The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study
CONCLUSION: The respondents' risk of these supplements' use may partially reflect the public's behavioral response during a pandemic. Future studies can document the health beliefs and motivations of nutritional supplement users.PMID:36632904 | PMC:PMC9827747 | DOI:10.1016/j.ctim.2023.102917 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - January 12, 2023 Category: Complementary Medicine Authors: Nada Mohammed Hafiz Mahmoud Zaki El-Readi Ghada Esheba Mohammad Althubiti Nahla Ayoub Abdullah R Alzahrani Saeed S Al-Ghamdi Safaa Yehia Eid Source Type: research
The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study
CONCLUSION: The respondents' risk of these supplements' use may partially reflect the public's behavioral response during a pandemic. Future studies can document the health beliefs and motivations of nutritional supplement users.PMID:36632904 | PMC:PMC9827747 | DOI:10.1016/j.ctim.2023.102917 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - January 12, 2023 Category: Complementary Medicine Authors: Nada Mohammed Hafiz Mahmoud Zaki El-Readi Ghada Esheba Mohammad Althubiti Nahla Ayoub Abdullah R Alzahrani Saeed S Al-Ghamdi Safaa Yehia Eid Source Type: research
The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: a cross-sectional study
CONCLUSION: The respondents' risk of these supplements' use may partially reflect the public's behavioral response during a pandemic. Future studies can document the health beliefs and motivations of nutritional supplement users.PMID:36632904 | PMC:PMC9827747 | DOI:10.1016/j.ctim.2023.102917 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - January 12, 2023 Category: Complementary Medicine Authors: Nada Hassan Hafiz Mahmoud Zaki El-Readi Ghada Esheba Mohammad Althubiti Nahla Ayoub Abdullah R Alzahrani Saeed S Al-Ghamdi Safaa Yehia Eid Source Type: research
A small H < sub > 2 < /sub > O-soluble ingredient of royal jelly lower cholesterol levels in liver cells by suppressing squalene epoxidase
In this study, we investigated the efficacy of RJ on gene expression of squalene epoxidase (SE) a major enzyme involved in cholesterol biosynthesis in HepG2 cells. We found that the expression of SE was decreased in response to RJ treatment. We also found that the origin of the RJ affected its strength. To find out the active fraction of RJ in cholesterol suppression, we separated RJ into two parts based on the molecular weights using ultrafiltration membrane. We found that the fraction <10kDa from RJ had comparable effect on SE expression, especially its water-soluble part. Taken together, we think RJ suppresses choles...
Source: Atherosclerosis - December 30, 2022 Category: Cardiology Authors: Chi Wang Zhen-Yu Jiang Jing Wang Jia-Xin Lou Yuan-Yuan Nian Li-Xia Liu Tong Dang Xian-Mei Meng Source Type: research
A small H < sub > 2 < /sub > O-soluble ingredient of royal jelly lower cholesterol levels in liver cells by suppressing squalene epoxidase
In this study, we investigated the efficacy of RJ on gene expression of squalene epoxidase (SE) a major enzyme involved in cholesterol biosynthesis in HepG2 cells. We found that the expression of SE was decreased in response to RJ treatment. We also found that the origin of the RJ affected its strength. To find out the active fraction of RJ in cholesterol suppression, we separated RJ into two parts based on the molecular weights using ultrafiltration membrane. We found that the fraction <10kDa from RJ had comparable effect on SE expression, especially its water-soluble part. Taken together, we think RJ suppresses choles...
Source: Atherosclerosis - December 30, 2022 Category: Cardiology Authors: Chi Wang Zhen-Yu Jiang Jing Wang Jia-Xin Lou Yuan-Yuan Nian Li-Xia Liu Tong Dang Xian-Mei Meng Source Type: research
Major royal jelly proteins elicited suppression of SARS-CoV-2 entry and replication with halting lung injury
Int J Biol Macromol. 2022 Dec 28;228:715-731. doi: 10.1016/j.ijbiomac.2022.12.251. Online ahead of print.ABSTRACTFor reasons of high transmissibility and virulence, Alpha (UK, B.1.1.7) and Beta (South African, B.1.351) SARS-CoV-2 variants are classified with other types as variants of concern. Here we report on the influence of royal jelly (RJ) protein fraction (PF)50 (major RJ protein 2 and its isoform X1) on the entry of these variants into the ACE2-human embryonic kidney (HEK) 293 cells using the lentiviral system. The efficiency of PF50 on SARS-CoV-2 replication (RNA-dependent RNA polymerase "RdRp" activity), as well a...
