Aflatoxins biodetoxification strategies based on probiotic bacteria.
Abstract Aflatoxins are secondary metabolites of fungi that are the most dangerous mycotoxin and food safety challenges. Human exposure to mycotoxins occurs directly throughout the intake of contaminated agricultural products or indirectly throughout the consumption of products prepared with animal origin or obtained from animals that were fed with contaminated material. For detoxification and reducing threats to public health and the economic damage caused by the aflatoxins in animal and plants food products, different techniques (physical, chemical and biological) has been studied. All of these methods, by modif...
Source: Toxicon - April 8, 2020 Category: Toxicology Authors: Afshar P, Shokrzadeh M, Raeisi SN, Ghorbani-HasanSaraei A, Nasiraii LR Tags: Toxicon Source Type: research

Dietary administration effects of exopolysaccharide from potential probiotic strains on immune and antioxidant status and nutritional value of European sea bass (Dicentrarchus labrax L.)
Publication date: Available online 6 April 2020Source: Research in Veterinary ScienceAuthor(s): Abdelkarim Mahdhi, Ibtissem Chakroun, Cristóbal Espinosa Ruiz, Concetta Maria Messina, Rosaria Arena, Hatem Majdoub, Andrea Santulli, Ridha Mzoughi, Maria Angeles Esteban (Source: Research in Veterinary Science)
Source: Research in Veterinary Science - April 7, 2020 Category: Veterinary Research Source Type: research

Bifidobacterium infantis Relieves Allergic Asthma in Mice by Regulating Th1/Th2.
CONCLUSIONS B. infantis can reduce the infiltration of inflammatory cells induced by OVA-specific antibodies in mice. B. infantis has therapeutic effects on allergic asthma by promoting Th1 and inhibiting Th2 immune responses. PMID: 32249275 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - April 7, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Proof-of-concept trial of the combination of lactitol with Bifidobacterium bifidum and Lactobacillus acidophilus for the eradication of intestinal OXA-48-producing Enterobacteriaceae
ConclusionsThe combination of prebiotics and probiotics was well tolerated. A rapid reduction on the OXA-PE intestinal loads was observed. At the EoT, decolonization was achieved in three patients.Clinical Trials Registration: NCT02307383. EudraCT Number: 2014-000449-65. (Source: Gut Pathogens)
Source: Gut Pathogens - April 7, 2020 Category: Microbiology Source Type: research

Probiotic: conceptualization from a new approach
Publication date: Available online 5 April 2020Source: Current Opinion in Food ScienceAuthor(s): Fatemeh Zendeboodi, Nasim Khorshidian, Amir M Mortazavian, Adriano G da Cruz (Source: Current Opinion in Food Science)
Source: Current Opinion in Food Science - April 6, 2020 Category: Food Science Source Type: research

Peripheral Immunosenescence and Central Neuroinflammation: A Dangerous Liaison. A Dietary Approach.
CONCLUSION: Ageing is characterized by a peripheral subversion of the immune system with a condition of inflamm-ageing. Neuroinflammation and neurodegenerative diseases seem to be a central manifestation of a peripheral perturbation of the immune machinery. Dietary products and nutraceuticals may lead to a down-regulation of the oxidative and pro-inflammatory profile in ageing. PMID: 32250234 [PubMed - as supplied by publisher] (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 6, 2020 Category: Endocrinology Authors: Magrone T, Magrone M, Russo MA, Jirillo E Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

The anti-inflammatory, anti-oxidant and protective effects of probiotic mixture on organ toxicity in a rat model
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - April 6, 2020 Category: Microbiology Authors: Murat Karamese Hakan Aydin Volkan Gelen Emin Sengul Selina Aksak Karamese Source Type: research

