Improved pregnancy outcome in gestational diabetes mellitus patients treated with insulin aspart and metformin: a comparative study
CONCLUSION: The combination of metformin and insulin aspart in treating GDM can effectively reduce blood glucose levels, mitigate renal injury, and improve pregnancy outcome. This treatment approach presents a viable option for optimizing maternal and fetal health in GDM cases.PMID:38715802 | PMC:PMC11070366 | DOI:10.62347/NIGM4906 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Xiaojun Fan Chuan Wang Li Chen Xuehui Zhao Yongkun Wu Guangxia Zeng Source Type: research

Development and application of the Rapha < sup > ® < /sup > device for the treatment of diabetic foot ulcers
CONCLUSION: Ultimately, this study underscores TMR's vital role in advancing healthcare access and posits that academic institutions can significantly influence the creation of ethically robust, regulated, and impactful medical innovations, contributing meaningfully to global healthcare.PMID:38715803 | PMC:PMC11070364 | DOI:10.62347/YQEG3255 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Vladimir F Nogueira Adson F da Rocha Su élia Srf Rosa Ot ávio Sae Nogueira Mario Ff Rosa Source Type: research

Application of nursing intervention based on Snyder's hope theory in individuals with spinal cord injury
CONCLUSION: The implementation of nursing intervention derived from Snyder's hope theory can decrease the anxiety and depression levels, lower the occurrence of complications, enhance the hope level, increase the satisfaction rate, and improve the overall quality of life in patients with spinal cord injury.PMID:38715804 | PMC:PMC11070381 | DOI:10.62347/JFAI7888 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Jie Du Ruozhou Chen Hong Xie Source Type: research

Predictive value of serum myoglobin and lactate dehydrogenase in rhabdomyolysis-induced acute kidney injury from severe heatstroke
CONCLUSION: Serum Mb and LDH levels are elevated in RM-induced AKI following severe heatstroke, and their combination offers substantial predictive value for AKI in these patients.PMID:38715805 | PMC:PMC11070377 | DOI:10.62347/QSRI4858 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Xiaoyan Yin Wei Wang Source Type: research

Mechanism of static loading injury in human skeletal muscle cells
CONCLUSION: This model of mechanically-injured human skeletal muscle cells provides an experimental model for the clinically common skeletal muscle injury caused by static loading pressure. It may be used to study the mechanism of action of treatment methods for mechanically injured skeletal muscle.PMID:38715806 | PMC:PMC11070363 | DOI:10.62347/HCXU6226 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Yuan Yuan Hui Zhang Ya-Fang Li Xin-Na Xue Guo-Hui Zhang Hong Zhang Source Type: research

Low expression of ACOT13 predicts poor prognosis and immunotherapy outcome in ovarian cancer
CONCLUSION: High ACOT13 expression in OC is associated to a better OC outcome.PMID:38715807 | PMC:PMC11070359 | DOI:10.62347/OIQB4997 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Ting Xie Tingting Liu Lan Wu Nianhua Yi Source Type: research

Assessing the causal relationship between blood metabolites and low back pain: a Mendelian randomization study
CONCLUSION: This MR study demonstrated that four blood metabolites were causally related to LBP. It is possible to enhance the diagnosis of LBP, prognostic outcome predictions, and the personalization of therapy by analyzing novel signatures of metabolites.PMID:38715808 | PMC:PMC11070353 | DOI:10.62347/BAAW8408 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Linsong Ji Yanping Wang Tingsheng Lu Yijia Jia Lihang Wang Chunshan Luo Bing Qiu Source Type: research

Efficacy of cardiopulmonary rehabilitation nursing in enhancing pulmonary function, sleep quality, and living ability in COVID-19 patients
CONCLUSION: Application of cardiopulmonary rehabilitation nursing in COVID-19 patients can significantly improve pulmonary function, sleep quality, and overall quality of life, and relieve the inflammatory state of the patients, thereby enhancing prognosis. This approach has certain value of popularization and application.PMID:38715809 | PMC:PMC11070360 | DOI:10.62347/KYKR6707 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Hua Chen Zhuling Dai Guohua Huang Shuqin Yang Liang Qian Qiao Luo Jianjun Li Qin Su Xiaojuan Shu Xiuyan Fu Yinyan Wang Yuqing Xia Li Wang Taibing Deng Junjie Wen Source Type: research

