A concerted probiotic activity to inhibit periodontitis-associated bacteria
In conclusion, despite some natural limits such as persistence, the full potential for probiotic treatment is by far not utilized yet. Especially, further exploring concerted activity by combining synergistic strains, together with the application of oral prebiotics and essential supplements and conditions, is mandatory. (Source: PLoS One)
Source: PLoS One - March 5, 2021 Category: Biomedical Science Authors: Paul Mathias Jansen Source Type: research

Insight into probiotic properties of lactic acid bacterial endosymbionts of Apis mellifera L. derived from the Polish apiary
Publication date: March 2021Source: Saudi Journal of Biological Sciences, Volume 28, Issue 3Author(s): Artur Pachla, Aneta A. Ptaszyńska, Magdalena Wicha, Magdalena Kunat, Jerzy Wydrych, Ewa Oleńska, Wanda Małek (Source: Saudi Journal of Biological Sciences)
Source: Saudi Journal of Biological Sciences - March 4, 2021 Category: Biology Source Type: research

Pb Toxicity on Gut Physiology and Microbiota
Lead (Pb) is a toxic heavy metal, having profound threats to the global population. Multiple organs such as kidney, and liver, as well as nervous, hematologic, and reproductive systems, are commonly considered the targets of Pb toxicity. Increasing researches reported that the effects of Pb on gastrointestinal tracts are equally intensive, especially on intestinal microbiota. This review summarized Pb toxicity on gut physiology and microbiota in different animal models and in humans, of which the alterations may further have effects on other organs in host. To be more specific, Pb can impair gut barrier and increase gut pe...
Source: Frontiers in Physiology - March 4, 2021 Category: Physiology Source Type: research

Adaptation of Gut Microbiome to Transgenic Pigs Secreting β-Glucanase, Xylanase, and Phytase
In this study, we successfully generated EGFP marker-free transgenic (MF-TG) pigs with high expression levels of microbial β-glucanase, xylanase, and phytase in the parotid gland. We collected intestinal contents from the ileum, cecum and colon of five MF-TG and five wild-type (WT) sows and investigated the gut microbiome of the transgenic pigs via metagenomic analysis. Results showed that the levels of probiotics, such as Lactobacillus reuteri and Streptococcus, were more abundant in the cecum of the MF-TG pigs and higher than those of WT pigs. By contrast, the levels of harmful microorganisms, such as Campylobacter,...
Source: Frontiers in Genetics - March 4, 2021 Category: Genetics & Stem Cells Source Type: research

Development of a semi-dynamic in vitro model and its testing using probiotic Bacillus coagulans GBI-30, 6086 in orange juice and yogurt
Publication date: Available online 3 March 2021Source: Journal of Microbiological MethodsAuthor(s): Carine N. Almada-Érix, Caroline N. Almada, Geany T. Souza Pedrosa, Pablo C. Lollo, Marciane Magnani, Anderson S. Sant'Ana (Source: Journal of Microbiological Methods)
Source: Journal of Microbiological Methods - March 3, 2021 Category: Microbiology Source Type: research

The natural history of symptomatic uncomplicated diverticular disease: a long-term follow-up study
CONCLUSIONS: SUDD is an important disease able to affect patients significantly in the long term. Acute diverticulitis may sometimes occur in these patients, often leading to surgery with possible severe complications.PMID:33654361 | PMC:PMC7903564 | DOI:10.20524/aog.2020.0560 (Source: Pain Physician)
Source: Pain Physician - March 3, 2021 Category: Anesthesiology Authors: Antonio Tursi Marilisa Franceschi Walter Elisei Marcello Picchio Francesco Di Mario Giovanni Brandimarte Source Type: research

High Fat Diet Dysbiotic Mechanism of Decreased Gingival Blood Flow
In this study, we investigated the effect of high fat diet (HFD) on the onset of dysbiosis, gingival blood flow decreases, and the periodontal matrix remodeling. We established a dysbiosis model (HFD group) and probiotic model by Lactobacillus rhamnosus GG (LGG) treatment for 12weeks. Fecal samples were collected 24h before mice sacrificing, while short chain fatty acids (SCFA) analysis, DNA extraction, and sequencing for metagenomic analysis were performed afterwards. After sacrificing the animals, we collected periodontal tissues and conducted comprehensive morphological and genetic analyses. While HFD reduced Bacteroide...
Source: Frontiers in Physiology - March 3, 2021 Category: Physiology Source Type: research

