Digital Health Makes Healthcare Globalised
Consider Atlas Biomed, the company behind the at-home microbiome test: it is based in the U.K. Some 1,900 kilometers away in Italy, Dante Labs offers direct-to-consumer whole genome sequencing kits. On the other side of the Atlantic Ocean, in the U. S., is Fitbit, which ships its fitness trackers around the world. Despite being headquartered in different countries and even in different continents, patients now have access to quality digital health services wherever they are (save for some shipping restrictions). This aspect of digital health heralds one of its lesser-explored advantages: it enables healthcare to be ...
Source: The Medical Futurist - August 18, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Healthcare Design Healthcare Policy digital health Source Type: blogs

Fight Aging! Newsletter, August 17th 2020
In this study, we sought to elucidate the role of VRK-1 in regulation of adult life span in C. elegans. We found that overexpression of VRK-1::GFP (green fluorescent protein), which was detected in the nuclei of cells in multiple somatic tissues, including the intestine, increased life span. Conversely, genetic inhibition of vrk-1 decreased life span. We further showed that vrk-1 was essential for the increased life span of mitochondrial respiratory mutants. We demonstrated that VRK-1 was responsible for increasing the level of active and phosphorylated form of AMPK, thus promoting longevity. A Fisetin Variant, C...
Source: Fight Aging! - August 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing the Mechanisms of Longevity in Long-Lived Bats
Today's open access research is a good companion piece to a recent paper that investigates biochemical differences between long-lived and short-lived bats. Bats are renowned for, firstly, an exceptional resistance to classes of virus that are fatal to other mammals, allowing bat populations to act as reservoirs for potentially dangerous pathogens, and secondly for an exceptional longevity in comparison to other mammalian species of a similar size. In mammals, species longevity tends to scale up with size, with a few notable and well-studied long-lived exceptions such as naked mole-rats, humans, and some bats. In ter...
Source: Fight Aging! - August 14, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Autoimmune diseases and vitamin D
While vitamin D deficiency does not initiate the process of autoimmunity in which the body’s immune system wages an attack on an organ such as the thyroid, skin, pancreas, or joints, it plays a “permissive” role, i..e, vitamin D deficiency allows some other factor to initiate the process. For this reason, getting your vitamin D blood level into an ideal range provides great advantage in preventing autoimmunity or in helping you reverse it. The post Autoimmune diseases and vitamin D appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - July 31, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open autoimmune Inflammation undoctored vitamin D wheat belly Source Type: blogs

Micro-LEDs and Solar Panels Wirelessly Power Medical Implants
Researchers at the Gwangju Institute of Science and Technology in South Korea have developed a method to wirelessly power implanted devices using light. The technique involves a micro-LED patch to transmit light through the skin and a photovoltaic system on implanted devices that can turn this light into electricity. This technology could help researchers to develop devices that do not need batteries, avoiding the need to remove and replace them when the batteries are depleted. Implantable electronic medical devices have had a significant impact on healthcare, particularly on the long-term management of chronic conditio...
Source: Medgadget - July 8, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Cardiology Materials Medicine Neurology Neurosurgery Pain Management Source Type: blogs

Medtronic ’s MiniMed 780G with Artificial Pancreas Capabilities Cleared in EU
Medtronic won the EU CE Mark for its MiniMed 780G closed loop insulin pump that features both Medtronic’s own SmartGuard algorithm and MD-Logic, an algorithm developed by DreaMed Diabetes, a small Israeli firm. The system, indicated to be used by patients with type 1 diabetes between ages 7 and 80, automatically delivers both basal insulin and correcting boluses every five minutes, if necessary. Such close monitoring and control of blood glucose levels may help patients stay within a healthy range while reducing worry about forgetting to track every instance of food intake. Target glucose levels can be set to as ...
Source: Medgadget - June 18, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Informatics Medicine Telemedicine Source Type: blogs

Five Things You May Not Realize Can Affect Your Mental Health
Did you know diabetes affects your mental health? From depression to relationship problems or mood swings, too much or too little glucose (sugar) circulating in the blood can trigger behavior and thought patterns that may seem unrelated to how much insulin is released by your pancreas. Out of control glucose levels influence how you feel and make decisions, your beliefs and, yes, your attitude, a very necessary component of your overall care.  The U.S. Centers for Disease Control and Prevention (CDC) states less than half the number of people with diabetes who have depression get treated, which leads to worsening states o...
Source: World of Psychology - May 30, 2020 Category: Psychiatry & Psychology Authors: Jan McDaniel Tags: Mental Health and Wellness Comorbidities Diabetes Drug Interactions Nutrition Source Type: blogs

