Association of Machine Learning –Derived Phenogroupings of Echocardiographic Variables with Heart Failure in Stable Coronary Artery Disease: The Heart and Soul Study
Many individual echocardiographic variables have been associated with heart failure (HF) in patients with stable coronary artery disease (CAD), but their combined utility for prediction has not been well studied. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 13, 2020 Category: Cardiology Authors: Rakesh K. Mishra, Geoffrey H. Tison, Qizhi Fang, Rebecca Scherzer, Mary A. Whooley, Nelson B. Schiller Source Type: research

Can Aortic Regurgitation Evolve into Aortic Stenosis? New Insights on Mixed Aortic Valve Disease
Patients with combined moderate aortic stenosis (AS) and moderate regurgitation (AR) are categorized as having mixed aortic valve disease (MAVD), and most progress to a predominant lesion, most commonly severe AS1; however, a few may progress to predominant AR. It is thus probable that AS and AR could evolve together from mild to moderate and then one lesion may progress further to become predominant; that lesion usually is AS. For patients who initially present with at least moderate AS and mild  AR or less, the path is usually relentless, irreversible progression to severe AS. (Source: Journal of the American Societ...
Source: Journal of the American Society of Echocardiography - January 13, 2020 Category: Cardiology Authors: Li-Tan Yang, Patricia A. Pellikka, Maurice Enriquez-Sarano, Sushil A. Luis, Ratnasari Padang, Bruce K. Daniels, Christopher G. Scott, Hector I. Michelena Tags: Letters to the Editor Source Type: research

Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia
The clinical utility of echocardiography for the diagnosis of pulmonary vascular disease (PVD) in former preterm infants with bronchopulmonary dysplasia (BPD) is not established. Elevated pulmonary vascular resistance (PVR) rather than pulmonary artery pressure (PAP) is the hallmark of PVD. We evaluated the utility of echocardiography in infants with BPD in diagnosing pulmonary hypertension and PVD (PVR>3 Wood units  × m2) assessed by cardiac catheterization. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 13, 2020 Category: Cardiology Authors: Hythem Nawaytou, Martina A. Steurer, Yili Zhao, Elyssa Guslits, David Teitel, Jeffrey R. Fineman, Roberta L. Keller Source Type: research

The Need for Echocardiography Alerts for Aortic Stenosis: The Time Has Come
The diagnosis of severe aortic stenosis (SAS) has long been known to be associated with a poor prognosis.1 A recent report by Strange et  al.2 has raised new concerns in patients with even moderate aortic stenosis; this report shows the 5-year all-cause and cardiovascular mortality in patients with moderate aortic stenosis carries twice the mortality risk compared with patients with no aortic stenosis. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 13, 2020 Category: Cardiology Authors: Glenn R. Barnhart, Randolph P. Martin, James D. Thomas, Patrick M. McCarthy Tags: Editorial Comment Source Type: research

Continuing Education and Meeting Calendar
The American Society of Echocardiography is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. ASE recognizes courses as supplements to formal training in an established echocardiographic laboratory. For more information about a course, please call the number listed. To list a course in the Continuing Education and Meeting Calendar, send the date(s), title, location, provider, course director(s), and contact information to ASE, Attn: Education Dept, 2530 Meridian Parkway, Durham, NC 27713; Tel: 919-861-5574 x7161; E-mail: education@asecho.org. (S...
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Source Type: research

Temporal Resolution in the New Decade
I once asked an old friend what his resolution was for the new year. He said “This time it will be different. I'm going to smoke, drink, eat out, and watch more TV.” I stared in disbelief. Noting my reaction, he went on to add, “Since my new year resolutions never work, I decided to try something different. A sort of reverse psychology!” I was visibly relieved that m y friend wasn't headed on a path of self-destruction. However, I realized that embedded in his unique strategy was the phenomenon we are all experience often – managing change is hard. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Authors: Madhav Swaminathan Tags: American Society of Echocardiography News Source Type: research

Table of Contents
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Source Type: research

Editorial Board
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Source Type: research

Guide for Authors
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Source Type: research

Information for Readers
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - January 1, 2020 Category: Cardiology Source Type: research