No distinction in the gut microbiota between diarrhea predominant-irritable bowel syndrome and healthy subjects: matched case –control study in Thailand
ConclusionAlteration in the gut microbiota composition was probably not the main pathogenic mechanism in the Thai IBS-D patients assessed in this study. However, modifying microbiomes with potentially protective bacteria seems to be a beneficial therapy.Thai Clinical trial registry: TCTR20191211006, Date of registration: 10 Dec 2019. Retrospectively registered, Clinical trial URL:www.clinicaltrials.in.th (Source: Gut Pathogens)
Source: Gut Pathogens - March 3, 2021 Category: Microbiology Source Type: research

Probiotic Effector Compounds: Current Knowledge and Future Perspectives
Understanding the mechanism behind probiotic action will enable a rational selection of probiotics, increase the chances of success in clinical studies and make it easy to substantiate health claims. However, most probiotic studies over the years have rather focused on the effects of probiotics in health and disease, whereas little is known about the specific molecules that trigger effects in hosts. This makes it difficult to describe the detailed mechanism by which a given probiotic functions. Probiotics communicate with their hosts through molecular signaling. Meanwhile, since the molecules produced by probiotics under i...
Source: Frontiers in Microbiology - March 3, 2021 Category: Microbiology Source Type: research

Comprehensive Analysis of the Effect of Probiotic Intake by the Mother on Human Breast Milk and Infant Fecal Microbiota
CONCLUSION: This is the first Korean microbiome study in which the effect of different probiotic intake by the mother on the microbiota in HBM and IF samples was investigated. This study provides a cornerstone to further the understanding of the effect of probiotics on the mother and infant microbiomes.PMID:33650336 | DOI:10.3346/jkms.2021.36.e58 (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 2, 2021 Category: General Medicine Authors: Do Young Shin Jongsun Park Dae Yong Yi Source Type: research

Site-Directed Mutagenesis of Bifidobacterium Strains
Methods Mol Biol. 2021;2278:45-60. doi: 10.1007/978-1-0716-1274-3_5.ABSTRACTAt present, only a limited number of Bifidobacterium species are amenable to genetic manipulation using mutagenesis. This lack of genetic accessibility among the majority of bifidobacterial strains represents a significant roadblock for the study of gene function and expression in these potential probiotics. Genetic tools for generating mutants are difficult to develop for bifidobacteria, as they require workarounds for obstacles such as low transformation efficiencies, and the presence of differing and sometimes multiple restriction modification s...
Source: Mol Biol Cell - March 2, 2021 Category: Molecular Biology Authors: Kieran James Douwe van Sinderen Source Type: research

Comprehensive Analysis of the Effect of Probiotic Intake by the Mother on Human Breast Milk and Infant Fecal Microbiota
CONCLUSION: This is the first Korean microbiome study in which the effect of different probiotic intake by the mother on the microbiota in HBM and IF samples was investigated. This study provides a cornerstone to further the understanding of the effect of probiotics on the mother and infant microbiomes.PMID:33650336 | DOI:10.3346/jkms.2021.36.e58 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 2, 2021 Category: Biomedical Science Authors: Do Young Shin Jongsun Park Dae Yong Yi Source Type: research

Comprehensive Analysis of the Effect of Probiotic Intake by the Mother on Human Breast Milk and Infant Fecal Microbiota
CONCLUSION: This is the first Korean microbiome study in which the effect of different probiotic intake by the mother on the microbiota in HBM and IF samples was investigated. This study provides a cornerstone to further the understanding of the effect of probiotics on the mother and infant microbiomes.PMID:33650336 | PMC:PMC7921370 | DOI:10.3346/jkms.2021.36.e58 (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 2, 2021 Category: General Medicine Authors: Do Young Shin Jongsun Park Dae Yong Yi Source Type: research

Comprehensive Analysis of the Effect of Probiotic Intake by the Mother on Human Breast Milk and Infant Fecal Microbiota
CONCLUSION: This is the first Korean microbiome study in which the effect of different probiotic intake by the mother on the microbiota in HBM and IF samples was investigated. This study provides a cornerstone to further the understanding of the effect of probiotics on the mother and infant microbiomes.PMID:33650336 | PMC:PMC7921370 | DOI:10.3346/jkms.2021.36.e58 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - March 2, 2021 Category: Biomedical Science Authors: Do Young Shin Jongsun Park Dae Yong Yi Source Type: research

