Predictive factors for postoperative ıntensive care unit admission in pediatric patients undergoing scoliosis correction surgery
CONCLUSIONS: A smaller bodyweight percentile, neuromuscular etiology, abnormal findings in preoperative chest X-ray, additional comorbidities, and preoperative estimated risk for postoperative mechanical ventilation were among the risk factors for postoperative ICU stay. The age, height, weight, degree of the curvature, and the number of operated segments did not have an association with the postoperative outcomes.PMID:34150135 | PMC:PMC8205743 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Selcan Akesen Source Type: research

Dynamics of heart rate variability in patients with type 2 diabetes mellitus during spinal anesthesia using dexmedetomidine
Am J Transl Res. 2021 May 15;13(5):5395-5403. eCollection 2021.ABSTRACTObjective The aim of this study was to investigate the heart rate variability (HRV) in patients with Type 2 diabetes mellitus (T2DM) who underwent spinal anesthesia using dexmedetomidine for lower limb surgery.METHODS: T2DM patients were divided into two groups, namely the controlled group (HbA1c 7%) according to the glycosylated hemoglobin (HbA1c) level, and patients with non-T2DM as the normal group, 30 cases in each group. The HRV, including low-frequency (LF) power, high-frequency (HF) power, total power (TP) and LF/HF ratio, was measured 10 min bef...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Liying Ye Bo Dai Zheyou Wu Ying Hu Source Type: research

Hemodynamics and anesthetic effect of propofol combined with remifentanil in patients undergoing laparoscopic ovarian cystectomy under laryngeal mask airway anesthesia
Am J Transl Res. 2021 May 15;13(5):5404-5411. eCollection 2021.ABSTRACTOBJECTIVE: To study the effect of propofol combined with remifentanil on hemodynamics and anesthetic effect in patients undergoing laparoscopic ovarian cystectomy under laryngeal mask airway (LMA) anesthesia.METHODS: From December 2018 to December 2019, gynecological patients who underwent laparoscopic ovarian cystectomy in our hospital were chosen and randomly separated into control group (group A) and combination group (group B). In the group B, patients were anesthetized with remifentanil combined with propofol. In the group A, patients were anesthet...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yanshu Xu Jiang Wu Jili Zhao Haiping Zhang Source Type: research

LNG-IUS combined with progesterone ameliorates endometrial thickness and pregnancy outcomes of patients with early-stage endometrial cancer or atypical hyperplasia
Am J Transl Res. 2021 May 15;13(5):5412-5419. eCollection 2021.ABSTRACTOBJECTIVE: To determine the positive effect of levonorgestrel-releasing intrauterine system (LNG-IUS) combined with progesterone on endometrial thickness and pregnancy outcomes of patients with atypical endometrial hyperplasia (AEH) or early-stage endometrial cancer (EEC).METHODS: Patients with AEH or EEC admitted to our hospital were enrolled, and assigned to a control group (con group) and a combination group (com group). Patients in the con group were treated with LNG-IUS, while those in the com group were treated with LNG-IUS combined with progester...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Fang Fang Hao Xu Ling Wu Linyi Hu Ying Liu Yinnan Li Chunhua Zhang Source Type: research

The value of LncRNA SNHG5 as a marker for the diagnosis and prognosis of gastric cancer
Am J Transl Res. 2021 May 15;13(5):5420-5427. eCollection 2021.ABSTRACTOBJECTIVE: To elucidate the value of serum lncRNA SNHG5 as a marker for the diagnosis and prognosis in gastric cancer.METHODS: From January 2017 to January 2018, serum samples were collected from 50 cases of gastric cancer patients and 50 cases of benign gastrosia who underwent operations in our hospital, and 50 cases of healthy person. We detected the expression level of serum lncRNA SNHG5 in all research targets and the expression levels of LncRNA SNHG5 in the cancer adjacent tissues and cancer tissues of gastric cancer patients to analyze the relatio...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xiangying Li Yaqing Du Yunfang Wang Source Type: research

Efficacy of montmorillonite and vitamin AD combined with zinc preparation in children with diarrheal disease and its effect on inflammatory factors
Am J Transl Res. 2021 May 15;13(5):5428-5435. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of montmorillonite and vitamin AD combined with zinc preparation in children with diarrheal disease and its effect on inflammatory factors.METHODS: A total of 156 children with diarrheal diseases admitted to our hospital from January 2018 to January 2020 were enrolled and divided into two groups (n=78 for each) using random number table. The control group (CG) was treated with montmorillonite, and the observation group (OG) was additionally treated with vitamin AD and zinc. Both groups completed 7 d of treatment and ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Zhen Wang Ya Wang Yan Hu Miaomiao Chen Ting Li Source Type: research

