Efficacy of high-dose corticosteroid-based treatment for chronic lymphocytic leukemia patients with p53 abnormalities in the era of B-cell receptor inhibitors
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Bartosz Puła, Monika Długosz-Danecka, Aleksander Salomon-Perzyński, Agnieszka Szymczyk, Edyta Subocz, Bożena Katarzyna Budziszewska, Justyna Rybka, Lidia Gil, Anna Waszczuk-Gajda, Elżbieta Iskierka-Jażdżewska, Jan M. Zaucha, Michał Osowiecki, Weronika Piszczek, Paweł Steckiewicz, Łukasz Szukalski, Marek Hus, Ewa Lech-Marańda, Wojciech Jurczak, Krzysztof Jamroziak (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - July 12, 2020 Category: Biomedical Science Source Type: research

Lung ultrasound in the diagnosis of COVID-19 infection - A case series and review of the literature
Publication date: Available online 25 June 2020Source: Advances in Medical SciencesAuthor(s): Natalia Buda, Elena Segura-Grau, Jolanta Cylwik, Marcin Wełnicki (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 27, 2020 Category: Biomedical Science Source Type: research

Iron, ferroptosis, and new insights for prevention in acute kidney injury
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Bartlomiej Borawski, Jolanta Malyszko (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 25, 2020 Category: Biomedical Science Source Type: research

Quantitative changes in selected bacteria in the stool during the treatment of Crohn's disease
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Dominika Salamon, Tomasz Gosiewski, Agnieszka Krawczyk, Agnieszka Sroka-Oleksiak, Mariusz Duplaga, Krzysztof Fyderek, Kinga Kowalska-Duplaga (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 24, 2020 Category: Biomedical Science Source Type: research

Gene expression analysis of activating and inhibitory receptors of natural killer cells in patients with acute myeloblastic leukemia
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Narges Ghasemimehr, Vahid Moazed, Ahmad Fatemi (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 24, 2020 Category: Biomedical Science Source Type: research

Anti-fibrotic effect of iguratimod on pulmonary fibrosis by inhibiting the fibroblast–to-myofibroblast transition
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Haobo Lin, Chaochen Wu, Fu Zhu, Guangfeng Zhang, Yuesheng Xie, Yang Cui, Guangfu Dong, Xiao Zhang (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 24, 2020 Category: Biomedical Science Source Type: research

Gene expression analysis of activating and inhibitory receptors of natural killer cells in patients with acute myeloblastic leukemia.
CONCLUSION: Herewith, we show a statistical difference in mRNA expression levels of activating (NKp46) and inhibitory receptors from NK cells in newly diagnosed AML patients when compared with healthy controls or patients who received induction therapy, supporting the findings of researchers who reported the impaired NK cells cytotoxicity in AML patients. PMID: 32592956 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 24, 2020 Category: Biomedical Science Authors: Ghasemimehr N, Moazed V, Fatemi A Tags: Adv Med Sci Source Type: research

Iron, ferroptosis, and new insights for prevention in acute kidney injury.
Abstract Acute kidney injury (AKI) is a very common condition with high morbidity and mortality, which can be seen in 5-7% of all hospitalized patients and in up to 57% of all intensive care unit admissions. Despite recent advances in clinical care, the prevalence of AKI has been shown to increase with virtually no change in mortality. AKI is a complex syndrome occurring in a variety of clinical settings. Early detection is crucial to prevent irreversible loss of renal function. The pathogenesis of AKI is highly multifactorial and complex, including vasoconstriction, reactive oxygen species formation, cell death, ...
Source: Advances in Medical Sciences - June 24, 2020 Category: Biomedical Science Authors: Borawski B, Malyszko J Tags: Adv Med Sci Source Type: research

Anti-fibrotic effect of iguratimod on pulmonary fibrosis by inhibiting the fibroblast-to-myofibroblast transition.
CONCLUSIONS: Our results collectively revealed the beneficial effect of IGU on the inhibition of FMT, thus suggesting that it might act as an effective anti-fibrotic agent in preventing the progression of PF. PMID: 32590154 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 23, 2020 Category: Biomedical Science Authors: Lin H, Wu C, Zhu F, Zhang G, Xie Y, Cui Y, Dong G, Zhang X Tags: Adv Med Sci Source Type: research

