Genetic aberrations of homologous recombination repair pathways in prostate cancer: The prognostic and therapeutic implications
Adv Med Sci. 2023 Sep 25;68(2):359-365. doi: 10.1016/j.advms.2023.09.008. Online ahead of print.ABSTRACTProstate cancer (PC) is the second most common cancer in men worldwide. Homologous recombination repair (HRR) gene defects have been identified in a significant proportion of metastatic castration-resistant PC (mCRPC) and are associated with an increased risk of PC and more aggressive PC. Importantly, it has been well-documented that poly ADP-ribose polymerase (PARP) inhibition in cells with HR deficiency (HRD) can cause cell death. This has been exploited for the targeted treatment of PC patients with HRD by PARP inhibi...
Source: Advances in Medical Sciences - September 27, 2023 Category: Biomedical Science Authors: Hamidreza Saeidi Ikmal Hisyam Bakrin Chandramathi Samudi Raju Patimah Ismail Mohsen Saraf Mohd Ghani Khairul-Asri Source Type: research
Adjunctive use of platelet-rich fibrin in surgical treatment of furcation defects: A systematic review
Adv Med Sci. 2023 Sep 25;68(2):366-371. doi: 10.1016/j.advms.2023.09.009. Online ahead of print.ABSTRACTPeriodontitis is an infectious disease characterized by the inflammatory destruction of the tooth supporting tissues. In multi-rooted teeth, this process leads to periodontal destruction within furcations creating defects demanding in terms of treatment. Regeneration of class II furcation involvement, although possible, is considered an unpredictable procedure, especially in terms of the bone fill. The interest in wound healing improvement by additional use of autologous concentrates of growth factors remains high in man...
Source: Advances in Medical Sciences - September 27, 2023 Category: Biomedical Science Authors: Anna Skurska Marek Chwiedosik Zuzanna Ślebioda Source Type: research
Safety and efficacy of melatonin as an adjuvant therapy in COVID-19 patients: Systematic review and meta-analysis
CONCLUSION: Melatonin was found to have substantial effects on COVID-19 patients when used as adjuvant therapy, enhancing clinical improvement and decreasing time to recovery with a shorter length of hospital stay and a shorter duration of mechanical ventilation.PMID:37742478 | DOI:10.1016/j.advms.2023.09.007 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 24, 2023 Category: Biomedical Science Authors: Amira Mohamed Taha Sara Adel Abdelkader Saed Mostafa Hossam-Eldin Moawad Wesam Abd El-Tawab Moawad Tala Al-Hejazi Yosra Mousa Ramaswamy Sharma Russel J Reiter Source Type: research
Safety and efficacy of melatonin as an adjuvant therapy in COVID-19 patients: Systematic review and meta-analysis
CONCLUSION: Melatonin was found to have substantial effects on COVID-19 patients when used as adjuvant therapy, enhancing clinical improvement and decreasing time to recovery with a shorter length of hospital stay and a shorter duration of mechanical ventilation.PMID:37742478 | DOI:10.1016/j.advms.2023.09.007 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 24, 2023 Category: Biomedical Science Authors: Amira Mohamed Taha Sara Adel Abdelkader Saed Mostafa Hossam-Eldin Moawad Wesam Abd El-Tawab Moawad Tala Al-Hejazi Yosra Mousa Ramaswamy Sharma Russel J Reiter Source Type: research
Safety and efficacy of melatonin as an adjuvant therapy in COVID-19 patients: Systematic review and meta-analysis
CONCLUSION: Melatonin was found to have substantial effects on COVID-19 patients when used as adjuvant therapy, enhancing clinical improvement and decreasing time to recovery with a shorter length of hospital stay and a shorter duration of mechanical ventilation.PMID:37742478 | DOI:10.1016/j.advms.2023.09.007 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 24, 2023 Category: Biomedical Science Authors: Amira Mohamed Taha Sara Adel Abdelkader Saed Mostafa Hossam-Eldin Moawad Wesam Abd El-Tawab Moawad Tala Al-Hejazi Yosra Mousa Ramaswamy Sharma Russel J Reiter Source Type: research
Alternative donor strategy in unrelated hematopoietic stem cell transplantation - outcome with mismatched donors
CONCLUSION: Obtained results undisputedly indicate the necessity to further investigate this matter on a larger patient group, with focus on specific HLA alleles to define precisely priority criteria for selecting the best donor for all patients, thus improving the outcome of HSCT with an MMUD.PMID:37741003 | DOI:10.1016/j.advms.2023.09.003 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 23, 2023 Category: Biomedical Science Authors: Zorana Grubic Marija Maskalan Marija Burek Kamenaric Lana Desnica Mirta Mikulic Katarina Stingl Jankovic Nadira Durakovic Ranka Serventi Seiwerth Radovan Vrhovac Renata Zunec Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF- Β1/HMGB1 signaling pathway
CONCLUSIONS: The severity of fibrosis decreased with ramelteon application. These effects of ramelteon may be associated with NLRP3 inflammation cascade.PMID:37716182 | DOI:10.1016/j.advms.2023.09.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Pelin Aydin Zeynep B Aksakalli-Magden Maide S Civelek Sevgi Karabulut-Uzuncakmak Behzad Mokhtare Mustafa Ozkaraca Fatih Alper Zekai Halici Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF- Β1/HMGB1 signaling pathway
CONCLUSIONS: The severity of fibrosis decreased with ramelteon application. These effects of ramelteon may be associated with NLRP3 inflammation cascade.PMID:37716182 | DOI:10.1016/j.advms.2023.09.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Pelin Aydin Zeynep B Aksakalli-Magden Maide S Civelek Sevgi Karabulut-Uzuncakmak Behzad Mokhtare Mustafa Ozkaraca Fatih Alper Zekai Halici Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF- Β1/HMGB1 signaling pathway
CONCLUSIONS: The severity of fibrosis decreased with ramelteon application. These effects of ramelteon may be associated with NLRP3 inflammation cascade.PMID:37716182 | DOI:10.1016/j.advms.2023.09.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Pelin Aydin Zeynep B Aksakalli-Magden Maide S Civelek Sevgi Karabulut-Uzuncakmak Behzad Mokhtare Mustafa Ozkaraca Fatih Alper Zekai Halici Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
The melatonin agonist ramelteon attenuates bleomycin-induced lung fibrosis by suppressing the NLRP3/TGF- Β1/HMGB1 signaling pathway
CONCLUSIONS: The severity of fibrosis decreased with ramelteon application. These effects of ramelteon may be associated with NLRP3 inflammation cascade.PMID:37716182 | DOI:10.1016/j.advms.2023.09.004 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Pelin Aydin Zeynep B Aksakalli-Magden Maide S Civelek Sevgi Karabulut-Uzuncakmak Behzad Mokhtare Mustafa Ozkaraca Fatih Alper Zekai Halici Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005 (Source: Advances in Medical Sciences)
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
