The effects of vasopressin injection technique on ovarian reserve in laparoscopic cystectomy of bilateral ovarian endometrioma: a retrospective cohort study
CONCLUSION: VIT effectively protected ovarian reserve in laparoscopic cystectomy of bilateral ovarian endometrioma.PMID:35559399 | PMC:PMC9091081 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Lingli Xin Mei Ye Lina Yang Ling Chen Lirong Wang Qingxiang Hou Source Type: research

Association between chronic kidney disease and cancer including the mortality of cancer patients: national health and nutrition examination survey 1999-2014
CONCLUSION: CKD is significantly associated only with genitourinary cancer among different types of cancer. CKD is an independent risk factor for survival in cancer patients, regardless of the type of cancer. Monitoring and maintaining the renal function of cancer patients is essential for prolonging their life.PMID:35559400 | PMC:PMC9091102 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Kanglin Guo Zufeng Wang Ran Luo Yichun Cheng Shuwang Ge Gang Xu Source Type: research

Endoscopic- versus x-ray-guidance for placement of nasojejunal tubes in critically ill patients: a systematic review and meta-analysis of randomized controlled trials
Am J Transl Res. 2022 Apr 15;14(4):2134-2146. eCollection 2022.ABSTRACTNasojejunal tubes (NJTs) are increasingly used in critically ill patients. NJT insertion with endoscopic- or x-ray-guidance can be achieved with success rates above 90%. This systematic review and meta-analysis of randomized controlled trials (RCTs) compares the efficiency and safety of these two methods in critically ill patients. We searched Chinese and English databases for RCTs comparing endoscopy- and x-ray-guided NJT placement published up to July 5, 2021. Meta-analyses were performed using RevMan5 software to compute mean differences (MDs) and od...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Guanzhen Lu Qin Xiang Sha Wang Mingyue Pan Xu Xiang Yanling Yang Xinyan Shi Source Type: research

Trend analysis of drug overdose deaths before and during the COVID-19 pandemic
Am J Transl Res. 2022 Apr 15;14(4):2685-2688. eCollection 2022.ABSTRACTData from a single state indicated there was an increase in opioid overdose related emergency services during the COVID-19 pandemic. The current study examined the provisional rolling 12-month drug overdose deaths between January 2019 and October 2021 at the national, state, and specific-drug levels, to identify trends in drug-overdose deaths before and during the COVID-19 pandemic. The trend in provisional U.S. drug overdose deaths accelerated at the beginning of the pandemic (December 2019). This acceleration slowed in the middle of pandemic (October ...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Cynthia Chen Shiqian Shen Source Type: research

Comparison of Intra- and postoperative effectiveness of erector spinae plane block and patient controlled analgesia in patients undergoing coronary artery bypass grafting surgery
Am J Transl Res. 2022 Apr 15;14(4):2469-2479. eCollection 2022.ABSTRACTThe aim of our study was to compare bilateral erector spinae plane block (ESPB) efficacy on pain management with patient controlled analgesia (PCA) during the perioperative period in patients scheduled for coronary artery bypass grafting (CABG). After ethics committee approval (2019-7/31 dated 09.04.2019) from the Bursa Uludağ University Medical Trials Ethics Committee, (https://uludag.edu.tr/buuetikkurulu) ASA II-III, 50 patients aged between 18-80 years were included. They were randomly divided into two groups, ESPB (n=25) and control (n=25). In the ...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Lale O ğur Selcan Akesen Suna G ören İrem İris Kan Elif Ba şağan Moğol Alp Gurbet Source Type: research

The Haoqin-Huaban formula alleviates UVB-induced skin damage through HOXA11-AS-mediated stabilization of EZH2
In this study, we found that administration of HQHB inhibited, in a dose-dependent manner, UVB-induced skin damage by eliminating oxidative stress. HQHB was found to upregulate HOXA11-AS expression by activating HIF-1α. Furthermore, HOXA11-AS stabilized the EZH2 protein by inhibiting its ubiquitination and proteasomal degradation. Consequently, rescue assays demonstrated that HOXA11-AS promoted proliferation and inhibited apoptosis in HaCaT cells by reducing oxidative stress. Taken together, our results help to elucidate the function and regulatory mechanism of HQHB in reducing UVB-induced skin damage.PMID:35559404 | PMC:...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Xuying Xu Siyi Wang Dongmei Zhou Jianhua Qu Cang Zhang Yichuan Xu Liyun Sun Source Type: research