The short- and long-term efficacies of endovascular interventions for the treatment of acute ischemic stroke patients
Am J Transl Res. 2021 May 15;13(5):5436-5443. eCollection 2021.ABSTRACTOBJECTIVE: We aimed to investigate the short- and long-term efficacies of endovascular interventional therapy in acute ischemic stroke (AIS) patients.METHODS: In this retrospective study, 94 patients with AIS were recruited and divided into a control group (n=51) that was administered intra-arterial thrombolysis and an observation group (n=43) that was administered Solitaire stent thrombectomies. The postoperative recanalization and overall response rates were recorded in both groups. The hemodynamic parameters (high shear viscosity, low shear viscosity...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xingxiu Yang Xiaohui Jia Hua Ren Hongxing Zhang Source Type: research

Effect of left or right gastric artery interventional embolization on obesity and ghrelin/leptin expression in pigs
Am J Transl Res. 2021 May 15;13(5):5444-5451. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of left or right gastric artery interventional embolization on obesity and ghrelin/leptin expression in pigs.METHODS: Thirty-two female Wuzhishan pigs aged 3-4 months were randomly divided into four groups, with eight pigs in each group: obesity + left gastric artery embolization group, obesity + right gastric artery embolization group, obesity + sham surgery group and healthy control group. The body weight and serum levels of ghrelin, leptin, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) befor...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Hui Liu Xiangying Li Rihui Chen Dingcheng Liu Chao Tong Source Type: research

The effect of electronic moxibustion combined with rehabilitation nursing on the lumbar pain and stiffness of ankylosing spondylitis patients
Am J Transl Res. 2021 May 15;13(5):5452-5459. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of electronic moxibustion combined with rehabilitation nursing on the lumbar pain and stiffness of ankylosing spondylitis patients.METHODS: Ninety-four ankylosing spondylitis patients were recruited as the study cohort and randomly assigned into a control group, which underwent rehabilitation nursing, and a research group, which underwent electronic moxibustion combined with rehabilitation nursing. The clinical effects in the two groups were compared, and the occipital-wall distances, finger-floor distances, spine mo...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xin Huan Liugeng Wu Meiyi Wang Danping Xue Feng Tian Source Type: research

Application value of UPLC-MS/MS in detecting serum concentration of anti-schizophrenic drugs in patients with mental illnes
CONCLUSIONS: Given that UPLC-MS/MS renders more accurate results in detecting the concentration of psychotropic drugs, it can be applied clinically to detect the concentration of therapeutic drugs in patients with mental illness.PMID:34150144 | PMC:PMC8205737 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Shaochang Wu Guidong Zhu Dajin Zhou Hongtao Xu Longyou Zhao Source Type: research

Effects of dezocine on PAED scale and Ramsay sedation scores in patients undergoing NUSS procedure
Am J Transl Res. 2021 May 15;13(5):5468-5475. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effects of dezocine on pediatric anesthesia emergence delirium (PAED) and Ramsay sedation scores in patients undergoing Nuss procedures (minimally invasive surgery for repairing pectus excavatum).METHODS: Altogether, 100 patients with pectus excavatum who underwent Nuss procedures in our hospital were selected and randomly divided into group A (n=50) and group B (n=50). General anesthesia was carried out for each patient, with an anaesthetic of sufentanil for group A, and dezocine plus sufentanil for group B. The visual ana...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yingjing Xia Yingying Sun Junxia Liu Source Type: research

Effects of high quality nursing in patients with lung cancer undergoing chemotherapy and related influence on self-care ability and pulmonary function
Am J Transl Res. 2021 May 15;13(5):5476-5483. eCollection 2021.ABSTRACTOBJECTIVE: To explore the effects of high quality nursing in patients with lung cancer undergoing chemotherapy and related influence on self-care ability and pulmonary function.METHODS: 108 patients with lung cancer were grouped as the control group (54 cases, received routine nursing) and the observation group (54 cases, received high quality nursing including health education, psychological nursing, diet intervention, pain nursing and complication nursing). The psychology, self-care ability, pulmonary function, quality of life and complications before...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Jing Miao Shuo Ji Sue Wang Han Wang Source Type: research

