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Condition: Cirrhosis

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Total 302 results found since Jan 2013.

Letter to the Editor: An isolated insular stroke mimics a bout of overt hepatic encephalopathy in a patient with cirrhosis
The manifestations of hepatic encephalopathy (HE) vary from mild neuropsychiatric abnormalities to coma 1,2. Diagnosis and differential diagnosis can be challenging, especially in the hospital setting, where patients may suffer from other metabolic encephalopathies or neurological/psychiatric disorders 1,2,3. Moreover, HE might also occur on top of pre-existing disease, such as dementia 1. Any potential HE precipitating factor should be identified and treated promptly 1. In patients with delirium and cirrhosis, even those with a working diagnosis of HE, a set of laboratory tests including a full blood count, glucose, elect...
Source: Journal of Hepatology - March 19, 2023 Category: Gastroenterology Authors: Chiara Mangini, Roberta Gagliardi, Francesco Causin, Paolo Angeli, Sara Montagnese Tags: Letter to the Editor Source Type: research

An isolated insular stroke mimics a bout of overt hepatic encephalopathy in a patient with cirrhosis
The manifestations of hepatic encephalopathy (HE) vary from mild neuropsychiatric abnormalities to coma.1,2 Diagnosis and differential diagnosis can be challenging, especially in the hospital setting, where patients may suffer from other metabolic encephalopathies or neurological/psychiatric disorders.1 –3 Moreover, HE might also occur on top of pre-existing disease, such as dementia.1 Any potential HE precipitating factor should be identified and treated promptly.1 In patients with delirium and cirrhosis, even those with a working diagnosis of HE, a set of laboratory tests including a full blood count, glucose, electrol...
Source: Journal of Hepatology - March 19, 2023 Category: Gastroenterology Authors: Chiara Mangini, Roberta Gagliardi, Francesco Causin, Paolo Angeli, Sara Montagnese Tags: Letter to the Editor Source Type: research

Hepatitis C Infection as a Risk Factor for Hypertension and Cardiovascular Diseases: An EpiTer Multicenter Study
J Clin Med. 2022 Sep 1;11(17):5193. doi: 10.3390/jcm11175193.ABSTRACTHepatitis C infection is one of the main reasons for liver cirrhosis and hepatocellular carcinoma. In recent years, more and more is being heard about extrahepatic manifestations of the hepatitis C infection including its possible influence on the development of hypertension and cardiovascular diseases. In the given work, the frequency analysis of the incidence of hypertension and cardiovascular diseases among 2898 HCV-infected patients treated in Poland and the assessment of their relevance to the HCV genotype and the progression of liver fibrosis can be...
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Pawe ł Rajewski Dorota Zar ębska-Michaluk Ewa Janczewska Andrzej Gietka W łodzimierz Mazur Magdalena Tudrujek-Zdunek Krzysztof Tomasiewicz Teresa Belica-Wdowik Barbara Baka- Ćwierz Dorota Dybowska Waldemar Halota Beata Lorenc Marek Sitko Aleksander Ga Source Type: research

Reduction in the risk of major adverse cardiovascular events with the BET protein inhibitor apabetalone in patients with recent acute coronary syndrome, type 2 diabetes, and moderate to high likelihood of non-alcoholic fatty liver disease
CONCLUSIONS: Amongst patients with T2DM, recent ACS, and a moderate-to-high likelihood of advanced liver fibrosis, apabetalone was associated with a significantly lower rate of ischemic MACE and HHF and attenuated the increase in hepatic FS over time.PMID:36039183 | PMC:PMC9419281 | DOI:10.1016/j.ajpc.2022.100372
Source: Atherosclerosis - August 30, 2022 Category: Cardiology Authors: Peter P Toth Gregory G Schwartz Stephen J Nicholls Aziz Khan Michael Szarek Henry N Ginsberg Jan O Johansson Kamyar Kalantar-Zadeh Ewelina Kulikowski Ken Lebioda Norman C W Wong Michael Sweeney Kausik K Ray BETonMACE Investigators Source Type: research

Non-alcoholic fatty liver disease and incident major adverse cardiovascular events: results from a nationwide histology cohort
Conclusion Compared with matched population controls, patients with biopsy-proven NAFLD had significantly higher incidence of MACE, including IHD, stroke, CHF and CV mortality. Excess risk was evident across all stages of NAFLD and increased with worsening disease severity.
Source: Gut - August 11, 2022 Category: Gastroenterology Authors: Simon, T. G., Roelstraete, B., Hagström, H., Sundström, J., Ludvigsson, J. F. Tags: Gut Hepatology Source Type: research

Complete alcohol abstinence increases the risk of NAFLD but not severity. A population analysis with transient elastography
CONCLUSION: Interestingly, modest alcohol consumption is associated with decreased odds of NAFLD. Further investigations are required to examine the relationship between alcohol consumption and NAFLD and subsequently the potential impact on NAFLD management.PMID:35944527 | DOI:10.1080/00365521.2022.2105168
Source: Scandinavian Journal of Gastroenterology - August 9, 2022 Category: Gastroenterology Authors: Jieling Xiao Cheng Han Ng Kai En Chan Ansel Shao Pin Tang Readon Teh Abel Ho Zhi Ling Jie Ning Yong Wen Hui Lim Darren Jun Hao Tan Caitlyn Tan Khin Maung Win Aung Hlaing Bwa Nicholas W S Chew Daniel Huang Yock Young Dan Mazen Noureddin Mohammad Shadab Sid Source Type: research

Effect of norepinephrine on blood volume, cardiac output, and systemic filling pressure in patients undergoing liver transplantation
CONCLUSIONS: The norepinephrine infusion at 0.1 μg-1 kg-1 min-1 is associated with an increase in CO in patients with liver cirrhosis undergoing liver transplantation. Norepinephrine's effect on CO was primarily attributable to an increase in venous return due to an increase in mean systemic filling pressure.PMID:35833856 | DOI:10.23736/S0375-9393.22.16526-0
Source: Minerva Anestesiologica - July 14, 2022 Category: Anesthesiology Authors: Ahmed M Mukhtar Ehab T Fahmy Akram A Eladawy Mohamed Ali Mohamed Elayashy Fuat Saner Amr Abdelaal Mostafa Abdo Amr S Hussein Source Type: research