Coding RNA expression profile and transcription factor analysis of H.pylori-associated chronic atrophic gastritis
CONCLUSION: The expression of APOA1, CYP3A4, FOXP3, CCR7, and CCL19 are the potential indicators for CAG to GC development, being the biomarkers to predict progression of CAG and poor prognosis of GC.PMID:37945439 | DOI:10.1016/j.advms.2023.10.007 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 9, 2023 Category: Biomedical Science Authors: Xinguo Wang Juan Dong Hao Sheng Xingting Ma Lazati Baheti Jie Xu Source Type: research
The use of non-invasive respiratory assistance to facilitate bronchofiberoscopy performance in patients with hypoxemic (type one) respiratory failure - Study protocol
CONCLUSION: The expected findings of this study would allow for careful selection of respiratory support method to safely perform FOB in patients with hypoxemic RF.PMID:37945440 | DOI:10.1016/j.advms.2023.10.011 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 9, 2023 Category: Biomedical Science Authors: Aleksandra Oraczewska Szczepan Cofta Adam Warcholi ński Ewa Trejnowska Grzegorz Bro żek Andrzej Swinarew Daiana Stolz Raffaele Scala Adam Barczyk Szymon Skoczy ński Source Type: research
May noninvasive mechanical ventilation and/ or continuous positive airway pressure increase the bronchoalveolar lavage salvage in patients with pulmonary diseases? Randomized clinical trial - Study protocol
CONCLUSION: The results of our prospective study will address the currently unsolved problem of how to increase BAL salvage in patients with pulmonary diseases without increasing the risk of respiratory failure exacerbation.PMID:37945441 | DOI:10.1016/j.advms.2023.10.009 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 9, 2023 Category: Biomedical Science Authors: Anna Danel Ewelina Tobiczyk Adam Warcholi ński Marzena Trzaska-Sobczak Andrzej Swinarew Grzegorz Bro żek Ewa Trejnowska Halina Batura-Gabryel Antonina Jedynak Raffaele Scala Adam Barczyk Szczepan Cofta Szymon Skoczy ński Source Type: research
A comprehensive review of ACE2, ACE1, TMPRSS2 and IFITM3 gene polymorphisms and their effect on the severity of COVID-19
This study aimed to analyze DNA polymorphisms in the ACE2, ACE1, TMPRSS2, and IFITM3 genes. Findings showed certain polymorphisms appear to be associated with the severity of the disease, including respiratory, coronary, and neurological disorders. The results also indicated that certain polymorphisms were protective against this virus. Varying populations have a different frequency of high-risk polymorphisms, so different treatment and preventative techniques must be implemented. Additional population studies should be conducted in this region to reduce the incidence of COVID-19-related morbidity and mortality.PMID:379260...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Parisa Sahranavard-Pirbazari Azin Khoshghiafeh Mohammad Javad Kamali Hanieh Esfandiar Marzieh Bakhtiari Mohamadreza Ahmadifard Source Type: research
Heat shock proteins in cancer - Known but always being rediscovered: Their perspectives in cancer immunotherapy
Adv Med Sci. 2023 Nov 3;68(2):464-473. doi: 10.1016/j.advms.2023.10.005. Online ahead of print.ABSTRACTHeat shock proteins (HSPs) represent cellular chaperones that are classified into several families, including HSP27, HSP40, HSP60, HSP70, and HSP90. The role of HSPs in the cell includes the facilitation of protein folding and maintaining protein structure. Both processes play crucial roles during stress conditions in the cell such as heat shock, degradation, and hypoxia. Moreover, HSPs are important modulators of cellular proliferation and differentiation, and are strongly associated with the molecular orchestration of c...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Alena Mazurakova Zuzana Solarova Lenka Koklesova Martin Caprnda Robert Prosecky Artur Khakymov Denis Baranenko Peter Kubatka Ladislav Mirossay Peter Kruzliak Peter Solar Source Type: research
A comprehensive review of ACE2, ACE1, TMPRSS2 and IFITM3 gene polymorphisms and their effect on the severity of COVID-19
This study aimed to analyze DNA polymorphisms in the ACE2, ACE1, TMPRSS2, and IFITM3 genes. Findings showed certain polymorphisms appear to be associated with the severity of the disease, including respiratory, coronary, and neurological disorders. The results also indicated that certain polymorphisms were protective against this virus. Varying populations have a different frequency of high-risk polymorphisms, so different treatment and preventative techniques must be implemented. Additional population studies should be conducted in this region to reduce the incidence of COVID-19-related morbidity and mortality.PMID:379260...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Parisa Sahranavard-Pirbazari Azin Khoshghiafeh Mohammad Javad Kamali Hanieh Esfandiar Marzieh Bakhtiari Mohamadreza Ahmadifard Source Type: research
