Effectiveness of antazoline versus amiodarone, flecainide and propafenone in restoring sinus rhythm at the Emergency Department
CONCLUSIONS: This is the first study comparing the effectiveness of antazoline in PCV versus flecainide in addition to the previously studied amiodarone and propafenone. Our results indicate that antazoline is more effective in restoring SR than amiodarone, flecainide and propafenone. In addition, antazoline restored SR significantly faster than amiodarone or propafenone.PMID:38649031 | DOI:10.1016/j.advms.2024.04.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 22, 2024 Category: Biomedical Science Authors: Janusz Springer Michalina Pejska Wojciech Homenda Tomasz Zdrojewski Ludmi ła Daniłowicz-Szymanowicz Dariusz Koz łowski Source Type: research

The SPRI determination of cathepsin L and S in plasma and peritoneal fluid of women with endometriosis
CONCLUSIONS: Based on the results of this study, it appears that cathepsins L and S are not suitable candidates as biomarkers for endometriosis.PMID:38642611 | DOI:10.1016/j.advms.2024.04.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 20, 2024 Category: Biomedical Science Authors: Julia Za łęcka Zuzanna Zieli ńska Łukasz Ołdak Agata Sakowicz Grzegorz Ma ńka Mariusz Kiecka Robert Spaczy ński Piotr Piekarski Beata Banaszewska Artur Jakimiuk Tadeusz Issat Jakub M łodawski Maria Szubert Piotr Sieroszewski Grzegorz Raba Kamil Sz Source Type: research

Single-cell sequencing analysis confirms the association of ANRIL with the increased smooth muscle cell proliferation and migration gene signatures in pulmonary artery hypertension in silico
CONCLUSION: SMCs exhibited significant heterogeneity in PAH. The altered abilities of SMC proliferation and migration in PAH were associated with ANRIL expression.PMID:38631609 | DOI:10.1016/j.advms.2024.04.002 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 17, 2024 Category: Biomedical Science Authors: Yan Li Yan-Tong Zhang Bing Han Lan Xue Yan Wei Ge Li Source Type: research

Single-cell sequencing analysis confirms the association of ANRIL with the increased smooth muscle cell proliferation and migration gene signatures in pulmonary artery hypertension in silico
CONCLUSION: SMCs exhibited significant heterogeneity in PAH. The altered abilities of SMC proliferation and migration in PAH were associated with ANRIL expression.PMID:38631609 | DOI:10.1016/j.advms.2024.04.002 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 17, 2024 Category: Biomedical Science Authors: Yan Li Yan-Tong Zhang Bing Han Lan Xue Yan Wei Ge Li Source Type: research

Obesity - Standards, trends and advances
Adv Med Sci. 2024 Apr 9;69(1):208-215. doi: 10.1016/j.advms.2024.04.001. Online ahead of print.ABSTRACTObesity continues to be a significant global health concern, giving rise to various complications. This review article explores the current standards and emerging innovations in diagnosing and treating obesity, including recent disease name change, staging system or therapeutic goals. This narrative review has been based on recent scientific articles from PubMed database, limiting the scope of topics to current standards and upcoming developments and breakthroughs in the diagnosis and treatment of obesity. The educational...
Source: Advances in Medical Sciences - April 11, 2024 Category: Biomedical Science Authors: Jakub Go łacki Beata Matyjaszek-Matuszek Source Type: research

Obesity - Standards, trends and advances
Adv Med Sci. 2024 Apr 9;69(1):208-215. doi: 10.1016/j.advms.2024.04.001. Online ahead of print.ABSTRACTObesity continues to be a significant global health concern, giving rise to various complications. This review article explores the current standards and emerging innovations in diagnosing and treating obesity, including recent disease name change, staging system or therapeutic goals. This narrative review has been based on recent scientific articles from PubMed database, limiting the scope of topics to current standards and upcoming developments and breakthroughs in the diagnosis and treatment of obesity. The educational...
Source: Advances in Medical Sciences - April 11, 2024 Category: Biomedical Science Authors: Jakub Go łacki Beata Matyjaszek-Matuszek Source Type: research

Obesity - Standards, trends and advances
Adv Med Sci. 2024 Apr 9:S1896-1126(24)00022-1. doi: 10.1016/j.advms.2024.04.001. Online ahead of print.ABSTRACTObesity continues to be a significant global health concern, giving rise to various complications. This review article explores the current standards and emerging innovations in diagnosing and treating obesity, including recent disease name change, staging system or therapeutic goals. This narrative review has been based on recent scientific articles from PubMed database, limiting the scope of topics to current standards and upcoming developments and breakthroughs in the diagnosis and treatment of obesity. The edu...
Source: Advances in Medical Sciences - April 11, 2024 Category: Biomedical Science Authors: Jakub Go łacki Beata Matyjaszek-Matuszek Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghadah Nazar Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research

Impact of NMDA receptors block versus GABA-A receptors modulation on synaptic plasticity and brain electrical activity in metabolic syndrome
CONCLUSIONS: Both Allo and Memantine boosted the outcome parameters in the animal model of MetS. Allo markedly improved the anxiety-like behavior in the form of significantly decreased grooming frequency compared to the Memantine-treated groups. Both drugs were associated with increased hippocampal GFAP and BDNF expression, indicating an improvement in synaptic plasticity and so, cognition-related behaviors.PMID:38561071 | DOI:10.1016/j.advms.2024.03.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 1, 2024 Category: Biomedical Science Authors: Shaimaa Nasr Amin Sherif Ahmed Shaltout Walaa Bayoumie El Gazzar Noha Samir Abdel Latif Ghada Al-Jussani Yasmeen Jamal Alabdallat Khaled Anwer Albakri Dalia Azmy Elberry Source Type: research