Therapeutic Effects of Probiotic Minas Frescal Cheese on the Attenuation of Ulcerative Colitis in a Murine Model
Inflammatory bowel diseases (IBDs) constitute disturbances of gastrointestinal tract that cause irreversible changes in the structure and function of tissues. Ulcerative colitis (UC), the most frequent IBD in the population, is characterized by prominent inflammation of the human colon. Functional foods containing probiotic bacteria have been studied as adjuvants to the treatment or prevention of IBDs. The selected probiotic strain Lactococcus lactis NCDO 2118 (L. lactis NCDO 2118) exhibits immunomodulatory effects, with promising results in UC mouse model induced by dextran sodium sulfate (DSS). Additionally, cheese is a ...
Source: Frontiers in Microbiology - March 2, 2021 Category: Microbiology Source Type: research

Manipulation of intestinal microbiome as potential treatment for insulin resistance and type 2 diabetes
ConclusionThere is an abundance of evidence suggesting a role for IM in the pathogenesis of IR and T2D based on reviewed studies using various methods to modulate IM and metabolites. However, the results are inconsistent. Future research should further assess this relationship. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - March 2, 2021 Category: Nutrition Source Type: research

Selection of probiotic Lactobacillus strains with antimicrobial activity to be used as biocontrol agents in food industry
Publication date: May 2021Source: LWT, Volume 143Author(s): S. Rodríguez-Sánchez, P. Fernández-Pacheco, S. Seseña, C. Pintado, M. Ll Palop (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - March 1, 2021 Category: Food Science Source Type: research

Cytotoxic Activity and Genotoxicity of Antioxidant WPC-hydrolysates and their Probiotics Compatibility as Potential Functional Feed Additive
Publication date: Available online 28 February 2021Source: Food BioscienceAuthor(s): María Belén Ballatore, Franco Matías Escobar, Yanina Estefanía Rossi, Marina del Rosario Bettiol, Cristina Vanesa Torres, Mariana Angélica Montenegro, Lilia Renée Cavaglieri (Source: Food Bioscience)
Source: Food Bioscience - March 1, 2021 Category: Food Science Source Type: research

Editorial: Lactic acid bacteria (probiotics), fermented milk and health
Publication date: Available online 28 February 2021Source: Food BioscienceAuthor(s): Giuseppe Spano (Source: Food Bioscience)
Source: Food Bioscience - March 1, 2021 Category: Food Science Source Type: research

Integrated Nutritional Supports for Diabetic Patients during COVID-19 Infection: A Comprehensive Review
CONCLUSION: There is an urgent need for healthy diet and integrated nutritional supports with home-based physical activities for diabetic patients during the self-isolation period of COVID-19 Infection.PMID:33645486 | DOI:10.2174/1573399817666210301103233 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 1, 2021 Category: Endocrinology Authors: A K Obidul Huq Abu Naim Mohammad Bazlur Rahim S M Golam Moktadir Ielias Uddin Mohammad Zahidul Manir Muhammad Abu Bakr Siddique Khaleda Islam Md Sirajul Islam Source Type: research

Probiotic Prescription Status of Pediatric Patients with Otitis Media Receiving Oral Amoxicillin or Amoxicillin/Clavulanate from April 2016 to March 2017 Using a Japanese Health Insurance Claims Database
Biol Pharm Bull. 2021;44(3):448-452. doi: 10.1248/bpb.b20-00214.ABSTRACTAntibiotic-associated diarrhea (AAD) is a typical side effect of antibiotic treatment, especially in children. Amoxicillin (AMPC) and amoxicillin/clavulanate (AMPC/CVA) are associated with high risk of AAD; however, these antibiotics are important in the pediatric field. Recent research suggests that probiotics prevent pediatric AAD, including that caused by AMPC and AMPC/CVA. Indeed, guidelines for acute otitis media in children recommend the concomitant use of probiotics. However, the prescription status of probiotics for pediatric patients with otit...
Source: Biological and Pharmaceutical Bulletin - March 1, 2021 Category: Drugs & Pharmacology Authors: Shungo Imai Kenji Momo Hitoshi Kashiwagi Takayuki Miyai Mitsuru Sugawara Yoh Takekuma Source Type: research

