Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables: A prospective study of diagnostic accuracy
The objective was to evaluate SV and arterial pressure fluid responsiveness in liver cirrhosis patients by using dynamic preload and vascular tone variables.
DESIGN: A prospective study of diagnostic accuracy.
SETTINGS: A single-centre trial conducted from November 2013 to April 2015.
PATIENTS: Thirty-one adult patients, recipients of a living donor liver transplantat.
INTERVENTION: An intraoperative fluid challenge with 10 ml kg−1 of 0.9% normal saline.
MAIN OUTCOME MEASURES: PPV, SVV, cardiac index and systemic vascular resistance index were measured using the Pulse index Continuous cardiac system. The PVI and perfusion index were measured using the Masimo Radical 7 co-oximeter. The PPV, SVV and PVI were measured to investigate SV fluid responsiveness, and the PPV/SVV ratio, perfusion index and systemic vascular resistance index were measured to investigate arterial pressure fluid responsiveness.
RESULTS: The areas under the receiver operating characteristic curves for PPV, SVV and PVI were 0.794, 0.754 and 0.800, respectively (all P
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Cardiovascular physiology Source Type: research
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