Bifidobacterium longum suppresses colorectal cancer through the modulation of intestinal microbes and immune function
Colorectal cancer (CRC), one of the most common malignancies in the world, urgently requires more treatment strategies. Although there has been much research on probiotics, limited research has been done in treating cancer. The purpose of this study was to investigate the role of Bifidobacterium longum (B. longum) in the prevention and treatment of CRC. Through Cell Counting Kit-8 and Colony Formation Assays, 8 h and a B. longum count of 1 × 108 CFU/ml were chosen as the best cocultivation conditions with CRC cells. The role of B. longum in inhibiting the progression of CRC cells was verified by a series of functional and...
Source: Frontiers in Microbiology - March 22, 2024 Category: Microbiology Source Type: research
The anticancer effect of potential probiotic L. fermentum and L. plantarum in combination with 5-fluorouracil on colorectal cancer cells
In conclusion, the cell extracts of the lactobacilli strains probably can act as a potential complementary anticancer therapy. (Source: World Journal of Microbiology and Biotechnology)
Source: World Journal of Microbiology and Biotechnology - March 22, 2024 Category: Microbiology Source Type: research
Lactobacillus casei Shirota probiotic drinks reduce antibiotic associated diarrhoea in patients with spinal cord injuries who regularly consume proton pump inhibitors: a subgroup analysis of the ECLISP multicentre RCT
Spinal Cord, Published online: 22 March 2024; doi:10.1038/s41393-024-00983-wLactobacillus casei Shirota probiotic drinks reduce antibiotic associated diarrhoea in patients with spinal cord injuries who regularly consume proton pump inhibitors: a subgroup analysis of the ECLISP multicentre RCT (Source: Spinal Cord)
Source: Spinal Cord - March 22, 2024 Category: Research Authors: Samford Wong Shashivadan P. Hirani Alastair Forbes Naveen Kumar Ramaswamy Hariharan Jean O ’Driscoll Ravi Sekhar Ali Jamous Source Type: research
Diet, exercise, and supplements: what is their role in the management of the metabolic dysfunction-associated steatotic liver disease in children?
AbstractMetabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD), is the main cause of chronic liver disease in children and adolescents. Indeed, epidemiological studies have shown that MASLD affects up to 40% of children with obesity. Despite the recent approval of medications that target weight loss in adolescents that could have benefits on pediatric MASLD, lifestyle interventions, such as diet and exercise, remain the mainstay of our therapeutic approach. More specifically, studies on diet alone have focused on the possible role of carbohydrate or fa...
Source: Endocrine - March 22, 2024 Category: Endocrinology Source Type: research