Molecular identification and functional analysis of MyD88 in giant freshwater prawn (Macrobrachium rosenbergii) and expression changes in response to bacterial challenge
In this study, the full-length cDNA of MyD88 from Macrobrachium rosenbergii (MRMyD88) was cloned. The MRMyD88 cDNA is 1758 bp long and contains a 1398-bp open reading frame. Multiple sequence alignment and phylogenetic analysis revealed that the amino acid sequence of MRMyD88 shared high identity with the known MyD88 proteins. The MRMyD88 mRNA was widely expressed in all examined tissues, with highest level in intestine, followed by gonad and pleopod. Furthermore, the MRMyD88 promoter region, spanning 1622 bp, contains several transcription factor-binding sites, including nine GATA-1 box motifs. Electrophoretic mobility sh...
Source: International Journal of Biological Macromolecules - March 1, 2021 Category: Biochemistry Authors: Quanxin Gao Qiongying Tang Zhenglong Xia Shaokui Yi Miuying Cai Houkuan Du Jie Yang Jingfen Li Qianqian Xing Jinping Luo Guoliang Yang Source Type: research

COVID-19: Immunology, Immunopathogenesis and Potential Therapies
Int Rev Immunol. 2021 Feb 27:1-36. doi: 10.1080/08830185.2021.1883600. Online ahead of print.ABSTRACTThe Coronavirus Disease-2019 (COVID-19) imposed public health emergency and affected millions of people around the globe. As of January 2021, 100 million confirmed cases of COVID-19 along with more than 2 million deaths were reported worldwide. SARS-CoV-2 infection causes excessive production of pro-inflammatory cytokines thereby leading to the development of "Cytokine Storm Syndrome." This condition results in uncontrollable inflammation that further imposes multiple-organ-failure eventually leading to death. SAR...
Source: International Reviews of Immunology - March 1, 2021 Category: Allergy & Immunology Authors: Asha Bhardwaj Leena Sapra Chaman Saini Zaffar Azam Pradyumna K Mishra Bhupendra Verma Gyan C Mishra Rupesh K Srivastava Source Type: research

Diversity and Composition of Gut Bacterial Community in Giant Panda with Anorexia
Curr Microbiol. 2021 Mar 1. doi: 10.1007/s00284-021-02424-w. Online ahead of print.ABSTRACTThe giant panda (GP) is the most precious animal in China. Gastrointestinal tract disease, especially associated with dysbiosis of gut microbiota, is the leading cause of death in GPs. Here, we performed 16S rRNA high-throughput sequencing to investigate the gut microbiota of GPs having symptoms of anorexia. Results showed that gut microbiota of GP with anorexia had lower richness (Chao1 index) than the healthy GP. However, no significant differences in alpha diversity were observed. There is a significance in the microbial structure...
Source: Current Microbiology - March 1, 2021 Category: Microbiology Authors: Siyue Zhao Caiwu Li Tao Zhu Lei Jin Wenwen Deng Ke Zhao Yongguo He Guo Li Yaowu Xiong Ti Li Bei Li Yan Huang Hemin Zhang Likou Zou Source Type: research

Integrated Nutritional Supports for Diabetic Patients during COVID-19 Infection: A Comprehensive Review
CONCLUSION: There is an urgent need for healthy diet and integrated nutritional supports with home-based physical activities for diabetic patients during the self-isolation period of COVID-19 Infection.PMID:33645486 | DOI:10.2174/1573399817666210301103233 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 1, 2021 Category: Endocrinology Authors: A K Obidul Huq Abu Naim Mohammad Bazlur Rahim S M Golam Moktadir Ielias Uddin Mohammad Zahidul Manir Muhammad Abu Bakr Siddique Khaleda Islam Md Sirajul Islam Source Type: research

Probiotic Prescription Status of Pediatric Patients with Otitis Media Receiving Oral Amoxicillin or Amoxicillin/Clavulanate from April 2016 to March 2017 Using a Japanese Health Insurance Claims Database
Biol Pharm Bull. 2021;44(3):448-452. doi: 10.1248/bpb.b20-00214.ABSTRACTAntibiotic-associated diarrhea (AAD) is a typical side effect of antibiotic treatment, especially in children. Amoxicillin (AMPC) and amoxicillin/clavulanate (AMPC/CVA) are associated with high risk of AAD; however, these antibiotics are important in the pediatric field. Recent research suggests that probiotics prevent pediatric AAD, including that caused by AMPC and AMPC/CVA. Indeed, guidelines for acute otitis media in children recommend the concomitant use of probiotics. However, the prescription status of probiotics for pediatric patients with otit...
Source: Biological and Pharmaceutical Bulletin - March 1, 2021 Category: Drugs & Pharmacology Authors: Shungo Imai Kenji Momo Hitoshi Kashiwagi Takayuki Miyai Mitsuru Sugawara Yoh Takekuma Source Type: research

