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Insulin Regulation of Hepatic Lipid Homeostasis
Compr Physiol. 2023 Jun 26;13(3):4785-4809. doi: 10.1002/cphy.c220015.ABSTRACTThe incidence of obesity, insulin resistance, and type II diabetes (T2DM) continues to rise worldwide. The liver is a central insulin-responsive metabolic organ that governs whole-body metabolic homeostasis. Therefore, defining the mechanisms underlying insulin action in the liver is essential to our understanding of the pathogenesis of insulin resistance. During periods of fasting, the liver catabolizes fatty acids and stored glycogen to meet the metabolic demands of the body. In postprandial conditions, insulin signals to the liver to store exc...
Source: Comprehensive Physiology - June 26, 2023 Category: Physiology Authors: Kahealani Uehara Dominic Santoleri Anna E Garcia Whitlock Paul M Titchenell Source Type: research
Deep-learning CT model effective for detecting head abnormalities
A deep-learning CT model can detect head abnormalities in 17 different regions...Read more on AuntMinnie.comRelated Reading:
Deep learning plus CT helps guide head and neck cancer treatment
Using AI with prior LDCT exams improves lung nodule risk assessment
Can AI body composition analysis predict mortality risk on LDCT?
AI plus CT improves cirrhosis prediction in liver disease patients
CT radiomics can help in predicting outcomes in stroke patients
Source: AuntMinnie.com Headlines - August 22, 2023 Category: Radiology Source Type: news
Insulin Regulation of Hepatic Lipid Homeostasis
Compr Physiol. 2023 Jun 26;13(3):4785-4809. doi: 10.1002/cphy.c220015.ABSTRACTThe incidence of obesity, insulin resistance, and type II diabetes (T2DM) continues to rise worldwide. The liver is a central insulin-responsive metabolic organ that governs whole-body metabolic homeostasis. Therefore, defining the mechanisms underlying insulin action in the liver is essential to our understanding of the pathogenesis of insulin resistance. During periods of fasting, the liver catabolizes fatty acids and stored glycogen to meet the metabolic demands of the body. In postprandial conditions, insulin signals to the liver to store exc...
Source: Comprehensive Physiology - June 26, 2023 Category: Physiology Authors: Kahealani Uehara Dominic Santoleri Anna E Garcia Whitlock Paul M Titchenell Source Type: research