Echocardiographic Evaluation of Left Ventricular Output in Patients with Heart Failure: A Per-Beat or Per-Minute Approach?
Left ventricular (LV) output is a predictor of adverse outcome in patients with heart failure. It can be evaluated using a per-beat approach, measuring stroke volume index (SVI), or a per-minute approach, calculating cardiac index (CI). However, the prognostic value of these two approaches has never been compared. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 19, 2019 Category: Cardiology Authors: Donato Mele, Gabriele Pestelli, Davide Dal Molin, Filippo Trevisan, Vittorio Smarrazzo, Giovanni Andrea Luisi, Alessandro Fucili, Roberto Ferrari Source Type: research

Postoperative Recovery of Left Ventricular Function following Repair of Large Ventricular Septal Defects in Infants
This study aims to characterize the incidence and rate of recovery of postoperative LV dysfunction following repair of large VSDs and to improve understanding of LV mechanics before and after VSD repair. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 19, 2019 Category: Cardiology Authors: Gregory T. Adamson, Alisa Arunamata, Theresa A. Tacy, Norman H. Silverman, Michael Ma, Shiraz A. Maskatia, Rajesh Punn Source Type: research

Clinical Usefulness of Pressure Recovery Adjustment in Patients with Predominantly Severe Aortic Stenosis: Asian Valve Registry Data
Adjustment for pressure recovery (PR) may reconcile discrepancies in pressure gradients measured by Doppler echocardiography and direct catheterization in patients with mild to moderately severe aortic stenosis (AS). The aim of this study was to evaluate whether PR adjustment is useful in a large cohort of predominantly patients with severe AS. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 19, 2019 Category: Cardiology Authors: Ran Heo, Xin Jin, Jin Kyung Oh, Yong-Jin Kim, Sung-Ji Park, Seung Woo Park, Lieng-Hsi Ling, Shota Fukuda, Yutaka Otsuji, Dae-Won Sohn, Jae-Kwan Song Source Type: research

Meta-Analysis of Optimal Allometric Exponent for Indexing of Echocardiographic Left Ventricular Mass
Measurements of left ventricular mass (LVM) need to account for differences in patients' body size. Although this can be done by dividing LVM by, for example, body surface area, dividing by height raised to a power exponent (b), known as allometric indexing, has been proposed as potentially superior.1-3 Uptake in clinical practice has been slow, however, because a range of different values have been proposed for b.1,4 We wished to combine estimates of b provided in earlier reports. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 19, 2019 Category: Cardiology Authors: Anders Sahl én, See Hooi Ewe, Zee Pin Ding Tags: Brief Research Communication Source Type: research

Systematic Assessment of the Impact of Ultrasound-Enhancing Agents upon Measurements of Cardiac Size and Function by Echocardiography
Echocardiography with an ultrasound-enhancing contrast agent (CON) is a powerful tool for identifying the endocardial border. However, the precise relationship of measurements obtained from CON to the reference values of two-dimensional unenhanced echocardiography (BASL) remains undefined, especially regarding wall thickness. The aim of this study was to systematically determine the differences between unenhanced and enhanced images for a broad range of left ventricular (LV) measurements and to define reference values for the relationship between the two methods. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 18, 2019 Category: Cardiology Authors: Sachiyo Igata, Megan Kraushaar, Monet Strachan, Janet I. Ma, Marin Nishimura, Ajit Raisinghani, Daniel G. Blanchard, Anthony N. DeMaria Source Type: research

System-Wide Echocardiography Accreditation: Physician Perceptions and Concerns
Echocardiography accreditation at outpatient imaging facilities has been reported to improve diagnostic quality, reduce interpretative variability, and increase imaging appropriateness.1-3 Historically, outpatient echocardiography facilities have individually applied for Intersocietal Accreditation Commission (IAC) accreditation. However, some health systems have recently experimented with “system-wide accreditation,” in which all of a hospital's affiliated echocardiography facilities apply for accreditation under the same IAC application and standards. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 18, 2019 Category: Cardiology Authors: Benjamin Pockros, Aniksha Balamurugan, Jacob Radparvar, Jon A. Chilingerian, Mylan Cohen Tags: Letter to the Editor Source Type: research