Quantitative changes in selected bacteria in the stool during the treatment of Crohn's disease.
CONCLUSION: The implemented treatment (EEN or IFX) modifies the microbiome in CD patients, but does not make it become the same as in HC. PMID: 32590155 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 23, 2020 Category: Biomedical Science Authors: Salamon D, Gosiewski T, Krawczyk A, Sroka-Oleksiak A, Duplaga M, Fyderek K, Kowalska-Duplaga K Tags: Adv Med Sci Source Type: research

Comparison of the offspring ultrasound thyroid volume in hypothyroid mothers treated with different levothyroxine doses: A cohort study
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Aleksandra Mikołajczak, Maria Katarzyna Borszewska-Kornacka, Ewa Romejko-Wolniewicz, Renata Bokiniec (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 22, 2020 Category: Biomedical Science Source Type: research

Comparison of the offspring ultrasound thyroid volume in hypothyroid mothers treated with different levothyroxine doses: A cohort study.
CONCLUSION: Results of the present study indicate that maternal thyroid hormone levels may interfere with the fetal hypothalamic-pituitary axis. PMID: 32580143 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 21, 2020 Category: Biomedical Science Authors: Mikołajczak A, Borszewska-Kornacka MK, Romejko-Wolniewicz E, Bokiniec R Tags: Adv Med Sci Source Type: research

Effect of ytterbium amount on LaNbO4:Tm3+,Yb3+ nanoparticles for bio-labelling applications
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Nathalia da Silva Marques, Eduardo José Nassar, Marc Verelst, Robert Mauricot, Helena Brunckova, Lucas Alonso Rocha (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 18, 2020 Category: Biomedical Science Source Type: research

Effect of ytterbium amount on LaNbO4:Tm3+,Yb3+ nanoparticles for bio-labelling applications.
CONCLUSIONS: The intensity of positive conversion emissions depends directly on Yb3+ concentration. The bio-labelling tests pointed to the potential application of these materials. The sample containing the highest amount of Yb3+ provided better results and was easier to detect than the standard sample. PMID: 32563181 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 17, 2020 Category: Biomedical Science Authors: da Silva Marques N, Nassar EJ, Verelst M, Mauricot R, Brunckova H, Rocha LA Tags: Adv Med Sci Source Type: research

Efficacy of ipilimumab after anti-PD-1 therapy in sequential treatment of metastatic melanoma patients - Real world evidence
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Bożena Cybulska-Stopa, Paweł Rogala, Anna M. Czarnecka, Iwona Ługowska, Paweł Teterycz, Łukasz Galus, Marcin Rajczykowski, Anna Dawidowska, Karolina Piejko, Rafał Suwiński, Jacek Mackiewicz, Piotr Rutkowski (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 16, 2020 Category: Biomedical Science Source Type: research

Efficacy of ipilimumab after anti-PD-1 therapy in sequential treatment of metastatic melanoma patients - Real world evidence.
CONCLUSIONS: Ipilimumab could be considered after anti-PD-1 treatment. Treatment with ipilimumab following anti-PD-1 therapy showed beneficial effects in patients with normal levels of LDH, 2 or less number of metastatic locations, and BRAF-mutated melanoma. However, further studies are required to confirm our results as the study included a low number of patients with BRAF mutation-positive melanoma. No significant increase in toxicity was detected with the use of ipilimumab after anti-PD-1 therapy. PMID: 32554313 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 15, 2020 Category: Biomedical Science Authors: Cybulska-Stopa B, Rogala P, Czarnecka AM, Ługowska I, Teterycz P, Galus Ł, Rajczykowski M, Dawidowska A, Piejko K, Suwiński R, Mackiewicz J, Rutkowski P Tags: Adv Med Sci Source Type: research

Characteristics of platelet indices and their prognostic significance in selected medical condition – a systematic review
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Karolina Pogorzelska, Anna Krętowska, Maryna Krawczuk-Rybak, Małgorzata Sawicka-Żukowska (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 4, 2020 Category: Biomedical Science Source Type: research

