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Condition: Cirrhosis

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Total 302 results found since Jan 2013.

Liver Cirrhosis Tied to Increased Stroke Risk Liver Cirrhosis Tied to Increased Stroke Risk
A study challenges the notion that ischemic stroke does not occur in patients with liver cirrhosis and calls for heightened awareness of the risk for hemorrhagic stroke in these patients, researchers say.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - March 7, 2017 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Forced Vital Capacity Predicts Morbidity and Mortality in Adult Patients with Fontan Circulation
Due to advances in cardiology and cardiac surgery, the 15-year survival after the Fontan operation for palliation of single-ventricle congenital heart disease (CHD) is now over 90% [1,2]. However, survivors with Fontan circulation are at risk for developing long-term complications that include exercise intolerance, congestive heart failure, protein losing enteropathy, plastic bronchitis, arrhythmias, stroke, and cirrhosis, all of which contribute to the risk for hospitalization and death in long-term follow-up [2 –6].
Source: Progress in Pediatric Cardiology - January 27, 2017 Category: Cardiology Authors: Katie E. Cohen, Matthew Buelow, Jennifer Dixon, Ruta Brazauskas, Scott Cohen, Michael G. Earing, Salil Ginde Source Type: research

Apelin/APJ system: A novel promising therapy target for pathological angiogenesis
In conclusion, the Apelin/APJ system would be a promising therapeutic target for angiogenesis-related diseases.
Source: Clinica Chimica Acta - January 17, 2017 Category: Laboratory Medicine Source Type: research

The efficacy and safety of direct oral anticoagulants vs traditional anticoagulants in cirrhosis
ConclusionsDirect oral anticoagulant use in patients with cirrhosis may be as safe as traditional anticoagulants. Patients with cirrhosis at our center prescribed DOACs had less major bleeding events, while maintaining efficacy at preventing stroke or thrombosis.
Source: European Journal of Haematology - January 14, 2017 Category: Hematology Authors: Justine Hum, Joseph J. Shatzel, Janice H. Jou, Thomas G. Deloughery Tags: ORIGINAL ARTICLE Source Type: research

Is cirrhosis associated with lower odds of ischemic stroke: A nationwide analysis?
CONCLUSION: Our study suggests that in a large, nationally representative sample of the United States population, cirrhosis is associated with a lower likelihood of stroke. PMID: 28050237 [PubMed]
Source: World Journal of Hepatology - January 6, 2017 Category: Gastroenterology Tags: World J Hepatol Source Type: research

Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition
ConclusionConcomitant narcotic use and diabetes have a compounding effect on the quality of bowel preparation prior to colonoscopy.
Source: Digestive Diseases and Sciences - December 28, 2016 Category: Gastroenterology Source Type: research

The efficacy and safety of direct oral anticoagulants vs. traditional anticoagulants in cirrhosis
ConclusionsDOAC use in cirrhotics may be as safe as traditional anticoagulants. Patients with cirrhosis at our center prescribed DOACs had less major bleeding events, while maintaining efficacy at preventing stroke or thrombosis.This article is protected by copyright. All rights reserved.
Source: European Journal of Haematology - December 22, 2016 Category: Hematology Authors: Justine Hum, Joseph J. Shatzel, Janice H. Jou, Thomas G. Deloughery Tags: Original Article Source Type: research

Apelin/APJ system: A novel promising therapy target for pathological angiogenesis.
In conclusion, the Apelin/APJ system would be a promising therapeutic target for angiogenesis-related diseases. PMID: 28025030 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - December 22, 2016 Category: Chemistry Authors: Wu L, Chen L, Li L Tags: Clin Chim Acta Source Type: research

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research

Alcoholic cardiomyopathy : The result of dosage and individual predisposition.
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Historical exa...
Source: Herz - September 3, 2016 Category: Cardiology Tags: Herz Source Type: research

Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables: A prospective study of diagnostic accuracy
The objective was to evaluate SV and arterial pressure fluid responsiveness in liver cirrhosis patients by using dynamic preload and vascular tone variables. DESIGN: A prospective study of diagnostic accuracy. SETTINGS: A single-centre trial conducted from November 2013 to April 2015. PATIENTS: Thirty-one adult patients, recipients of a living donor liver transplantat. INTERVENTION: An intraoperative fluid challenge with 10 ml kg−1 of 0.9% normal saline. MAIN OUTCOME MEASURES: PPV, SVV, cardiac index and systemic vascular resistance index were measured using the Pulse index Continuous cardiac system. The PVI and...
Source: European Journal of Anaesthesiology - August 3, 2016 Category: Anesthesiology Tags: Cardiovascular physiology Source Type: research

Cardiac Remodeling in Patients With Primary and Secondary Aldosteronism: A Tissue Doppler Study Ventricular Structure and Function
Conclusions— Primary and secondary hyperaldosteronism correlate with LV enlargement and high prevalence of LV hypertrophy and diastolic dysfunction; a subclinical systolic dysfunction is evident only in PA. In SA, the high rate of LV hypertrophy, in spite of low peripheral resistances and low-to-normal blood pressure, could be accounted for the high renin and aldosterone values, and the work overload associated with a hyperdynamic circulatory state.
Source: Circulation: Cardiovascular Imaging - June 14, 2016 Category: Radiology Authors: Cesari, M., Letizia, C., Angeli, P., Sciomer, S., Rosi, S., Rossi, G. P. Tags: ACE/Angiotensin Receptors/Renin Angiotensin System, Clinical Studies, Hypertrophy, Hypertension, Echocardiography Ventricular Structure and Function Source Type: research

Point-of-Care Echocardiography Improves Assessment of Volume Status in Cirrhosis and Hepatorenal Syndrome.
Abstract The management of patients with cirrhosis along with acute kidney injury is complex and depends in large part on accurate assessment of intravascular volume status. Assessment of intravascular volume status by point-of-care echocardiography often relies solely on inferior vena cava size and variability evaluation; however, this parameter should be interpretated with an understanding of right ventricular function integrated with stroke volume and flow. Attempts to optimize intra-abdominal hemodynamics favorably are clearly problematic when physical examination findings or rudimentary assessments of central...
Source: The American Journal of the Medical Sciences - April 30, 2016 Category: Journals (General) Authors: Huggins JT, Doelken P, Walters C, Rockey DC Tags: Am J Med Sci Source Type: research

Imaging of a Fatal Air Embolism from ERCP (P4.363)
CONCLUSIONS: Though most of the occurrences in relation to ERCP are portal venous air embolisms, which are absorbed spontaneously, serious and sometimes fatal complications have occurred including arterial air embolisms causing multiorgan damage including cerebral infarcts. Case history, pertinent imaging and pathological findings are discussed to bring awareness of this rare complication of ERCP and emphasize its early recognition. Disclosure: Dr. Jens has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ibrahimi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Jens, W., Lee, A., Ibrahimi, M. Tags: Cerebrovascular Case Reports Source Type: research

Burden and Outcomes of Acute Ischemic Stroke in Patients with Cirrhosis (P5.218)
Conclusions: Our study displayed an increasing proportion of cirrhotic patients admitted due to AIS in the last decade. This burden is associated with worse outcomes and warrants further investigation.Disclosure: Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Onteddu has nothing to disclose. Dr. Mehta has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Lunagariya, A., Patel, A., Shah, H., Onteddu, S., Mehta, S. Tags: Cerebrovascular Disease: Genetics and Risk Factor Variation Source Type: research