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Total 459 results found since Jan 2013.

Mindful Music Listening Aids Cognitive Recovery After Stroke
Mindful music listening feasible, acceptable, may be effective after stroke
Source: The Doctors Lounge - Psychiatry - May 14, 2019 Category: Psychiatry Tags: Neurology, Psychiatry, Journal, Source Type: news

Apical Lung Exam on CTA Aids COVID-19 Screen in Stroke Patients
THURSDAY, Oct. 29, 2020 -- For patients presenting with acute ischemic stroke (AIS), apical lung assessment on computed tomography angiography (CTA) may be useful as part of the screening approach for COVID-19, according to a study published online...
Source: Drugs.com - Pharma News - October 29, 2020 Category: Pharmaceuticals Source Type: news

To Decompress or Not? An Expected Utility Inspired Approach To Shared decision-making For Supratentorial Ischemic Stroke
AbstractPatients with large territorial supratentorial infarctions are at high risk of cerebral edema, increased intracranial pressure, tissue herniation and death. There is strong evidence supporting prompt decompressive craniectomy after large hemispheric ischemic stroke as a means to reduce mortality. Nevertheless, functional outcomes can vary significantly. Clinical trials have traditionally judged these outcomes by a priori dichotomization without taking into account individual patient and caregiver preferences. If these are not incorporated into shared decision-making, there are significant risks in both directions, ...
Source: Neurocritical Care - February 18, 2021 Category: Neurology Source Type: research

Incidence and risk factors of ischemic stroke and transient ischemic attack among people living with HIV: a longitudinal cohort study
AIDS Res Hum Retroviruses. 2021 Oct 29. doi: 10.1089/AID.2021.0046. Online ahead of print.ABSTRACTPeople living with HIV (PLWH) have higher ischemic cerebrovascular disease rates than HIV-negative individuals. We aimed to determine the incidence and risk factors of ischemic stroke (IS) and transient ischemic attack (TIA) among Thai PLWH. Data from adults living with HIV who were enrolled in a prospective HIV-NAT 006 cohort in Bangkok, Thailand, from 1996 to 2020 were included in the analysis. The primary endpoint was first-ever IS or TIA. Among 2020 PLWH included in the analysis, 16 (0.8%) developed first-ever IS/TIA over ...
Source: Cell Research - October 29, 2021 Category: Cytology Authors: Akarin Hiransuthikul Aurauma Chutinet Jiratchaya Sophonphan Sasiwimol Ubolyam Kiat Ruxrungtham Anchalee Avihingsanon Source Type: research

Minute Stroke Distance is a More Reproducible Measurement Than Cardiac Output in the Assessment of Fetal Ventricular Systolic Function
Echocardiographic quantification of fetal cardiac output (CO) aids clinical decision-making in the management of various cardiac and extracardiac diseases. Small variability in measuring semilunar valve dimension significantly reduces the reproducibility of the calculated CO. We propose minute stroke distance or velocity-time integral (VTI) as a more reproducible measure reflecting fetal ventricular systolic function. We hypothesized that right and left ventricular minute VTI increase predictably with estimated fetal weight (EFW) and are more reproducible than CO.
Source: Journal of the American Society of Echocardiography - August 13, 2022 Category: Cardiology Authors: Heather Y. Sun, Elif Seda Selamet Tierney, Theresa A. Tacy, Rajesh Punn Tags: Clinical Investigations Source Type: research

Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
Conclusion and Future Aspects This review summarizes available NTF expression data, compiles existing evidence on the effects of glial NTF signaling in healthy conditions and in disease models (Figure 1), and highlights the importance of this topic for future studies. The relationship between NTFs and glia is crucial for both the developing and adult brain. While some of these factors, such as NT-3 and CNTF, have highly potent effects on gliogenesis, others like BDNF and GDNF, are important for glia-mediated synapse formation. Neurotrophic factors play significant roles during neurodegenerative disorders. In many cases, ...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