Molecules, Vol. 25, Pages 1674: Hepcidin and Erythroferrone Correlate with Hepatic Iron Transporters in Rats Supplemented with Multispecies Probiotics
burska The influence of probiotic supplementation on iron metabolism remains poorly investigated. However, a range of studies, especially on Lactobacillus plantarum 299v (Lp229v), have indicated a possible positive impact of probiotics on iron absorption. The aim of the study was to determine the effect of multistrain probiotic supply on iron balance. Thirty Wistar rats were randomized into three groups: placebo (KK group), and multistrain probiotic per os in a daily dose of 2.5 × 109 colony forming units (CFU) (PA group) or 1 × 1010 CFU (PB group). Multistrain probiotic consisted of nine ba...
Source: Molecules - April 5, 2020 Category: Chemistry Authors: Katarzyna Skrypnik Pawe ł Bogdański Magdalena Sobieska Joanna Suliburska Tags: Article Source Type: research

Probiotic Lactobacillus strains from Mongolia improve calcium transport and uptake by intestinal cells in vitro
Publication date: July 2020Source: Food Research International, Volume 133Author(s): Cyril Raveschot, François Coutte, Marc Frémont, Maxime Vaeremans, Jamyan Dugersuren, Shirchin Demberel, Djamel Drider, Pascal Dhulster, Christophe Flahaut, Benoit Cudennec (Source: Food Research International)
Source: Food Research International - April 4, 2020 Category: Food Science Source Type: research

Lactobacillus rhamnosus sepsis associated with probiotic therapy in an extremely preterm infant: pathogenesis and a review for clinicians
Publication date: Available online 3 April 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Ming-Chou Chiang, Chyi-Liang Chen, Ye Feng, Chien-Chang Chen, Reyin Lien, Cheng-Hsun Chiu (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - April 4, 2020 Category: Microbiology Source Type: research

Probiotic Validation of a Non-native, Thermostable, Phytase-Producing Bacterium: Streptococcus thermophilus.
Abstract Phytate-linked nutritional deficiency disorders have plagued poultry for centuries. The application of exogenous phytases in poultry feed has served as a solution to this problem. However, they are linked to certain limitations which include thermal instability during prolonged feed processing. Therefore, in this study, Streptococcus thermophilus 2412 based phytase stability was assessed at higher temperatures up to 90 °C. This was followed by probiotic validation of the same bacterium in an in vitro intestinal model. Bacterial phytase showed thermostability up to 70 °C with a recorded a...
Source: Current Microbiology - April 4, 2020 Category: Microbiology Authors: Priyodip P, Balaji S Tags: Curr Microbiol Source Type: research

Breast Milk and Microbiota in the Premature Gut: A Method of Preventing Necrotizing Enterocolitis.
Authors: Walker WA, Meng D Abstract Necrotizing enterocolitis (NEC) is a devastating inflammatory condition of the intestine, which affects premature infants and causes untold damage. Its pathogenesis has to do with how colonizing bacteria interact with the immature newborn intestine. An immature innate immune response with increased TLR-4 on the cell surface and increased signaling molecules, such as NF-κB, can cause excessive inflammation. This is in conjunction with a decrease in the appearance of regulatory molecules which effect the control of innate responses. This condition is so devastating that it mu...
Source: Nestlee Nutrition Institute Workshop Series - April 3, 2020 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract
The intestinal tract is the largest digestive organ in the human body. It is colonized by, and consistently exposed to, a myriad of microorganisms, including bifidobacteria, lactobacillus, Escherichia coli, enterococcus, clostridium perfringens, and pseudomonas. To protect the body from potential pathogens, the intestinal tract has evolved regional immune characteristics. These characteristics are defined by its unique structure, function, and microenvironment, which differ drastically from those of the common central and peripheral immune organs. The intestinal microenvironment created by the intestinal flora and its prod...
Source: Frontiers in Immunology - April 3, 2020 Category: Allergy & Immunology Source Type: research

Efficacy and Safety of Probiotics in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis
BackgroundIrritable bowel syndrome is a functional gastrointestinal disease. Evidence has suggested that probiotics may benefit IBS symptoms. However, clinical trials remain conflicting.AimsTo implement a systematic review and meta-analysis of clinical trials regarding the efficacy and safety of probiotics for IBS patients.MethodsWe searched for relevant trials in Medline(1966 to Jan 2019), Embase(1974 to Jan 2019), the Cochrane Central Register of Controlled Trials(up to Jan 2019), the ClinicalTrials.gov trials register(up to Jan 2019), and Chinese Biomedical Literature Database(1978 to Jan 2019). Risk ratio (RR) and a 95...
Source: Frontiers in Pharmacology - April 3, 2020 Category: Drugs & Pharmacology Source Type: research

Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for treatment of upper respiratory tract infections in children: a pilot study on short-term efficacy
AbstractBackgroundRecurrent respiratory infections (RRIs) are defined by the presence of at least one of the following criteria: (i)>  6 annual respiratory infections (RIs); (ii)>  1 monthly RIs involving the upper airways from September to April; (iii)>  3 annual RIs involving the lower airways represent a very common health problem in the first years of life. We conducted a multi-centre, prospective, single-open study to assess the efficacy and the safety ofStreptococcus salivarius 24SMBc andStreptococcus oralis 89a in the prevention of upper respiratory tract infections (URTIs) in children....
Source: Italian Journal of Pediatrics - April 3, 2020 Category: Pediatrics Source Type: research

Lactobacillus Casei Zhang Alleviates Shrimp Tropomyosin ‐Induced Food Allergy by Switching Antibody Isotypes Through the NF‐κB‐Dependent Immune Tolerance
ConclusionThis work indicated the ability of LcZ to alleviate TM ‐induced food allergy and demonstrated the involvement of the tolerogenic immune cells and NF‐κB signaling pathway, indicating LcZ to be a potential immunomodulator and immunotherapy assistor.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 3, 2020 Category: Food Science Authors: Linglin Fu, Menghua Xie, Chong Wang, Yi Qian, Jianjian Huang, Zhihong Sun, Heping Zhang, Yanbo Wang Tags: Research Article Source Type: research

Probiotic Lactobacillus Rhamnosus GG Protects Against P. Gingivalis And F. Nucleatum Gut Dysbiosis.
CONCLUSION: P. gingivalis and F. nucleatum inoculation induced significant changes in intestinal inflammation and caecal microbiome. Oral gavage with LGG exerted a protective effect against intestinal inflammation and limited gut microbiome changes associated with P. gingivalis and F. nucleatum. PMID: 32224547 [PubMed - in process] (Source: Journal of the International Academy of Periodontology)
Source: Journal of the International Academy of Periodontology - April 2, 2020 Category: Dentistry Tags: J Int Acad Periodontol Source Type: research

Does Streptococcus Salivarius Strain M18 Assumption Make Black Stains Disappear in Children?
Conclusions: BSs formation in children could be prevented by administering S. salivarius M18. (Source: Oral health and Preventive dentistry)
Source: Oral health and Preventive dentistry - April 2, 2020 Category: Dentistry Source Type: research

A Systematic Review and Meta-analysis of Clinical, Immunological, and Microbiological Shift in Periodontitis After Nonsurgical Periodontal Therapy With Adjunctive Use of Probiotics
Publication date: Available online 23 January 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Sze Nga Ho, Aneesha Acharya, Sangamithra Sidharthan, Kar Yan Li, Wai Keung Leung, Colman McGrath, Georgios Pelekos (Source: Journal of Evidence Based Dental Practice)
Source: Journal of Evidence Based Dental Practice - April 2, 2020 Category: Dentistry Source Type: research

An aqueous extract of a Bifidobacterium species induces apoptosis and inhibits invasiveness of non-small cell lung cancer cells.
This study analyzed the anticancer effects of aqueous extracts of probiotic bacteria Bifidobacterium bifidum (BB), Bifidobacterium longum (BL), Bifidobacterium lactis (BLA), Bifidobacterium infantis 1 (BI1), and Bifidobacterium infantis 2 (BI2) on NSCLC cell lines. When the aqueous extracts of probiotic Bifidobacterium species were applied to the NSCLC cell lines A549, H1299, and HCC827, cell death increased considerably; in particular, the aqueous extracts from BB and BLA markedly reduced cell proliferation. p38 phosphorylation induced by BB aqueous extract increased the expression of cleaved caspase 3 and cleaved poly (A...
Source: Journal of Microbiology and Biotechnology - April 2, 2020 Category: Biotechnology Authors: An J, Kim HS, Yang KM Tags: J Microbiol Biotechnol Source Type: research

