Ceramides and their roles in programmed cell death

This article provides an overview of the current understanding of ceramides and their impact on various types of programmed cell death, including apoptosis, anoikis, macroautophagy and mitophagy, and necroptosis. Moreover, it highlights the emergence of dihydroceramides as a new class of bioactive sphingolipids and their downstream targets as well as their future roles in cancer cell growth, drug resistance and tumor metastasis.PMID:37866204 | DOI:10.1016/j.advms.2023.10.004

Source: Advances in Medical Sciences - October 22, 2023 Category: Biomedical Science Authors: Martina Bago Pil átová Zuzana Sol árová Roman Mezencev Peter Sol ár Source Type: research