Molecular identification and functional analysis of MyD88 in giant freshwater prawn (Macrobrachium rosenbergii) and expression changes in response to bacterial challenge
In this study, the full-length cDNA of MyD88 from Macrobrachium rosenbergii (MRMyD88) was cloned. The MRMyD88 cDNA is 1758 bp long and contains a 1398-bp open reading frame. Multiple sequence alignment and phylogenetic analysis revealed that the amino acid sequence of MRMyD88 shared high identity with the known MyD88 proteins. The MRMyD88 mRNA was widely expressed in all examined tissues, with highest level in intestine, followed by gonad and pleopod. Furthermore, the MRMyD88 promoter region, spanning 1622 bp, contains several transcription factor-binding sites, including nine GATA-1 box motifs. Electrophoretic mobility sh...
Source: International Journal of Biological Macromolecules - March 1, 2021 Category: Biochemistry Authors: Quanxin Gao Qiongying Tang Zhenglong Xia Shaokui Yi Miuying Cai Houkuan Du Jie Yang Jingfen Li Qianqian Xing Jinping Luo Guoliang Yang Source Type: research

COVID-19: Immunology, Immunopathogenesis and Potential Therapies
Int Rev Immunol. 2021 Feb 27:1-36. doi: 10.1080/08830185.2021.1883600. Online ahead of print.ABSTRACTThe Coronavirus Disease-2019 (COVID-19) imposed public health emergency and affected millions of people around the globe. As of January 2021, 100 million confirmed cases of COVID-19 along with more than 2 million deaths were reported worldwide. SARS-CoV-2 infection causes excessive production of pro-inflammatory cytokines thereby leading to the development of "Cytokine Storm Syndrome." This condition results in uncontrollable inflammation that further imposes multiple-organ-failure eventually leading to death. SAR...
Source: International Reviews of Immunology - March 1, 2021 Category: Allergy & Immunology Authors: Asha Bhardwaj Leena Sapra Chaman Saini Zaffar Azam Pradyumna K Mishra Bhupendra Verma Gyan C Mishra Rupesh K Srivastava Source Type: research

Diversity and Composition of Gut Bacterial Community in Giant Panda with Anorexia
Curr Microbiol. 2021 Mar 1. doi: 10.1007/s00284-021-02424-w. Online ahead of print.ABSTRACTThe giant panda (GP) is the most precious animal in China. Gastrointestinal tract disease, especially associated with dysbiosis of gut microbiota, is the leading cause of death in GPs. Here, we performed 16S rRNA high-throughput sequencing to investigate the gut microbiota of GPs having symptoms of anorexia. Results showed that gut microbiota of GP with anorexia had lower richness (Chao1 index) than the healthy GP. However, no significant differences in alpha diversity were observed. There is a significance in the microbial structure...
Source: Current Microbiology - March 1, 2021 Category: Microbiology Authors: Siyue Zhao Caiwu Li Tao Zhu Lei Jin Wenwen Deng Ke Zhao Yongguo He Guo Li Yaowu Xiong Ti Li Bei Li Yan Huang Hemin Zhang Likou Zou Source Type: research

Integrated Nutritional Supports for Diabetic Patients during COVID-19 Infection: A Comprehensive Review
CONCLUSION: There is an urgent need for healthy diet and integrated nutritional supports with home-based physical activities for diabetic patients during the self-isolation period of COVID-19 Infection.PMID:33645486 | DOI:10.2174/1573399817666210301103233 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 1, 2021 Category: Endocrinology Authors: A K Obidul Huq Abu Naim Mohammad Bazlur Rahim S M Golam Moktadir Ielias Uddin Mohammad Zahidul Manir Muhammad Abu Bakr Siddique Khaleda Islam Md Sirajul Islam Source Type: research

