Investigation of the effects of urotensin II receptors in LPS-induced inflammatory response in HUVEC cell line through calcineurin/NFATc/IL-2 pathway
CONCLUSION: U-II and its receptors can perform key functions regarding the endothelial cell damage via the CaN/NFATc/IL-2 pathway.PMID:37913738 | DOI:10.1016/j.advms.2023.10.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 1, 2023 Category: Biomedical Science Authors: Zekai Halici Vedat Bulut Elif Cadirci Muhammed Yayla Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research

Ceramides and their roles in programmed cell death
This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research

Extracellular vesicle-derived circHIPK3: Novel diagnostic biomarker for lung cancer
CONCLUSIONS: Taken together, our study shows that EV-derived circHIPK3 can serve as a promising biomarker for LC patient diagnosis. However, the downstream mRNA of the circHIPK3/miR-637 axis requires further exploration to enrich our understanding of circHIPK3's mechanism in LC.PMID:37866205 | DOI:10.1016/j.advms.2023.10.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Yingying Zhu Li Shen Qiuyan Xia Heyun Tao Zhanguo Liu Mengdie Wang Xiaomin Zhang Jun Zhang Jian Lv Source Type: research