The effect of pantoprazole and somatostatin combined with thrombin in the treatment of non-esophagogastric varicosity upper gastrointestinal bleeding
Am J Transl Res. 2021 May 15;13(5):5484-5490. eCollection 2021.ABSTRACTOBJECTIVE: To explore the effect of pantoprazole and somatostatin combined with thrombin in the treatment of non-esophagogastric varicosity upper gastrointestinal bleeding (UGB) as well as its influence on serum hs-CRP and coagulation function.METHODS: From June 2016 to May 2018, patients with upper gastrointestinal hemorrhage due to non-esophagogastric varices in our hospital were selected as research subjects. After screening, they were randomly divided into the combined group (57 cases) and the control group (57 cases). After the two groups are treat...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yu Duan Ji Chen Hong Cui Cuijuan Zhao Source Type: research

The effect of comprehensive nursing on the recovery speed and prognosis of elderly colon cancer patients
Am J Transl Res. 2021 May 15;13(5):5491-5497. eCollection 2021.ABSTRACTTo explore the effect of comprehensive nursing on the recovery speed and prognosis of elderly colon cancer patients. A total of 110 elderly patients undergoing colon cancer surgery in our hospital from January 2018 to January 2020 were selected and divided into a control group (n=55, routine care) and an observation group (n=55, comprehensive nursing) according to the random number table method. The post-care stress state index score, surgical tolerance, postoperative recovery, postoperative complications, satisfaction, gastrointestinal quality of life ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Jingjing Wu Chuanling Wei Fengxia Li Xiling Wang Fang Sun Source Type: research

The relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients
This study aimed to discover the relationship between the carotid atherosclerosis ultrasound parameters and the cardiac and endothelial functions of coronary heart disease patients.METHODS: 150 patients with coronary artery disease were divided into a single-branch group (one coronary artery with stenosis> 50%), a double-branch group (two coronary arteries with stenosis> 50%), and a multi-branch group (multiple coronary arteries with stenosis> 50%) based on the severity of each patient's coronary stenosis. Meanwhile, 50 healthy volunteers who were admitted to the hospital for routine health checks were recruited a...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Qingfei Song Yanling Guo Fei Pei Xiaoyan Wang Source Type: research

Retrospective analysis on the clinical characteristics of patients who were reinfected with the Corona Virus in 2019
This study aimed to explore the clinical characteristics of 742 patients with re-current Corona Virus Disease in 2019 (COVID-19), so as to provide relevant evidence for clinical diagnosis and treatment of re-infected patients.METHODS: Altogether 742 discharged COVID-19 patients were analyzed retrospectively and were divided into re-infected patients (n=60) and non-re-infected patients (n=682) according to whether they became nucleic acid positive again after discharge. The time form leaving the hospital to re-infection and the time form the first nucleic acid negative test results to being re-infected were recorded. The cl...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yan Dong Hanlin Huang Jun Yang Liyuan Yang Source Type: research

The effect of continuing care on postoperative life quality and long-term functional recovery in elderly patients with hip fracture
Am J Transl Res. 2021 May 15;13(5):5512-5518. eCollection 2021.ABSTRACTOBJECTIVE: To apply continuing care to elderly patients with hip fracture undergoing surgery, and to explore its impact on life quality and long-term functional recovery.METHODS: This prospective study was performed in 136 elderly hip fracture patients, who were admitted to the department of orthopedics of our hospital for surgical treatment. According to the random number table, these patients were assigned to the control group and the experimental group (68 patients in each group). Patients in the control group received routine care and guidance for d...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Juan Liu Qiuyan Zhao Juan Wang Jing Zhang Juan Jiang Haoyu Wang Source Type: research

Effect of comprehensive nursing on the appearance and recovery effect of oral squamous cell carcinoma patients
Am J Transl Res. 2021 May 15;13(5):5519-5525. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of comprehensive nursing on the appearance and recovery of oral squamous cell carcinoma.METHODS: 52 patients with oral squamous cell carcinoma admitted to our hospital from February 2019 to February 2020 were selected and divided into a control group (n = 26, conventional nursing care) and an observation group (n = 26, comprehensive nursing). The postoperative hospital stay and postoperative intravenous infusion time, quality of life score, postoperative complications, nursing satisfaction, shape recovery, SAS score,...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Junli Lu Dailing Xiao Junjie Sun Junqian Huang Source Type: research