Heat shock proteins in cancer - Known but always being rediscovered: Their perspectives in cancer immunotherapy
Adv Med Sci. 2023 Nov 3;68(2):464-473. doi: 10.1016/j.advms.2023.10.005. Online ahead of print.ABSTRACTHeat shock proteins (HSPs) represent cellular chaperones that are classified into several families, including HSP27, HSP40, HSP60, HSP70, and HSP90. The role of HSPs in the cell includes the facilitation of protein folding and maintaining protein structure. Both processes play crucial roles during stress conditions in the cell such as heat shock, degradation, and hypoxia. Moreover, HSPs are important modulators of cellular proliferation and differentiation, and are strongly associated with the molecular orchestration of c...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Alena Mazurakova Zuzana Solarova Lenka Koklesova Martin Caprnda Robert Prosecky Artur Khakymov Denis Baranenko Peter Kubatka Ladislav Mirossay Peter Kruzliak Peter Solar Source Type: research
A comprehensive review of ACE2, ACE1, TMPRSS2 and IFITM3 gene polymorphisms and their effect on the severity of COVID-19
This study aimed to analyze DNA polymorphisms in the ACE2, ACE1, TMPRSS2, and IFITM3 genes. Findings showed certain polymorphisms appear to be associated with the severity of the disease, including respiratory, coronary, and neurological disorders. The results also indicated that certain polymorphisms were protective against this virus. Varying populations have a different frequency of high-risk polymorphisms, so different treatment and preventative techniques must be implemented. Additional population studies should be conducted in this region to reduce the incidence of COVID-19-related morbidity and mortality.PMID:379260...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Parisa Sahranavard-Pirbazari Azin Khoshghiafeh Mohammad Javad Kamali Hanieh Esfandiar Marzieh Bakhtiari Mohamadreza Ahmadifard Source Type: research
Heat shock proteins in cancer - Known but always being rediscovered: Their perspectives in cancer immunotherapy
Adv Med Sci. 2023 Nov 3;68(2):464-473. doi: 10.1016/j.advms.2023.10.005. Online ahead of print.ABSTRACTHeat shock proteins (HSPs) represent cellular chaperones that are classified into several families, including HSP27, HSP40, HSP60, HSP70, and HSP90. The role of HSPs in the cell includes the facilitation of protein folding and maintaining protein structure. Both processes play crucial roles during stress conditions in the cell such as heat shock, degradation, and hypoxia. Moreover, HSPs are important modulators of cellular proliferation and differentiation, and are strongly associated with the molecular orchestration of c...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Alena Mazurakova Zuzana Solarova Lenka Koklesova Martin Caprnda Robert Prosecky Artur Khakymov Denis Baranenko Peter Kubatka Ladislav Mirossay Peter Kruzliak Peter Solar Source Type: research
A comprehensive review of ACE2, ACE1, TMPRSS2 and IFITM3 gene polymorphisms and their effect on the severity of COVID-19
This study aimed to analyze DNA polymorphisms in the ACE2, ACE1, TMPRSS2, and IFITM3 genes. Findings showed certain polymorphisms appear to be associated with the severity of the disease, including respiratory, coronary, and neurological disorders. The results also indicated that certain polymorphisms were protective against this virus. Varying populations have a different frequency of high-risk polymorphisms, so different treatment and preventative techniques must be implemented. Additional population studies should be conducted in this region to reduce the incidence of COVID-19-related morbidity and mortality.PMID:379260...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Parisa Sahranavard-Pirbazari Azin Khoshghiafeh Mohammad Javad Kamali Hanieh Esfandiar Marzieh Bakhtiari Mohamadreza Ahmadifard Source Type: research
Heat shock proteins in cancer - Known but always being rediscovered: Their perspectives in cancer immunotherapy
Adv Med Sci. 2023 Nov 3;68(2):464-473. doi: 10.1016/j.advms.2023.10.005. Online ahead of print.ABSTRACTHeat shock proteins (HSPs) represent cellular chaperones that are classified into several families, including HSP27, HSP40, HSP60, HSP70, and HSP90. The role of HSPs in the cell includes the facilitation of protein folding and maintaining protein structure. Both processes play crucial roles during stress conditions in the cell such as heat shock, degradation, and hypoxia. Moreover, HSPs are important modulators of cellular proliferation and differentiation, and are strongly associated with the molecular orchestration of c...
