Potential of the postoperative lymphocyte-to-monocyte and monocyte-to-red blood cell ratio in predicting locoregional and distant metastases after breast cancer resection - Retrospective study
CONCLUSION: Our results revealed that both postoperative LMR and MRR are independent predictors of DFS in breast cancer patients. Large-scale prospective investigations are needed to validate our findings.PMID:38394965 | DOI:10.1016/j.advms.2024.02.006 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 23, 2024 Category: Biomedical Science Authors: Joanna Grupi ńska Magdalena Budzy ń Jakub Janowski Jacek Brzezi ński Bogna Gryszczy ńska Ewa Leporowska Dorota Formanowicz Witold Kycler Source Type: research
Metformin improves d-galactose induced premature ovarian insufficiency through PI3K-Akt-FOXO3a pathway
CONCLUSION: This study demonstrates that MET partially rescued ovarian dysfunction and apoptosis induced by d-galactose via a mechanism involving PI3K-Akt-FOXO3a pathway. Our finding proposed that MET may be a promising alternative treatment for POI.PMID:38387407 | DOI:10.1016/j.advms.2024.02.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Fatima Ellibishy Maha Tarek Marwa M Abd-Elsalam Nesreen Elgayar Wesam El Bakly Source Type: research
Can non-invasive cardiac hemodynamics and fluid content system (NICaS) parameters predict Acute Heart Failure outcomes in Caucasian and Asian patients in the emergency department?
CONCLUSIONS: The results indicate that NICaS technology offers a simple, non-invasive, and reliable method of assessing cardiac hemodynamics and congestion in AHF patients. These measurements may enhance diagnosis, tailor management plans, stratify risk, and predict outcomes in both Caucasian and Asian patients.PMID:38387408 | DOI:10.1016/j.advms.2024.02.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Muhammad Anshory Win Sen Kuan M Saifur Rohman Yoga Waranugraha Putri Annisa Kamila Agustin Iskandar Hani Susianti Ying Wei Yau Crystal Harn Wei Soh Khalid Mohammed Ali Mui Teng Chua Salvatore Di Somma Source Type: research
Critical roles of PAI-1 in lipopolysaccharide-induced acute lung injury
CONCLUSIONS: PAI-1 KO could aggravate ALI induced by LPS at 48 h. PAI-1 may be an important target to improve the prognosis of ALI.PMID:38387409 | DOI:10.1016/j.advms.2024.01.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Miao Li Juan Song Xinjun Tang Jing Bi Yufan Li Cuicui Chen Nana Feng Yuanlin Song Linlin Wang Source Type: research
Metformin improves d-galactose induced premature ovarian insufficiency through PI3K-Akt-FOXO3a pathway
CONCLUSION: This study demonstrates that MET partially rescued ovarian dysfunction and apoptosis induced by d-galactose via a mechanism involving PI3K-Akt-FOXO3a pathway. Our finding proposed that MET may be a promising alternative treatment for POI.PMID:38387407 | DOI:10.1016/j.advms.2024.02.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Fatima Ellibishy Maha Tarek Marwa M Abd-Elsalam Nesreen Elgayar Wesam El Bakly Source Type: research
Can non-invasive cardiac hemodynamics and fluid content system (NICaS) parameters predict Acute Heart Failure outcomes in Caucasian and Asian patients in the emergency department?
CONCLUSIONS: The results indicate that NICaS technology offers a simple, non-invasive, and reliable method of assessing cardiac hemodynamics and congestion in AHF patients. These measurements may enhance diagnosis, tailor management plans, stratify risk, and predict outcomes in both Caucasian and Asian patients.PMID:38387408 | DOI:10.1016/j.advms.2024.02.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Muhammad Anshory Win Sen Kuan M Saifur Rohman Yoga Waranugraha Putri Annisa Kamila Agustin Iskandar Hani Susianti Ying Wei Yau Crystal Harn Wei Soh Khalid Mohammed Ali Mui Teng Chua Salvatore Di Somma Source Type: research
Critical roles of PAI-1 in lipopolysaccharide-induced acute lung injury
CONCLUSIONS: PAI-1 KO could aggravate ALI induced by LPS at 48 h. PAI-1 may be an important target to improve the prognosis of ALI.PMID:38387409 | DOI:10.1016/j.advms.2024.01.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 22, 2024 Category: Biomedical Science Authors: Miao Li Juan Song Xinjun Tang Jing Bi Yufan Li Cuicui Chen Nana Feng Yuanlin Song Linlin Wang Source Type: research
The association between growth differentiation factor 15 and presence and severity of coronary atherosclerosis
CONCLUSION: GDF-15 is an independent predictor of CAD and is associated with CAD severity in terms of SYNTAX, SYNTAX II PCI and SYNTAX II CABG scores.PMID:38368744 | DOI:10.1016/j.advms.2024.02.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Emrah Ozdemir Berna Stavileci Bahar Ozdemir Faik Alper Aksoy Serkan Kahraman Ceyla Zeynep Colakoglu Gevher Murat Ziyrek Ali Dogan Source Type: research