Clinical efficacy of comprehensive nursing in patients with cerebral hemorrhagic hemiplegia
Am J Transl Res. 2021 May 15;13(5):5526-5532. eCollection 2021.ABSTRACTOBJECTIVE: To explore the clinical efficacy of comprehensive rehabilitation nursing (CRN) intervention in patients with cerebral hemorrhagic hemiplegia (CHH).METHODS: A total of 102 patients with CHH admitted to our hospital were selected for the prospective study. The patients were randomly divided into the control group (n=51) and the observation group (n=51) according to the random number table method. Routine nursing was performed in the control group, while CRN was conducted in the observation group. Fugl-Meyer motor function assessment scale, acti...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Zi Wang Jieqiong Pan Li Wang Ping Chen Source Type: research

Study of the association of interferon- γ gene polymorphisms and Th1/Th2 balance in tuberculosis susceptibility
This study investigated and analyzed the association of interferon-γ (IFN-γ) gene polymorphisms and Th1/Th2 balance in tuberculosis susceptibility.METHODS: From January 2018 to January 2020, 121 tuberculosis patients that were hospitalized for initial treatment and were chosen as the pulmonary tuberculosis group, and another 80 healthy individuals with physical examination in the same period were selected as the control group. The genetic distribution of IFN-γ +874 sites in the two sets of subjects was detected by sequence-specific primer PCR (PCR-SSP), the serum IFN-γ level was detected by ELISA, a...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Qiuping Wu Yuanjiang Huang Yun Zhou Guizhong Zhou Haifeng Wu Jing He Source Type: research

Effect of implementing enhanced recovery after surgery principles in the perioperative period of pediatric inguinal hernia
Am J Transl Res. 2021 May 15;13(5):5540-5546. eCollection 2021.ABSTRACTOBJECTIVE: We aimed to investigate the effect of implementing enhanced recovery after surgery (ERAS) principles in the perioperative period of pediatric inguinal hernia (IH).METHODS: In this prospective study, 98 children undergoing surgery for IH in our hospital were randomly divided into the control group (n=49, routine nursing) and the study group (n=49, nursing care with ERAS principles). The anesthesia recovery period, time from end of surgery to first ambulation and to first anal exhaust, length of hospital stay, mental state before and after the ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yanyan Song Chunying Hu Pingping Yan Huamin Wu Hui Nie Zhangzhan Wang Yongli Chen Source Type: research

The therapeutic effects of X-ray devitalization and replantation and alcoholic devitalization and replantation in adolescent patients with lower limb osteosarcoma
Am J Transl Res. 2021 May 15;13(5):5547-5553. eCollection 2021.ABSTRACTOBJECTIVE: To compare and analyze the therapeutic effects of X-ray devitalization and replantation and alcoholic devitalization and replantation in adolescent patients with lower limb osteosarcoma.METHODS: We collected clinical data for 43 osteosarcoma patients with limb salvage treatment treated in our hospital from February 2014 to February 2018. The patients were divided into x-ray devitalization and replantation group (n=23) and alcoholic devitalization and replantation group (n=20) based on the treatment methods. The two groups were compared in ope...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Haibin Yan Bingyun Zhang Chongbin Fang Xinhui Guo Source Type: research

Effect of comprehensive nursing intervention on serum inflammatory factors and quality of life in patients with pelvic inflammatory disease
Am J Transl Res. 2021 May 15;13(5):5554-5560. eCollection 2021.ABSTRACTOBJECTIVE: To explore the improvement of quality of life of patients with pelvic inflammatory disease by comprehensive nursing intervention.METHODS: Altogether 118 patients with pelvic inflammatory disease admitted to our hospital from February 2018 to December 2019 were obtained and grouped into the control group (CG) and the experimental group (EG). The CG was given routine nursing and the EG was given comprehensive nursing intervention. The clinical efficacy, changes of serum inflammatory factors, negative emotion scores, treatment compliance and qua...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Hailing Sun Hongdi Lin Haifei Ye Source Type: research

Expression of miR-92a, miR-224 and miR-25 in non-small cell lung cancer and their correlation with clinical characteristics
Am J Transl Res. 2021 May 15;13(5):5561-5567. eCollection 2021.ABSTRACTOBJECTIVE: To analyze the correlation of the expression of microRNA-92a (miR-92a), microRNA-224 (miR-224), and microRNA-25 (miR-25) in non-small cell lung cancer with its clinical characteristics.METHODS: This prospective study was performed in 125 non-small cell lung cancer patients admitted to our hospital between January 2019 and January 2020. All patients' cancer and adjacent tissue were collected and the expression of miR-92a, miR-224, and miR-25 were detected using real-time fluorescence quantitative RT-PCR. Data were analyzed using SPSS statistic...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Hao Yuan Jiajia Su Siqin Hu Peng Wei Source Type: research

