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Infectious Disease: Parasitic Diseases

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Total 613 results found since Jan 2013.

Type 2 immunity in the brain and brain borders
Cell Mol Immunol. 2023 Jul 10. doi: 10.1038/s41423-023-01043-8. Online ahead of print.ABSTRACTRecent research in neuroimmunology has revolutionized our understanding of the intricate interactions between the immune system and the central nervous system (CNS). The CNS, an "immune-privileged organ", is now known to be intimately connected to the immune system through different cell types and cytokines. While type 2 immune responses have traditionally been associated with allergy and parasitic infections, emerging evidence suggests that these responses also play a crucial role in CNS homeostasis and disease pathogenesis. Type...
Source: Cellular and Molecular Immunology - July 10, 2023 Category: Molecular Biology Authors: Tornike Mamuladze Jonathan Kipnis Source Type: research

The Relationship of Parasite Allergens to Allergic Diseases
AbstractPurpose of ReviewHelminth infections modify the natural history of allergic diseases, by either decreasing or increasing their symptoms. Several helminth components are involved in the increasing of the allergic response and symptoms, overcoming the concomitant immunosuppression of helminthiases. However, the role of individual IgE-binding molecules in this process remains to be defined.Recent FindingsWe updated the list of helminth allergens and IgE-binding molecules, their effects on asthma presentation, and their impact on allergy diagnosis. Data from genetic and epigenetic studies of ascariasis are analyzed. A ...
Source: Current Allergy and Asthma Reports - July 1, 2023 Category: Allergy & Immunology Source Type: research

Feline heartworm disease and environmental allergens hypersensitivity: is there a link?
Cats can be infected by Dirofilaria immitis, the causative agent of heartworm disease, characterized by respiratory signs, airway hyperreactivity, remodelling and inflammation. Allergy is a multifactorial patholo...
Source: Parasites and Vectors - June 9, 2023 Category: Microbiology Authors: Sara N. Garc ía-Rodríguez, Noelia Costa-Rodríguez, Jorge I. Matos, Yaiza Falcón-Cordón, Rodrigo Morchón, Elena Carretón and José A. Montoya-Alonso Tags: Research Source Type: research

The Relationship of Parasite Allergens to Allergic Diseases
AbstractPurpose of ReviewHelminth infections modify the natural history of allergic diseases, by either decreasing or increasing their symptoms. Several helminth components are involved in the increasing of the allergic response and symptoms, overcoming the concomitant immunosuppression of helminthiases. However, the role of individual IgE-binding molecules in this process remains to be defined.Recent FindingsWe updated the list of helminth allergens and IgE-binding molecules, their effects on asthma presentation, and their impact on allergy diagnosis. Data from genetic and epigenetic studies of ascariasis are analyzed. A ...
Source: Current Allergy and Asthma Reports - June 3, 2023 Category: Allergy & Immunology Source Type: research

Basic mechanisms of itch
Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis, are selective C or A δ epidermal nerve endings which are pruriceptors. At their other ends, peripheral neurons form synapses with spinal neurons and interneurons. Many areas in the central nervous system are involved in itch processing. Although itch does not occur solely because of parasitic, allergic, or immunologica l diseases, it is usually the consequence of neuro-immune interactions. Histamine is involved in a minority of itchy conditions, and many other mediators play a role: cytokines (e.g., IL-4, IL-13, IL-31, IL-33, a...
Source: Journal of Allergy and Clinical Immunology - May 16, 2023 Category: Allergy & Immunology Authors: Laurent Misery, Oph élie Pierre, Christelle Le Gall-Ianotto, Nicolas Lebonvallet, Pavel V. Chernyshov, Raphaële Le Garrec, Matthieu Talagas Source Type: research

Eosinophilic inflammation of the digestive tract
Ann Pathol. 2023 May 10:S0242-6498(23)00091-3. doi: 10.1016/j.annpat.2023.04.007. Online ahead of print.ABSTRACTEosinophilic inflammation of the digestive tract is an inflammatory disease characterized by extensive infiltration of eosinophils into the gastrointestinal tract. It can be either a primary disorder of the digestive tract or be secondary to another cause of tissue eosinophilia. Primary disorders include eosinophilic esophagitis (OE) and eosinophilic gastroenteritis (GEEo). These are 2 rare pathologies considered to be diseases related to a Th2-mediated food allergy. The role of the pathologist is twofold: (1) he...
Source: Annales de Pathologie - May 12, 2023 Category: Pathology Authors: Nathalie Guedj Dominique Cazals-Hatem Source Type: research