Focused Cardiac Ultrasound: A Prospective Randomized Study of Simulator-Based Training
In 2014, international evidence-based recommendations defined focused cardiac ultrasound (FoCUS) and its implementation and indications.1 It is recommended and currently used in critical care medicine, anesthesiology, emergency medicine, and internal medicine.2-5 In FoCUS, image acquisition requires the learning of five views1: parasternal short axis (PSA), parasternal long axis (PLA), apical four chambers (AFC), subcostal four chambers (SFC), and inferior vena cava (IVC) view. Comprehension of the anatomy and the probe position compared with the heart is essential. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 18, 2019 Category: Cardiology Authors: Mathilde Chaptal, Ludivine Tendron, Pierre-G éraud Claret, Laurent Muller, Thibaut Markarian, Laurent Mattatia, Claire Roger, Jean Emmanuel de la Coussaye, Thierry Pelaccia, Xavier Bobbia Tags: Letter to the Editor Source Type: research

Clinical Impact of Size, Shape, and Orientation of the Tricuspid Annulus in Tricuspid Regurgitation as Assessed by Three-Dimensional Echocardiography
Tricuspid annuloplasty for tricuspid regurgitation (TR) depends on the measurements of tricuspid annular diameter (TAD) obtained in an apical four-chamber view on two-dimensional (2D) transthoracic echocardiography (TTE). We performed a combined 2D and three-dimensional (3D) echocardiographic study to understand the impact of the size, shape, and orientation of a dilated annulus on the inconsistencies between measured 2D TTE-TAD and the actual annular diameter. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 16, 2019 Category: Cardiology Authors: Hiroto Utsunomiya, Yuji Itabashi, Sayuki Kobayashi, Florian Rader, Robert J. Siegel, Takahiro Shiota Source Type: research

Importance of Abdominal Compression Valsalva Maneuver and Microbubble Grading in Contrast Transthoracic Echocardiography for Detecting Patent Foramen Ovale
Although transthoracic echocardiography (TTE) may be useful for patent foramen ovale (PFO) screening, the optimal methodologies remain unclear. The aims of this study were to evaluate the efficacy of the abdominal compression Valsalva maneuver and identify the optimal cutoff value of microbubbles in contrast TTE for detecting PFO, compared with transesophageal echocardiography and catheterization as the reference. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 16, 2019 Category: Cardiology Authors: Yoichi Takaya, Nobuhisa Watanabe, Madoka Ikeda, Teiji Akagi, Rie Nakayama, Koji Nakagawa, Norihisa Toh, Hiroshi Ito Source Type: research

Parameters of Right Ventricular Function Reveal Ventricular-Vascular Mismatch as Determined by Right Ventricular Stroke Work versus Pulmonary Vascular Resistance in Children with Pulmonary Hypertension
Right ventricular (RV) failure, a determinant of outcomes in pulmonary hypertension (PH), occurs when the right ventricle cannot compensate for increased afterload. The authors showed that RV stroke work (RVSW) can be estimated in children with PH as the product of stroke volume and RV pressure and is related to adverse outcomes. The aim of this study was to test the hypothesis that ventricular-vascular (VV) mismatch (high afterload and low RVSW) is associated with echocardiographic measures of RV performance and adverse outcomes. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 10, 2019 Category: Cardiology Authors: Michael V. Di Maria, Kristen R. Campbell, Dale A. Burkett, Adel K. Younoszai, Bruce F. Landeck, Luc Mertens, D. Dunbar Ivy, Kendall S. Hunter, Mark K. Friedberg Source Type: research

The Association between Left Ventricular Diastolic Dysfunction and Myocardial Scar and Their Collective Impact on All-Cause Mortality
Left ventricular diastolic dysfunction (DD) and myocardial scar are important contributors to cardiovascular morbidity and mortality. The aim of this study was to test the hypothesis that myocardial scar is a substrate of DD and that collectively they contribute to increased risk for all-cause mortality. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 10, 2019 Category: Cardiology Authors: Lin Wang, Harsimar Singh, Rajasekhar R. Mulyala, Jonathan Weber, Eddy Barasch, J. Jane Cao Source Type: research

Blood Stasis Imaging Predicts Cerebral Microembolism during Acute Myocardial Infarction
Cardioembolic stroke is a major source of mortality and disability worldwide. The authors hypothesized that quantitative characterization of intracardiac blood stasis may be useful to determine cardioembolic risk in order to personalize anticoagulation therapy. The aim of this study was to assess the relationship between image-based metrics of blood stasis in the left ventricle and brain microembolism, a surrogate marker of cardiac embolism, in a controlled animal experimental model of acute myocardial infarction (AMI). (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 5, 2019 Category: Cardiology Authors: Antonia Delgado-Montero, Pablo Martinez-Legazpi, M. Mar Desco, Daniel Rodr íguez-Pérez, Fernando Díaz-Otero, Lorenzo Rossini, Candelas Pérez del Villar, Elena Rodríguez-González, Christian Chazo, Yolanda Benito, Oscar Flores, José Carlos Antoranz, Source Type: research