Application of regional cerebral oxygen saturation monitoring with near-infrared spectroscopy in peri-anesthesia management of elderly hypertensive patients undergoing shoulder arthroscopic surgery
Am J Transl Res. 2021 May 15;13(5):5568-5574. eCollection 2021.ABSTRACTOBJECTIVE: To explore the effect of using regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy in peri-anesthesia management of elderly hypertensive patients undergoing shoulder arthroscopic surgery.METHODS: Sixty elderly patients with hypertension undergoing shoulder arthroscopic surgery under general anesthesia were enrolled as the research objects for this prospective study, and they were randomly divided into an observation group and a control group. The observation group received bispectral index (BIS) + rScO2, whi...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Zhili Jing Di Wu Source Type: research

The effect of TACE in combination with thalidomide-mediated adjuvant therapy on the levels of VEGF and bFGF in patients with hepatocellular carcinoma
Am J Transl Res. 2021 May 15;13(5):5575-5581. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the efficacy of transcatheter arterial chemoembolization (TACE) combined with thalidomide-mediated adjuvant therapy on the expression levels of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in hepatocellular carcinoma (HCC) patients.METHODS: A prospective study was designed, by which 134 HCC patients from our hospital who underwent treatment were selected and randomly divided into an observation group and a control group, 67 participants per group. The control group was administered hepatic...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Chao Tong Hui Liu Rihui Chen Fengting Zhu Source Type: research

Clinical characteristics and risk factors of patients with flupirtine-induced liver cirrhosis complicated with upper gastrointestinal bleeding
Am J Transl Res. 2021 May 15;13(5):5582-5588. eCollection 2021.ABSTRACTOBJECTIVE: To investigate clinical characteristics and risk factors of patients with Flupirtine-induced liver cirrhosis complicated with upper gastrointestinal bleeding.METHODS: A total of 116 patients with liver cirrhosis admitted to our hospital from July 2018 to July 2019 were selected and divided into bleeding group (liver cirrhosis complicated with upper gastrointestinal bleeding, n = 71) and non-bleeding group (liver cirrhosis, n = 45). The clinical data of patients in the two groups were collected, including general data, liver function, urinalys...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Mengjun Zhang Si Huang Na Ye Xuehong Wang Source Type: research

Effect of traditional Chinese medicine nursing on postoperative patients with gastric cancer and its impact on quality of life
Am J Transl Res. 2021 May 15;13(5):5589-5595. eCollection 2021.ABSTRACTOBJECTIVE: To explore the effect of traditional Chinese medicine (TCM) nursing on postoperative patients with gastric cancer and its impact on quality of life.METHODS: According to the random number table method, 103 patients with gastric cancer were divided into observation group (n=52, TCM nursing) and control group (n=51, routine nursing). The postoperative recovery of gastrointestinal function, the scores of mental states, inflammatory index, self-esteem scale (SES) and quality of life score (generic quality of life inventory-74 scale, GQOLI-74 scal...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yi Zhang Xueyan Wang Haixia Yang Source Type: research

Metformin combined with insulin aspart for ameliorating blood glucose levels and maternal and neonatal outcomes in women with gestational diabetes mellitus and chronic hypertension
Am J Transl Res. 2021 May 15;13(5):5596-5602. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of metformin combined with insulin aspart on blood glucose levels and maternal and neonatal outcomes in women with gestational diabetes mellitus (GDM) accompanied by chronic hypertension (CH).METHODS: A prospective study was conducted on 112 women with GDM and CH. The patients were divided into the control group and the observation group according to a random number table method, with 56 patients in each group. The control group received injections of insulin aspart based on blood pressure control, and the observatio...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Wei Wang Yanchun Fan Qun Lin Source Type: research

Evaluation of the effect of ultrasound interventional injection of cisplatin in the treatment of liver cancer
Am J Transl Res. 2021 May 15;13(5):5603-5609. eCollection 2021.ABSTRACTOBJECTIVE: To evaluate the effect of ultrasound interventional injection of cisplatin in the treatment of hepatocellular carcinoma (HCC).METHODS: 68 patients with HCC admitted to our hospital from February 2016 to February 2018 were enrolled. According to the different treatment methods, they were divided into a study group and a control group. The control group was treated with hepatic artery embolization chemotherapy (n=34), the study group adopted interventional ultrasound injection of cisplatin (n=34). The clinical treatment effects of the two group...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Tao Zhang Shengkai Cheng Jianbo Li Yangyang Shang Mingyou Zheng Source Type: research

