Emerging role of epigenetic regulations in periodontitis: a literature review
Am J Transl Res. 2022 Apr 15;14(4):2162-2183. eCollection 2022.ABSTRACTPeriodontitis is mainly initiated by periodontal pathogens including Porphyromonas gingivalis, and bad living habits such as smoking aggravate its incidence and severity. The development of periodontitis is closely related to the host's immune responses and the secretion of various cytokine networks. Moreover, periodontitis has an important connection with the development of systemic diseases. Recently, epigenetics which is a fast-developing hot research area has provided new insights into the research of various diseases including periodontitis. Epigen...
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Jing Huang Yi Zhou Source Type: research

Research on antibody changes and nucleic acid clearance in COVID-19 patients treated with convalescent plasma
CONCLUSIONS: The application of convalescent plasma significantly increases the antibody content in severe and critical inpatients, effectively enhances immune function, accelerates the clearance of virus and the nucleic acid negative conversion rate, and significantly promotes early improvement in COVID-19 patients.PMID:35559410 | PMC:PMC9091113 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Li Duan Yudi Xie Qiang Wang Xianli Sun Wenlong Guan Jun Xu Zhiqiang Lin Quan Wang Ying Qin Chi Zhang Yuanda Li Xiaojuan Qu Ling Li Jianping Li Guoyue Lin Source Type: research

LINC01272 activates epithelial-mesenchymal transition through miR-153-5p in Crohn's disease
CONCLUSION: LINC01272 activated the epithelial-mesenchymal transition through miR-153-5p in CD.PMID:35559411 | PMC:PMC9091119 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Lin Fang Mengcheng Hu Fei Xia Wenxia Bai Source Type: research

Factors influencing quality of life and work of male nurses in Hainan Province: logistic regression analysis
CONCLUSION: Male nurses in Hainan Province mostly worked in departments with high work intensity and pressure, and the overall quality of life, social support and job satisfaction were significantly lower than those of female nurses. Therefore, psychological guidance for male nurses should be strengthened, the salary of male nurses should be increased, higher social support should be provided, to reduce job burnout and thus improve their quality of life.PMID:35559412 | PMC:PMC9091086 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Yan Zou Haiyan Wang Yedan Chen Hai Xie Yingyao Chen Guangwei Wang Source Type: research

Changes in transepithelial electrical resistance and intracellular ion concentration in TGF- β-induced epithelial-mesenchymal transition of retinal pigment epithelial cells
CONCLUSION: TGF-β1 and TGF-β2 disrupted the ARPE-19 cell monolayer, disturbed TJs integrity, downregulated TEER values, and changed intracellular ion permeability. These findings might help further understand the EMT of RPE cells during PVR.PMID:35559413 | PMC:PMC9091112 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - May 13, 2022 Category: Research Authors: Minli Wang Jiayi Wei Hui Li Fang Wang Source Type: research