has a moderate, however, measurable effect on intermediate biomarkers and clinical endpoints. Meaningful conclusions are limited by the small sample size of patients studied.PMID:33767884 | PMC:PMC7982107 | DOI:10.25259/SNI_933_2020
Source: Surgical Neurology International - March 26, 2021 Category: Neurosurgery Authors: Daniel W Griepp Jason Lee Christina M Moawad Cyrus Davati Juliana Runnels Brian Fiani Source Type: research
