The IC87201 (a PSD95/nNOS Inhibitor) Attenuates Post- Stroke Injuries
Neurochem Res. 2024 Apr 24. doi: 10.1007/s11064-024-04140-w. Online ahead of print.ABSTRACTN-methyl-D-aspartate receptor-dependent excitotoxicity is one of the most important mechanisms underlying stroke injury and the resulting neuronal death. In the present study, in order to reduce post-stroke brain injury and improve behavioral performance, a new molecule named IC87201, which acts as an inhibitor of PSD95/nNOS interaction in the intracellular signaling pathway of NMDA receptors, was administered. Using the middle cerebral artery occlusion (MCAO) technique, 24 adult male rats were subjected to one hour of cerebral ische...
Source: Neurochemical Research - April 24, 2024 Category: Neuroscience Authors: Maryam Mohammadian Aminollah Bahaoddini Mohammad Reza Namavar Source Type: research

Preface for the Vicente Felipo Honorary Issue of Neurochemical Research
Neurochem Res. 2024 Apr 20. doi: 10.1007/s11064-024-04139-3. Online ahead of print.NO ABSTRACTPMID:38641758 | DOI:10.1007/s11064-024-04139-3 (Source: Neurochemical Research)
Source: Neurochemical Research - April 19, 2024 Category: Neuroscience Authors: Marta Llansola Source Type: research

Correction: Orientin Modulates Nrf2-ARE, PI3K/Akt, JNK-ERK1/2, and TLR4/NF-kB Pathways to Produce Neuroprotective Benefits in Parkinson's Disease
Neurochem Res. 2024 Apr 16. doi: 10.1007/s11064-024-04138-4. Online ahead of print.NO ABSTRACTPMID:38625635 | DOI:10.1007/s11064-024-04138-4 (Source: Neurochemical Research)
Source: Neurochemical Research - April 16, 2024 Category: Neuroscience Authors: Deepak Vasudevan Sajini Praveen Thaggikuppe Krishnamurthy Amritha Chakkittukandiyil Ravi Naik Mudavath Source Type: research

Correction: Orientin Modulates Nrf2-ARE, PI3K/Akt, JNK-ERK1/2, and TLR4/NF-kB Pathways to Produce Neuroprotective Benefits in Parkinson's Disease
Neurochem Res. 2024 Apr 16. doi: 10.1007/s11064-024-04138-4. Online ahead of print.NO ABSTRACTPMID:38625635 | DOI:10.1007/s11064-024-04138-4 (Source: Neurochemical Research)
Source: Neurochemical Research - April 16, 2024 Category: Neuroscience Authors: Deepak Vasudevan Sajini Praveen Thaggikuppe Krishnamurthy Amritha Chakkittukandiyil Ravi Naik Mudavath Source Type: research

Correction: Orientin Modulates Nrf2-ARE, PI3K/Akt, JNK-ERK1/2, and TLR4/NF-kB Pathways to Produce Neuroprotective Benefits in Parkinson's Disease
Neurochem Res. 2024 Apr 16. doi: 10.1007/s11064-024-04138-4. Online ahead of print.NO ABSTRACTPMID:38625635 | DOI:10.1007/s11064-024-04138-4 (Source: Neurochemical Research)
Source: Neurochemical Research - April 16, 2024 Category: Neuroscience Authors: Deepak Vasudevan Sajini Praveen Thaggikuppe Krishnamurthy Amritha Chakkittukandiyil Ravi Naik Mudavath Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research

Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis
Neurochem Res. 2024 Mar 30. doi: 10.1007/s11064-024-04131-x. Online ahead of print.ABSTRACTConvulsive status epilepticus (CSE) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. Multiple studies have demonstrated the critical roles that long non-coding RNA Mir155hg plays in a variety of diseases. However, less is known about the function and mechanism of Mir155hg in CSE. Here we investigate and elucidate the mechanism underlying the contribution of Mir155hg to CSE-induced hippocampal neuron injury. By applying high-throughput sequencing, we examine...
Source: Neurochemical Research - March 30, 2024 Category: Neuroscience Authors: Ming Wang Binyuan Xu Yangmei Xie Ge Yao Yinghui Chen Source Type: research