Therapeutic Ultrasound Improves Myocardial Blood Flow and Reduces Infarct Size in a Canine Model of Coronary Microthromboembolism
Therapeutic ultrasound (TUS) has been used to lyse infarct-related coronary artery thrombus. There has been no study examining the effect of TUS specifically on myocardial microthromboemboli seen in acute myocardial infarction and acute coronary syndromes. The aim of this study was to test the hypothesis that TUS improves myocardial blood flow (MBF) and reduces infarct size (IS) in this situation by dissolving myocardial microthrombi. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 4, 2019 Category: Cardiology Authors: Mrinal Yadava, D. Elizabeth Le, Igor V. Dykan, Marjorie R. Grafe, Matthew Nugent, Azzdine Y. Ammi, David Giraud, Yan Zhao, Jessica Minnier, Sanjiv Kaul Source Type: research

The Impact of Distinct Exercise Training Modalities on Echocardiographic Measurements in Patients with Heart Failure with Reduced Ejection Fraction
Exercise training is an important component of multidisciplinary heart failure management. However, the effects of aerobic training (AT) versus resistance training (RT) on cardiac function in patients with heart failure with reduced ejection fraction are not well defined. The aim of this study was to evaluate the impact of these exercise modalities on echocardiographic parameters. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 4, 2019 Category: Cardiology Authors: Nick S.R. Lan, Kaitlyn Lam, Louise H. Naylor, Daniel J. Green, Novia S. Minaee, Peter Dias, Andrew J. Maiorana Source Type: research

Cardiac Remodeling in Middle-Aged Endurance Athletes and Recreationally Active Individuals: Challenges in Defining the “Athlete's Heart”
Chronic endurance exercise is known to elicit cardiac morphologic and functional adaptations collectively known as the “athlete's heart.”1 Yet the extent to which exercise burden and other phenotypic factors dictate the extent of cardiac remodeling remains understudied. While there are significant data in younger, elite athletes, reference values for cardiac morphology in long-standing, middle-aged endurance ath letes (EAs) performing high-volume exercise, particularly when compared with recreationally active adults (RECs) who perform recommended levels of physical activity, remain limited. (Source: Journal of ...
Source: Journal of the American Society of Echocardiography - December 4, 2019 Category: Cardiology Authors: Laura Banks, Robert F. Bentley, Katharine D. Currie, Emily Vecchiarelli, Arfa Aslam, Kim A. Connelly, Andrew T. Yan, Kaja M. Konieczny, Paul Dorian, Susanna Mak, Zion Sasson, Jack M. Goodman Tags: Brief Research Communication Source Type: research

Longitudinal Study by Two-Dimensional Speckle-Tracking Echocardiography of the Left Ventricle Rotational Mechanics during Postnatal Adaptation in Healthy Newborns
Improvements in the assessment of cardiac function have led to a better understanding of the different mechanisms involved in normal left ventricular (LV) function.1 Two-dimensional speckle-tracking echocardiography is a well-validated method to assess the rotational mechanics of the heart. Among them, the LV twist mechanism is defined by the net apex-to-base rotation difference and refers to the LV wringing motion during systole.2 Based on recent works focused on the analysis of the orientation of myocardial fibers in fetal and neonatal hearts using polarized imaging, we hypothesized that the onset of the LV twist occurre...
Source: Journal of the American Society of Echocardiography - December 4, 2019 Category: Cardiology Authors: Johanne Auriau, Ba Luu Truong, St éphanie Douchin, Hélène Bouvaist, Gabrielle Michalowicz, Yves Usson, Pierre-Simon Jouk Tags: Brief Research Communication Source Type: research

Avoiding Mistakes of the Past with Tricuspid Regurgitation
In 1967, Nina Braunwald and colleagues1 reported that mitral valve replacement would uniformly result in spontaneous resolution of tricuspid regurgitation (TR) obviating the need for intervention. We now know that this conservative approach has contributed to the severe undertreatment of the disease2,3 and resulted in a population of patients who have incurred excessive risk during repeat surgery.4,5 Secondary TR is associated with poor outcomes in a number of disease states.6-9 Whether TR is a marker of these comorbidities or an independent predictor of outcomes has been debated in the setting of the complex anatomic and ...
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Authors: Rebecca T. Hahn Tags: Editorial Comment Source Type: research

