Agave fructanos promote in vitro biofilm formation with a probiotic consortium Lactobacillus delbrueckii ssp. lactis, L. delbrueckii ssp. bulgaricus and Streptococcus thermophilus
This study aimed to evaluate in vitro the biofilm formation in a consortium of lactic acid bacteria: Lactobacillus delbrueckii ssp. lactis, Lactobacillus delbrueckii ssp. bulgaricus y Streptococcus thermophilus in the presence of AF at different concentrations: 0%, 0,1%, 4%, 8% y 16%. The addition of 0,1% of AF correlates with the best capacity for biofilm formation. The findings imply the possibility of modulating the biofilm formation of lactic acid bacteria with AF. These results can contribute positively to the host, by generating intestinal homeostasis, colonization resistance, stability to food digestion and chemical...
Source: Revista Argentina de Microbiologia - April 4, 2024 Category: Microbiology Authors: Mary Carmen Citlally Condado Huerta Mayra Antunez-Mojica Haydee Mart ínez Plascencia Am érica Ivette Barrera Molina Source Type: research
Daily briefing: Gut bacteria can break down artery-clogging cholesterol
Nature, Published online: 04 April 2024; doi:10.1038/d41586-024-01026-3Oscillibacter species can transform cholesterol into a more harmless form — hinting at probiotic treatments. Plus, mRNA drug shows the technology’s potential beyond vaccines and how loneliness harms your health. (Source: Nature AOP)
Source: Nature AOP - April 4, 2024 Category: Research Authors: Flora Graham Source Type: research
Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment
In conclusion, the res ults of our study indicate that the utilization of AgNPs may represent a viable strategy for the eradication of liver cancerous cells through the activation of apoptosis and the enhancement of immune system reactions. (Source: Medical Oncology)
Source: Medical Oncology - April 4, 2024 Category: Cancer & Oncology Source Type: research
Impact of Limosilactobacillus fermentum probiotic treatment on gut microbiota composition in sahiwal calves with rotavirus diarrhea: A 16S metagenomic analysis study ”
Diarrhea poses a major threat to bovine calves leading to mortality and economic losses. Among the causes of calf diarrhea, bovine rotavirus is a major etiological agent and may result in dysbiosis of gut micr... (Source: BMC Microbiology)
Source: BMC Microbiology - April 4, 2024 Category: Microbiology Authors: Nadeem Murtaza, Muhammad Nawaz, Tahir Yaqub and Asim Khalid Mehmood Tags: Research Source Type: research
Our extended microbiome: The human-relevant metabolites and biology of fermented foods
Cell Metab. 2024 Apr 2;36(4):684-701. doi: 10.1016/j.cmet.2024.03.007.ABSTRACTOne of the key modes of microbial metabolism occurring in the gut microbiome is fermentation. This energy-yielding process transforms common macromolecules like polysaccharides and amino acids into a wide variety of chemicals, many of which are relevant to microbe-microbe and microbe-host interactions. Analogous transformations occur during the production of fermented foods, resulting in an abundance of bioactive metabolites. In foods, the products of fermentation can influence food safety and preservation, nutrient availability, and palatability...
Source: Cell Metabolism - April 3, 2024 Category: Cytology Authors: Elisa B Caffrey Justin L Sonnenburg Suzanne Devkota Source Type: research
Unlocking the power of postbiotics: A revolutionary approach to nutrition for humans and animals
Cell Metab. 2024 Apr 2;36(4):725-744. doi: 10.1016/j.cmet.2024.03.004.ABSTRACTPostbiotics, which comprise inanimate microorganisms or their constituents, have recently gained significant attention for their potential health benefits. Extensive research on postbiotics has uncovered many beneficial effects on hosts, including antioxidant activity, immunomodulatory effects, gut microbiota modulation, and enhancement of epithelial barrier function. Although these features resemble those of probiotics, the stability and safety of postbiotics make them an appealing alternative. In this review, we provide a comprehensive summary ...