If you ’re falling apart, should you still perform the pancreas biopsy?
Many radiologists choose the specialty because they don ’t like interacting with sick people. As a highly sensitive person, I went into radiology to distance myself from patient suffering, as a means of self-protection. Radiology has allowed me to compartmentalize, sort of. It allowed me to have three healthy babies: one in residency, one at the […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 23, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/tracey-oconnell" rel="tag" > Tracey O'Connell, MD < /a > < /span > Tags: Physician Orthopedics Radiology Source Type: blogs

Weight-loss drug Belviq recalled
In February, the manufacturer of the weight-loss medication lorcaserin (Belviq, Belviq XR) voluntarily withdrew the drug from the US market at the request of the FDA. This was a result of emerging data showing that people who had taken the drug as part of a large clinical trial had an increased occurrence of cancer five years later. What were the findings about Belviq, and why did this information come to light now? Lorcaserin was approved by the FDA in 2012. As part of the approval process, the FDA reviewed a series of clinical trials that looked at its effects on weight and its safety profile, compared to a placebo. Base...
Source: Harvard Health Blog - April 9, 2020 Category: Consumer Health News Authors: Florencia Halperin, MD Tags: Diet and Weight Loss Drugs and Supplements Source Type: blogs

Bigfoot Biomedical for More Accurate Insulin Dosing: Interview with CMO Red Maxwell
Managing insulin-dependent diabetes is no easy task. Most patients manually measure blood glucose and calculate insulin dosing using traditional multiple dose injection (MDI) therapy, a burdensome process that puts them at risk for both hypo- and hyperglycemia. Bigfoot Biomedical is working on a solution to take the guesswork out of MDI. The Milpitas, CA-based company is developing the Bigfoot Unity Diabetes Management Program, an integrated system that helps patients dose their insulin more easily and accurately. The system consists of a mobile phone app plus proprietary insulin pen caps, pen needles, Abbott glucose se...
Source: Medgadget - March 26, 2020 Category: Medical Devices Authors: Cici Zhou Tags: Exclusive Medicine Source Type: blogs

Fight Aging! Newsletter, March 23rd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - March 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Failing Mitochondrial Quality Control with Age Considered in Terms of Inter-Organelle Contact Sites
The review paper here provides an interesting perspective on the interaction between mitochondria and lysosomes, looking at the mechanics of their membrane contact sites in the context of mitochondrial quality control and its age-related decline. Every cell plays host to hundreds of mitochondria, bacteria-like organelles responsible for generating adenosine triphosphate molecules to power cellular processes. Mitochondrial function declines throughout the body with age, and this appears to be largely a problem of failing quality control. The quality control processes of mitophagy identify worn and damaged mitochondria, ensu...
Source: Fight Aging! - March 20, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Mapping p16 and p21 Markers of Cellular Senescence in Humans by Tissue and Age
In that part of the research community focused on the role of cellular senescence in aging, the consensus is that the markers presently used to identify senescent cells are placeholders waiting for a better approach. They are not sufficiently universal. Senescent cells might be different enough in different tissues to require tissue specific approaches to assess their presence to a usefully exact degree. This point is illustrated by the results of a recent survey of p16 and p21 in humans by tissue type and age. That neither p16 nor p21 expressing cells increased in number with age in lung tissue strongly suggests that...
Source: Fight Aging! - March 19, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Paracentesis: The Procedure
Discussion: The Z-track method minimizes fluid leakage from the puncture site. Injecting medication into the skin using this method is important to preventing post-procedure leaking. Once a needle has entered subcutaneous tissue and muscle, it opens a track that may not reseal immediately. There are also studies suggesting that Z tracks may reduce pain during injection. We suggest using the method during your paracentesis procedure.Z tracks are used for all kinds of intramuscular injections and can be applied to other sites on the body. Pull and press the skin and tissue 2 cm caudad to the deep abdominal wall and inser...
Source: The Procedural Pause - March 3, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

5 Things That Will Dominate The 2020s For Pharma Companies
What’s worth some 1,204.8 billion USD? Well, it’s the worldwide pharmaceutical market, of course! With such a capital at stake and with the pace of technological disruption, the pharma industry is quick to adapt to the changing times. In fact, leading drug companies are re-investing as much as 20.8% of drug sales into new drug development.  We’ve analyzed the trends shaping the future of pharma before, but how can we expect to see the landscape evolve in this new decade? With leaps in A.I., patient empowerment and 3D printed drugs, here are the 5 aspects that will be the focus of pharmaceutical companies in t...
Source: The Medical Futurist - February 25, 2020 Category: Information Technology Authors: Prans Tags: Future of Pharma digital health future of medicine pharmaceutics digital health companies Source Type: blogs