Microalgal assemblages response to water quality remediation in coastal waters of Perth, Australia
Environ Pollut. 2024 Apr 27:124017. doi: 10.1016/j.envpol.2024.124017. Online ahead of print.ABSTRACTNutrient reduction is an essential environmental policy for water quality remediation, but climate change can offset the ecological benefits of nutrient reduction and lead to the difficulty of environmental evaluation. Here, based on the records of three lipid microalgal biomarkers and stable isotopes of carbon and nitrogen in two sediment cores from the embayment of Perth, Australia, we reconstructed the microalgal biomasses (diatoms, dinoflagellates and coccolithophores) over the past century and evaluated the ecological ...
Source: Environmental Pollution - April 30, 2024 Category: Environmental Health Authors: Chongran Zhou Dongyan Liu John Keesing Ning Zhao Oscar Serrano Pere Masqu é Zineng Yuan Yonghao Jia Yujue Wang Source Type: research
Hyperkalemia Recurrence Following Medical Nutrition Therapy in Patients with Stage 3-4 Chronic Kidney Disease: The REVOLUTIONIZE I Real-World Study
CONCLUSION: Most patients with stage 3-4 CKD had hyperkalemia recurrence, and MNT alone was inadequate to prevent recurrence. These patients may require additional long-term treatment, such as novel potassium binders, to maintain normokalemia and prevent hyperkalemia recurrence following MNT. Infographic available for this article. INFOGRAPHIC.PMID:38687454 | DOI:10.1007/s12325-024-02835-8 (Source: Adv Data)
Source: Adv Data - April 30, 2024 Category: Epidemiology Authors: Christopher G Rowan Abiy Agiro K Arnold Chan Ellen Colman Katie White Pooja Desai Jamie P Dwyer Source Type: research
Protein-losing enteropathy: is it Crohn's disease?
Rev Esp Enferm Dig. 2024 Apr 30. doi: 10.17235/reed.2024.10461/2024. Online ahead of print.ABSTRACTCase of a 24-year-old woman presenting due to edema in lower extremities. The patient had had infectious mononucleosis three weeks prior and had medical history of suspicion of Crohn's disease (CD) (due to a non-specific ileocolitis in a colonoscopy/EnteroRM). No ongoing medication. Laboratory evaluation unveiled hypoproteinemia with severe hypoalbuminemia, no renal abnormalities. A PLE was assumed, with post-infectious or CD being the most likely culprits. Alternative causes were extensively excluded. A videocapsule revealed...
Source: Revista Espanola de Enfermedades Digestivas - April 30, 2024 Category: Gastroenterology Authors: Maria Jos é Temido Sandra Lopes Pedro Figueiredo Francisco Portela Source Type: research
Assembly and succession of the phyllosphere microbiome and nutrient-cycling genes during plant community development in a glacier foreland
In this study, considering core and satellite microbial taxa, we characterized the phyllosphere microbiome and functional genes in various microhabitats (i.e., leaf litter, moss and plant leaves) across the succession of a plant community in a low-altitude glacier foreland. Our findings indicate that phyllosphere microbiomes and associated ecosystem stability increase during the succession of the plant community. The abundance of core taxa increased with plant community succession and was primarily governed by deterministic processes. In contrast, satellite taxa abundance decreased during plant community succession and was...
Source: Environment International - April 30, 2024 Category: Environmental Health Authors: Jian Li Ming-Kang Jin Lijie Huang Zhan-Feng Liu Tao Wang Rui-Ying Chang Michiel Op de Beeck Hans Lambers Dafeng Hui Ke-Qing Xiao Qing-Lin Chen Jordi Sardans Josep Pe ñuelas Xiao-Ru Yang Yong-Guan Zhu Source Type: research
Real-world experience with filgotinib for rheumatoid arthritis in Germany : A retrospective chart review
CONCLUSIONS: In clinical practice in Germany, reasons for initiating filgotinib in patients with RA were related to dosing flexibility and general JAK inhibitor attributes. Filgotinib was used predominantly as monotherapy and was effective and generally well tolerated; however, longer-term data in larger, prospective cohorts are needed.PMID:38689038 | DOI:10.1007/s00393-024-01506-x (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 30, 2024 Category: Rheumatology Authors: Olaf Schultz Christoph Fiehn Christian Kneitz Nils Picker Daniel Kromer Monia Zignani Francesco De Leonardis Hans-Dieter Orzechowski Margot Gurrath Klaus Kr üger Source Type: research
Culinary Medicine Experiences for Medical Students and Residents in the U.S. and Canada: A Scoping Review
Teach Learn Med. 2024 Apr 30:1-27. doi: 10.1080/10401334.2024.2340977. Online ahead of print.ABSTRACTPHENOMENON: Despite the importance of diet in the prevention and management of many common chronic diseases, nutrition training in medicine is largely inadequate in medical school and residency. The emerging field of culinary medicine offers an experiential nutrition learning approach with the potential to address the need for improved nutrition training of physicians. Exploring this innovative nutrition training strategy, this scoping review describes the nature of culinary medicine experiences for medical students and res...
