Filtered By:
Infectious Disease: Parasitic Diseases
This page shows you your search results in order of date. This is page number 5.
Order by Relevance | Date
Total 613 results found since Jan 2013.
Stem cell factor/mast cell/CCL2/monocyte/macrophage axis promotes Coxsackievirus B3 myocarditis and cardiac fibrosis by increasing Ly6C < sup > high < /sup > monocyte influx and fibrogenic mediators production
Immunology. 2022 Jul 31. doi: 10.1111/imm.13556. Online ahead of print.ABSTRACTMast cells (MCs), central players in allergy and parasitic infections, play key roles in inflammation and fibrosis. Here, the impact of MCs on the progression of Coxsackievirus B3 (CVB3)-induced viral myocarditis (VMC) and fibrosis was investigated using MC-deficient KitW-sh mice. Viral titres, cellular infiltrates and heart pathologies were evaluated and compared with wild-type (WT) mice during acute CVB3 infection of C57BL/6 mice. CVB3 infection induced an increased accumulation and degranulation of MCs in the hearts of mice during acute infec...
Source: Immunology - September 2, 2022 Category: Allergy & Immunology Authors: Yuan Luo Hongkai Zhang Jie Yu Lin Wei Min Li Wei Xu Source Type: research
TSLP, IL-33, and IL-25: not just for allergy and helminth infection
The release of cytokines from epithelial and stromal cells is critical for the initiation and maintenance of tissue immunity. Three such cytokines, TSLP, IL-33, and IL-25, are important regulators of type 2 immune responses triggered by parasitic worms and allergens. In particular, these cytokines activate group 2 innate lymphoid cells (ILC2s), Th2 cells, and myeloid cells that drive hallmarks of type 2 immunity. However, emerging data indicates that these tissue-associated cytokines are not only involved in canonical type 2 responses, but are also important in the context of viral infections, cancer, and even homeostasis.
Source: Journal of Allergy and Clinical Immunology - July 18, 2022 Category: Allergy & Immunology Authors: Alison G. Stanbery, Shuchi Smita, Jakob von Moltke, Elia D. Tait Wojno, Steven F. Ziegler Source Type: research
From the Pages of AllergyWatch
For this edition of From the Pages of AllergyWatch, I've chosen articles from the May-June 2022 AllergyWatch focusing on food allergies, the theme of this month's Annals. The first article, with comments from Dr. Lee, presents data from South Africa that alpha-gal allergy can be associated with parasites. The next article, with comments from Dr. Hernandez-Trujilio, reports improved outcomes in patients with EoE managed in multidisciplinary clinics. The last article, with comments from Dr. Lee, reports the use of an amino acid-based formula including synbiotics on infants with cow's milk allergy.
Source: Annals of Allergy, Asthma and Immunology - July 14, 2022 Category: Allergy & Immunology Authors: Stanley M. Fineman, Gerald B. Lee, Vivian Hernandez-Trujillo Tags: Special Series Source Type: research
Human IgE mAbs identify major antigens of parasitic worm infection
Much of our understanding of the targets of IgE comes from studies of allergy, though little is known about the natural immunogenic targets seen after parasitic worm infections.
Source: Journal of Allergy and Clinical Immunology - June 24, 2022 Category: Allergy & Immunology Authors: Azadeh Hadadianpour, Jacob Daniel, Jian Zhang, Benjamin W. Spiller, Asta Makaraviciute, Åsa M. DeWitt, Heather S. Walden, Robert G. Hamilton, R. Stokes Peebles, Thomas B. Nutman, Scott A. Smith Source Type: research
Human IgE mAbs Identify Major Antigens of Parasitic Worm Infection
This is the first description of the dominant antigens targeted by the IgE antibody response during human parasitic worm infection.
Source: Journal of Allergy and Clinical Immunology - June 24, 2022 Category: Allergy & Immunology Authors: Azadeh Hadadianpour, Jacob Daniel, Jian Zhang, Benjamin W. Spiller, Asta Makaraviciute, Åsa M. DeWitt, Heather S. Walden, Robert G. Hamilton, R. Stokes Peebles, Thomas B. Nutman, Scott A. Smith Source Type: research
Computer-Assisted Discovery of Alkaloids with Schistosomicidal Activity
Curr Issues Mol Biol. 2022 Jan 15;44(1):383-408. doi: 10.3390/cimb44010028.ABSTRACTSchistosomiasis is a chronic parasitic disease caused by trematodes of the genus Schistosoma; it is commonly caused by Schistosoma mansoni, which is transmitted by Bioamphalaria snails. Studies show that more than 200 million people are infected and that more than 90% of them live in Africa. Treatment with praziquantel has the best cost-benefit result on the market. However, hypersensitivity, allergy, and drug resistance are frequently presented after administration. From this perspective, ligand-based and structure-based virtual screening (...
Source: Current Issues in Molecular Biology - June 20, 2022 Category: Molecular Biology Authors: Renata Priscila Barros de Menezes J éssika de Oliveira Viana Eugene Muratov Luciana Scotti Marcus Tullius Scotti Source Type: research
Identification of excretory and secretory proteins from Haemonchus contortus inducing a Th9 immune response in goats
This study represents a proteomics-guided investigation of the interactions between Th9 cells and HcESPs. It provides a new way to explore immunostimulatory antigens among HcESPs and identifies candidates for immune-mediated prevention ofH. contortus infection.
Source: Veterinary Research - May 21, 2022 Category: Veterinary Research Source Type: research
Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations
Mol Biol Evol. 2022 May 10:msac097. doi: 10.1093/molbev/msac097. Online ahead of print.ABSTRACTHighly diversified astigmatic mites comprise many medically important human household pests such as house dust mites causing approximately 1-2% of all allergic diseases globally; however, their evolutionary origin and diverse lifestyles including reversible parasitism have not been illustrated at the genomic level, which hampers allergy prevention and our exploration of these household pests. Using six high-quality assembled and annotated genomes, this study not only refuted the monophyly of mites and ticks, but also thoroughly e...
Source: Mol Biol Cell - May 10, 2022 Category: Molecular Biology Authors: Qing Xiong Angel Tsz-Yau Wan Xiaoyu Liu Cathy Sin-Hang Fung Xiaojun Xiao Nat Malainual Jinpao Hou Lingyi Wang Mingqiang Wang Kevin Yi Yang Yubao Cui Elaine Lai-Han Leung Wenyan Nong Soo-Kyung Shin Shannon Wing-Ngor Au Kyoung Yong Jeong Fook-Tim Chew Jerom Source Type: research