Probiotic Prescription Status of Pediatric Patients with Otitis Media Receiving Oral Amoxicillin or Amoxicillin/Clavulanate from April 2016 to March 2017 Using a Japanese Health Insurance Claims Database
Biol Pharm Bull. 2021;44(3):448-452. doi: 10.1248/bpb.b20-00214.ABSTRACTAntibiotic-associated diarrhea (AAD) is a typical side effect of antibiotic treatment, especially in children. Amoxicillin (AMPC) and amoxicillin/clavulanate (AMPC/CVA) are associated with high risk of AAD; however, these antibiotics are important in the pediatric field. Recent research suggests that probiotics prevent pediatric AAD, including that caused by AMPC and AMPC/CVA. Indeed, guidelines for acute otitis media in children recommend the concomitant use of probiotics. However, the prescription status of probiotics for pediatric patients with otit...
Source: Biological and Pharmaceutical Bulletin - March 1, 2021 Category: Drugs & Pharmacology Authors: Shungo Imai Kenji Momo Hitoshi Kashiwagi Takayuki Miyai Mitsuru Sugawara Yoh Takekuma Source Type: research

COVID-19: Immunology, Immunopathogenesis and Potential Therapies
Int Rev Immunol. 2021 Feb 27:1-36. doi: 10.1080/08830185.2021.1883600. Online ahead of print.ABSTRACTThe Coronavirus Disease-2019 (COVID-19) imposed public health emergency and affected millions of people around the globe. As of January 2021, 100 million confirmed cases of COVID-19 along with more than 2 million deaths were reported worldwide. SARS-CoV-2 infection causes excessive production of pro-inflammatory cytokines thereby leading to the development of "Cytokine Storm Syndrome." This condition results in uncontrollable inflammation that further imposes multiple-organ-failure eventually leading to death. SAR...
Source: International Reviews of Immunology - March 1, 2021 Category: Allergy & Immunology Authors: Asha Bhardwaj Leena Sapra Chaman Saini Zaffar Azam Pradyumna K Mishra Bhupendra Verma Gyan C Mishra Rupesh K Srivastava Source Type: research

Probiotics for the Management of Infantile Colic: A Systematic Review
Background: Colic is defined as periods of inconsolable crying, fussing, or irritability that have no apparent cause and present in healthy infants under 5 months of age. Although colic is a benign and self-limiting condition, it can be distressing to parents and there are few robust treatment interventions. This systematic review explored the evidence for administration of probiotics to prevent or decrease symptoms of colic. Methods: Literature searches were conducted in PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Cochrane Library, and Web of Science. Sample: Twenty article...
Source: MCN: The American Journal of Maternal Child Nursing - March 1, 2021 Category: Nursing Tags: Feature: NCPD Connection Source Type: research

Probiotics for the Management of Infantile Colic: A Systematic Review
No abstract available (Source: MCN: The American Journal of Maternal Child Nursing)
Source: MCN: The American Journal of Maternal Child Nursing - March 1, 2021 Category: Nursing Tags: NCPD Connection Source Type: research

S-Layer From Lactobacillus brevis Modulates Antigen-Presenting Cell Functions via the Mincle-Syk-Card9 Axis
In this study, we identified Mincle as a receptor for the Surface (S)-layer of the probiotic bacteria Lactobacillus brevis modulating GM-CSF bone marrow-derived cells (BMDCs) functions. We found that the S-layer/Mincle interaction led to a balanced cytokine response in BMDCs by triggering the release of both pro- and anti-inflammatory cytokines. In contrast, BMDCs derived from Mincle−/−, CARD9−/− or conditional Syk−/− mice failed to maintain this balance, thus leading to an increased production of the pro-inflammatory cytokines TNF and IL-6, whereas the levels of the anti-inflammatory cy...
Source: Frontiers in Immunology - March 1, 2021 Category: Allergy & Immunology Source Type: research

Factors Associated With the Microbiome in Moderate –Late Preterm Babies: A Cohort Study From the DIAMOND Randomized Controlled Trial
In this study, we collected fecal samples at Day-10 (D10) and 4-months corrected-age (4M) from 227 moderate–late preterm (MLPT) babies enrolled in a randomized controlled trial of nutritional management. A total of 320 samples underwent 16S amplicon sequencing, and shotgun metagenomic sequencing was performed on 94 samples from the 4M time point. The microbiome of babies whose families lived in lower socioeconomic status (SES) areas exhibited a significantly higher microbial alpha diversity at D10 (Wilcoxon test, p = 0.021), greater abundance of Bifidobacterium (linear model, q = 0.020) at D10 and Megasphaera (q = 0....
Source: Frontiers in cellular and infection microbiology - March 1, 2021 Category: Microbiology Source Type: research