Characteristics of platelet indices and their prognostic significance in selected medical condition - a systematic review.
CONCLUSIONS: Platelet indices may have prognostic and predictive value in numerous conditions. PMID: 32505856 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - June 4, 2020 Category: Biomedical Science Authors: Pogorzelska K, Krętowska A, Krawczuk-Rybak M, Sawicka-Żukowska M Tags: Adv Med Sci Source Type: research

Sensitization to major Dermatophagoides pteronyssinus allergens in house dust mite allergic patients from North Eastern Poland developing rhinitis or asthma
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Krzysztof Kowal, Agnieszka Pampuch, Grzegorz Siergiejko, Zenon Siergiejko, Ewa Swiebocka, Caleb R. Schlachter, Maksymilian Chruszcz, Alain Jacquet (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 29, 2020 Category: Biomedical Science Source Type: research

Sensitization to major Dermatophagoides pteronyssinus allergens in house dust mite allergic patients from North Eastern Poland developing rhinitis or asthma.
CONCLUSIONS: HDM-APs from North-Eastern Poland display sensitization profile to major allergens which is similarly observed in western Europe. HDM-based diagnostic and therapeutic products should include all major allergens. PMID: 32474401 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 28, 2020 Category: Biomedical Science Authors: Kowal K, Pampuch A, Siergiejko G, Siergiejko Z, Swiebocka E, Schlachter CR, Chruszcz M, Jacquet A Tags: Adv Med Sci Source Type: research

Pulmonary vascular resistance as a potential marker of reactive pulmonary hypertension reduction following sildenafil therapy in patients disqualified from orthotopic heart transplantation
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Agata Duszańska, Jaroslaw Wasilewski, Marek Gierlotka, Michal Zakliczyński (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 24, 2020 Category: Biomedical Science Source Type: research

Editorial Board
Publication date: March 2020Source: Advances in Medical Sciences, Volume 65, Issue 1Author(s): (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 23, 2020 Category: Biomedical Science Source Type: research

Pulmonary vascular resistance as a potential marker of reactive pulmonary hypertension reduction following sildenafil therapy in patients disqualified from orthotopic heart transplantation.
Abstract PURPOSE: We sought to determine the predictors of restoration of heart transplantation (HTx) candidacy in patients with systolic heart failure (HF) and reactive fixed pulmonary hypertension (RFPH) defined as pulmonary vascular resistance (PVR) > 2.5 Wood units (WU), transpulmonary gradient (TPG) > 12 mmHg or ≤2.5 WU with systolic arterial pressure ≤85 mmHg during vasoreactivity test, following sildenafil therapy. MATERIAL AND METHODS: Between 2007 and 2018 1136 patients were evaluated at our department as candidates for HTx. Thirty-five of them, who presented...
Source: Advances in Medical Sciences - May 23, 2020 Category: Biomedical Science Authors: Duszańska A, Wasilewski J, Gierlotka M, Zakliczyński M Tags: Adv Med Sci Source Type: research

Analysis of the tumor necrosis factor superfamily member 11 gene polymorphism with bone mineral density and bone fracture frequency in patients with postmenopausal osteoporosis
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Anna Wawrzyniak, Marzena Skrzypczak-Zielinska, Iwona Krela-Kazmierczak, Michal Michalak, Daria Marszalek, Michalina Marcinkowska, Oliwia Zakerska-Banaszak, Ryszard Slomski (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 20, 2020 Category: Biomedical Science Source Type: research

Analysis of the tumor necrosis factor superfamily member 11 gene polymorphism with bone mineral density and bone fracture frequency in patients with postmenopausal osteoporosis.
CONCLUSIONS: Variant rs9533156 may contribute to the genetic regulation of BMD in Polish postmenopausal osteoporosis, while the exon 5 sequence of the TNFSF11 gene is very conservative. PMID: 32446200 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - May 20, 2020 Category: Biomedical Science Authors: Wawrzyniak A, Skrzypczak-Zielinska M, Krela-Kazmierczak I, Michalak M, Marszalek D, Marcinkowska M, Zakerska-Banaszak O, Slomski R Tags: Adv Med Sci Source Type: research