Source: Advances in Medical Sciences - November 5, 2023 Category: Biomedical Science Authors: Alena Mazurakova Zuzana Solarova Lenka Koklesova Martin Caprnda Robert Prosecky Artur Khakymov Denis Baranenko Peter Kubatka Ladislav Mirossay Peter Kruzliak Peter Solar Source Type: research
Combination therapy along with mesenchymal stem cells in wound healing; the state of the art
Adv Med Sci. 2023 Nov 2;68(2):441-449. doi: 10.1016/j.advms.2023.10.006. Online ahead of print.ABSTRACTMesenchymal stem cells (MSCs) are being increasingly used in various therapeutic applications including skin tissue repair and wound healing. The positive effects of the MSCs therapy are largely elicited by immunomodulation, increasing angiogenesis, supporting extracellular matrix (ECM) and thus favoring skin structure. However, the therapeutic competences of MSC-based therapies are somewhat hindered by their apparent modest clinical merits, conferring the need for methods that would rise the efficacy of such therapies. A...
Source: Advances in Medical Sciences - November 4, 2023 Category: Biomedical Science Authors: Hossein Daneste Linda Mohammadzadeh Boukani Narges Ramezani Fatemeh Asadi Haider Kamil Zaidan Azita Sadeghzade Maedeh Ehsannia Ali Azarashk Nasim Gholizadeh Source Type: research
Combination therapy along with mesenchymal stem cells in wound healing; the state of the art
Adv Med Sci. 2023 Nov 2;68(2):441-449. doi: 10.1016/j.advms.2023.10.006. Online ahead of print.ABSTRACTMesenchymal stem cells (MSCs) are being increasingly used in various therapeutic applications including skin tissue repair and wound healing. The positive effects of the MSCs therapy are largely elicited by immunomodulation, increasing angiogenesis, supporting extracellular matrix (ECM) and thus favoring skin structure. However, the therapeutic competences of MSC-based therapies are somewhat hindered by their apparent modest clinical merits, conferring the need for methods that would rise the efficacy of such therapies. A...
Source: Advances in Medical Sciences - November 4, 2023 Category: Biomedical Science Authors: Hossein Daneste Linda Mohammadzadeh Boukani Narges Ramezani Fatemeh Asadi Haider Kamil Zaidan Azita Sadeghzade Maedeh Ehsannia Ali Azarashk Nasim Gholizadeh Source Type: research
Investigation of the effects of urotensin II receptors in LPS-induced inflammatory response in HUVEC cell line through calcineurin/NFATc/IL-2 pathway
CONCLUSION: U-II and its receptors can perform key functions regarding the endothelial cell damage via the CaN/NFATc/IL-2 pathway.PMID:37913738 | DOI:10.1016/j.advms.2023.10.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 1, 2023 Category: Biomedical Science Authors: Zekai Halici Vedat Bulut Elif Cadirci Muhammed Yayla Source Type: research
Investigation of the effects of urotensin II receptors in LPS-induced inflammatory response in HUVEC cell line through calcineurin/NFATc/IL-2 pathway
CONCLUSION: U-II and its receptors can perform key functions regarding the endothelial cell damage via the CaN/NFATc/IL-2 pathway.PMID:37913738 | DOI:10.1016/j.advms.2023.10.008 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - November 1, 2023 Category: Biomedical Science Authors: Zekai Halici Vedat Bulut Elif Cadirci Muhammed Yayla Source Type: research