The curative effect of Shenfu-injection in the treatment of burn sepsis and its effect on the patient's immune function, HMGB, and vWF
CONCLUSION: SFI can effectively improve the immunity of patients with burn-injured sepsis, reduce the expression of cytokines such as HMGB and vWF, and is of great help for the improvement of clinical prognosis.PMID:35559405 | PMC:PMC9091091 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Chuanzhen Xu Yongfu Xia Zhuting Jia Shasha Wang Tongzhen Zhao Liqiang Wu Source Type: research

Overexpression of galectin2 (LGALS2) predicts a better prognosis in human breast cancer
CONCLUSION: In conclusion, LGALS2 has potential as a valuable biomarker for envisaging a satisfactory prognosis in patients with breast tumours, particularly those with luminal and basal B types, all stages and grade III tumours.PMID:35559406 | PMC:PMC9091085 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Mandika Chetry Adheesh Bhandari Ruiling Feng Xinming Song Pintian Wang Jing Lin Source Type: research

Comparison of clinical efficacy and safety of transvaginal natural endoscopic surgery and transumbilical single port laparoscopy surgery for endometrial cancer
CONCLUSION: Transvaginal natural cavity endoscopy had better surgical results with faster postoperative recovery and higher safety compared with TSPLS, making it valuable in clinical application and worthy of further popularization.PMID:35559407 | PMC:PMC9091124 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Guna He Lingyu Liu Xiaomei Liu Hui Guo Lingling Chen Rongzi Li Source Type: research

Effects of total laparoscopic hysterectomy on the clinical outcomes of patients with uterine fibroids
CONCLUSIONS: TLH is a feasible and safe alternative than traditional TAH for UFs, as it can effectively improve patients' sex hormone levels and QOL, and reduce the incidence of complications, which is worthy of clinical promotion.PMID:35559408 | PMC:PMC9091122 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Lang Zheng Dan Liu Chunyan Hu Source Type: research

Emerging role of epigenetic regulations in periodontitis: a literature review
Am J Transl Res. 2022 Apr 15;14(4):2162-2183. eCollection 2022.ABSTRACTPeriodontitis is mainly initiated by periodontal pathogens including Porphyromonas gingivalis, and bad living habits such as smoking aggravate its incidence and severity. The development of periodontitis is closely related to the host's immune responses and the secretion of various cytokine networks. Moreover, periodontitis has an important connection with the development of systemic diseases. Recently, epigenetics which is a fast-developing hot research area has provided new insights into the research of various diseases including periodontitis. Epigen...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Jing Huang Yi Zhou Source Type: research

Research on antibody changes and nucleic acid clearance in COVID-19 patients treated with convalescent plasma
CONCLUSIONS: The application of convalescent plasma significantly increases the antibody content in severe and critical inpatients, effectively enhances immune function, accelerates the clearance of virus and the nucleic acid negative conversion rate, and significantly promotes early improvement in COVID-19 patients.PMID:35559410 | PMC:PMC9091113 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Li Duan Yudi Xie Qiang Wang Xianli Sun Wenlong Guan Jun Xu Zhiqiang Lin Quan Wang Ying Qin Chi Zhang Yuanda Li Xiaojuan Qu Ling Li Jianping Li Guoyue Lin Source Type: research

LINC01272 activates epithelial-mesenchymal transition through miR-153-5p in Crohn's disease
CONCLUSION: LINC01272 activated the epithelial-mesenchymal transition through miR-153-5p in CD.PMID:35559411 | PMC:PMC9091119 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Lin Fang Mengcheng Hu Fei Xia Wenxia Bai Source Type: research

Factors influencing quality of life and work of male nurses in Hainan Province: logistic regression analysis
CONCLUSION: Male nurses in Hainan Province mostly worked in departments with high work intensity and pressure, and the overall quality of life, social support and job satisfaction were significantly lower than those of female nurses. Therefore, psychological guidance for male nurses should be strengthened, the salary of male nurses should be increased, higher social support should be provided, to reduce job burnout and thus improve their quality of life.PMID:35559412 | PMC:PMC9091086 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Yan Zou Haiyan Wang Yedan Chen Hai Xie Yingyao Chen Guangwei Wang Source Type: research

Changes in transepithelial electrical resistance and intracellular ion concentration in TGF- β-induced epithelial-mesenchymal transition of retinal pigment epithelial cells
CONCLUSION: TGF-β1 and TGF-β2 disrupted the ARPE-19 cell monolayer, disturbed TJs integrity, downregulated TEER values, and changed intracellular ion permeability. These findings might help further understand the EMT of RPE cells during PVR.PMID:35559413 | PMC:PMC9091112 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Minli Wang Jiayi Wei Hui Li Fang Wang Source Type: research