Correction to: Genetic and Phenotypic Characteristics of a Multi-strain Probiotic for Broilers.
Abstract The authors would like to correct the errors in the publication of the original article. PMID: 32240340 [PubMed - as supplied by publisher] (Source: Current Microbiology)
Source: Current Microbiology - April 2, 2020 Category: Microbiology Authors: Neveling DP, Ahire JJ, Laubscher W, Rautenbach M, Dicks LMT Tags: Curr Microbiol Source Type: research

Crystal structure of monomeric Amuc_1100 from Akkermansia muciniphila
This study provides a structural basis for the elucidation of the molecular mechanism of Amuc_1100. (Source: Acta Crystallographica Section F)
Source: Acta Crystallographica Section F - April 1, 2020 Category: Biochemistry Authors: Mou, L. Peng, X. Chen, Y. Xiao, Q. Liao, H. Liu, M. Guo, L. Liu, Y. Zhang, X. Deng, D. Tags: Akkermansia muciniphila type IV pili Amuc_1100 gut microbes crystal structure research communications Source Type: research

Probiotics to Augment Antifungal Treatment of Vulvovaginal Candidiasis.
PMID: 32227830 [PubMed - in process] (Source: American Family Physician)
Source: American Family Physician - April 1, 2020 Category: Primary Care Authors: Kopicki R, Chang JT, Kelsberg G, Safranek S Tags: Am Fam Physician Source Type: research

Comparative proteomic analysis reveals metabolic variability of probiotic Enterococcus durans during aerobic and anaerobic cultivation.
This study showed that E. durans LAB18S growing on FOS was stimulated to produce clinically important biomolecules, including proteins that have been investigated as potential antineoplastic agents. Significance: The probiotic strain E. durans LAB18S produce clinically relevant enzymes for the treatment of cancer when cultivated in symbiosis with fructo-oligosacchrides (FOS). In addition, proteins associated with cellular multiplication, cell wall integrity and resistance, and H2O2 detoxification were induced under anaerobic growth. These characteristics could be relevant to support maintenance of intestinal health. P...
Source: Journal of Proteomics - April 1, 2020 Category: Biochemistry Authors: Comerlato CB, Zhang X, Walker K, Brandelli A, Figeys D Tags: J Proteomics Source Type: research

Highly alkali-stable and cellulase-free xylanases from Fusarium sp. 21 and their application in clarification of orange juice.
Abstract Xylanase is a versatile tool in the food, fiber biobleaching and biofuel industries. Here, to discover new enzyme with special properties, we cloned three xylanases (Xyn11A, Xyn11B, and Xyn11C) by mining the genome of the xylanase producing fungus strain Fusarium sp. 21, biochemically characterized these enzyme and explored their potential application in juice processing. Both Xyn11A and Xyn11B had an optimal pH of 6.0 and optimal temperature of 45 °C, and retained>90% of the residual activity at pH range of 5-10.5 for 24 h. Xyn11C displayed the maximum activity at pH 5.0 and 45 °C and ...
Source: International Journal of Biological Macromolecules - April 1, 2020 Category: Biochemistry Authors: Li C, Kumar A, Luo X, Shi H, Liu Z, Wu G Tags: Int J Biol Macromol Source Type: research

Gut microbiota and therapeutic approaches for dysbiosis in irritable bowel syndrome: Recent developments and future perspectives.
Authors: Dale HF, Lied GA Abstract Increased knowledge regarding the implications of gut microbiota in irritable bowel syndrome (IBS), suggest that a disturbed intestinal microenvironment (dysbiosis) might promote the development and maintenance of IBS symptoms and effects several pathways in the pathology of this multifactorial disease. Accordingly, manipulation of the gut microbiota in order to improve IBS symptoms has the last decade evolved as a novel treatment strategy. Several different approaches have been investigated in order to improve the gut microbiota composition. Dietary modifications including supple...
Source: Turkish Journal of Medical Sciences - March 31, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Systematic review of the effect of probiotics on experimental gingivitis in humans
Abstract: Probiotic therapy is a viable alternative to chlorhexidine, a widely used antiseptic in dentistry that produces significant adverse effects. This systematic review aimed to analyze the effects of probiotics on experimental gingivitis in humans. Two independent reviewers conducted a comprehensive literature search until March 2019. Randomized clinical trials and controlled clinical trials were selected. Outcome data were extracted and critically analyzed. A total of five articles were included in the qualitative synthesis. No meta-analysis could be conducted due to the heterogeneity of the selected studies. The us...
Source: Brazilian Oral Research - March 31, 2020 Category: Dentistry Source Type: research

