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Total 459 results found since Jan 2013.

Organizing stroke systems in the field for patients with suspected large vessel occlusion acute stroke.
Authors: Almekhlafi MA, Holodinsky JK, Hill MD, Kamal N, Goyal M Abstract INTRODUCTION: The dawn of endovascular stroke therapy has reshaped stroke care. Eligible patients need to be rushed to capable centers for intervention. This may entail bypassing closer hospitals that could confirm the diagnosis, administer thrombolytic therapy, then transfer patients for intervention. This has created a set of challenges: identifying endovascular candidates in the field, determining the best transport destination, and getting patients there quickly. Areas covered: This review provides a context for these emerging challenges....
Source: Expert Review of Cardiovascular Therapy - November 20, 2018 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research

Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection
Conclusion:Achieving viral suppression may reduce ischemic stroke risk, including risk of atherosclerotic strokes, in HIV-infected individuals.
Source: AIDS - October 31, 2014 Category: Infectious Diseases Tags: Clinical Science: Concise Communications Source Type: research

Development of a patient‐centred, patient‐reported outcome measure (PROM) for post‐stroke cognitive rehabilitation: qualitative interviews with stroke survivors to inform design and content
ConclusionsThe results support the development of a PROM specifically designed to address the impact of cognitive problems. It should: include items addressing a comprehensive range of cognitive skills; ask questions about mood, self‐identity and social participation; use accessible wording that respondents understand and endorse; measure impact rather than frequency; and explore perceived impact on carers.
Source: Health Expectations - December 5, 2014 Category: Health Management Authors: Emma L. Patchick, Maria Horne, Kate Woodward‐Nutt, Andy Vail, Audrey Bowen Tags: Original Article Source Type: research

Rehab-let: touchscreen tablet for self-training impaired dexterity post stroke: study protocol for a pilot randomized controlled trial
DiscussionThe outcomes of this study will inform the design of a fully powered randomized controlled trial to evaluate the effectiveness of Rehab-let. If found to be effective, Rehab-let can be used during subacute rehabilitation to increase treatment intensity and improve dexterity. Potentially, Rehab-let can also be used after discharge and might be ideal for individuals with mild stroke who are often not referred to formal rehabilitation.Trial RegistrationCurrent Controlled Trials NCT02136433 registered on 17 September 2014.
Source: BioMed Central - June 17, 2015 Category: Journals (General) Authors: Debbie RandGabi ZeiligRachel Kizony Source Type: research

Ethics and Bias in Clinical Trial Enrollment in Stroke
AbstractPurpose of ReviewTo familiarize the reader with ethical concerns and potential scientific bias in management and conduction of clinical stroke trials.Recent FindingsThe goal of clinical trials in stroke is to find effective interventions for stroke prevention, acute treatment, and rehabilitation and recovery. Acute trials must be designed in the context of the time-sensitivity of revascularization therapies. Standard ethical constraints apply. However, informed consent is hindered by tight time windows for reperfusion therapy and frequent cognitive impairment in patients. These might be mitigated by using visual de...
Source: Current Cardiology Reports - April 21, 2019 Category: Cardiology Source Type: research

End-of-Life Care Decision-Making in Stroke
Stroke is one of the leading causes of death and long-term disability in the United States. Though advances in interventions have improved patient survival after stroke, prognostication of long-term functional outcomes remains challenging, thereby complicating discussions of treatment goals. Stroke patients who require intensive care unit care often do not have the capacity themselves to participate in decision making processes, a fact that further complicates potential end-of-life care discussions after the immediate post-stroke period. Establishing clear, consistent communication with surrogates through shared decision-m...
Source: Frontiers in Neurology - September 28, 2021 Category: Neurology Source Type: research

Assessing the characteristics and diagnostic value of plaques for patients with acute stroke using high-resolution magnetic resonance imaging
CONCLUSIONS: A larger plaque area and smaller LA in the stenotic MCA, and obvious plaque enhancement might indicate that a patient is prone to acute stroke.PMID:35111645 | PMC:PMC8739121 | DOI:10.21037/qims-21-531
Source: Atherosclerosis - February 3, 2022 Category: Cardiology Authors: Danfeng Zhang Mi Wang Lili Wu Ying Zhao Siyu Wang Xindao Yin Xinying Wu Source Type: research