Source: International Journal of Biological Macromolecules - December 30, 2022 Category: Biochemistry Authors: Marwa M Abu-Serie Noha H Habashy Source Type: research
Molecules, Vol. 28, Pages 227: Chemical Profiling and Nutritional Evaluation of Bee Pollen, Bee Bread, and Royal Jelly and Their Role in Functional Fermented Dairy Products
y A. El-Sohaimy
Honeybee products, as multicomponent substances, have been a focus of great interest. The present work aimed to perform the nutritional and chemical profiling and biochemical characterization of bee pollen (BP), bee bread (BB), and royal jelly (RJ) and study their applications in the fortification of functional fermented dairy products. Their effects on starter cultures and the physicochemical and sensorial quality of products were monitored. A molecular networking analysis identified a total of 46 compounds in the three bee products that could be potential medicines, including flavonoids, fatty acids, ...
Source: Molecules - December 27, 2022 Category: Chemistry Authors: Amira M. G. Darwish Aida A. Abd El-Wahed Mohamed G. Shehata Hesham R. El-Seedi Saad H. D. Masry Shaden A. M. Khalifa Hatem M. Mahfouz Sobhy A. El-Sohaimy Tags: Article Source Type: research
Protective Effect of Thyme and Chestnut Honeys Enriched with Bee Products against Benzo(a)pyrene-Induced DNA Damage
In conclusion, the thyme and chestnut honey samples enriched with bee products present potential as natural chemoprotective agents against the chemical carcinogen BaP.PMID:36554850 | DOI:10.3390/ijerph192416969 (Source: Cell Research)
Source: Cell Research - December 23, 2022 Category: Cytology Authors: Vanesa S ánchez-Martín Ana I Haza Amaia Iriondo-DeHond Mar ía Dolores Del Castillo Xavier F Hospital Manuela Fern ández Eva Hierro Paloma Morales Source Type: research
Investigation of the effects of the royal jelly on genomic demethylation and tumor suppressor genes in human cancer cells
AbstractRoyal jelly is a gelatinous nutrient secretion produced by the mandibular glands of young worker honey bees and has a critical role in honey bee life. In the honey bee colonies, queen and worker honey bees have very different morphologies and behaviors due to their diet in the larval period, despite having the same genome. In comparison, queen bees formed from larvae that feed royal jelly exclusively, and worker bees formed from larvae that feed on much less royal jelly. DNA methylation has been shown to play a critical role in the development of queen and worker honeybees. Alterations in DNA methylation, one of th...
Source: Medical Oncology - December 23, 2022 Category: Cancer & Oncology Source Type: research
IJERPH, Vol. 19, Pages 16969: Protective Effect of Thyme and Chestnut Honeys Enriched with Bee Products against Benzo(a)pyrene-Induced DNA Damage
In conclusion, the thyme and chestnut honey samples enriched with bee products present potential as natural chemoprotective agents against the chemical carcinogen BaP. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - December 17, 2022 Category: Environmental Health Authors: Vanesa S ánchez-Martín Ana I. Haza Amaia Iriondo-DeHond Mar ía Dolores del Castillo Xavier F. Hospital Manuela Fern ández Eva Hierro Paloma Morales Tags: Article Source Type: research
Royal jelly arranges apoptotic and oxidative stress pathways and reduces damage to liver tissues of rats by down-regulation of Bcl-2, GSK3 and NF- κB and up-regulation of Caspase and Nrf-2 protein signaling pathways
Biomarkers. 2022 Dec 15:1-14. doi: 10.1080/1354750X.2022.2159526. Online ahead of print.NO ABSTRACTPMID:36520139 | DOI:10.1080/1354750X.2022.2159526 (Source: Biomarkers)
Source: Biomarkers - December 15, 2022 Category: Research Authors: Abdullah Aslan Ozlem Gok Seda Beyaz Gozde Parlak Muhammed Ismail Can Ramazan Gundogdu Serpil Baspinar Ibrahim Hanifi Ozercan Akif Evren Parlak Source Type: research