Source: Teaching and Learning in Medicine - April 30, 2024 Category: Universities & Medical Training Authors: Caitlin A Hildebrand Meghana B Patel Alyssa B Tenney Julia A Logan Khanh H Luong Miranda J Crouch Amanda E Osta Courtney DeRoo Kurt O Gilliland Timothy S Harlan Alice S Ammerman Source Type: research
Evaluating the efficacy and safety of therapeutic interventions for corneal neuropathy: A systematic review
Ocul Surf. 2024 Apr 28:S1542-0124(24)00050-8. doi: 10.1016/j.jtos.2024.04.004. Online ahead of print.ABSTRACTCorneal neuropathy involves corneal nerve damage that disrupts ocular surface integrity, negatively impacting quality-of-life from pain and impaired vision. Any ocular or systemic condition that damages the trigeminal nerve can lead to corneal neuropathy. However, the condition currently does not have standardized diagnostic criteria or treatment protocols. The primary aim of this systematic review was to evaluate the efficacy and safety of interventions for treating corneal neuropathy. Randomized controlled trials ...
Source: The Ocular Surface - April 30, 2024 Category: Opthalmology Authors: Rajni Rajan Eve Makrai Ji-Hyun Lee Sumeer Singh Holly R Chinnery Laura E Downie Source Type: research
Sleep duration is associated with appetitive traits in school-age years - results from the Generation XXI birth cohort
In conclusion, in 7 y children, sleep duration was cross-sectionally associated with lower scores on food approach (Food Responsiveness) and avoidant traits (Emotional Undereating and Food Fussiness). However, the magnitude of the associations was small and further studies are warranted.PMID:38688409 | DOI:10.1016/j.appet.2024.107384 (Source: Appetite)
Source: Appetite - April 30, 2024 Category: Nutrition Authors: Rita Pereira Alexandra Costa Sarah Warkentin Sofia Vilela Andreia Oliveira Source Type: research
Coping strategies of food insecure households with children and adolescents in Uruguay, a high-income Latin American country: A qualitative study through the lens of Bourdieu's theories of capitals and practice
Appetite. 2024 Apr 27:107383. doi: 10.1016/j.appet.2024.107383. Online ahead of print.ABSTRACTFood insecurity has been associated with negative short, medium, and long-term health consequences, which are more detrimental for children and adolescents. These effects may depend on the coping strategies developed to deal with food shortages. The present research aimed at exploring coping strategies in food insecure households with children and adolescents in Uruguay, incorporating sociological theoretical insights from Bourdieu. A qualitative approach based on individual semi-structured interviews was used. A total of 40 inter...
Source: Appetite - April 30, 2024 Category: Nutrition Authors: Ger ónimo Brunet Leandro Mach ín Gabriela Fajardo Luciana Bonilla Mar ía Costa Fernanda Gonz ález Silvia Bentancor Sof ía Verdier Alejandra Girona Mar ía Rosa Curutchet Luc ía Pochellú Adriana Cauci Gast ón Ares Source Type: research
Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: Am J Clin Nutr)
Source: Am J Clin Nutr - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research
Investigating the effects of Thymus vulgaris essential oil, Allium cepa extract, and their active compounds (thymol and quercetin) on expression profile of genes related to Alzheimer's disease in PC12 model cell
The objectives of this research were investigating the effects of these compounds on the pathogenesis and progress of Alzheimer's disease in cells modeled by formaldehyde. MTT, flow cytometry, and RT-PCR were used to investigate the toxicity, survival rate and apoptosis of the cells, and the expression level of PP2A, GSK3, NMDAR, BACE1, and APP genes, respectively. Also, the total antioxidant capacity of the modeled cells was measured. The results showed that the two compounds as well as the plants extract and essential oil were able to increase the percentage of cell survival; among them, Thymus vulgaris essential oil had...