Brain tissue oxygenation during transnasal endoscopic skull base procedures
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Tomasz Lyson, Andrzej Sieskiewicz, Robert Rutkowski, Magdalena Rybaczek, Andrzej Sobolewski, Krzysztof Gorbacz, Jacek Krajewski, Jan Kochanowicz, Marek Rogowski, Zenon Mariak (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 30, 2020 Category: Biomedical Science Source Type: research

Brain tissue oxygenation during transnasal endoscopic skull base procedures.
Abstract PURPOSE: We aimed to study brain tissue oxygenation during the period of controlled reduction of arterial blood pressure - a maneuver often used in extended endoscopic skull base surgery for bloodless operative field. METHODS: Intracranial pressure, arterial blood pressure and the resultant cerebral perfusion pressure were measured during extended endoscopic skull base surgery in 5 patients with diagnosed tumors of the skull base and arterial hypertension. Simultaneously, in those patients, we measured partial pressure of oxygen in the brain parenchyma (PbtO2). RESULTS: Values of PbtO2 lower tha...
Source: Advances in Medical Sciences - April 30, 2020 Category: Biomedical Science Authors: Lyson T, Sieskiewicz A, Rutkowski R, Rybaczek M, Sobolewski A, Gorbacz K, Krajewski J, Kochanowicz J, Rogowski M, Mariak Z Tags: Adv Med Sci Source Type: research

Neurotoxicity of antineoplastic drugs: Mechanisms, susceptibility, and neuroprotective strategies
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Claudia Pellacani, Georgios Eleftheriou (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 29, 2020 Category: Biomedical Science Source Type: research

Correlation between biomarkers (calprotectin, seromucoid, metalloproteinase-3 and CRP) and clinical and endoscopic activity of ulcerative colitis in children
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Barbara Iwańczak, Małgorzata Ruczka, Małgorzata Matusiewicz, Tomasz Pytrus, Krzysztof Matusiewicz, Elżbieta Krzesiek (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 29, 2020 Category: Biomedical Science Source Type: research

Correlation between biomarkers (calprotectin, seromucoid, metalloproteinase-3 and CRP) and clinical and endoscopic activity of ulcerative colitis in children.
CONCLUSIONS: The examined inflammatory markers such as FC, as well as serum seromucoid and MMP-3 levels may be helpful in the assessment of large intestine mucosal healing. PMID: 32361483 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 28, 2020 Category: Biomedical Science Authors: Iwańczak B, Ruczka M, Matusiewicz M, Pytrus T, Matusiewicz K, Krzesiek E Tags: Adv Med Sci Source Type: research

Neurotoxicity of antineoplastic drugs: Mechanisms, susceptibility, and neuroprotective strategies.
Abstract This review summarizes the adverse effects on the central and/or peripheral nervous systems that may occur in response to antineoplastic drugs. In particular, we describe the neurotoxic side effects of the most commonly used drugs, such as platinum compounds, doxorubicin, ifosfamide, 5-fluorouracil, vinca alkaloids, taxanes, methotrexate, bortezomib and thalidomide. Neurotoxicity may result from direct action of compounds on the nervous system or from metabolic alterations produced indirectly by these drugs, and either the central nervous system or the peripheral nervous system, or both, may be affected. ...
Source: Advances in Medical Sciences - April 28, 2020 Category: Biomedical Science Authors: Pellacani C, Eleftheriou G Tags: Adv Med Sci Source Type: research

miR-141-3p promotes proliferation and metastasis of nasopharyngeal carcinoma by targeting NME1
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Manyi Li, Haiping Huang, Fuwei Cheng, Xiaoqing Hu, Jisheng Liu (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 14, 2020 Category: Biomedical Science Source Type: research

miR-141-3p promotes proliferation and metastasis of nasopharyngeal carcinoma by targeting NME1.
CONCLUSIONS: We confirmed that miR-141-3p promotes the proliferation and metastasis of NPC by targeting NME1. PMID: 32299022 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 13, 2020 Category: Biomedical Science Authors: Li M, Huang H, Cheng F, Hu X, Liu J Tags: Adv Med Sci Source Type: research