IJERPH, Vol. 19, Pages 16925: Effect of Treadmill Training with Visual Biofeedback on Selected Gait Parameters in Subacute Hemiparetic Stroke Patients
Conclusions: The treadmill with visual biofeedback as conventional gait training has resulted in a significant improvement in parameters such as step length, walking speed, static balance, and a reduction in the use of locomotion aids. However, the achieved improvement in gait parameters is still not in line with the physiological norm.
Source: International Journal of Environmental Research and Public Health - December 16, 2022 Category: Environmental Health Authors: Katarzyna Ka źmierczak Agnieszka Ware ńczak-Pawlicka Margaret Miedzyblocki Przemys ław Lisiński Tags: Article Source Type: research

Use of aspirin and statins for the primary prevention of myocardial infarction and stroke in patients with human immunodeficiency virus infection
This retrospective, cross-sectional study evaluated whether HIV-infected patients received aspirin and statins for the primary prevention of myocardial infarction and stroke. Among the 258 patients included, 50.4% (n = 130/258) of the patients had a high risk of myocardial infarction and 14% (n = 36/258) of stroke. Overall, 43.1% (n = 56/130) and 50% (n = 18/36) of the patients were prescribed aspirin for the primary prevention of myocardial infarction and stroke, respectively. Among the patients who required statin therapy, 42.5% (n = 34/80) and 37.1% (n = 13/35) of patients received it for the primary prevention of myoca...
Source: International Journal of STD and AIDS - April 6, 2016 Category: Global & Universal Authors: Park, T. E., Yusuff, J., Sharma, R. Tags: Original research articles Source Type: research

Factors influencing the response to high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke.
CONCLUSION: Our findings suggest that high-frequency rTMS interventions aimed at improving upper extremity motor function in patients with subacute stroke with moderate to severe motor involvement should be individually tailored according to functional CST status and BDNF genotype. PMID: 27372515 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - July 5, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Factors influencing the response to  high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke.
CONCLUSION: Our findings suggest that high-frequency rTMS interventions aimed at improving upper extremity motor function in patients with subacute stroke with moderate to severe motor involvement should be individually tailored according to functional CST status and BDNF genotype. PMID: 27372515 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - July 21, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Chapter 15 HIV infection and stroke
Publication date: 2018 Source:Handbook of Clinical Neurology, Volume 152 Author(s): Laura Benjamin, Saye Khoo The landscape of human immunodeficiency virus (HIV) infection is changing with the increasing coverage of antiretroviral therapy (ART). Patients are living longer but continually exposed to a virologically suppressed HIV infection. This has resulted in a decrease in acquired immune deficiency syndrome (AIDS)-related complications such as opportunistic infections, and an increase in non-AIDS complications such as stroke. In this era, stroke is perhaps the most important neurologic complication of HIV infection. Fur...
Source: Handbook of Clinical Neurology - March 29, 2018 Category: Neurology Source Type: research

Managing of Lower Urinary Tract Dysfunction Following Stroke
AbstractPurpose of ReviewThis comprehensive up-to-date review will synthesise relevant available literature on the topic of post-stroke lower urinary tract dysfunction (LUTD). Topics include epidemiology of LUTD, LUTD as a prognostic indicator for stroke recovery, urinary incontinence and retention, correlations between brain lesion localisation and LUTD, causes of LUTD, medical complications due to LUTD, diagnostics and contemporary management of LUTD in stroke patients.Recent FindingsLUTD frequently occurs after a stroke and is associated with poor overall functional outcome, increased institutionalisation and mortality ...
Source: Current Bladder Dysfunction Reports - June 11, 2018 Category: Urology & Nephrology Source Type: research

The relationship between Home-time, quality of life and costs after ischemic stroke: the impact of the need for mobility aids, home and car modifications on Home-time.
CONCLUSIONS: Home-time is a stroke outcome associated with disease severity, healthcare costs and patient wellbeing. Streamlining the discharge process for those requiring extra material support may lead to cost savings and higher quality-of-life. Implications for rehabilitation Delays in discharge from the acute hospital or rehabilitation facility are incurred when patients need extra material support in order to return home. Staff from the discharging facility should assist families by giving timely information on the availability and the cost of wheel chairs and walkers; and explaining and planning the need of a stair l...
Source: Disability and Rehabilitation - October 2, 2018 Category: Rehabilitation Authors: Dewilde S, Annemans L, Lloyd A, Peeters A, Hemelsoet D, Vandermeeren Y, Desfontaines P, Brouns R, Vanhooren G, Cras P, Michielsens B, Redondo P, Thijs V Tags: Disabil Rehabil Source Type: research