Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
The objective of the Clinical Coordinating Center application is to provide the scientific rationale and a comprehensive scientific and operational plan for the clinical trial. Clinical Coordinating Center applications are expected to describe plans for project management, participant recruitment and retention strategies, performance milestones, scientific conduct, and dissemination of results. Clinical Coordinating Center applications submitted under this NOFO will utilize a two-phase, milestone-driven, cooperative agreement (UG3/UH3) funding mechanism. In addition, an accompanying Data Coordinating Center application, su...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 2, 2024 Category: Research Source Type: funding
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
Funding Opportunity PAR-24-115 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitt...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2024 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Funding Opportunity PAR-24-116 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, tr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2024 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Funding Opportunity PAR-24-124 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 1, 2024 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Funding Opportunity PAR-20-218 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. Under this FOA, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This FOA will provide up to two years (R61 pha...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 20, 2020 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Funding Opportunity PAR-20-217 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. Under this FOA, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This FOA will provide up to 3 years support fo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 20, 2020 Category: Research Source Type: funding
Notice of Participation of the National Center for Complementary and Integrative Health (NCCIH) in PA-18-876 "Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Not Allowed)"
Notice NOT-AT-19-001 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 2, 2018 Category: Research Source Type: funding
Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Optional)
Funding Opportunity PA-18-902 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 14, 2018 Category: Research Source Type: funding
Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-18-876 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is twofold: (1) to stimulate basic and mechanistic science that facilitates the development of effective probiotics or pre-/probiotic combinations of relevance to human health and disease; and (2) determine biological outcomes for the evaluation of efficacy of pre/probiotics in appropriate test systems and animal models. This FOA encourages basic and mechanistic studies using in vitro, in vivo, ex vivo, and in silico models that focus on prebiotic/probiotic strain selectivity, interaction...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 25, 2018 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Funding Opportunity PAR-18-828 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for investigator-initiated early phase clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. Under this FOA, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This FOA will provide up to 3 years support for...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 13, 2018 Category: Research Source Type: funding
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Funding Opportunity PAR-18-829 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for investigator-initiated early phase clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. Under this FOA, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This FOA will provide up to two years (R61 phas...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 13, 2018 Category: Research Source Type: funding
NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01 Clinical Trial Required)
Funding Opportunity PAR-18-125 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites cooperative agreement applications for investigator-initiated clinical trials of natural products to treat clinical symptoms such as those associated with sleep disturbance, pain conditions, or some mental health conditions (e.g., mild to moderate depression, anxiety, and post-traumatic stress), or examine the effects of probiotics and other natural products on gut-microbiome interactions with the brain and/or immune system. All applications submitted under this FOA must be supported by suffici...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 30, 2017 Category: Research Source Type: funding
Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Optional)
Funding Opportunity PA-18-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 1, 2017 Category: Research Source Type: funding
Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01)
Funding Opportunity Number: PA-15-135 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: EducationFood and NutritionHealthIncome Security and Social ServicesCFDA Number: 93.12193.21393.27993.32193.39393.39493.39593.39693.39993.84693.84793.85993.865Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative...
Source: Grants.gov - March 10, 2015 Category: Research Tags: Education Food and Nutrition Health Income Security and Social Services Source Type: funding
Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01)
Funding Opportunity PA-15-135 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is twofold: (1) to stimulate basic and mechanistic science that facilitates the development of effective probiotics or pre-/probiotic combinations of relevance to human health and disease; and (2) determine biological outcomes for the evaluation of efficacy of pre/probiotics in appropriate test systems and animal models. This FOA encourages basic and mechanistic studies using in vitro, in vivo, ex vivo, and in silico models that focus on prebiotic/probiotic strain selectivity, interact...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 9, 2015 Category: Research Source Type: funding
