Corrigendum
(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - November 17, 2016 Category: Global & Universal Tags: Corrigendum Source Type: research

Lymphogranuloma venereum presenting with erythema nodosum
We present the case of a 30-year-old HIV-negative man with inguinal type lymphogranuloma venereum accompanied by erythema nodosum. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Borsje, A., van der Reijden, W., Soetekouw, R. Tags: Case reports Source Type: research

First case of pancreas transplant alone in a patient with diabetes and HIV infection
We describe the use of a standard immunosuppression regimen in combination with effective antiretroviral control using a stable highly active antiretroviral therapy regimen with minimal interaction with immunosuppressants. We describe what is, to our knowledge, the first case of pancreas transplantation alone performed for this particularly challenging group, resulting in complete resolution of hypoglycaemic symptoms. We suggest that this group of patients should receive optimal diabetes management, including access to transplantation where appropriate, and demonstrate that pancreas transplantation alone is feasible for pe...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Mittal, S., Choudhary, P., Callaghan, C., Hilton, R., Drage, M. Tags: Case reports Source Type: research

An unusual case of underlying rilpivirine resistance in an antiretroviral-naïve man with AIDS
We report an antiretroviral treatment (ART)-naïve patient with acquired immunodeficiency syndrome (AIDS) (CD4 cell count 20 cells/mm3, viral load 8439 copies/mL), who was infected with HIV-1 sub-type B virus containing a reverse transcriptase mutation, E138A, associated with rilpivirine resistance. Subsequently, he was initiated on a single tablet ART regimen containing an integrase inhibitor and developed immune reconstitution inflammatory syndrome (IRIS), presenting as Mycobacterium avium cervical adenitis. The patient went on to develop rifamycin-induced neutropenia during treatment of his opportunistic infectio...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Skalweit, M. J. Tags: Case reports Source Type: research

Diffuse HIV-associated seborrheic dermatitis - a case series
Seborrheic dermatitis (SD) is reported to have distinct clinical and histologic presentations in patients with HIV infection. Here we present 20 cases to further define some of these unique characteristics. Common features include erythematous, scaly papules, and plaques involving areas beyond the typical seborrheic distribution; thick, greasy scale on the scalp; and an increased frequency of erythroderma. Histologically, there is widespread parakeratosis, spongiosis, and necrotic keratinocytes. Treatment is often difficult, requiring prolonged use of oral and topical antifungals and corticosteroids as well as antibiotics ...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Forrestel, A. K., Kovarik, C. L., Mosam, A., Gupta, D., Maurer, T. A., Micheletti, R. G. Tags: Case reports Source Type: research

Missed opportunities in the prevention of mother-to-child transmission of HIV infection: experience from a national programme in Nigeria
An analysis of validated National Prevention of Mother-to-Child Transmission (PMTCT) data from 2008 to 2014 showed that Nigeria has recorded steady progress. However, to achieve elimination of mother-to-child transmission of HIV, service scale-up and active testing of pregnant women are required, as a large number of HIV-infected women in Nigeria are not aware of their HIV status. Focusing on efforts that will improve access and uptake of antenatal care/PMTCT services will significantly reduce new infant HIV infection. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Adeyinka, D. A., Agogo, E. A., Ozigbu, C. E., Aboje, S., Anyaike, C., Asadu, E. C., Odoh, D., Ganiyu, J. Tags: Audit report Source Type: research

Clinical diagnosis of syphilis: a ten-year retrospective analysis in a South Australian urban sexual health clinic
National notifications for infectious syphilis in Australia have increased in recent years. Outside of sexual health clinics, junior clinicians seldom encounter this disease in its infectious stage (primary, secondary and early latent). With such a variable clinical presentation, textbook teaching is no substitute for real-life experience. The importance of accurate classification and staging of disease is relevant to the risk of transmission and determines treatment duration. In this article, the authors review the clinical presentation of syphilis over ten years in an urban sexual health clinic with a focus on the clinic...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Forrest, C., Ward, A. Tags: Original research articles Source Type: research

The effect of introducing routine self-taken extra-genital swabs in a genitourinary medicine clinic cohort: a before and after study
Starting July 2013, all patients attending a sexual health clinic who reported risk of extra-genital infection were offered self-taken extra-genital swabs. The study aim was to assess the detection rate of extra-genital infection since self-taken swabs were introduced. We compared patients diagnosed with chlamydia and gonorrhoea in six-month periods before (February–July 2012) and after (February–July 2014) the introduction of self-taken extra-genital swabs. There were 408 (98 gonorrhoea, 310 chlamydia) detected infections in the 2012 period and 404 (121 gonorrhoea, 283 chlamydia) in 2014. The rate of extra-gen...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Nyatsanza, F., Trivedy, A., Brook, G. Tags: Original research articles Source Type: research