Clinical round-up
HIV and stroke The association between HIV infection and coronary heart disease and haemorrhagic stroke has already been described1–3 but less is known about ischaemic stroke. Sico et al4 looked at the risk factors for ischaemic stroke in HIV+ individuals as part of the Veterans Administration Cohort Study, a study of clinical and laboratory data sets collected from 99 688 US veterans. They compared HIV+ patients with HIV– controls matched for age, sex race/ethnicity and clinical site over a 6-year period from 2003 to 2009, and after women and those with baseline cardiovascular disease (CVD) or stroke were...
Source: Sexually Transmitted Infections - January 20, 2016 Category: Sexual Medicine Authors: Herbert, S., Haddow, L. Tags: Epidemiologic studies, Drugs: infectious diseases, HIV/AIDS, Contraception, Drugs: obstetrics and gynaecology, Reproductive medicine, HIV / AIDS, Gonorrhoea, HIV infections, Health education, Smoking Clinical round-up Source Type: research

The impact of STRENGTH on the expected and actual transition to home experience.
Conclusions: People with stroke described the therapy they received in both the hospital and home as beneficial. The results support the addition of the home-based inpatient program, STRENGTH, to the current rehabilitation system, as it appeared to realign the expectations of people with stroke and better prepare them for their discharge home. Implications for Rehabilitation STRENGTH aids clinicians to identify difficulties in the home environment for people with stroke. STRENGTH improves the confidence of people with stroke while they transition home. Further research is warranted for psychological interventions that prep...
Source: Disability and Rehabilitation - March 27, 2014 Category: Rehabilitation Authors: Gustafsson LA, Hodson TJ, Fleming JM, Hoyle MF Tags: Disabil Rehabil Source Type: research

A risk assessment tool incorporating new biomarkers for cardiovascular events in acute coronary syndromes: the Organization to Assess Strategies in Ischemic Syndromes (OASIS) risk score
Conclusions The addition of NT-proBNP and hemoglobin A1C to 5 standard variables creates a 7-variable risk score that improves prediction of cardiovascular events at 1 year and aids in risk-based selection of NSTEACS patients for dual antiplatelet therapy. Teaser Several new biomarkers improve risk stratification in non-ST-segment elevation ACS, however they are not integrated into risk prediction tools. A risk score to predict CV death/MI/stroke was developed by incorporating new biomarkers with standard variables. The addition of NT-proBNP and hemoglobin A1C to 5 standard variables (age, prior MI/stroke, sex, ST-segment ...
Source: Canadian Journal of Cardiology - February 3, 2016 Category: Cardiology Source Type: research

Changing clinical patterns and increasing prevalence in CADASIL
ConclusionsCADASIL prevalence is at least 4.6 per 100,000 adults. Median age of first stroke may be older than previously thought. Clinicians should consider CADASIL in the differential diagnosis even in older patients with stroke.
Source: Acta Neurologica Scandinavica - April 1, 2014 Category: Neurology Authors: F. C. Moreton, S. S. M. Razvi, R. Davidson, K. W. Muir Tags: Original Article Source Type: research

Cerebrovascular Disease and HIV in Singapore: A Single-Centre Study (P1.325)
Conclusions: Prevalence of CVS risk factors was significant in our population. Stroke in HIV patients may result from other disease mechanisms and carries significant mortality and morbidity. Fever at presentation suggests an infective etiology.Disclosure: Dr. Gan holds stock and/or stock options in a company which sponsored research in which Dr. Gan was involved as an investigator. Dr. Saini has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ng has nothing to disclose. Dr. Tan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gan, E., Saini, M., Lee, C.-C., Ng, O.-T., Tan, K. Tags: HIV/AIDS Source Type: research

Cardiovascular outcomes among HIV-infected veterans receiving atazanavir
Conclusion: Among treatment-naive HIV-infected patients in the Veterans Health Administration initiating ATV-containing regimens, risk of both MI and stroke were significantly lower than in those initiating regimens containing other protease inhibitors, NNRTIs, or INSTIs.
Source: AIDS - September 15, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

GSE173713 RNA Sequencing of WT Aged Vehicle vs. HPBCD Infarcts
Contributors : Danielle A Becktel ; Kristian P DoyleSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe systematically characterized the transcriptomes of stroke infarcts in vehicle- and HP βCD-treated aged (18-month-old) mice by performing bulk RNA-Seq on infarcted brain tissue collected 7 weeks after distal middle cerebral artery occlusion + hypoxia (DH) stroke. The DE analysis revealed 991 upregulated genes and 1,876 downregulated genes. HPβCD treatment upregulated intracellular c holesterol transporters, lipoproteins, and lipoprotein receptors, such as Npc1, Npc2, Apoe, Trem2, Ab...
Source: GEO: Gene Expression Omnibus - May 3, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research