Effect of fermentation in nutritional, textural and sensorial parameters of vegan-spread products using a probiotic folate-producing Lactobacillus sakei strain
Publication date: Available online 30 March 2020Source: LWTAuthor(s): Ana Laura Mosso, Jean Guy LeBlanc, Isabel Castanheira, Pablo Ribotta, Norma Sammán (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - March 31, 2020 Category: Food Science Source Type: research

Exploring the Potential for Fungal Antagonism and Cell Wall Attack by Bacillus subtilis natto
To develop more ecologically sustainable agricultural practices requires that we reduce our reliance on synthetic chemical pesticides for crop protection. This will likely involve optimized biocontrol approaches – the use of beneficial soil microbes to attack potential plant pathogens to protect plants from diseases. Many bacterial species, including strains of Bacillus subtilis, have been explored for their biocontrol properties, as they can control the growth of harmful fungi, often by disrupting the fungal cell wall. A strain that is not often considered for this particular application is Bacillus subtilis natto, ...
Source: Frontiers in Microbiology - March 31, 2020 Category: Microbiology Source Type: research

Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
CONCLUSIONS: We found low-certainty evidence from studies of good methodological quality that lactoferrin supplementation of enteral feeds decreases late-onset sepsis but not NEC ≥ stage II or 'all cause mortality' or neurodevelopmental outcomes at 24 months of age in preterm infants without adverse effects. Low- to very low-certainty evidence suggests that lactoferrin supplementation of enteral feeds in combination with probiotics decreases late-onset sepsis and NEC ≥ stage II in preterm infants without adverse effects, however, there were few included studies of poor methodological quality. The presence of publicat...
Source: Cochrane Database of Systematic Reviews - March 31, 2020 Category: General Medicine Authors: Pammi M, Suresh G Tags: Cochrane Database Syst Rev Source Type: research

Advances in understanding the potential therapeutic applications of gut microbiota and probiotic mediated therapies in celiac disease.
Authors: Francavilla R, Cristofori F, Vacca M, Barone M, De Angelis M Abstract Introduction: Celiac Disease (CD) is an autoimmune enteropathy caused by exposure to gluten in genetically predisposed people. While gluten is the main driving force in CD, evidence has shown that microbiota might be involved in the pathogenesis, development, and clinical presentation of CD. Microbiota manipulation may modify its functional capacity and may be crucial for setting-up potential preventive or therapeutic application. Moreover, probiotics are an excellent source of endopeptidases for digesting gluten.Areas covered: In this n...
Source: Expert Review of Gastroenterology and Hepatology - March 30, 2020 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Cottonseed meal fermented by Candida tropical reduces the fat deposition in white-feather broilers through cecum bacteria-host metabolic cross-talk.
Abstract In the present study, effects of cottonseed meal fermented by Candida tropicalis (FCSM) on fat deposition, cecum microbiota, and metabolites and their interactions were studied in broilers. A total of 180 1-day-old broilers were randomly assigned into two groups with six replicates of 15 birds in each. The birds were offered two diets consisted one control, i.e., supplemented with 0% FCSM (CON) and an experimental, with 6% FCSM (FCSM). Illumina MiSeq sequencing and liquid chromatography-mass spectrometry were used to investigate the profile changes of the cecum microbes and metabolites and the interaction...
Source: Applied Microbiology and Biotechnology - March 30, 2020 Category: Microbiology Authors: Niu J, Zhang J, Wei L, Ma X, Zhang W, Nie C Tags: Appl Microbiol Biotechnol Source Type: research

