Working Memory in Patients with Varying Degree of Hepatic Encephalopathy (HE): A Pilot EEG-fNIRS Study
In conclusion, the presence of cirrhosis seemed to have more effects than CHE on working memory at baseline. A course of treatment with rifaximin was more beneficial to patients without CHE, who probably had more room for improvement in this complex task.PMID:37792136 | DOI:10.1007/s11064-023-04034-3 (Source: Neurochemical Research)
Source: Neurochemical Research - October 4, 2023 Category: Neuroscience Authors: Lisa Zarantonello Chiara Mangini Davide Erminelli Silvano Fasolato Paolo Angeli Piero Amodio Sara Montagnese Source Type: research
Density of Sphingosine-1-Phosphate Receptors Is Altered in Cortical Nerve-Terminals of Insulin-Resistant Goto-Kakizaki Rats and Diet-Induced Obese Mice
In this study, we determined the density of S1PRs in cortical synaptosomes from insulin-resistant Goto-Kakizaki (GK) rats and Wistar controls, and from mice fed a high-fat diet (HFD) and low-fat-fed controls. Relative to their controls, GK rats showed similar cortical S1P concentration despite higher S1P levels in plasma, yet lower density of S1PR1, S1PR2 and S1PR4 in nerve-terminal-enriched membranes. HFD-fed mice exhibited increased plasma and cortical concentrations of S1P, and decreased density of S1PR1 and S1PR4. These findings point towards altered S1P signaling in synapses of insulin resistance and diet-induced obes...
Source: Neurochemical Research - October 4, 2023 Category: Neuroscience Authors: Cecilia Skoug H üseyin Erdogan Lotte Vanherle Jo ão P P Vieira Frank Matthes Lena Eliasson Anja Meissner Jo ão M N Duarte Source Type: research
Anti-insomnia Effect of a Polyherbal Formulation on P-chlorophenyalanine Induced Experimental Animal Model
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04035-2. Online ahead of print.ABSTRACTSleep is a dynamic and controlled set of physiological and behavioural practices during which the stabilisation and restoration processes of the body take place properly. Therefore, sleep disorders, especially chronic insomnia, can harm an individual's physical and mental health. However, the therapeutic alternatives are limited and possess severe side effects. Thus, in this study, we aimed to investigate the anti-insomnia effect of a polyherbal formulation (Sleep) (SLP) on p-chlorophenyalanine (PCPA) induced insomnia in rats. Intrap...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: S Sheethal M Ratheesh Svenia P Jose S Sandya Sarala Samuel Jayashree Madhavan Source Type: research
A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04032-5. Online ahead of print.ABSTRACTNumerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally ingested, or applied topically, has commonly been employed as adjunctive therapy for individuals experiencing anxiety, insomnia, convulsions, pain, and cognitive impairment. The utilization of synthetic medications in the treatment of various disorders and symp...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: Mohammad Qneibi Sosana Bdir Celine Maayeh Mohammad Bdair Dana Sandouka Diana Basit Mira Hallak Source Type: research
Anti-insomnia Effect of a Polyherbal Formulation on P-chlorophenyalanine Induced Experimental Animal Model
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04035-2. Online ahead of print.ABSTRACTSleep is a dynamic and controlled set of physiological and behavioural practices during which the stabilisation and restoration processes of the body take place properly. Therefore, sleep disorders, especially chronic insomnia, can harm an individual's physical and mental health. However, the therapeutic alternatives are limited and possess severe side effects. Thus, in this study, we aimed to investigate the anti-insomnia effect of a polyherbal formulation (Sleep) (SLP) on p-chlorophenyalanine (PCPA) induced insomnia in rats. Intrap...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: S Sheethal M Ratheesh Svenia P Jose S Sandya Sarala Samuel Jayashree Madhavan Source Type: research
A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04032-5. Online ahead of print.ABSTRACTNumerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally ingested, or applied topically, has commonly been employed as adjunctive therapy for individuals experiencing anxiety, insomnia, convulsions, pain, and cognitive impairment. The utilization of synthetic medications in the treatment of various disorders and symp...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: Mohammad Qneibi Sosana Bdir Celine Maayeh Mohammad Bdair Dana Sandouka Diana Basit Mira Hallak Source Type: research
Anti-insomnia Effect of a Polyherbal Formulation on P-chlorophenyalanine Induced Experimental Animal Model
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04035-2. Online ahead of print.ABSTRACTSleep is a dynamic and controlled set of physiological and behavioural practices during which the stabilisation and restoration processes of the body take place properly. Therefore, sleep disorders, especially chronic insomnia, can harm an individual's physical and mental health. However, the therapeutic alternatives are limited and possess severe side effects. Thus, in this study, we aimed to investigate the anti-insomnia effect of a polyherbal formulation (Sleep) (SLP) on p-chlorophenyalanine (PCPA) induced insomnia in rats. Intrap...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: S Sheethal M Ratheesh Svenia P Jose S Sandya Sarala Samuel Jayashree Madhavan Source Type: research