Evolution and gene expression of matrix metalloproteinase gene family during gonadal development in < em > Scatophagus argus < /em >
CONCLUSION: The result suggested that teleost-special whole genome duplication was mainly responsible for the formation of the MMP gene family in teleosts. Expression patterns of MMP genes indicated that mmp2, 9, 14a, 15a, 15b, 16a, 17a, 23b and 24 played a vital role in testicular development while mmp28 was more important for ovarian development. Limitaion: Further studies are needed to determine their protein expressions in gonadal development and precise mechanism in gonadal differentiation. The study enhances our understanding of the MMP gene family in evolution of teleost and provides valuable insights for further re...
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Renchi Zheng Hongjuan Shi Xiaoying Ru Dongneng Jiang Yang Huang Chunhua Zhu Guangli Li Source Type: research

Integration of bulk RNA-seq and single-cell RNA-seq constructs: a cancer-associated fibroblasts-related signature to predict prognosis and therapeutic response in clear cell renal cell carcinoma
CONCLUSION: Our CRG signature holds promise in forecasting prognosis and guiding personalized treatment for patients with ccRCC.PMID:38715811 | PMC:PMC11070372 | DOI:10.62347/VCCZ1477 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Jiating Cui Xuanzhen Zhou Shuben Sun Source Type: research

Evaluation of urinary neutrophil gelatinase associated lipocalin in the early diagnosis of acute kidney injury with sepsis
CONCLUSION: uNGAL is superior to Scr for early diagnosis of AKI patients with sepsis.PMID:38715812 | PMC:PMC11070365 | DOI:10.62347/PMAL7041 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Lijuan Hu Zhiyong Zhao Source Type: research

Predictive modeling of frailty status in elderly abdominal surgery patients by preoperative quadriceps ultrasound testing
CONCLUSION: BMI and thickness of all quadriceps muscle components were significant factors affecting the frailty status of elderly patients undergoing abdominal surgery. In addition, the developed model, with excellent accuracy, offers a potential tool for preoperative risk assessment in this patient population.PMID:38715813 | PMC:PMC11070378 | DOI:10.62347/AQHH6695 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Xin Zhao Jiqing Zhang Juan Chen Peng Wang Wenbin Liu Source Type: research

Accuracy of mapping results of thoracolumbar vertebral fracture verified using finite element analysis
CONCLUSION: The results of finite element analysis further confirm the accuracy of fracture mapping and explain the distribution characteristics of fracture lines. This will provide theoretical support for the selection of clinical fracture treatment, intraoperative implants, and for a standard fracture model.PMID:38715814 | PMC:PMC11070374 | DOI:10.62347/BVDL1541 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Hui Lu Shuo Han Rong Liu Xuexiao Ma Source Type: research

Semaglutide alleviates early brain injury following subarachnoid hemorrhage by suppressing ferroptosis and neuroinflammation via SIRT1 pathway
CONCLUSIONS: Semaglutide can improve murine neurological outcomes and reduce neuronal damage against neuroinflammation and ferroptosis.PMID:38715815 | PMC:PMC11070367 | DOI:10.62347/IZGJ1332 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Lei Chen Haiting Xu Chunlei Zhang Jianqing He Yuhai Wang Source Type: research

Prognostic value of RNF113A shows a correlation with immune infiltrates in colorectal cancer
CONCLUSION: RNF113A may regulate CRC through the rRNA processing pathway and negatively correlate with the infiltration level of immune cells, serving as a prognostic biomarker for CRC.PMID:38715816 | PMC:PMC11070368 | DOI:10.62347/EUKS9325 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 8, 2024 Category: Research Authors: Minghui Chen Xiaoyu Song Huizhen Lin Wenli Cheng Source Type: research