Continuing Education and Meeting Calendar
The American Society of Echocardiography is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. ASE recognizes courses as supplements to formal training in an established echocardiographic laboratory. For more information about a course, please call the number listed. To list a course in the Continuing Education and Meeting Calendar, send the date(s), title, location, provider, course director(s), and contact information to ASE, Attn: Education Dept, 2530 Meridian Parkway, Durham, NC 27713; Tel: 919-861-5574 x7161; E-mail: education@asecho.org. (S...
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Tags: American Society of Echocardiography News Source Type: research

The Role of the Cardiac Sonographer in Structural Heart Disease Procedures
If you have the opportunity to attend a national cardiology conference, you will find educational content surrounding structural heart disease (SHD) is arguably one of the hottest topics. This was the case at the 30th Annual ASE Scientific Sessions held in Portland, Oregon this past June. The Imaging Essentials track on Saturday was dedicated to SHD topics, including fundamentals of hemodynamics, guideline-based valvular disease assessment, 3-dimensional (3D) technology-guided therapy, and the sonographer's role in interventional SHD procedures. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Authors: Amy Dillenbeck Tags: American Society of Echocardiography News Source Type: research

Lifelong Learning in the Era of Digital Ubiquity: From Empty Classrooms to Full Experiences
I recently saw a post on social media in which a biochemistry professor described giving a lecture in an empty classroom.1 It wasn't to an empty classroom though. There's a subtle difference in wording, but a significant distinction between the two. The lecture was recorded and he provided several possible explanations for the physical absence of learners, including the time of the day, post-test exhaustion, and his teaching style. However, it was obvious that there were a couple of lessons embedded in his experience. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Authors: Madhav Swaminathan Tags: American Society of Echocardiography News Source Type: research

Table of Contents
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Source Type: research

Editorial Board
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Source Type: research

Information for Readers
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - December 1, 2019 Category: Cardiology Source Type: research

Variability in Echocardiographic Ascending Aortic Diameters due to Image Acquisition by Different Sonographers
Aortic dilatation carries an increased risk of aortic dissection, with high mortality and morbidity rates.1 To diagnose aortic dilatation and determine the need for preventive intervention, reliable measurement of the aortic diameter is crucial.2,3 The ascending aortic (AA) diameter can be assessed with different imaging modalities: computed tomography (CT), cardiovascular magnetic resonance imaging (CMR), and echocardiography. Because echocardiographic images are handmade by the sonographer, echocardiography is more operator dependent than CT and CMR, which induces additional variability in aortic measurements. (Source: J...
Source: Journal of the American Society of Echocardiography - November 27, 2019 Category: Cardiology Authors: Lidia R. Bons, Allard T. van den Hoven, Jackie S. McGhie, An M. van Berendoncks, Ellen J.A. Wiegers-Groeneweg, Lourus W. van Haveren, Dan J. Bowen, Annemien E. van den Bosch, Judith A.A. E. Cuypers, Robert M. Kauling, Ricardo P.J. Budde, Jolien W. Roos-He Tags: Brief Research Communication Source Type: research

Guidelines for Performance, Interpretation, and Application of Stress Echocardiography in Ischemic Heart Disease: From the American Society of Echocardiography
Since the 2007 publication of the American Society of Echocardiography (ASE) guidelines for stress echocardiography,1 new information has become available about the methodology of stress echocardiography, including test protocols, standards for interpretation (including quantitative methods of assessment and application of strain rate imaging), appropriateness of testing, comparison with other modalities for assessing ischemic heart disease (IHD), safety of stress echocardiography, application of the technique in children and special populations, prognostic value, and role of ultrasound enhancing agents (UEA) and perfusion...
Source: Journal of the American Society of Echocardiography - November 15, 2019 Category: Cardiology Authors: Patricia A. Pellikka, Adelaide Arruda-Olson, Farooq A. Chaudhry, Ming Hui Chen, Jane E. Marshall, Thomas R. Porter, Stephen G. Sawada Tags: Guidelines and Standards Source Type: research