Association of oral dysbiosis with oral cancer development.
Authors: La Rosa GRM, Gattuso G, Pedullà E, Rapisarda E, Nicolosi D, Salmeri M Abstract Oral squamous cell carcinoma (OSCC) is the leading cause of mortality for oral cancer. Numerous risk factors mainly related to unhealthy habits and responsible for chronic inflammation and infections have been recognized as predisposing factors for oral carcinogenesis. Recently, even microbiota alterations have been associated with the development of human cancers. In particular, some specific bacterial strains have been recognized and strongly associated with oral cancer development (Capnocytophaga gingivalis, Fusobacter...
Source: Oncology Letters - March 28, 2020 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

The Effects of Selenium-Enriched Probiotics on Growth Performance, Oocysts Shedding, Intestinal Cecal Lesion Scores, Antioxidant Capacity, and mRNA Gene Expression in Chickens Infected with Eimeria tenella.
This study was carried out to investigate the effects of selenium-enriched probiotics (SP) supplementation on growth performance, oocysts shedding, intestinal lesions and antioxidant capacities, and mRNA gene expression of local Chinese yellow male chickens infected with Eimeria tenella. One-day-old 270 chickens were randomly assigned into five groups, each consisting of three replicates with 18 chickens per replicate. Chickens in the negative and positive controls (NC, PC, respectively) received basal diets only (0.11 mg Se/kg), whereas the other groups were supplied basal diets with probiotics and designated as...
Source: Biological Trace Element Research - March 28, 2020 Category: Biology Authors: Mengistu BM, Bitsue HK, Huang K Tags: Biol Trace Elem Res Source Type: research

Assessment of safety aspect and probiotic potential of autochthonous Enterococcus faecium strains isolated from spontaneous fermented sausage.
CONCLUSION: The results indicated that E. faecium isolates from spontaneously fermented sausage showed a potential for further investigation and possible application as probiotics. PMID: 32222865 [PubMed - as supplied by publisher] (Source: Biotechnology Letters)
Source: Biotechnology Letters - March 28, 2020 Category: Biotechnology Authors: Žugić Petrović TD, Ilić PD, Grujović MŽ, Mladenović KG, Kocić-Tanackov SD, Čomić LR Tags: Biotechnol Lett Source Type: research

Non-pathogenic Escherichia coli biofilms: effects of growth conditions and surface properties on structure and curli gene expression.
Abstract Biofilm formation is a harmful phenomenon in many areas, such as in industry and clinically, but offers advantages in the field of biocatalysis for the generation of robust biocatalytic platforms. In this work, we optimised growth conditions for the production of Escherichia coli biofilms by three strains (PHL644, a K-12 derivative with enhanced expression of the adhesin curli; the commercially-used strain BL21; and the probiotic Nissle 1917) on a variety of surfaces (plastics, stainless steel and PTFE). E. coli PHL644 and PTFE were chosen as optimal strain and substratum, respectively, and conditions (in...
Source: Archives of Microbiology - March 28, 2020 Category: Microbiology Authors: Leech J, Golub S, Allan W, Simmons MJH, Overton TW Tags: Arch Microbiol Source Type: research

Influences of different drying methods on the structural characteristics and prebiotic activity of polysaccharides from bamboo shoot (Chimonobambusa quadrangularis) residues.
Abstract In the present study, in order to assess the influences of drying methods on the chemical structures, in vitro digestibility and prebiotic potential of polysaccharides extracted from Chimonobambusa quadrangularis shoot (CPSs), four drying methods, including hot air-, vacuum-, freeze-, and spray-drying, were utilized to dry CPSs. Results revealed that the physicochemical characteristics and prebiotic activity of CPSs varied by different drying methods. In comparison with the other drying methods, freeze-dried CPSs had higher uronic acid content (9.58%), lower medium-high molecular weight (117.63 kDa), sm...
Source: International Journal of Biological Macromolecules - March 28, 2020 Category: Biochemistry Authors: Chen GJ, Hong QY, Ji N, Wu WN, Ma LZ Tags: Int J Biol Macromol Source Type: research

Guidelines for best practice in placebo-controlled experimental studies on probiotics in rodent animal models
Beneficial Microbes, Ahead of Print. (Source: Beneficial Microbes)
Source: Beneficial Microbes - March 27, 2020 Category: Gastroenterology Authors: E.M. Myles M.E. O ’Leary I.D. Romkey A. Piano V. de Carvalho T.A. Tompkins T.S. Perrot Source Type: research