The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial
. (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - February 28, 2021 Category: Nutrition Authors: Jalal Moludi Hamed Khedmatgozar Seyed Mostafa Nachvak Hadi Abdollahzad Mehdi Moradinazar Ali Sadeghpour tabaei Source Type: research

Response of the ileum transcriptome to probiotic and fructo-oligosaccharides in Taiping chicken
In this study, we used RNA-Seq analysis to study the gene expression in ileum tissue after Taiping chicken was given probiotics and fructo-oligosaccharides. In total, 67 genes were differentially expressed in the ileum. Ten of the differently expressed genes were further validated by RT-qPCR. In addition, these differentially expressed genes were mainly enriched to tyrosine metabolism, AGE-RAGE signaling pathway in diabetic complications, phenylalanine metabolism, and pyrimidine metabolism. The results which this study provides contribute to our understanding application of probiotics and fructo-oligosaccharides in indigen...
Source: J Appl Genet - February 27, 2021 Category: Genetics & Stem Cells Authors: Lintong Luo Fang Ma Qianning Wang Source Type: research

Complex microbial communities inhabiting natural Cordyceps militaris and the habitat soil and their predicted functions
In this study, our objective was to reveal the microbial communities that inhabit C. militaris and analyze their potential functions. High-throughput sequencing of 16S rRNA and ITS genes was used to compare the diversity and composition of the bacterial and fungal communities associated with naturally occurring C. militaris collected from Yunnan Province, southwestern China. The diversity and richness of the microbial communities and the number of function genes of the bacteria were significantly higher in the habitat soil than in the fruiting body. The sclerotia and stromata samples shared the same microbiota and function...
Source: Antonie van Leeuwenhoek - February 27, 2021 Category: Microbiology Authors: Xiao-Mei Zhang De-Xiang Tang Qing-Qing Li Yuan-Bing Wang Zhi-Hong Xu Wen-Jun Li Hong Yu Source Type: research

Response of the ileum transcriptome to probiotic and fructo-oligosaccharides in Taiping chicken
In this study, we used RNA-Seq analysis to study the gene expression in ileum tissue after Taiping chicken was given probiotics and fructo-oligosaccharides. In total, 67 genes were differentially expressed in the ileum. Ten of the differently expressed genes were further validated by RT-qPCR. In addition, these differentially expressed genes were mainly enriched to tyrosine metabolism, AGE-RAGE signaling pathway in diabetic complications, phenylalanine metabolism, and pyrimidine metabolism. The results which this study provides contribute to our understanding application of probiotics and fructo-oligosaccharides in indigen...
Source: J Appl Genet - February 27, 2021 Category: Genetics & Stem Cells Authors: Lintong Luo Fang Ma Qianning Wang Source Type: research

Response of the ileum transcriptome to probiotic and fructo-oligosaccharides in Taiping chicken
In this study, we used RNA-Seq analysis to study the gene expression in ileum tissue after Taiping chicken was given probiotics and fructo-oligosaccharides. In total, 67 genes were differentially expressed in the ileum. Ten of the differently expressed genes were further validated by RT-qPCR. In addition, these differentially expressed genes were mainly enriched to tyrosine metabolism, AGE-RAGE signaling pathway in diabetic complications, phenylalanine metabolism, and pyrimidine metabolism. The results which this study provides contribute to our understanding application of probiotics and fructo-oligosaccharides in indigen...
Source: J Appl Genet - February 27, 2021 Category: Genetics & Stem Cells Authors: Lintong Luo Fang Ma Qianning Wang Source Type: research

Complete genome sequencing of Peyer ’s patches-derived Lactobacillus taiwanensis CLG01, a potential probiotic with antibacterial and immunomodulatory activity
The genus Lactobacillus is an important component of the gastrointestinal tract of human and animals and commonly considered as probiotic. L. taiwanensis has long been proposed to be a probiotic whereas understan... (Source: BMC Microbiology)
Source: BMC Microbiology - February 27, 2021 Category: Microbiology Authors: Xiao-yu Li, Li-xiang Li, Yan Li, Ru-chen Zhou, Bing Li, Xiang Gu, Shi-chen Fu, Bi-ying Jin, Xiu-li Zuo and Yan-qing Li Tags: Research article Source Type: research

