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Infectious Disease: Parasitic Diseases
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Total 613 results found since Jan 2013.
To thwart the next pandemic, ‘swientists’ hunt for flu viruses at U.S. hog shows
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Source: ScienceNOW - October 27, 2022 Category: Science Source Type: news
Identification of major human IgE-inducing parasite antigens: A path to therapeutic approaches?
Type 2 immunity is a hallmark of allergic diseases, in which it plays a detrimental role, and the major contributor to anti-helminth immunity.1,2 It is characterized by the production of an expanding subset of alarmins (IL-25, IL-33, and thymic stromal lymphopoietin) and cytokines (IL-4, IL5, IL-9, IL-13, IL-31, etc) and by the involvement of a specific group of cell subsets associated with innate and adaptive responses (group 2 innate lymphoid cells, dendritic cells, alternatively activated macrophages, mast cells, basophils, eosinophils, TH2 lymphocytes, and B lymphocytes), ultimately leading to IgE production by B cells.
Source: Journal of Allergy and Clinical Immunology - October 18, 2022 Category: Allergy & Immunology Authors: David Dombrowicz Tags: Editorial Source Type: research
Identification of major human IgE-inducing parasite antigens: a path to therapeutic approaches?
Source: Journal of Allergy and Clinical Immunology - October 18, 2022 Category: Allergy & Immunology Authors: David Dombrowicz Source Type: research
Policy Implications of the Southern and Central Africa International Center of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso-, and Holoendemic Transmission Zones in Zambia and Zimbabwe
Am J Trop Med Hyg. 2022 Oct 11;107(4_Suppl):68-74. doi: 10.4269/ajtmh.21-1288. Print 2022 Oct 11.ABSTRACTThe International Centers of Excellence for Malaria Research (ICEMR) were established by the National Institute of Allergy and Infectious Diseases more than a decade ago to provide multidisciplinary research support to malaria control programs worldwide, operating in endemic areas and contributing technology, expertise, and ultimately policy guidance for malaria control and elimination. The Southern and Central Africa ICEMR has conducted research across three main sites in Zambia and Zimbabwe that differ in ecology, ent...
Source: Am J Trop Med Hyg - October 13, 2022 Category: Infectious Diseases Authors: Amy Wesolowski Matthew M Ippolito Mary E Gebhardt Ellen Ferriss Jessica L Schue Tamaki Kobayashi Mike Chaponda Jean-Bertin Kabuya Mbanga Muleba Monicah Mburu Japhet Matoba Michael Musonda Ben Katowa Mukuma Lubinda Harry Hamapumbu Limonty Simubali Twig Mud Source Type: research
Allergy, Anaphylaxis, and Nonallergic Hypersensitivity: IgE, Mast Cells, and Beyond
IgE-mediated type I hypersensitivity reactions have many reported beneficial functions in immune defense against parasites, venoms, toxins, etc. However, they are best known for their role in allergies, currently affecting almost one third of the population worldwide. IgE-mediated allergic diseases result from a maladaptive type 2 immune response that promotes the synthesis of IgE antibodies directed at a special class of antigens called allergens. IgE antibodies bind to type I high-affinity IgE receptors (Fc εRI) on mast cells and basophils, sensitizing them to get triggered in a subsequent encounter with the cognate all...
Source: Medical Principles and Practice - October 11, 2022 Category: Internal Medicine Source Type: research
Allergy, Anaphylaxis and Non-Allergic Hypersensitivity: IgE, Mast Cells and Beyond
IgE-mediated type I hypersensitivity reactions have many reported beneficial functions in the immune defense against parasites, venoms, toxins etc. However, they are best-known for their role in allergy affecting nowadays almost one third of the population worldwide. IgE-mediated allergic diseases result from a maladaptive type 2 immune response that promotes the synthesis of IgE antibodies directed to a special class of antigens called allergens. IgE antibodies bind to type I high affinity IgE receptors (FcepsilonRI) on mast cells and basophils licensing them to get triggered in a subsequent encounter with the cognate all...
Source: Medical Principles and Practice - October 11, 2022 Category: Internal Medicine Source Type: research
Relationship between < b > < i > Blastocystis < /i > < /b > spp. with Accompanying Food Hypersensitivity and Chronic Spontaneous Urticaria
Conclusion: The eradication ofBlastocystis spp. can improve the disease activity in CSU and the presence of FHRs seems to be risky in CSU patients withBlastocystis spp.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - September 15, 2022 Category: Allergy & Immunology Source Type: research
Stem cell factor/mast cell/CCL2/monocyte/macrophage axis promotes Coxsackievirus B3 myocarditis and cardiac fibrosis by increasing Ly6C < sup > high < /sup > monocyte influx and fibrogenic mediators production
Immunology. 2022 Jul 31. doi: 10.1111/imm.13556. Online ahead of print.ABSTRACTMast cells (MCs), central players in allergy and parasitic infections, play key roles in inflammation and fibrosis. Here, the impact of MCs on the progression of Coxsackievirus B3 (CVB3)-induced viral myocarditis (VMC) and fibrosis was investigated using MC-deficient KitW-sh mice. Viral titres, cellular infiltrates and heart pathologies were evaluated and compared with wild-type (WT) mice during acute CVB3 infection of C57BL/6 mice. CVB3 infection induced an increased accumulation and degranulation of MCs in the hearts of mice during acute infec...
Source: Immunology - September 2, 2022 Category: Allergy & Immunology Authors: Yuan Luo Hongkai Zhang Jie Yu Lin Wei Min Li Wei Xu Source Type: research