The beneficial role of FeNO in association with GINA guidelines for titration of inhaled corticosteroids in adult asthma: A randomized study
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Tung Truong-Thanh, Anh Vo-Thi-Kim, Thuc Vu-Minh, Dung Truong-Viet, Huong Tran-Van, Sy Duong-Quy (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 8, 2020 Category: Biomedical Science Source Type: research

The beneficial role of FeNO in association with GINA guidelines for titration of inhaled corticosteroids in adult asthma: A randomized study.
CONCLUSION: The use of FeNO in association with GINA guidelines has a beneficial role for accurate daily dose of ICS in adult patients with asthma. PMID: 32276003 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 7, 2020 Category: Biomedical Science Authors: Truong-Thanh T, Vo-Thi-Kim A, Vu-Minh T, Truong-Viet D, Tran-Van H, Duong-Quy S Tags: Adv Med Sci Source Type: research

Clarithromycin effectively enhances doxorubicin-induced cytotoxicity and apoptosis in MCF7 cells through dysregulation of autophagy
Publication date: September 2020Source: Advances in Medical Sciences, Volume 65, Issue 2Author(s): Nahid Amani, Mohammad Shokrzadeh, Fatemeh Shaki (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 4, 2020 Category: Biomedical Science Source Type: research

Clarithromycin effectively enhances doxorubicin-induced cytotoxicity and apoptosis in MCF7 cells through dysregulation of autophagy.
CONCLUSIONS: These findings suggest that suppression of autophagy by CAM may promote chemotherapeutic outcome in breast cancer. However, further investigations are needed to evaluate the application of CAM in adjuvant breast cancer therapy. PMID: 32252007 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - April 3, 2020 Category: Biomedical Science Authors: Amani N, Shokrzadeh M, Shaki F Tags: Adv Med Sci Source Type: research

He said, she said: Sex differences in peripheral artery disease
Publication date: March 2020Source: Advances in Medical Sciences, Volume 65, Issue 1Author(s): Shahbaz A. Malik, Andrew M. Goldsweig (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - March 13, 2020 Category: Biomedical Science Source Type: research

He said, she said: Sex differences in peripheral artery disease.
PMID: 32172155 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - March 12, 2020 Category: Biomedical Science Authors: Malik SA, Goldsweig AM Tags: Adv Med Sci Source Type: research

Auditory evoked potentials might have the potential to serve as early indicators related to amyloid beta peptide toxicity
Publication date: March 2020Source: Advances in Medical Sciences, Volume 65, Issue 1Author(s): Enis Hidisoglu, Piraye Yargicoglu (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 29, 2020 Category: Biomedical Science Source Type: research

Auditory evoked potentials might have the potential to serve as early indicators related to amyloid beta peptide toxicity.
CONCLUSIONS: AEPs might be used as a biomarker to determine the Aβ1-42 related neuronal degeneration in the auditory networks. PMID: 32120237 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 28, 2020 Category: Biomedical Science Authors: Hidisoglu E, Yargicoglu P Tags: Adv Med Sci Source Type: research

Role of Apelin/APJ axis in cancer development and progression
Publication date: March 2020Source: Advances in Medical Sciences, Volume 65, Issue 1Author(s): Javad Masoumi, Abdollah Jafarzadeh, Hossein Khorramdelazad, Morteza Abbasloui, Jalal Abdolalizadeh, Najmeh JamaliAbstractApelin is an endogenous peptide, which is expressed in a vast board of organs such as the brain, placenta, heart, lungs, kidneys, pancreas, testis, prostate and adipose tissues. The apelin receptor, called angiotensin-like-receptor 1 (APJ), is also expressed in the brain, spleen, placenta, heart, liver, intestine, prostate, thymus, testis, ovary, lungs, kidneys, stomach, and adipose tissue. The apelin/APJ axis ...
Source: Advances in Medical Sciences - February 20, 2020 Category: Biomedical Science Source Type: research