Immune modulatory capacity of probiotic lactic acid bacteria and applications in vaccine development
Beneficial Microbes, Ahead of Print. (Source: Beneficial Microbes)
Source: Beneficial Microbes - March 27, 2020 Category: Gastroenterology Authors: N. Mojgani Y. Shahali M. Dadar Source Type: research

Probiotic Mixture of Lactobacillus plantarum Strains Improves Lipid Metabolism and Gut Microbiota Structure in High Fat Diet-Fed Mice
The global prevalence of obesity is rising year by year, which has become a public health problem worldwide. In recent years, animal studies and clinical studies have shown that some lactic acid bacteria possess an anti-obesity effect. In our previous study, mixed lactobacilli (Lactobacillus plantarum KLDS1.0344 and Lactobacillus plantarum KLDS1.0386) exhibited anti-obesity effects in vivo by significantly reducing body weight gain, Lee’s index and body fat rate; however, its underlying mechanisms of action remain unclear. Therefore, the present study aims to explore the possible mechanisms for the inhibitory effect ...
Source: Frontiers in Microbiology - March 26, 2020 Category: Microbiology Source Type: research

Dietary Clostridium butyricum supplementation modifies significantly the liver transcriptomic profile in weaned piglets
AbstractThe addition of probiotics in swine nutrition is known to positively influence both health and growth. The current study investigates differences in the hepatic transcriptome profiles between weaned piglets supplemented withClostridium butyricum (C.  butyricum) and control animals that received no probiotic. The liver is an important metabolic organ that plays a critical role in oxidizing triglycerides for energy production, lipid synthesis and degradation, as well as immune regulation in animals. RNA ‐Seq analysis was carried out on total RNA harvested from the liver of piglets fed with (n = 3) or...
Source: Journal of Animal Physiology and Animal Nutrition - March 25, 2020 Category: Zoology Authors: Jiayun Qiao, Haihua Li, Yupeng Li Tags: ORIGINAL ARTICLE Source Type: research

Retail refrigerated probiotic foods and their association with evidence of health benefits
Beneficial Microbes, Ahead of Print. (Source: Beneficial Microbes)
Source: Beneficial Microbes - March 25, 2020 Category: Gastroenterology Authors: Z. Dailey M.E. Sanders D. Merenstein Source Type: research

Molecules, Vol. 25, Pages 1490: Bifidobacterium animalis subsp. lactis A6 Alleviates Obesity Associated with Promoting Mitochondrial Biogenesis and Function of Adipose Tissue in Mice
o Zhang Li Probiotics are widely known for their health benefits. Mitochondrial dysfunction is related to obesity. The aim of this study was to illuminate whether Bifidobacterium animalis subsp. lactis A6 (BAA6) could improve obesity due to increased mitochondrial biogenesis and function of adipose tissues. Four-week-old male C57BL/6 mice were fed with a high-fat diet (HFD) for 17 weeks. For the final eight weeks, the HFD group was divided into three groups including HFD, HFD with BAA6 (HFD + BAA6 group), and HFD with Akkermansia muciniphila (AKK) (HFD + AKK group as positive control). The composition of the micr...
Source: Molecules - March 25, 2020 Category: Chemistry Authors: Huo Lu Wang Wang Chen Guo Zhang Li Tags: Article Source Type: research

Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome.
Conclusions: The novel probiotics have beneficial effects on defecation in a murine model of IBS. Human studies confirming the efficacy are warranted. PMID: 32209802 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK Tags: Korean J Gastroenterol Source Type: research

