An Artificial Pancreas Leader, on Her Life and Career with Type 1 Diabetes
DiabetesMine interviews Jen Block of Bigfoot Biomedical, about her own life with type 1 diabetes and work on new closed loop technology. (Source: Diabetes Mine)
Source: Diabetes Mine - April 17, 2019 Category: Endocrinology Authors: Mike Hoskins Source Type: blogs
Ten reasons to never eat wheat
How can conventional dietary advice gotten it so wrong?
Rather than eating plenty of “healthy whole grains,” people on the Wheat Belly lifestyle eat absolutely no grains and enjoy spectacular weight loss and reversal of hundreds of health conditions as a result. Unfortunately, many people view this as a “gluten-free” lifestyle which is incorrect.
Here are 10 reasons why no bagels, pretzels, or sandwiches made from wheat flour should ever cross human lips.
Gliadin-derived opioid peptides (from partial digestion to 4- and 5-amino acid long fragments) increase appetite substantially–as do related pro...
Source: Wheat Belly Blog - April 14, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle Gliadin gluten Inflammation Weight Loss Source Type: blogs
Fight Aging! Newsletter, April 1st 2019
In conclusion, long-term aerobic exercise appears to attenuate the decline in endothelial vascular function, a benefit which is maintained during chronological aging. However, currently there is not enough evidence to suggest that exercise interventions improve vascular function in previously sedentary healthy older adults.
Hijacking the Proteasome to Dispose of Unwanted Molecules in Age-Related Disease
https://www.fightaging.org/archives/2019/03/hijacking-the-proteasome-to-dispose-of-unwanted-molecules-in-age-related-disease/
Cells are equipped with a protein disposal system in the form of the proteas...
Source: Fight Aging! - March 31, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Why Does the Aging Metabolism Bias Towards Fat Accumulation and Lipid Deposition?
Irina Conboy's pithy description of what aging does to the operation of metabolism runs much as follows: "stem cells are sleeping, so damage is not regenerated. Instead you now make fibrous tissue, and deposit fat tissue to replace the damage. Then gradually over time, you just turn into this big scar and big fat blob." It is certainly the case that the older body seems to tend to hold on to lipids, create fat tissue, and put fats and other lipids into cells where they are usually not found in large amounts in youth. We might well ask why this happens. Is it the result of damage, some form of dysregulation of normal metabo...
Source: Fight Aging! - March 28, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Most Pressing Issues In Bioethics
Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where is the boundary to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal concerns are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the most pressing issues in bioethics.
Bioethicists
of the world...
Source: The Medical Futurist - March 26, 2019 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Genomics bioethical data debate DNA future gene editing genetic genetics Innovation legal longevity medical medical data moral sex sexuality technology Source Type: blogs
The Cruelty of Managed Medicare
By HANS DUVEFELT MD
Jeanette Brown had lost twenty pounds, and she was worried.
“I’m not trying,” she told me at her regular diabetes visit as I pored over her lab results. What I saw sent a chill down my spine:
A normal weight, diet controlled diabetic for many years, her glycosylated hemoglobin had jumped from 6.9 to 9.3 in three months while losing that much weight.
That is exactly what happened to my mother some years ago, before she was diagnosed with the pancreatic cancer that took her life in less than two years.
Jeanette had a normal physical exam and all her bloodwork except for the sugar num...
Source: The Health Care Blog - March 18, 2019 Category: Consumer Health News Authors: Matthew Holt Tags: Health Policy Medicare Hans Duvefelt Managed Care Source Type: blogs
Fight Aging! Newsletter, March 18th 2019
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases.
There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - March 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fewer Calories, Better Cell Performance
Calorie restriction, reducing calorie intake by 40% or so while maintaining optimal micronutrient intake, is the most reliable way to upregulate all of the cellular maintenance processes that act to improve cell and tissue function. This response to famine evolved very early on in the history of life on our planet, and near all organisms assessed by the research community have a cellular metabolism that operates more efficiently when calories intake is restricted. While everyone should consider trying calorie restriction, given the health benefits it conveys, and given that it costs nothing, it isn't the path to a sizable ...
Source: Fight Aging! - March 13, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Tea Bag Implant Protects Islet Cells While Letting Insulin Flow Out
Type 1 diabetes patients have to inject themselves with insulin to replace the inability of beta cells of pancreas to produce the hormone. To cure Type 1 diabetes will require either a way to “fix” the pancreas and prevent it from being damaged by the immune system, or some sort of implant that can generate insulin as the body requires.
Researchers at University of Arizona, working with others, including researchers at Novo Nordisk and University of Alberta, are now perfecting a new device that can generate insulin from within the body. This artificial pancreas relies on donated islet cells. Islet cell transpla...
Source: Medgadget - March 11, 2019 Category: Medical Devices Authors: Editors Tags: Genetics Materials Medicine Pediatrics Source Type: blogs
Alex Trebek reminds us to go beyond fear of pancreatic cancer
The news that beloved game show host Alex Trebek has advanced stage pancreatic cancer hit his millions of fans hard this week. His illness has elicited heartbreak and support. As a clinician who treats pancreatic cancer, I anticipated the reaction that would follow next. Fear. While it is a rare form of cancer, pancreatic cancer […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 8, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/burton-eisenberg" rel="tag" > Burton Eisenberg, MD < /a > < /span > Tags: Conditions #Instagram Oncology/Hematology Source Type: blogs
Alex Trebek diagnosed with pancreatic cancer. A brave journey begins.
The news that Alex Trebek has advanced stage IV pancreatic cancer has been met with an outpouring of support and good wishes, as would be expected for someone who has been a part of our lives for so many years. The fact is, pancreatic cancer is a difficult disease to treat effectively. That is due in no small […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 7, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/j-leonard-lichtenfeld" rel="tag" > J. Leonard Lichtenfeld, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs
Alex Trebek diagnosed with pancreatic cancer. A new journey begins.
The news that Alex Trebek has advanced stage IV pancreatic cancer has been met with an outpouring of support and good wishes, as would be expected for someone who has been a part of our lives for so many years. The fact is, pancreatic cancer is a difficult disease to treat effectively. That is due in no small […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 7, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/j-leonard-lichtenfeld" rel="tag" > J. Leonard Lichtenfeld, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs
Clearance of Senescent Cells Prevents Type 1 Diabetes in Animal Models
This result is unexpected, I have to say. Type 1 diabetes is not an age-related disease in any way; the majority of cases appear early. It is also understood to be an autoimmune condition, in which the immune system mistakenly attacks a particular tissue type or cell population. Yet researchers here show that senescent cells are a primary driver of the pathology of the condition, the death of beta cells in the pancreas and consequent severe metabolic dysfunction due to a lack of insulin. The accumulation of senescent cells is a mechanism associated with aging, not early life. This work raises many questions, such as will r...
Source: Fight Aging! - March 6, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, February 25th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - February 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Transplantation of Young Bone Marrow Improves Brain Function in Old Mice
The immune cells of the brain are somewhat different in character and function from those of the body. They have a greater portfolio of tasks beyond chasing down pathogens, clearing out waste, and assisting in regeneration. For example, the immune cells known as microglia are involved in the maintenance of synaptic connections between neurons. Interestingly, microglia are not produced in the bone marrow by stem cells or progenitor cells, so in the research here in which young bone marrow is transplanted into old mice, one can be fairly sure that any beneficial effects on microglia result from signaling differences on the p...
Source: Fight Aging! - February 21, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