Intraoperative Provocative Testing in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy
Resolution of left ventricular outflow tract (LVOT) obstruction predicts symptom relief postmyectomy. Intraoperative measurement of LVOT gradients thus is essential for surgical guidance. We hypothesized that (1) hypertrophic cardiomyopathy patients have lower LVOT gradients when measured intraoperatively with transesophageal echocardiography (TEE) compared with preoperative measurements with transthoracic echocardiography (TTE) and that (2) intraoperative provocative testing can help evaluate the adequacy of surgical resection. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - November 15, 2019 Category: Cardiology Authors: Ali Bedair Elsayes, Alaa Basura, Farhad Zahedi, Ingrid Moreno-Duarte, Ethan J. Rowin, Martin Maron, Hassan Rastegar, Frederick C. Cobey Source Type: research

Left Ventricular Longitudinal Strain as a Marker for Point of No Return in Hypertensive Heart Failure Treatment
There are currently no therapies that can improve prognosis in cases of heart failure (HF) with preserved ejection fraction (EF). We hypothesized that there is a point of no return after which no response to treatment is noted and that for the prevention of hypertensive HF this point may be determined by left ventricle (LV) strain, in the prevention of hypertensive HF. Here an angiotensin-converting enzyme inhibitor (ACE-I) was initiated based on myocardial strain imaging and its effects were determined in an animal model. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - November 15, 2019 Category: Cardiology Authors: Tomoko Ishizu, Yoshihiro Seo, Mikiko Namekawa, Nobuyuki Murakoshi, Masaki Ieda, Yasushi Kawakami Source Type: research

Effect of Pressure Recovery on Pressure Gradients in Congenital Stenotic Outflow Lesions in Pediatric Patients —Clinical Implications of Lesion Severity and Geometry: A Simultaneous Doppler Echocardiography and Cardiac Catheter Correlative Study
Doppler pressure gradients (PGs) are routinely used as a surrogate for catheter peak-to-peak gradient (PPG) for referring pediatric patients with aortic stenosis (AS), pulmonary stenosis (PS), and coarctation of the aorta (CoA) for intervention but do not always predict the catheter PPG accurately, which results in misclassification of lesion severity. We hypothesized that recovered pressure (RP) accounts for the discrepancy between Doppler PG and catheter PPG. We aimed to study the occurrence of clinically significant RP in AS, PS, and CoA. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - November 5, 2019 Category: Cardiology Authors: Gautam K. Singh, Katie L. Mowers, Cynthia Marino, David Balzer, P. Syamasundar Rao Source Type: research

Functional Regurgitation of Atrioventricular Valves and Atrial Fibrillation: An Elusive Pathophysiological Link Deserving Further Attention
In patients with structurally normal atrioventricular valvular apparatus, functional regurgitation of the mitral or tricuspid valves has been attributed mainly to ventricular dilation and/or dysfunction, through a combination of annulus dilation and tethering of the valve leaflets. The occurrence of functional regurgitation of atrioventricular valves in patients with long-standing persistent atrial fibrillation and atrial dilation but normal ventricular size and function has received much less attention, and its peculiar mechanisms still remain to be understood. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - November 1, 2019 Category: Cardiology Authors: Denisa Muraru, Andrada-Camelia Guta, Roberto Carlos Ochoa-Jimenez, Daniela Bartos, Patrizia Aruta, Sorina Mihaila, Bogdan A. Popescu, Sabino Iliceto, Cristina Basso, Luigi Paolo Badano Source Type: research

20th Annual Feigenbaum Lecture: Echocardiography for Precision Medicine —Digital Biopsy to Deconstruct Biology
This article (based on the 20th annual Feigenbaum Lecture, presented at the 2019 American Society of Echocardiography Scientific Sessions) describes the utility of echocardiography as a “digital biopsy” and how deep quantitative echocardiographic phenotyping, coupled with machine learning, can be used to identify novel HFpEF phenotypes. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Sanjiv J. Shah Tags: 20th Annual Feigenbaum Lecture Source Type: research

Similarities and Differences in Left Ventricular Size and Function among Races and Nationalities: Results of the World Alliance Societies of Echocardiography Normal Values Study
The World Alliance Societies of Echocardiography (WASE) Normal Values Study evaluates individuals from multiple countries and races with the aim of describing normative values that could be applied to the global community worldwide and to determine differences and similarities among people from different countries and races. The present report focuses specifically on two-dimensional (2D) left ventricular (LV) dimensions, volumes, and systolic function. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Federico M. Asch, Tatsuya Miyoshi, Karima Addetia, Rodolfo Citro, Masao Daimon, Sameer Desale, Pedro Gutierrez Fajardo, Ravi R. Kasliwal, James N. Kirkpatrick, Mark J. Monaghan, Denisa Muraru, Kofo O. Ogunyankin, Seung Woo Park, Ricardo E. Ronderos, Anita Tags: Clinical Investigation Source Type: research

