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Condition: Cirrhosis
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Total 302 results found since Jan 2013.
Effect of norepinephrine on blood volume, cardiac output, and systemic filling pressure in patients undergoing liver transplantation
CONCLUSIONS: The norepinephrine infusion at 0.1 μg-1 kg-1 min-1 is associated with an increase in CO in patients with liver cirrhosis undergoing liver transplantation. Norepinephrine's effect on CO was primarily attributable to an increase in venous return due to an increase in mean systemic filling pressure.PMID:35833856 | DOI:10.23736/S0375-9393.22.16526-0
Source: Minerva Anestesiologica - July 14, 2022 Category: Anesthesiology Authors: Ahmed M Mukhtar Ehab T Fahmy Akram A Eladawy Mohamed Ali Mohamed Elayashy Fuat Saner Amr Abdelaal Mostafa Abdo Amr S Hussein Source Type: research
The Footprint of Kynurenine Pathway in Cardiovascular Diseases
Int J Tryptophan Res. 2022 Jun 28;15:11786469221096643. doi: 10.1177/11786469221096643. eCollection 2022.ABSTRACTKynurenine pathway is the main route of tryptophan metabolism and produces several metabolites with various biologic properties. It has been uncovered that several cardiovascular diseases are associated with the overactivation of kynurenine pathway and kynurenine and its metabolites have diagnostic and prognostic value in cardiovascular diseases. Furthermore, it was found that several kynurenine metabolites can differently affect cardiovascular health. For instance, preclinical studies have shown that kynurenine...
Source: Atherosclerosis - July 5, 2022 Category: Cardiology Authors: Moein Ala Seyed Parsa Eftekhar Source Type: research
Blunted cardiovascular effects of beta-blockers in patients with cirrhosis: Relation to severity?
ConclusionWe found the effect of beta-blockade on cardiac index in patients with advanced cirrhosis to be less potent than in patients with early cirrhosis, indicating that underlying cirrhotic cardiomyopathy increases, and the cardiac compensatory reserve becomes more compromised, with disease progression. The differential effects of beta-blockade in the left atrium may be used to predict the effect of beta-blockers on portal pressure, but further studies are needed to investigate this possibility.
Source: PLoS One - June 28, 2022 Category: Biomedical Science Authors: Puria Nabilou Source Type: research
Liver Cirrhosis Tied to Elevated Risk for Stroke
(MedPage Today) -- Liver cirrhosis was linked to a greater risk for stroke in a large retrospective study, and the association was independent of established cardiovascular risk factors, a research reported.
In the study of nearly 1.3 million...
Source: MedPage Today Cardiovascular - June 26, 2022 Category: Cardiology Source Type: news
Cancers, Vol. 14, Pages 2977: Association between Breast Cancer and Second Primary Lung Cancer among the Female Population in Taiwan: A Nationwide Population-Based Cohort Study
Conclusion: Patients with breast cancer had a significantly higher risk of developing second primary lung cancer compared with patients without breast cancer, particularly in younger groups and in those without any comorbidities. The special association may be attributed to some potential risk factors such as genetic susceptibility and long-term exposure to PM2.5, and is supposed to increase public awareness. Further studies are necessary given the fact that inherited genotypes, different subtypes of breast cancer and lung cancer, and other unrecognized etiologies may play vital roles in both cancers’ development.
Source: Cancers - June 16, 2022 Category: Cancer & Oncology Authors: Fan-Wen Lin Ming-Hsin Yeh Cheng-Li Lin James Cheng-Chung Wei Tags: Article Source Type: research
Po-685-06 liver cirrhosis is associated with an increase in bleeding and mortality in patients undergoing left atrial appendage occlusion: insights from a nationwide cohort analysis
Patients with liver cirrhosis are at an increased risk of bleeding secondary to diminished clotting factor synthesis. In patients with both atrial fibrillation (AF) and cirrhosis, there is an additional risk of cardioembolic stroke. Thus, left atrial appendage occlusion (LAAO) is an attractive therapeutic option. There is limited data available that examine the safety and outcomes of LAAO in patients with cirrhosis.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Sahith Reddy Thotamgari, Aakash Sheth, Samarthkumar Thakkar, Harsh P. Patel, Abhishek J. Deshmukh, Christopher V. DeSimone Source Type: research
Liver cirrhosis is independently associated with increased in-hospital mortality in patients undergoing left atrial appendage occlusion device implantation
This study aimed to assess procedural outcomes in patients with cirrhosis who underwent LAAO with a Watchman device by using a contemporary administrative claims database.
Source: Heart Rhythm - April 28, 2022 Category: Cardiology Authors: Sahith Reddy Thotamgari, Aakash R. Sheth, Harsh P. Patel, John Bretzman, Robert C. Ward, Samarthkumar Thakkar, Jaimin T. Patel, Samuel J. Asirvatham, David R. Holmes, Alexander Egbe, Abhishek Deshmukh, Christopher V. DeSimone Tags: Research Letter Source Type: research
Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
CONCLUSIONS: 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.PMID:35396285 | DOI:10.1136/bmjopen-2021-054111
Source: Cancer Control - April 9, 2022 Category: Cancer & Oncology Authors: Peng Yeong Woon Jia-Ying Chien Jen-Hung Wang Yu-Yau Chou Mei-Chen Lin Shun-Ping Huang Source Type: research
Amoxicillin/clavulanic acid-associated severe neutropenia
A 72-year-old man presented with an abnormal blood count and was admitted. His history included hypertension and hyperlipidaemia with an old myocardial infarction and mild stroke; liver cirrhosis due to non-alcoholic steatohepatitis (NASH) with hypersplenism and oesophageal varices but no ascites, oedema or bleeding; and benign prostatic hypertrophy. His medications (unchanged for years) included furosemide, spironolactone, bisoprolol, rosuvastatin, alfuzosin and omeprazole. Two weeks prior, he was discharged from our department after left leg cellulitis and Streptococcus pyogenes bacteraemia responsive to parenteral clind...
Source: Postgraduate Medical Journal - March 22, 2022 Category: General Medicine Authors: Schattner, A., Dubin, I. Tags: Adverse drug reactions Source Type: research
Atrial fibrillation, liver cirrhosis, thrombosis, and bleeding: A Danish population-based cohort study
CONCLUSION: In patients with AFF, liver cirrhosis was associated with an elevated risk of ischemic stroke, venous thromboembolism, and all evaluated bleeding complications.PMID:35229067 | PMC:PMC8867136 | DOI:10.1002/rth2.12668
Source: Thrombosis and Haemostasis - March 1, 2022 Category: Hematology Authors: Emil B Riahi Kasper Adelborg Lars Pedersen S øren R Kristensen Anette T Hansen Henrik T S ørensen Source Type: research
Multimorbidity patterns and association with mortality in 0.5 million Chinese adults
CONCLUSION: Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults.PMID:35191418 | DOI:10.1097/CM9.0000000000001985
Source: Cancer Control - February 22, 2022 Category: Cancer & Oncology Authors: Junning Fan Zhijia Sun Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Dianjianyi Sun Yuanjie Pang Jun Zhang Simon Gilbert Daniel Avery Junshi Chen Zhengming Chen Jun Lyu Liming Li China Kadoorie Biobank Collaborative Group Source Type: research