Value of magnetic resonance enterography in diagnosis and treatment follow up in Crohn’s disease in children
ConclusionsMRE is an efficient diagnostic tool in proper characterization of disease location in pediatric CD. As positive correlation of the results of MRE with the endoscopic and clinical activity has been found, taking into account good tolerance and non-invasiveness of the procedure it can be recommended to be used in reassessment. (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 20, 2020 Category: Biomedical Science Source Type: research

Role of Apelin/APJ axis in cancer development and progression.
Abstract Apelin is an endogenous peptide, which is expressed in a vast board of organs such as the brain, placenta, heart, lungs, kidneys, pancreas, testis, prostate and adipose tissues. The apelin receptor, called angiotensin-like-receptor 1 (APJ), is also expressed in the brain, spleen, placenta, heart, liver, intestine, prostate, thymus, testis, ovary, lungs, kidneys, stomach, and adipose tissue. The apelin/APJ axis is involved in a number of physiological and pathological processes. The apelin expression is increased in various kinds of cancer and the apelin/APJ axis plays a key role in the development of tumo...
Source: Advances in Medical Sciences - February 19, 2020 Category: Biomedical Science Authors: Masoumi J, Jafarzadeh A, Khorramdelazad H, Abbasloui M, Abdolalizadeh J, Jamali N Tags: Adv Med Sci Source Type: research

Value of magnetic resonance enterography in diagnosis and treatment follow up in Crohn's disease in children.
CONCLUSIONS: MRE is an efficient diagnostic tool in proper characterization of disease location in pediatric CD. As positive correlation of the results of MRE with the endoscopic and clinical activity has been found, taking into account good tolerance and non-invasiveness of the procedure it can be recommended to be used in reassessment. PMID: 32087571 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 19, 2020 Category: Biomedical Science Authors: Krzesiek E, Nienartowicz E, Iwańczak B Tags: Adv Med Sci Source Type: research

Gender differences and long-term clinical outcomes in patients with chronic total occlusions of infrainguinal lower limb arteries treated from retrograde access with peripheral vascular interventions
ConclusionMales are at increased risk of re-PVI compared to females with PAD and CTOs of infrainguinal arteries treated with PVI from retrograde access. (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 1, 2020 Category: Biomedical Science Source Type: research

Gender differences and long-term clinical outcomes in patients with chronic total occlusions of infrainguinal lower limb arteries treated from retrograde access with peripheral vascular interventions.
CONCLUSION: Males are at increased risk of re-PVI compared to females with PAD and CTOs of infrainguinal arteries treated with PVI from retrograde access. PMID: 32014808 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - January 31, 2020 Category: Biomedical Science Authors: Pawlik A, Januszek R, Ruzsa Z, Óriás V, Kleczyński P, Wojtasik-Bakalarz J, Arif S, Nyerges A, Chyrchel M, Stanek A, Dudek D, Bartuś S Tags: Adv Med Sci Source Type: research

Sexual disorders and dyspnoea among women with obstructive sleep apnea
ConclusionsOSA probably does not influence the prevalence of sexual dysfunction in females. However, OSA, as well as the higher level of dyspnea assessed by NYHA, may decrease sexual body image and sexual performance in females. (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - January 29, 2020 Category: Biomedical Science Source Type: research

Sexual disorders and dyspnoea among women with obstructive sleep apnea.
CONCLUSIONS: OSA probably does not influence the prevalence of sexual dysfunction in females. However, OSA, as well as the higher level of dyspnea assessed by NYHA, may decrease sexual body image and sexual performance in females. PMID: 32000113 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - January 27, 2020 Category: Biomedical Science Authors: Skoczyński S, Nowosielski K, Minarowski Ł, Brożek G, Oraczewska A, Glinka K, Ficek K, Kotulska B, Tobiczyk E, Skomro R, Mróz R, Barczyk A Tags: Adv Med Sci Source Type: research

Geographic disparities in the application of endovascular repair of unruptured abdominal aortic aneurysm - Polish population analysis
ConclusionsStriking differences in the relative numbers of unruptured AAA repairs and in the population characteristics in various districts of the country point to the possibility of different health needs in the regions and variations in standards of care. (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - January 23, 2020 Category: Biomedical Science Source Type: research