The effect of EBN combined with integrated hierarchical accountability nursing on patients with severe pneumonia
Am J Transl Res. 2021 May 15;13(5):5610-5616. eCollection 2021.ABSTRACTOBJECTIVE: To explore the effects of evidence-based nursing (EBN) combined with integrated hierarchical accountability nursing on patients with severe pneumonia (SP).METHODS: 72 SP patients admitted to our hospital from March 2019 to March 2020 were recruited as the study cohort and randomly divided into control group (36 patients) or research group (36 patients). The control group underwent conventional nursing, and the research group underwent EBN combined with integrated hierarchical accountability nursing plus. The patients' respiratory function, in...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Meiqin Wang Jing Li Wei Li Huichao Tian Xinyun Kang Source Type: research

Changes and significance of serum CXCL-16, GDF-15, PLA-2 levels in patients with cerebral infarction
Am J Transl Res. 2021 May 15;13(5):5617-5622. eCollection 2021.ABSTRACTOBJECTIVE: To explore the changes and significance of serum CXC chemokine ligand 16 (CXCL-16), growth differentiation factor 15 (GDF-15) and lipoprotein-related phospholipase A2 (PLA-2) levels in patients with cerebral infarction.METHODS: A total of 87 patients with cerebral infarction between August 2019 and May 2020 in our hospital were selected as the disease group, and 50 healthy patients were selected as the healthy control group. Enzyme-linked immunosorbent assay was used to detect serum CXCL-16, GDF-15, PLA-2 expression levels in all subjects. A ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xiqi Liu Source Type: research

Effects of continuous nursing based on WeChat platform on the functional recovery and quality of life in elderly patients after total hip arthroplasty
Am J Transl Res. 2021 May 15;13(5):5623-5628. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effects of continuous nursing (CN) based on WeChat platform on the functional recovery and quality of life (QOL) in elderly patients after total hip arthroplasty (THA).METHODS: A prospective study was performed on selected 124 patients undergoing THA in Orthopedics and Traumatology Department. According to the random number method, the patients were divided into control group (CN, n=62) and observation group (CN based on WeChat platform, n=62). Hip joint function before and after intervention, postoperative complications an...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Juan Liu Qiuyan Zhao Juan Wang Jing Zhang Juan Jiang Haoyu Wang Source Type: research

Diagnostic value of nuclear medicine imaging and ultrasonography in subacute thyroiditis
CONCLUSION: Both nuclear medicine imaging and ultrasonography can provide clinical guidance for diagnosis and treatment of subacute thyroiditis.PMID:34150168 | PMC:PMC8205701 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Liankun Zhuo Yunlei Nie Lixia Ma Lei Shen Xiao Zhou Fang Li Source Type: research

Effect of acupuncture on sleep quality and neurological function in stroke patients with sleep apnea syndrome
Am J Transl Res. 2021 May 15;13(5):5635-5640. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the effect of acupuncture on sleep quality and neurological function in stroke patients with sleep apnea syndrome (SAS).METHODS: In this prospective study, a total of 88 stroke patients with SAS were randomized into two groups: observation group (44 cases; patients received the western medicine treatment combined with acupuncture) and control group (44 cases; patients were given western medicine treatment only). All patients in both groups were treated for three weeks. The clinical efficacy, sleep quality, apnea-hypopnea index ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Peng Zhang Lingsu Cheng Qian Tian Guang Chen Chao Chen Junfeng Xu Source Type: research

Application of evidence-based nursing in patients with acute myocardial infarction complicated with heart failure
Am J Transl Res. 2021 May 15;13(5):5641-5646. eCollection 2021.ABSTRACTOBJECTIVE: To explore the application of evidence-based nursing (EBN) in patients with acute myocardial infarction (AMI) complicated with heart failure.METHODS: A total of 76 patients with acute myocardial infarction complicated with heart failure after Percutaneous Transluminal Coronary Intervention (PCI) were admitted to the Department of Cardiology of our hospital from April 2018 to October 2019 and randomly divided into the control group and the experimental group, with 38 patients in each group. The control group received routine nursing and the ex...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yanyun Zhou Xuan Wang Shanshan Lan Li Zhang Guixia Niu Guiqin Zhang Source Type: research