Source: Cell Metabolism - April 3, 2024 Category: Cytology Authors: Xinjie Zhao Shuai Liu Sumin Li Wen Jiang Jingjun Wang Jianxin Xiao Tianyu Chen Jiaying Ma Muhammad Zahoor Khan Wei Wang Mengmeng Li Shengli Li Zhijun Cao Source Type: research
Adjunctive administration of parabiotic Lactobacillus sakei CVL-001 ameliorates drug-induced toxicity and pulmonary inflammation during antibiotic treatment for tuberculosis
Int Immunopharmacol. 2024 Apr 2;132:111937. doi: 10.1016/j.intimp.2024.111937. Online ahead of print.ABSTRACTTuberculosis (TB) treatment requires a long therapeutic duration and induces adverse effects such as hepatotoxicity, causing discontinuation of treatment. Reduced adherence to TB medications elevates the risk of recurrence and the development of drug resistance. Additionally, severe cavitary TB with a high burden of Mycobacterium tuberculosis (Mtb) and inflammation-mediated tissue damage may need an extended treatment duration, resulting in a higher tendency of drug-induced toxicity. We previously reported that the ...
Source: International Immunopharmacology - April 3, 2024 Category: Allergy & Immunology Authors: Hagyu Kim Eun-Jung Song Eunsol Choi Kee Woong Kwon Jong-Hwan Park Sung Jae Shin Source Type: research
Impact of Pediococcus acidilactici GLP06 supplementation on gut microbes and metabolites in adult beagles: a comparative analysis
In conclusion, this study presents evidence that supplementing with P. acidilactici GLP06 can have a positive impact on antioxidant activity, immunoproteins, SCFAs, and gut microbiota in adult beagles. These findings highlight the potential of probiotics as a dietary intervention to enhance gut health and overall wellbeing in companion animals. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - April 3, 2024 Category: Microbiology Source Type: research
The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications
This article summarises the most up-to-date knowledge in pharmacomicrobiomics in PD, and discusses how the manipulation of gut microbiota represents a potential new therapeutic avenue for PD. (Source: CNS Drugs)
Source: CNS Drugs - April 3, 2024 Category: Neurology Source Type: research
Probiotics —A Promising Novel Therapeutic Approach in the Management of Chronic Liver Diseases
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - April 3, 2024 Category: Nutrition Authors: Gokulapriya Ramachandran Biju Pottakkat Source Type: research
Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention
Paediatr Drugs. 2024 Apr 2. doi: 10.1007/s40272-024-00626-w. Online ahead of print.ABSTRACTNecrotizing enterocolitis (NEC) is a life-threatening disease predominantly affecting premature and very low birth weight infants resulting in inflammation and necrosis of the small bowel and colon and potentially leading to sepsis, peritonitis, perforation, and death. Numerous research efforts have been made to better understand, treat, and prevent NEC. This review explores a variety of factors involved in the pathogenesis of NEC (prematurity, low birth weight, lack of human breast milk exposure, alterations to the microbiota, mater...
Source: Paediatric Drugs - April 2, 2024 Category: Pediatrics Authors: Annette Gawron Roberts Noelle Younge Rachel Gottron Greenberg Source Type: research
Metabolic regulation of longevity and immune response in < em > Caenorhabditis elegans < /em > by ingestion of < em > Lacticaseibacillus rhamnosus < /em > IDCC 3201 using multi-omics analysis
In conclusion, this study demonstrated the probiotic properties of the candidate probiotic L. rhamnosus IDCC 3201 by using multi-omics analysis.PMID:38563104 | DOI:10.4014/jmb.2402.02025 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - April 2, 2024 Category: Biotechnology Authors: Daniel Junpyo Lee Ju Young Eor Min-Jin Kwak Junbeom Lee An Na Kang Daye Mun Hyejin Choi Minho Song Jong Nam Kim Jun-Mo Kim Jungwoo Yang Hyung Wook Kim Sangnam Oh Younghoon Kim Source Type: research
Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention
Paediatr Drugs. 2024 Apr 2. doi: 10.1007/s40272-024-00626-w. Online ahead of print.ABSTRACTNecrotizing enterocolitis (NEC) is a life-threatening disease predominantly affecting premature and very low birth weight infants resulting in inflammation and necrosis of the small bowel and colon and potentially leading to sepsis, peritonitis, perforation, and death. Numerous research efforts have been made to better understand, treat, and prevent NEC. This review explores a variety of factors involved in the pathogenesis of NEC (prematurity, low birth weight, lack of human breast milk exposure, alterations to the microbiota, mater...
Source: Paediatric Drugs - April 2, 2024 Category: Pediatrics Authors: Annette Gawron Roberts Noelle Younge Rachel Gottron Greenberg Source Type: research