Effect of supra-nutritional selenium-enriched probiotics on hematobiochemical, hormonal, and  Doppler hemodynamic changes in male goats.
In this study, the influence of supra-nutritional organic selenium (Se) supplement on hematology and plasma biochemicals, including antioxidant parameters and plasma reproductive hormones, as well as blood flow characteristics in the supratesticular and common carotid arteries (STA and CCA, respectively) were investigated. For this purpose, 15 male goats were used and classified into three equal groups according to the supplementation of the basal diet (BD): negative control (NC), probiotic (Pro), and Se-probiotic (Se-Pro) groups. Blood perfusion in the STA and CCA was assessed by Doppler ultrasonography at three different...
Source: Environmental Science and Pollution Research International - March 25, 2020 Category: Environmental Health Authors: Mandour AS, Samir H, El-Beltagy MA, Abdel-Daim MM, Izumi W, Ma D, Matsuura K, Tanaka R, Watanabe G Tags: Environ Sci Pollut Res Int Source Type: research

Dietary Clostridium butyricum supplementation modifies significantly the liver transcriptomic profile in weaned piglets
AbstractThe addition of probiotics in swine nutrition is known to positively influence both health and growth. The current study investigates differences in the hepatic transcriptome profiles between weaned piglets supplemented withClostridium butyricum (C.  butyricum) and control animals that received no probiotic. The liver is an important metabolic organ that plays a critical role in oxidizing triglycerides for energy production, lipid synthesis and degradation, as well as immune regulation in animals. RNA ‐Seq analysis was carried out on total RNA harvested from the liver of piglets fed with (n = 3) or...
Source: Journal of Animal Physiology and Animal Nutrition - March 24, 2020 Category: Zoology Authors: Jiayun Qiao, Haihua Li, Yupeng Li Tags: ORIGINAL ARTICLE Source Type: research

Antioxidant and Anti-inflammatory Effect of Probiotic Lactobacillus plantarum KU15149 Derived from Korean Homemade Diced-Radish Kimchi.
Abstract Lactobacillus plantarum KU15149 was demonstrated to have probiotic behavior and functions, including antioxidant and anti-inflammatory activity. L. plantarum KU15149 obtained from homemade diced-radish kimchi and has a high survival rate under artificial gastric acid (pH 2.5, 0.3% pepsin) and bile salt (0.3% oxgall) conditions. However, L. plantarum KU15149 did not produce β-glucuronidase, which is known to be a carcinogenic enzyme with resistance to several antibiotics, such as gentamycin, kanamycin, streptomycin, tetracycline, and ciprofloxacin. L. plantarum KU15149 strongly adhered to HT-29 cells ...
Source: Journal of Microbiology and Biotechnology - March 24, 2020 Category: Biotechnology Authors: Han KJ, Lee JE, Lee NK, Paik HD Tags: J Microbiol Biotechnol Source Type: research

Probiotic properties and immune-stimulating effect of the Jeju lava seawater mineral-coated probiotics
Publication date: Available online 23 March 2020Source: LWTAuthor(s): Kyung Min Kim, Seo-Jin Yang, Du Seong Kim, Chang-Wan Lee, Ha Yeon Kim, Suyeon Lee, Ji-Whi Choi, Johann Sohn, Song Seok Shin, Seunghun Lee (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - March 23, 2020 Category: Food Science Source Type: research

Suppression of Staphylococcus aureus Superantigen-Independent Interferon Gamma Response by a Probiotic Polysaccharide [Host Response and Inflammation]
Staphylococcus aureus is a Gram-positive opportunistic pathogen that causes a variety of diseases. Bloodstream infection is the most severe, with mortality rates reaching 20 to 50%. Exopolysaccharide (EPS) from the probiotic Bacillus subtilis reduces bacterial burden and inflammation during S. aureus bloodstream infection in mice. Protection is due, in part, to hybrid macrophages that restrict S. aureus growth through reactive oxygen species and to limiting superantigen-induced T cell activation and interferon gamma (IFN-) production during infection. A decrease in IFN- production was observed within 24 h after infection, ...
Source: Infection and Immunity - March 23, 2020 Category: Infectious Diseases Authors: Paik, W., Alonzo, F., Knight, K. L. Tags: Host Response and Inflammation Source Type: research

Evaluation of probiotic carboxymethyl cellulose-sodium caseinate films and their application in extending shelf life quality of fresh trout fillets
Publication date: Available online 20 March 2020Source: LWTAuthor(s): Mahya Mozaffarzogh, Ali Misaghi, Yasser Shahbazi, Abolfazl Kamkar (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - March 22, 2020 Category: Food Science Source Type: research