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Infectious Disease: Parasitic Diseases

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Total 613 results found since Jan 2013.

Ascaris lumbricoides and ticks associated with sensitization to galactose α1,3-galactose and elicitation of the alpha-gal syndrome
IgE to galactose alpha-1,3 galactose (alpha-gal) causes alpha-gal syndrome (delayed anaphylaxis after ingestion of mammalian meat). Development of sensitization has been attributed to tick bites; however, the possible role of other parasites has not been well studied.
Source: Journal of Allergy and Clinical Immunology - July 28, 2021 Category: Allergy & Immunology Authors: Tatenda Murangi, Prema Prakash, Bernardo Pereira Moreira, Wisdom Basera, Maresa Botha, Stephen Cunningham, Heidi Facey-Thomas, Ali Halajian, Lokesh Joshi, Jordache Ramjith, Franco H. Falcone, William Horsnell, Michael E. Levin Source Type: research

Eosinophils in antiviral immunity and (perhaps) a benefit of having asthma during the SARS-CoV2 pandemic
Eosinophils are potent proinflammatory leukocytes defined by their expression of preformed cationic granules. Eosinophils have historically primarily been understood to have evolved to mediate toxic immune responses to parasites, while, more problematically, being toxic to airway epithelial cells and other healthy tissues.1 Recently, however, a role of eosinophils in eliminating viral pathogens has emerged, including studies reporting the contribution of eosinophils in the elimination of respiratory syncytial virus (RSV), influenza, parainfluenza and, rhinovirus.
Source: Annals of Allergy, Asthma and Immunology - July 1, 2021 Category: Allergy & Immunology Authors: Ryan Eid, Larry Borish Tags: Editorial Source Type: research

Investigational malaria vaccine gives strong, lasting protection
(NIH/National Institute of Allergy and Infectious Diseases) Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites. The vaccine combines live parasites with either of two widely used antimalarial drugs -- an approach termed chemoprophylaxis vaccination. A Phase 2 clinical trial of the vaccine is now underway in Mali, a malaria-endemic country.
Source: EurekAlert! - Infectious and Emerging Diseases - June 30, 2021 Category: Infectious Diseases Source Type: news

Bullous eosinophilic annular erythema
We present an unusual case of a 47-year-old patient who developed this condition.PMID:34118823 | DOI:10.5070/D327553623
Source: Dermatol Online J - June 13, 2021 Category: Dermatology Authors: Yun Pei Koh Hong Liang Tey Source Type: research