The Gut Microbiome of Dogs and Cats, and the Influence of Diet
The gut microbiome is a functional organ, and responds metabolically to the nutrient composition within the diet. Fiber, starch, and protein content have strong effects on the microbiome composition, and changes in these nutrient profiles can induce rapid shifts. Due to functional redundancy of bacteria within microbial communities, important metabolites for health can be produced by different bacteria. Microbiome alterations associated with disease are of greater magnitude than those seen in healthy dogs on different diets. Dietary changes, addition of prebiotics, and probiotics, can be beneficial to improve microbial div...
Source: Veterinary Clinics of North America: Small Animal Practice - February 27, 2021 Category: Veterinary Research Authors: Rachel Pilla, Jan S. Suchodolski Source Type: research

Corrigendum to: “Effects of fructans and probiotics on the inhibition of Klebsiella oxytoca and the production of short-chain fatty acids assessed by NMR spectroscopy” [Carbohyd. Polym. 248 (2020) 116832, doi: 10.1016/j.carbpol.2020.116832]
Publication date: 15 May 2021Source: Carbohydrate Polymers, Volume 260Author(s): Bruna Higashi, Tamara Borges Mariano, Benício Alves de Abreu Filho, Regina Aparecida Correia Gonçalves, Arildo José Braz de Oliveira (Source: Carbohydrate Polymers)
Source: Carbohydrate Polymers - February 26, 2021 Category: Biomedical Science Source Type: research

Molecules, Vol. 26, Pages 1249: Probiotics in Cosmetic and Personal Care Products: Trends and Challenges
eid Probiotics, defined as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host,” are becoming increasingly popular and marketable. However, too many of the products currently labelled as probiotics fail to comply with the defining characteristics. In recent years, the cosmetic industry has increased the number of products classified as probiotics. While there are several potential applications for probiotics in personal care products, specifically for oral, skin, and intimate care, proper regulation of the labelling and marketing standards is still required ...
Source: Molecules - February 26, 2021 Category: Chemistry Authors: Scarlett Puebla-Barragan Gregor Reid Tags: Review Source Type: research

Low Bifidobacterium Abundance in the Lower Gut Microbiota Is Associated With Helicobacter pylori-Related Gastric Ulcer and Gastric Cancer
Helicobacter pylori infection in stomach leads to gastric cancer, gastric ulcer, and duodenal ulcer. More than 1 million people die each year due to these diseases, but why most H. pylori-infected individuals remain asymptomatic while a certain proportion develops such severe gastric diseases remained an enigma. Several studies indicated that gastric and intestinal microbiota may play a critical role in the development of the H. pylori-associated diseases. However, no specific microbe in the gastric or intestinal microbiota has been clearly linked to H. pylori infection and related gastric diseases. Here, we studied H. pyl...
Source: Frontiers in Microbiology - February 26, 2021 Category: Microbiology Source Type: research

Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body
Hosting millions of microorganisms, the digestive tract is the primary and most important part of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant bacterial population inside intestinal tissues may face potential health problems such as inflammation and infections. Therefore, the immune system has evolved to sustain the host–microbiota symbiotic relationship. On the other hand, to maintain host immune homeostasis, the intestinal microflora often exerts an immunoregulatory function that cannot be ignored. A field of great interest is the association of either microbiota or pro...
Source: Frontiers in Immunology - February 26, 2021 Category: Allergy & Immunology Source Type: research

Lacticaseibacillus casei SJRP38 and buriti pulp increased bioactive compounds and probiotic potential of fermented milk
Publication date: May 2021Source: LWT, Volume 143Author(s): Tais Fernanda Borgonovi, Sabrina Neves Casarotti, Ana Lúcia Barretto Penna (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - February 25, 2021 Category: Food Science Source Type: research

Corrigendum to "Clinical Trials of Probiotic Strains in Selected Disease Entities"
Int J Microbiol. 2021 Feb 11;2021:7356890. doi: 10.1155/2021/7356890. eCollection 2021.ABSTRACT[This corrects the article DOI: 10.1155/2020/8854119.].PMID:33628258 | PMC:PMC7895583 | DOI:10.1155/2021/7356890 (Source: International Journal of Microbiology)
Source: International Journal of Microbiology - February 25, 2021 Category: Microbiology Authors: Ruth Dudek-Wicher Adam Junka Justyna Paleczny Marzenna Bartoszewicz Source Type: research

Antidepressants for Older People, Point-of-Care Ultrasonograpy, BRCA Testing, Probiotics
Am Fam Physician. 2021 Mar 1;103(5):270.NO ABSTRACTPMID:33630541 (Source: American Family Physician)
Source: American Family Physician - February 25, 2021 Category: Primary Care Source Type: research