Continuing Education and Meeting Calendar
The American Society of Echocardiography is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. ASE recognizes courses as supplements to formal training in an established echocardiographic laboratory. For more information about a course, please call the number listed. To list a course in the Continuing Education and Meeting Calendar, send the date(s), title, location, provider, course director(s), and contact information to ASE, Attn: Education Dept, 2530 Meridian Parkway, Durham, NC 27713; Tel: 919-861-5574 x7161; E-mail: education@asecho.org. (S...
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Tags: American Society of Echocardiography News Source Type: research

Ischemic Memory Imaging: The Quest for the Holy Grail Continues
For patients presenting with acute chest pain, current clinical evaluation rests upon history, physical examination, surface electrocardiography, and serum cardiac biomarkers. The evolution of the latter, particularly toward high-sensitivity troponin assays, has dramatically increased the detection of smaller infarcts, allowed much earlier diagnoses, and improved risk stratification.1,2 Despite this widespread adoption, the clinical entity of “unstable angina” (UA), whereby supply-demand mismatch occurs but ischemic time is not sufficient to cause myocyte necrosis and biomarker release, remains a real and chall...
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Yin Ge, Howard Leong-Poi Tags: Editorial Comment Source Type: research

Barriers to Sonographer Education
Conferences are the perceived pinnacle of an educational experience. The event can plant the seeds of curiosity and allow a sonographer to gather meaningful information to bring back to their lab. Every year, as major societies host scientific sessions, sonographers yearn to earn their “golden ticket.” Decisions are made whether sonographers will be able to attend educational events based on available funds in the department. In response to the shortage of funding, sonographers search out additional pathways of support. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Neha Soni-Patel Tags: American Society of Echocardiography News Source Type: research

The ASE Leadership Academy: “Reap What You Sow” and Other Gardening Metaphors
“You reap what you sow.” Modified from an original Biblical reference, this quote applies to so many settings, and a professional society like ASE is hardly exempt. Continuing the gardening metaphor, investing in leadership is like tending to a garden with horticultural diversity. Different plan ts have distinct needs. From sunshine, to water, to nourishment, to temperature, they all thrive under a variety of settings but more importantly, perish without them. A monocultural approach is often fatal to the growth of a multicultural organization. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Madhav Swaminathan Tags: American Society of Echocardiography News Source Type: research

Table of Contents
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Source Type: research

Editorial Board
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Source Type: research

Information for Readers
(Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Source Type: research

Use of the Valve Visualization on Echocardiography Grade Tool Improves Sensitivity and Negative Predictive Value of Transthoracic Echocardiogram for Exclusion of Native Valvular Vegetation
Transesophageal echocardiography (TEE) remains the preferred test to rule out infective endocarditis (IE) but is resource intensive and carries risk. Multiple studies report low sensitivity of transthoracic echocardiography (TTE) for detection of IE; however, these studies did not account for TTE quality. We test the validity of a simple valve visualization grading tool to stratify TTEs by quality and determine whether a high-quality TTE may be used to exclude valvular vegetation and forgo the need for TEE. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 31, 2019 Category: Cardiology Authors: Katherine Connolly, Geraldine Ong, Michael Kuhlmann, Edwin Ho, Kevin Levitt, Husam Abdel-Qadir, Jeremy Edwards, Chi-Ming Chow, Mohammed-Salah Annabi, Ezequiel Guzzetti, Erwan Salaun, Philippe Pibarot, Idan Roifman, Howard Leong-Poi, Kim A. Connelly Source Type: research

Adherence to the American Society of Echocardiography and European Association of Cardiovascular Imaging Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: A Quality Improvement Project
Echocardiographic assessment of diastolic dysfunction is challenging due to complex underlying physiology, the number of diastolic parameters that can be obtained by echocardiography, and the need for integration of the results of multiple indices to reach an appropriate classification.1 In 2016, a joint task force of the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI) published an update recommendation for evaluation of left ventricular (LV) diastolic function by echocardiography. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - October 24, 2019 Category: Cardiology Authors: Fahmi Othman, Galal Abushahba, Alessandro Salustri Tags: Letter to the Editor Source Type: research