Significant benefit of a targeted HIV testing module on medical students knowledge and confidence
The objective was to evaluate the efficacy of a HIV targeted-testing teaching session in improving knowledge and confidence at a London medical school. A survey assessing knowledge of HIV testing guidelines, confidence to offer testing and outcomes of targeted-testing teaching was developed and distributed to fifth year medical students. Results were compared for students who had completed GU/HIV modules (GU+) and those who had not (GU–) and chi-squared testing was performed; 100 and 119 questionnaires were returned by GU+ and GU– students (response rate of 92.6% and 97.5%), respectively. For the three knowledg...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Chong, M., Cartledge, J., Waters, L. Tags: Original research articles Source Type: research

Association of sexual risk behaviour with previous HIV testing among voluntary HIV counselling and testing clients in Kigali, Rwanda
With increased coverage of voluntary HIV counselling and testing (VCT) in Rwanda and a greater focus on repeat testing of key populations, it is important to understand whether the right clients are returning for repeat testing and if repeat testing is effective at reducing risk. We assessed the association between repeat testing and recent sexual risk behaviours among 1852 first time or repeat HIV testing clients in Kigali who had had sex, using data from a cross-sectional survey. Repeat testing was associated with being female, older and type of occupation. Multivariable analyses indicate that individuals who tested for ...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Stalter, R., Chen, M., Uwizeye, G., Mutunge, E., Ahayo, A., Mugwaneza, P., Shumbusho, F., Wesson, J. Tags: Original research articles Source Type: research

A comparison of recreational drug use amongst sexual health clinic users in London with existing prevalence data
The objective was to give an overview of self-reported recreational drug use amongst attendees of sexual health clinics in London and compare this to existing datasets. Between December 2013 and March 2014, attendees of two sexual health clinics in London were surveyed. Data collected were: sexual history, smoking and alcohol and recreational drug use. Data were analysed using SPSS (version 21). A total of 1472 respondents were included; 778 (52.9%) men, 676 (45.9%) women and 3 (0.2%) transgender (15 [1.0%] did not answer). Mean age was 30.6 ± 9.0 years. A total of 339 (43.6%) men were men who have sex with men (MSM...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Thurtle, N., Dargan, P. I., Hunter, L. J., Lovett, C., White, J. A., Wood, D. M. Tags: Original research articles Source Type: research

Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection
Recent data suggest that azithromycin may not be as effective as doxycycline in eradication of genital chlamydial infection. The aim of this study was to compare the eradication rate of pharyngeal Chlamydia trachomatis infection after treatment with azithromycin 1 g stat with that of doxycycline 100 mg twice a day for seven days. A prospective open-label observational study was conducted on patients with pharyngeal Chlamydia trachomatis diagnosed at Whittall Street Clinic, University Hospitals Birmingham, Birmingham, UK, between July 2012 and July 2013. We confirmed eradication of pharyngeal Chlamydia trachomatis with a ne...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Manavi, K., Hettiarachchi, N., Hodson, J. Tags: Original research articles Source Type: research

Lubricant use and condom use during anal sex in men who have sex with men in Tanzania
We describe use, knowledge, and access to lubricants in Dar es Salaam and Tanga, Tanzania. Data were collected in 2012 and 2013 from a cross-sectional survey of 200 MSM in Dar es Salaam and 100 MSM in Tanga, Tanzania. The most common reason for not using condoms was dislike of condoms. Two-thirds of the men reported always using a lubricant for anal sex. Results showed that: fewer men who have sex with both men and women (MSMW) know about lubricants; more MSM look for, have difficulty finding, and find lubricants to be expensive; and MSM use lubricants to facilitate penetration. MSMW commonly receive their lubricants from ...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Romijnders, K. A., Nyoni, J. E., Ross, M. W., McCurdy, S. A., Mbwambo, J., Kok, G., Crutzen, R. Tags: Original research articles Source Type: research

Prevalent bacterial vaginosis infection - a risk factor for incident sexually transmitted infections in women in Durban, South Africa
The association between bacterial vaginosis (BV) and incident sexually transmitted infections (STIs) in a cohort of high-risk women from Durban, South Africa was investigated in this study. We undertook a secondary analysis of the Methods for Improving Reproductive Health in Africa trial that assessed effectiveness of the latex diaphragm and lubricant gel on HIV prevention among women. During study visits, urine specimens were collected for testing for Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis. The presence of BV was based on vaginal pH and wet mount test assessments. The association between BV...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Abbai, N. S., Reddy, T., Ramjee, G. Tags: Original research articles Source Type: research

Multiplex PCR testing for nine different sexually transmitted infections
Current sexually transmitted infection (STI) testing is not optimal due to delays in reporting or missed diagnoses due to a lack of comprehensive testing. The FilmArray® (BioFire Diagnostics, LLC, Salt Lake City, Utah) is a user-friendly, fully automated, multiplex PCR system that is being developed for rapid point-of-care use. A research-use-only STI panel including multiple PCR primer sets for each organism was designed to detect Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, Trichomonas vaginalis, Mycoplasma genitalium, Ureaplasma urealyticum, Haemophilus ducreyi, and herpes simplex virus (HSV) ty...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Kriesel, J. D., Bhatia, A. S., Barrus, C., Vaughn, M., Gardner, J., Crisp, R. J. Tags: Original research articles Source Type: research