A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04032-5. Online ahead of print.ABSTRACTNumerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally ingested, or applied topically, has commonly been employed as adjunctive therapy for individuals experiencing anxiety, insomnia, convulsions, pain, and cognitive impairment. The utilization of synthetic medications in the treatment of various disorders and symp...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: Mohammad Qneibi Sosana Bdir Celine Maayeh Mohammad Bdair Dana Sandouka Diana Basit Mira Hallak Source Type: research
Anti-insomnia Effect of a Polyherbal Formulation on P-chlorophenyalanine Induced Experimental Animal Model
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04035-2. Online ahead of print.ABSTRACTSleep is a dynamic and controlled set of physiological and behavioural practices during which the stabilisation and restoration processes of the body take place properly. Therefore, sleep disorders, especially chronic insomnia, can harm an individual's physical and mental health. However, the therapeutic alternatives are limited and possess severe side effects. Thus, in this study, we aimed to investigate the anti-insomnia effect of a polyherbal formulation (Sleep) (SLP) on p-chlorophenyalanine (PCPA) induced insomnia in rats. Intrap...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: S Sheethal M Ratheesh Svenia P Jose S Sandya Sarala Samuel Jayashree Madhavan Source Type: research
A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04032-5. Online ahead of print.ABSTRACTNumerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally ingested, or applied topically, has commonly been employed as adjunctive therapy for individuals experiencing anxiety, insomnia, convulsions, pain, and cognitive impairment. The utilization of synthetic medications in the treatment of various disorders and symp...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: Mohammad Qneibi Sosana Bdir Celine Maayeh Mohammad Bdair Dana Sandouka Diana Basit Mira Hallak Source Type: research
Anti-insomnia Effect of a Polyherbal Formulation on P-chlorophenyalanine Induced Experimental Animal Model
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04035-2. Online ahead of print.ABSTRACTSleep is a dynamic and controlled set of physiological and behavioural practices during which the stabilisation and restoration processes of the body take place properly. Therefore, sleep disorders, especially chronic insomnia, can harm an individual's physical and mental health. However, the therapeutic alternatives are limited and possess severe side effects. Thus, in this study, we aimed to investigate the anti-insomnia effect of a polyherbal formulation (Sleep) (SLP) on p-chlorophenyalanine (PCPA) induced insomnia in rats. Intrap...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: S Sheethal M Ratheesh Svenia P Jose S Sandya Sarala Samuel Jayashree Madhavan Source Type: research
A Comprehensive Review of Essential Oils and Their Pharmacological Activities in Neurological Disorders: Exploring Neuroprotective Potential
Neurochem Res. 2023 Sep 28. doi: 10.1007/s11064-023-04032-5. Online ahead of print.ABSTRACTNumerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally ingested, or applied topically, has commonly been employed as adjunctive therapy for individuals experiencing anxiety, insomnia, convulsions, pain, and cognitive impairment. The utilization of synthetic medications in the treatment of various disorders and symp...
Source: Neurochemical Research - September 28, 2023 Category: Neuroscience Authors: Mohammad Qneibi Sosana Bdir Celine Maayeh Mohammad Bdair Dana Sandouka Diana Basit Mira Hallak Source Type: research
RIP3 in Necroptosis: Underlying Contributions to Traumatic Brain Injury
In this report, we review different domains of RIP3, multiple analyses of necroptosis, and associations between necroptosis and TBI, RIP3, RIP1, and mixed lineage kinase domain-like. Next, we elucidate the potential involvement of RIP3 in TBI and highlight how RIP3 deficiency enhances neuronal function.PMID:37743445 | DOI:10.1007/s11064-023-04038-z (Source: Neurochemical Research)
Source: Neurochemical Research - September 24, 2023 Category: Neuroscience Authors: Lvxia Wang Yong Zhang Min Huang Yiling Yuan Xuehong Liu Source Type: research
RIP3 in Necroptosis: Underlying Contributions to Traumatic Brain Injury
In this report, we review different domains of RIP3, multiple analyses of necroptosis, and associations between necroptosis and TBI, RIP3, RIP1, and mixed lineage kinase domain-like. Next, we elucidate the potential involvement of RIP3 in TBI and highlight how RIP3 deficiency enhances neuronal function.PMID:37743445 | DOI:10.1007/s11064-023-04038-z (Source: Neurochemical Research)
Source: Neurochemical Research - September 24, 2023 Category: Neuroscience Authors: Lvxia Wang Yong Zhang Min Huang Yiling Yuan Xuehong Liu Source Type: research
RIP3 in Necroptosis: Underlying Contributions to Traumatic Brain Injury
In this report, we review different domains of RIP3, multiple analyses of necroptosis, and associations between necroptosis and TBI, RIP3, RIP1, and mixed lineage kinase domain-like. Next, we elucidate the potential involvement of RIP3 in TBI and highlight how RIP3 deficiency enhances neuronal function.PMID:37743445 | DOI:10.1007/s11064-023-04038-z (Source: Neurochemical Research)
Source: Neurochemical Research - September 24, 2023 Category: Neuroscience Authors: Lvxia Wang Yong Zhang Min Huang Yiling Yuan Xuehong Liu Source Type: research