Source: Brain Research - April 30, 2024 Category: Neurology Authors: Saba Foroughi Kahin Shahanipour Ramesh Monajemi Ali Mohammad Ahadi Source Type: research
Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multi-country analysis
CONCLUSIONS: Morphometric analysis of duodenal biopsy slides across geographies identified morphologic features of EED, specifically short villi, elongated crypts, and a smaller V:C ratio relative to NPA slides; although not as severe as in celiac slides. Morphometry did not explain other EED features, suggesting that EED histopathologic processes may be operating independently of morphology. While acknowledging the challenges with obtaining relevant tissue, these data form the basis for further assessments of the role of morphometry in EED.PMID:38685382 | DOI:10.1016/j.ajcnut.2024.04.027 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - April 30, 2024 Category: Nutrition Authors: Lubaina Ehsan David Coomes Paul Kelly Adam R Greene S Asad Ali Chola Mulenga Donna M Denno Kelley VanBuskirk Muhammad Faraz Raghib Mustafa Mahfuz Sean R Moore M Shabab Hossain Tahmeed Ahmed Peter B Sullivan Christopher A Moskaluk Sana Syed EEDBI Consortiu Source Type: research
Polysorbate 80 coated chitosan nanoparticles for delivery of α-Melanocyte Stimulating Hormone analog (NDP-MSH) to the brain reverse cognitive impairment related to neuroinflammation produced by a high-fat diet (HFD)
This study aimed to develop polysorbate 80-coated chitosan nanoparticles (PS80/CS NPs) as a delivery system for improved brain targeting of α-Melanocyte Stimulating Hormone analog (NDP-MSH). Chitosan nanoparticles loaded with NDP-MSH were surface-modified with polysorbate 80 ([NDP-MSH]-PS80/CS NP), which formed a flattened layer on their surface. Nanoparticle preparation involved ionic gelation, followed by characterization using scanning electron microscopy (SEM) for morphology, dynamic light scattering (DLS) for colloidal properties, and ATR-FTIR spectroscopy for structure. Intraperitoneal injection of FITC-PS80/CS NPs ...
Source: Neuropharmacology - April 30, 2024 Category: Drugs & Pharmacology Authors: Guadalupe Herrera Teresa Scimonelli Lasaga Mercedes Gladys Granero Ren ée Onnainty Source Type: research
Open Defecation, Livestock Ownership, and Child Nutritional Status in India
Am J Trop Med Hyg. 2024 Apr 30:tpmd230405. doi: 10.4269/ajtmh.23-0405. Online ahead of print.ABSTRACTSouth Asian children are among the most severely malnourished worldwide. One prominent hypothesis is that open defecation in the local area exposes children to human fecal pathogens that can cause diarrhea and malnutrition. Much of the existing research uses district-level measures of open defecation, which could mask important local-area variation. A second hypothesis is that animal fecal matter is a major source of exposure. This analysis tested these dual hypotheses using census data collected from 949 villages in Tamil ...
Source: Am J Trop Med Hyg - April 30, 2024 Category: Infectious Diseases Authors: Nancy Luke Yubraj Acharya Marco Faytong-Haro Di Yang Hongwei Xu Anu Mary Oommen Winsley Rose Source Type: research
The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study
CONCLUSION: These studies provide novel insights into the association between fasting and incremental GLP-1, metabolic traits of diabetes and obesity, and dietary intake and raise intriguing questions regarding the relevance of fasting GLP-1 in the pathophysiology T2D.PMID:38686701 | DOI:10.1210/clinem/dgae119 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 30, 2024 Category: Endocrinology Authors: Rebeca Eriksen Margaret C White Adem Y Dawed Isabel Garcia Perez Joram M Posma Mark Haid Sapna Sharma Cornelia Prehn Louise E Thomas Robert W Koivula Roberto Bizzotto Andrea Mari Giuseppe N Giordano Imre Pavo Jochen M Schwenk Federico De Masi Konstantinos Source Type: research