Comprehensive nursing intervention combined with early activityactivity applied in ventilator-associated pneumonia and its influence on blood gas index
Am J Transl Res. 2021 May 15;13(5):5647-5652. eCollection 2021.ABSTRACTOBJECTIVE: To study the application effect of comprehensive nursing combined with early activityactivity in patients with ventilator-associated pneumonia (VAP) and its influence on blood gas indexes of patients.METHODS: 100 patients with VAP admitted to our hospital from February 2018 to November 2019 were randomly selected and divided into control group and experimental group, with 50 patients in each group. Patients in the control group received routine nursing intervention with early activity, and patients in the experimental group received comprehen...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Zhen Li Liying Xu Yunxia Wang Haipeng Gao Source Type: research

Combined detection of ACL and β2-GP1 in diagnosis of adverse pregnancy
Am J Transl Res. 2021 May 15;13(5):5653-5658. eCollection 2021.ABSTRACTOBJECTIVE: To illustrate the significance of combined detection of anti cardiolipin (ACL) and anti-β2-glycoprotein 1 (β2-GP1) in the diagnosis of adverse pregnancy.METHODS: 60 postnatal women with adverse pregnancy presented to our hospital from March 2019 to March 2020 were enrolled as the experimental group, and 60 postnatal women with normal delivery in the same period were selected as the control group. The levels of ACL, β2-GP1 were measured to analyze the significance of the integrated detection in the diagnosis of adverse pregnancy...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Wei Zhang Dong Wang Weixin Yuan Shuiping Yao Source Type: research

The correlation study on homocysteine, blood lipids and blood glucose levels in patients with cerebral infarction
Am J Transl Res. 2021 May 15;13(5):5659-5664. eCollection 2021.ABSTRACTPURPOSE: To explore the correlation of changes in homocysteine (HCY) l, blood lipids and blood glucose levels in patients with cerebral infarction.METHODS: 120 patients with cerebral infarction admitted to our hospital from February 2018 to February 2020 were selected as the experimental group, and 120 healthy volunteers in the same period were selected as the control group. The blood pressure and the homocysteine, blood lipids, blood glucose levels were compared; the experimental group was subdivided into single cerebral infarction group, combined diab...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Wen-Ling Li Hua Sang Xin Xu Yuan-Yuan Zhang Jie Gao Bo-Hua Chen Xiang-Ying Meng Source Type: research

The correlation between the vitamin A, D, and E levels and recurrent respiratory tract infections in children of different ages
CONCLUSION: Monitoring the serum vitamin A and D levels helps determine the disease severity, and the supplementation of adequate vitamin A and D through diet or drugs is of great help in treating RRTIs.PMID:34150174 | PMC:PMC8205845 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Wenqiu Tian Wenxia Yi Jing Zhang Mei Sun Rongrong Sun Zhixin Yan Source Type: research

A comparison of modified laparoscopic uterine suspension and vaginal hysterectomy with sacrospinous ligament fixation for treating pelvic organ prolapse
Am J Transl Res. 2021 May 15;13(5):5672-5678. eCollection 2021.ABSTRACTOBJECTIVES: To compare the efficacy and adverse events between modified laparoscopic uterine suspension and vaginal hysterectomy and sacrospinous ligament fixation.METHODS: The study reviewed the clinical data of 50 postmenopausal patients who underwent modified laparoscopic uterine suspension (the hysteropexy group) and 50 patients who underwent vaginal hysterectomy with sacrospinous ligament fixation (the hysterectomy group) conducted by the same group of surgeons (2018.1-2019.6) retrospectively. We compared the two groups' baseline characteristics, p...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Hongxia Zhu Yixuan Sun Xuan Zheng Source Type: research

Surgical clipping and endovascular embolization for senile patients with posterior communicating artery aneurysms complicated with oculomotor nerve palsy
Am J Transl Res. 2021 May 15;13(5):5679-5684. eCollection 2021.ABSTRACTOBJECTIVE: To explore the clinical effect of the surgical clipping and endovascular embolization for senile patients with posterior communicating artery aneurysms (PComA) complicated with oculomotor nerve palsy (ONP) and their neurological recovery.METHODS: A total of 96 senile patients with PComA complicated with ONP admitted to our hospital from May 2018 to May 2019 were selected and assigned into the experimental group and the control group according to the randomization method, with 48 cases in each group. The patients in the control group underwent...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xue Yang Chizhong Zhou Ling Liang Source Type: research

Effect of indwelling time of double J tube on infected ureteral calculi and the distribution of pathogenic characteristics in diabetics
CONCLUSION: The indwelling time of the double J tube has no significant effect on the effectiveness and safety in diabetic patients with infected UC. It is necessary to reduce the indwelling time and implement targeted stone surgery.PMID:34150177 | PMC:PMC8205665 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Wenxian Xie Suchuan Zhang Xiaobin Li Yuejiang Liu Jian Yang Ping Liu Ke Zeng Source Type: research

