Filtered By:
Condition: Osteoarthritis
This page shows you your search results in order of date. This is page number 3.
Order by Relevance | Date
Total 352 results found since Jan 2013.
Down-regulation of Jun induces senescence through destabilizing chromatin in osteoarthritis chondrocytes
CONCLUSION: Jun plays a crucial role in OA development and causes senescence by destabilizing chromatin in chondrocytes. These findings provide new insights into OA progression and suggest promising therapeutic targets.PMID:37560235 | PMC:PMC10408544
Source: American Journal of Translational Research - August 10, 2023 Category: Research Authors: Ting Xie Xunshan Ren Huangming Zhuang Fuze Jiang Yuelong Zhang Panghu Zhou Source Type: research
The regulatory role and mechanism of lncTUG1 on cartilage apoptosis and inflammation in osteoarthritis
CONCLUSIONS: In conclusion, our study clarifies the role of the ceRNA regulatory network of TUG1/miR-144-3p/DUSP1/P38 MAPK in OA cartilage injury and provides an experimental and theoretical basis for genetic engineering tools to promote articular cartilage repair.PMID:37340458 | DOI:10.1186/s13075-023-03087-7
Source: Cell Research - June 20, 2023 Category: Cytology Authors: Nan-Nan Liu Yan-Ping Huang Yu-Bao Shao Xue-Fei Fan He-Yan Sun Tao-Rong Wang Tao Yao Xiao-Yu Chen Source Type: research
Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis
CONCLUSION: Hence, our results demonstrated that knockdown of circSOD2 may serve as an intervention strategy to alleviate OA progression through modulating miR-224-5p/PRDX3 signaling axis.PMID:37312219 | DOI:10.1186/s13018-023-03880-9
Source: Cell Research - June 13, 2023 Category: Cytology Authors: Hao Li Yong Cao Chongfei Chang Wenping Huang Songchuan Su Zhenggang Peng Jiajin Zhang Source Type: research
Stevioside protects primary articular chondrocytes against IL-1 β-induced inflammation and catabolism by targeting integrin
Int Immunopharmacol. 2023 May 9;119:110261. doi: 10.1016/j.intimp.2023.110261. Online ahead of print.ABSTRACTOsteoarthritis (OA) is a common, progressive, and chronic disorder of the joints that is characterized by the inflammation and degradation of articular cartilage and is known to significantly impair quality of daily life. Stevioside (SVS) is a natural diterpenoid glycoside that has anti-inflammatory benefits. Hence, in the current research, it was hypothesized that SVS might exert anti-inflammatory effects on articular chondrocytes and alleviate cartilage degradation in mice with OA. The expression of inflammatory c...
Source: International Immunopharmacology - May 11, 2023 Category: Allergy & Immunology Authors: Junlai Wan Ziqing Zhu Zhiyi He Hua Wu Anmin Chen Wentao Zhu Peng Cheng Source Type: research
MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain
In conclusion, in the present study, it was shown that MAGL regulated synovial macrophage polarization by inhibiting mitophagy in OA.PMID:37144506 | DOI:10.3892/mmr.2023.13004
Source: Molecular Medicine - May 5, 2023 Category: Molecular Biology Authors: Chengyong Gu Mo Chen Xueyan Li Dechun Geng Chen Wang Source Type: research
