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Condition: Cirrhosis

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How Alcohol Use Affects Health
You may have heard of Dry January, a campaign run in the U.K. by Alcohol Concern. To promote alcohol awareness, it involves (as you’ve likely gathered) completely abstaining from alcohol for the month of January. It’s a valuable campaign with noble intentions, but a minority of participants may unfortunately miss the wider point. A month of strict abstinence does lead some to drink more than they should come February 1. Remaining alcohol free for a month is an achievement which deserves to be rewarded, but compensatory drinking is not what Dry January is trying to advocate. A healthy attitude towards consumption (not ...
Source: Psych Central - February 13, 2016 Category: Psychiatry Authors: Dr. Wayne Osborne Tags: Addictions Alcoholism General Healthy Living Substance Abuse Abstinence Alcohol Abuse Alcoholic beverage Binge Drinking Drinking culture Liver disease Liver health Long-term effects of alcohol Moderation National Council on Alc Source Type: news

You Don't Need To Lose A Lot Of Weight To Start Seeing Health Benefits
This study clarifies conventional wisdom among obesity experts, who have traditionally advised patients to lose 5 to 10 percent of their body weight in order to improve blood pressure, cholesterol and blood sugar levels. But as anyone who has ever tried to lose weight can attest, there is a big difference between 5 percent and 10 percent.   "That’s a very vague, wide range," Klein said. "It’s much harder to achieve a 10 percent weight loss than it is to achieve a five percent weight loss." Klein said his study shows that even just a little bit of weight loss is enough to improve health, and that peopl...
Source: Science - The Huffington Post - February 23, 2016 Category: Science Source Type: news

Visceral Fat Triggers Heart Disease
I tell my patients to avoid drinking soda not just because they make you fat. Each sip of soda affects your health. Soda puts you at risk for health problems like metabolic syndrome. This is a collection of symptoms that can lead to diabetes, heart disease and other chronic diseases, like cancer. Soft drinks are the beverage of choice for millions of Americans. The latest research now reveals that sodas are a major cause of visceral fat — the deadliest kind of fat you can have, inflaming your tissues, rotting your blood vessels and upsetting your body chemistry. In a minute I’m going to tell you about a great healthy ...
Source: Al Sears, MD Natural Remedies - February 29, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health heart disease metabolic syndrome Visceral Fat Source Type: news

Cardiac manifestations in alcoholic liver disease
Alcoholic liver disease is the most prevalent cause of progressive liver disease in Europe. Alcoholic cirrhosis occurs in 8%–20% of cases of alcoholic liver disease. It has significant influence on cardiovascular system and haemodynamics through increased heart rate, cardiac output, decreased systemic vascular resistance, arterial pressure and plasma volume expansion. Cirrhotic cardiomyopathy is characterised by systolic and diastolic dysfunction and electrophysiological abnormalities, if no other underlying cardiac disease is present. It is often unmasked only during pharmacological or physiological stress, when com...
Source: Postgraduate Medical Journal - March 21, 2016 Category: Journals (General) Authors: Milic, S., Lulic, D., Stimac, D., Ruzic, A., Zaputovic, L. Tags: Reviews Source Type: research

Imaging of a Fatal Air Embolism from ERCP (P4.363)
CONCLUSIONS: Though most of the occurrences in relation to ERCP are portal venous air embolisms, which are absorbed spontaneously, serious and sometimes fatal complications have occurred including arterial air embolisms causing multiorgan damage including cerebral infarcts. Case history, pertinent imaging and pathological findings are discussed to bring awareness of this rare complication of ERCP and emphasize its early recognition. Disclosure: Dr. Jens has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ibrahimi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Jens, W., Lee, A., Ibrahimi, M. Tags: Cerebrovascular Case Reports Source Type: research

Point-of-Care Echocardiography Improves Assessment of Volume Status in Cirrhosis and Hepatorenal Syndrome.
Abstract The management of patients with cirrhosis along with acute kidney injury is complex and depends in large part on accurate assessment of intravascular volume status. Assessment of intravascular volume status by point-of-care echocardiography often relies solely on inferior vena cava size and variability evaluation; however, this parameter should be interpretated with an understanding of right ventricular function integrated with stroke volume and flow. Attempts to optimize intra-abdominal hemodynamics favorably are clearly problematic when physical examination findings or rudimentary assessments of central...
Source: The American Journal of the Medical Sciences - April 30, 2016 Category: Journals (General) Authors: Huggins JT, Doelken P, Walters C, Rockey DC Tags: Am J Med Sci Source Type: research