Effect of systematic nursing on patients with dysfunctional uterine bleeding and rehabilitation
Am J Transl Res. 2021 May 15;13(5):5691-5696. eCollection 2021.ABSTRACTPurpose: To study the effect of systematic nursing on patients with dysfunctional uterine bleeding and rehabilitation. Methods: 98 patients who were treated in our hospital for dysfunctional uterine bleeding from May 2017 to May 2019 were selected, and were divided into a control group (n=49, conventional nursing) and an observation group (n=49, systematic nursing) according to the random number table method. The curative effect, uterine bleeding time, normalization time of biochemical index recovery, psychologic status, quality of life, and nursing sat...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Yan Sun Haiyan Luo Source Type: research

Dynamic and conventional electrocardiograms for diagnosing arrhythmic coronary atherosclerotic heart disease: a comparative analysis
This study aims to compare the clinical effects of dynamic electrocardiograms (ECGs) and conventional ECGs in the diagnosis of arrhythmic coronary atherosclerotic heart disease.METHODS: Fifty patients with arrhythmic coronary atherosclerotic heart disease admitted to our hospital from January 2019 to January 2020 were recruited as the study cohort. All the 50 patients were first diagnosed using conventional ECGs, and then they were diagnosed using 24-hour dynamic ECGs. The results of the conventional ECG diagnoses were taken as the control group, and the results of 24-hour dynamic ECG diagnoses were taken as the experiment...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Xiaoxing Hu Huiping Tong Source Type: research

Knocking down LINC01116 can inhibit the regulation of TGF- β through miR-774-5p axis and inhibit the occurrence and development of glioma
CONCLUSION: LncRNA LINC01116 acts as an oncogene and promotes TGF-β1 mediated proliferation and metastasis by acting as competitive endogenous RNA (ceRNA) in glioma.PMID:34150180 | PMC:PMC8205728 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Jinfeng Lou Pengfei Wang Keliang Chang Genwei Wang Xiaoteng Geng Yang Wu Wanhong Zhang Guangming Niu Source Type: research

Integrated analysis identifies S100A16 as a potential prognostic marker for pancreatic cancer
CONCLUSION: S100A16 is a potential independent prognostic marker and immunotherapy target for PC. Mechanistically, S100A16 potentially affects prognosis by extensive immunosuppression, including the inhibition of the anti-tumor immune response of CD8+ T cells.PMID:34150181 | PMC:PMC8205789 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Tian Chen De-Meng Xia Chao Qian Shan-Rong Liu Source Type: research

Serum galectin-3 level as a marker for diagnosis and prognosis of neonatal necrotising enterocolitis: a cohort study
CONCLUSION: GAL-3 is a useful marker for diagnosing and prognosis of neonatal necrotising enterocolitis.PMID:34150182 | PMC:PMC8205674 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Chuan Zhou Li Li Xiaoxia Feng Dandan Wang Yuanyuan Liu Jingjing Li Hong Song Baisui Feng Source Type: research

The efficiency of internal fixation with bone grafting at docking sites after bone transport for treatment of large segmental tibial bone defects
Am J Transl Res. 2021 May 15;13(5):5738-5745. eCollection 2021.ABSTRACTOBJECTIVE: To investigate the efficiency of internal fixation with bone grafting after bone transport for treatment in large-segment bone defects of the lower-limbs.METHODS: This prospective study recruited 100 patients with lower limb tibial segmental bone defects, and based on a random number table they were divided into a control group (n=50, simple bone transport surgery) or an observation group (n=50, internal fixation with bone grafting at docking site after bone transport). The fracture healing time, bone healing index, external fixation time in ...
Source: American Journal of Translational Research - June 21, 2021 Category: Research Authors: Maimaiti Xiayimaierdan Jinyong Huang Chenchen Fan Feiyu Cai Yusupu Aihemaitijiang Zengru Xie Source Type: research

Sequential treatment of phenethyl isothiocyanate increases sensitivity of Temozolomide resistant glioblastoma cells by decreasing expression of MGMT via NF- κB pathway [Retraction]
Am J Transl Res. 2021 May 15;13(5):5746. eCollection 2021.ABSTRACT[This retracts the article on p. 696 in vol. 11, PMID: 30899372.].PMID:34150184 | PMC:PMC8205778 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - June 21, 2021 Category: Research Source Type: research