Transcriptome profiling as a biological marker for bipolar disorder sub-phenotypes
CONCLUSIONS: The most specific transcriptome profile was revealed in BP with psychotic symptoms. Differentially expressed genes in this variant include, among others, genes involved in inflammatory and immune processes. It might suggest the overlap of biological background between BP with a history of psychotic features and schizophrenia.PMID:38368745 | DOI:10.1016/j.advms.2024.02.002 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Joanna Pawlak Aleksandra Szczepankiewicz Maria Skibi ńska Beata Naro żna Pawe ł Kapelski Przemys ław Zakowicz Karolina Gattner Dominik Spa łek Łukasz Mech Monika Dmitrzak-W ęglarz Source Type: research
The association between growth differentiation factor 15 and presence and severity of coronary atherosclerosis
CONCLUSION: GDF-15 is an independent predictor of CAD and is associated with CAD severity in terms of SYNTAX, SYNTAX II PCI and SYNTAX II CABG scores.PMID:38368744 | DOI:10.1016/j.advms.2024.02.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Emrah Ozdemir Berna Stavileci Bahar Ozdemir Faik Alper Aksoy Serkan Kahraman Ceyla Zeynep Colakoglu Gevher Murat Ziyrek Ali Dogan Source Type: research
Transcriptome profiling as a biological marker for bipolar disorder sub-phenotypes
CONCLUSIONS: The most specific transcriptome profile was revealed in BP with psychotic symptoms. Differentially expressed genes in this variant include, among others, genes involved in inflammatory and immune processes. It might suggest the overlap of biological background between BP with a history of psychotic features and schizophrenia.PMID:38368745 | DOI:10.1016/j.advms.2024.02.002 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Joanna Pawlak Aleksandra Szczepankiewicz Maria Skibi ńska Beata Naro żna Pawe ł Kapelski Przemys ław Zakowicz Karolina Gattner Dominik Spa łek Łukasz Mech Monika Dmitrzak-W ęglarz Source Type: research
The association between growth differentiation factor 15 and presence and severity of coronary atherosclerosis
CONCLUSION: GDF-15 is an independent predictor of CAD and is associated with CAD severity in terms of SYNTAX, SYNTAX II PCI and SYNTAX II CABG scores.PMID:38368744 | DOI:10.1016/j.advms.2024.02.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Emrah Ozdemir Berna Stavileci Bahar Ozdemir Faik Alper Aksoy Serkan Kahraman Ceyla Zeynep Colakoglu Gevher Murat Ziyrek Ali Dogan Source Type: research
Transcriptome profiling as a biological marker for bipolar disorder sub-phenotypes
CONCLUSIONS: The most specific transcriptome profile was revealed in BP with psychotic symptoms. Differentially expressed genes in this variant include, among others, genes involved in inflammatory and immune processes. It might suggest the overlap of biological background between BP with a history of psychotic features and schizophrenia.PMID:38368745 | DOI:10.1016/j.advms.2024.02.002 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 18, 2024 Category: Biomedical Science Authors: Joanna Pawlak Aleksandra Szczepankiewicz Maria Skibi ńska Beata Naro żna Pawe ł Kapelski Przemys ław Zakowicz Karolina Gattner Dominik Spa łek Łukasz Mech Monika Dmitrzak-W ęglarz Source Type: research
Changes in arterial pH do not explain the reductions in ionised calcium observed during COVID-19 infection
CONCLUSION: Reduction in iCa concentration in patients with COVID-19 is not associated with pH derangement. Influenza infection was associated with a minor reduction in iCa in our small sample, a hitherto unreported finding, although statistical significance was not demonstrated.PMID:38364757 | DOI:10.1016/j.advms.2024.02.001 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 16, 2024 Category: Biomedical Science Authors: John Scott Frazer Robin Lucas-Evans Asghar Dayala Dennis A Mlangeni Source Type: research
Changes in arterial pH do not explain the reductions in ionised calcium observed during COVID-19 infection
CONCLUSION: Reduction in iCa concentration in patients with COVID-19 is not associated with pH derangement. Influenza infection was associated with a minor reduction in iCa in our small sample, a hitherto unreported finding, although statistical significance was not demonstrated.PMID:38364757 | DOI:10.1016/j.advms.2024.02.001 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - February 16, 2024 Category: Biomedical Science Authors: John Scott Frazer Robin Lucas-Evans Asghar Dayala Dennis A Mlangeni Source Type: research
