The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
The Beneficial Role of < em > Lactobacillus paracasei < /em > subsp. < em > paracasei < /em > NTU 101 in the Prevention of Atopic Dermatitis
In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) was orally administered for a duration of 4 weeks, followed by the induction of AD using ovalbumin (OVA) in a mouse model. The skin condition of the stimulated site was observed during the induction period. Subsequently, the serum immunoglobulin E (IgE) content, splenocyte T cell typing, and skin histological interpretation were examined to evaluate the efficacy of NTU 101 in alleviating AD symptoms in allergen-exposed animals. The findings indicated that administering NTU 101 beforehand effectively alleviated skin symptoms in animals with AD. It red...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Chin-Feng Liu Tsung-Wei Shih Chun-Lin Lee Tzu-Ming Pan Source Type: research
Probiotic lactic acid bacteria promote anti-tumor immunity through enhanced major histocompatibility complex class I-restricted antigen presentation machinery in dendritic cells
Lactic acid bacteria (LAB) possess the ability to argument T cell activity through functional modification of antigen presenting cells (APCs), such as dendritic cells (DCs) and macrophages. Nevertheless, the precise mechanism underlying LAB-induced enhancement of antigen presentation in APCs remains incompletely understood. To address this question, we investigated the detailed mechanism underlying the enhancement of major histocompatibility complex (MHC) class I-restricted antigen presentation in DCs using a probiotic strain known as Lactococcus lactis subsp. Cremoris C60. We found that Heat-killed-C60 (HK-C60) facilitate...
Source: Frontiers in Immunology - March 27, 2024 Category: Allergy & Immunology Source Type: research
Genomic insights from Lactiplantibacillus plantarum BRD3A isolated from Atingba, a traditional fermented rice-based beverage and analysis of its potential for probiotic and antimicrobial activity against Methicillin-resistant Staphylococcus aureus
Lactiplantibacillus plantarum BRD3A was isolated from Atingba, a traditional fermented rice-based beverage of Manipur. Its genomic sequence has 13 contigs and its genome size is 3,320,817 bp with a guanine–cytosine (GC) ratio of 44.6%. It comprises 3185 genes including 3112 coding sequences (CDSs), 73 RNAs (including 66 tRNAs and others), and one clustered regularly interspaced short palindromic repeat (CRISPR) array. A comparative and phylogenetic analysis with the Lp. plantarum genome shows that this strain has close similarity with other Lp. plantarum strains and about 99% average nucleotide identity. Functional annot...
Source: Frontiers in Microbiology - March 27, 2024 Category: Microbiology Source Type: research
Lacticaseibacillusparacasei BNCC345679 revolutionizes DSS-induced colitis and modulates gut microbiota
The gut microbiota plays an important role in the disease progression of inflammatory bowel disease. Although probiotics are effective against IBD, not many studies have investigated their effects on gut microbiota composition and immunomodulation in mouse colitis models. Our study aimed at the therapeutic effects of Lacticaseibacillus paracasei BNCC345679 for the first time and explored its impact on gut microbiome dysbiosis, inflammatory cytokines, related miRNAs, VCAM-1, oxidative stress, intestinal integrity, and mucus barrier. We found that oral intervention of L. paracasei BNCC345679 affects recovering beneficial mic...
Source: Frontiers in Microbiology - March 27, 2024 Category: Microbiology Source Type: research