Alcoholic cardiomyopathy : The result of dosage and individual predisposition.
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Historical exa...
Source: Herz - September 3, 2016 Category: Cardiology Tags: Herz Source Type: research

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research

Apelin/APJ system: A novel promising therapy target for pathological angiogenesis.
In conclusion, the Apelin/APJ system would be a promising therapeutic target for angiogenesis-related diseases. PMID: 28025030 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - December 22, 2016 Category: Chemistry Authors: Wu L, Chen L, Li L Tags: Clin Chim Acta Source Type: research

Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition
ConclusionConcomitant narcotic use and diabetes have a compounding effect on the quality of bowel preparation prior to colonoscopy.
Source: Digestive Diseases and Sciences - December 28, 2016 Category: Gastroenterology Source Type: research

Apelin/APJ system: A novel promising therapy target for pathological angiogenesis
In conclusion, the Apelin/APJ system would be a promising therapeutic target for angiogenesis-related diseases.
Source: Clinica Chimica Acta - January 17, 2017 Category: Laboratory Medicine Source Type: research

Forced Vital Capacity Predicts Morbidity and Mortality in Adult Patients with Fontan Circulation
Due to advances in cardiology and cardiac surgery, the 15-year survival after the Fontan operation for palliation of single-ventricle congenital heart disease (CHD) is now over 90% [1,2]. However, survivors with Fontan circulation are at risk for developing long-term complications that include exercise intolerance, congestive heart failure, protein losing enteropathy, plastic bronchitis, arrhythmias, stroke, and cirrhosis, all of which contribute to the risk for hospitalization and death in long-term follow-up [2 –6].
Source: Progress in Pediatric Cardiology - January 27, 2017 Category: Cardiology Authors: Katie E. Cohen, Matthew Buelow, Jennifer Dixon, Ruta Brazauskas, Scott Cohen, Michael G. Earing, Salil Ginde Source Type: research

The risk of lower gastrointestinal bleeding in low ‐dose aspirin users
ConclusionsThe risk of LGIB was higher in low‐dose aspirin users than in aspirin nonusers in this nationwide cohort. Low‐dose aspirin, NSAIDs, steroids, SSRIs, PPIs and H2RAs were independent risk factors for LGIB.
Source: Alimentary Pharmacology and Therapeutics - April 27, 2017 Category: Drugs & Pharmacology Authors: W. ‐C. Chen, K.‐H. Lin, Y.‐T. Huang, T.‐J. Tsai, W.‐C. Sun, S.‐K. Chuah, D.‐C. Wu, P.‐I. Hsu Tags: Original Article Source Type: research

Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression.
Authors: Lee KS, Chun SY, Kwon YS, Kim S, Nam KS Abstract A high‑fat diet or high‑cholesterol diet (HCD) is a major cause of metabolic diseases, including obesity and diabetes; vascular diseases, including hypertension, stroke and arteriosclerosis; and liver diseases, including hepatic steatosis and cirrhosis. The present study aimed to evaluate the effects of deep sea water (DSW) on rats fed a HCD. DSW decreased HCD‑induced increases in total cholesterol and low‑density lipoprotein (LDL) cholesterol in the blood, and recovered high‑density lipoprotein cholesterol. In addition, DSW decreased levels of liv...
Source: Molecular Medicine Reports - April 29, 2017 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Prognostic value of perioperative assessment of plasma cardiac troponin I in patients undergoing liver transplantation.
CONCLUSION: value of cTnI level assessed 24 hours post-surgery was a reliable predictor of death following LTx with optimal cut-off value of 0.215 ng/mL. The surgery time was the most important predictor of cTnI elevation. PMID: 28455997 [PubMed - as supplied by publisher]
Source: Acta Biochim Pol - April 25, 2017 Category: Biochemistry Authors: Jankowski K, Trzebicki J, Bielecki M, Łągiewska B, Kurnicka K, Koczaj-Bremer M, Pacholczyk M, Pruszczyk P Tags: Acta Biochim Pol Source Type: research