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Infectious Disease: Parasitic Diseases

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Total 613 results found since Jan 2013.

The effect of infectious agents on the prevalence of allergies
CONCLUSIONS: A history of some forms of either infectious or parasitic diseases has a measurable effect on the risk of developing allergies.PMID:34597894 | DOI:10.1016/j.advms.2021.08.002
Source: Advances in Medical Sciences - October 1, 2021 Category: Biomedical Science Authors: Edyta Krzych-Fa łta Oksana Wojas Filip Raciborski Aneta Tomaszewska Piotr Samel-Kowalik Konrad Furma ńczyk Edward Si ński Ma łgorzata Bednarska Daniel Rabczenko Boles ław Samoliński Source Type: research

Cancers, Vol. 13, Pages 4460: Insights from IgE Immune Surveillance in Allergy and Cancer for Anti-Tumour IgE Treatments
oweth Silvia Crescioli IgE, the predominant antibody class of the allergic response, is known for its roles in protecting against parasites; however, a growing body of evidence indicates a significant role for IgE and its associated effector cells in tumour immunosurveillance, highlighted by the field of AllergoOncology and the successes of the first-in-class IgE cancer therapeutic MOv18. Supporting this concept, substantial epidemiological data ascribe potential roles for IgE, allergy, and atopy in protecting against specific tumour types, with a corresponding increased cancer risk associated with IgE immunodeficien...
Source: Cancers - September 4, 2021 Category: Cancer & Oncology Authors: Alex J. McCraw Jitesh Chauhan Heather J. Bax Chara Stavraka Gabriel Osborn Melanie Grandits Jacobo L ópez-Abente Debra H. Josephs James Spicer Gerd K. Wagner Sophia N. Karagiannis Alicia Chenoweth Silvia Crescioli Tags: Review Source Type: research

Prostaglandin regulation of type 2 inflammation: from basic biology to therapeutic interventions
This article is protected by copyright. All rights reserved.PMID:34396535 | DOI:10.1002/eji.202048909
Source: European Journal of Immunology - August 16, 2021 Category: Allergy & Immunology Authors: Oyebola O Oyesola Elia D Tait Wojno Source Type: research

STAT5 Represses a STAT3-Independent Th17-like Program during Th9 Cell Differentiation
In this study, we demonstrate that human allergy-associated Th9 cells exhibited a signature of STAT5-mediated gene repression that is associated with the silencing of a Th17-like transcriptional signature. In murine Th9 cell differentiation, blockade of IL-2/STAT5 signaling induced the expression of IL-17 and the Th17-associated transcription factor Rorγt. However, IL-2-deprived Th9 cells did not exhibit a significant Th17- or STAT3-associated transcriptional signature. Consistent with these observations, differentiation of IL-17-producing cells under these conditions was STAT3-independent but did require Rorγt and BATF....
Source: Journal of Immunology - August 5, 2021 Category: Allergy & Immunology Authors: D Alejandro Canaria Bingyu Yan Maia G Clare Zonghao Zhang Grace A Taylor David L Boone Majid Kazemian Matthew R Olson Source Type: research