Effects of slit lamp-delivered retinal laser photobiomodulation in a rat model of choroidal neovascularization
This study investigated whether photobiomodulation attenuates characteristic pathological features of choroidal neovascularization in a rodent model. Experimental choroidal neovascularization was induced in Brown Norway rats with laser photocoagulation. A custom-designed, slit-lamp-mounted, 670 nm laser was used to administer retinal photobiomodulation every 3 days, beginning 6 days prior to choroidal neovascularization induction and continuing until the animals were killed 14 days later. The effect of photobiomodulation on the size of choroidal neovascular membranes was determined using isolectin-B4 immunohistochemistry a...
Source: Experimental Eye Research - May 6, 2024 Category: Opthalmology Authors: Marzieh Tahmasebi Sarvestani Glyn Chidlow John P Wood Robert J Casson Source Type: research
Bacterial growth in patients with low back pain and Modic changes: protocol of a multicentre, case-control biopsy study
In this study, we minimise contamination risk, include a control group and optimise statistical power. The main aim is to compare bacterial growth between patients with and without MCs.
Methods and analysis
This multicentre, case–control study examines disc and vertebral body biopsies of patients with cLBP. Cases have MCs at the level of tissue sampling, controls do not. Previously operated patients are included as a subgroup. Tissue is sampled before antibiotic prophylaxis with separate instruments. We will apply microbiological methods and histology on biopsies, and predefine criteria for significant bacterial gro...
Source: BMJ Open - May 6, 2024 Category: General Medicine Authors: Rolfsen, M. P., Gammelsrud, K. W., Espeland, A., Braten, L. C., Mjones, S. B., Austevoll, I., Dolatowski, F. C., Arrestad, M. B., Toppe, M. K., Orlien, I. E., Holberg-Petersen, M., Fagerland, M., Zwart, J.-A., Storheim, K., Hellum, C. Tags: Open access, Surgery Source Type: research
A joint penalized spline smoothing model for the number of positive and negative COVID-19 tests
by Dries De Witte, Ariel Alonso Abad, Thomas Neyens, Geert Verbeke, Geert Molenberghs
One of the key tools to understand and reduce the spread of the SARS-CoV-2 virus is testing. The total number of tests, the number of positive tests, the number of negative tests, and the positivity rate are interconnected indicators and vary with time. To better understand the relationship betwee n these indicators, against the background of an evolving pandemic, the association between the number of positive tests and the number of negative tests is studied using a joint modeling approach. All countries in the European Union, Switzerla...
Source: PLoS One - May 6, 2024 Category: Biomedical Science Authors: Dries De Witte Source Type: research
Individual Trajectories of Specialist Substance Use Disorder and Mental Health Treatment Utilization Among Young Adults With Substance Use Problems: A Cohort Study
CONCLUSIONS: Results demonstrated significant variation in trajectories of treatment use among young adults with substance use disorder. Differences in treatment use could indicate differences in symptom severity and complexity. In this study, treatment use was associated with socioeconomic factors, sex, and age. Integrative approaches, including interagency and interdisciplinary collaboration, will often be necessary to sufficiently address the multidimensionality of substance use disorder.PMID:38704859 | DOI:10.1080/15504263.2024.2341092 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Regine Bakken J ūratė Š Benth Halvor Fauske Lars Lien Anne S Landheim Source Type: research
The development of a road safety policy index and its application in evaluating the effects of road safety policy
Accid Anal Prev. 2024 May 3;202:107612. doi: 10.1016/j.aap.2024.107612. Online ahead of print.ABSTRACTThe paper presents an exploratory study of a road safety policy index developed for Norway. The index consists of ten road safety measures for which data on their use from 1980 to 2021 are available. The ten measures were combined into an index which had an initial value of 50 in 1980 and increased to a value of 185 in 2021. To assess the application of the index in evaluating the effects of road safety policy, negative binomial regression models and multivariate time series models were developed for traffic fatalities, fa...
Source: Accident; Analysis and Prevention. - May 4, 2024 Category: Accident Prevention Authors: Rune Elvik Source Type: research
The development of a road safety policy index and its application in evaluating the effects of road safety policy
Accid Anal Prev. 2024 May 3;202:107612. doi: 10.1016/j.aap.2024.107612. Online ahead of print.ABSTRACTThe paper presents an exploratory study of a road safety policy index developed for Norway. The index consists of ten road safety measures for which data on their use from 1980 to 2021 are available. The ten measures were combined into an index which had an initial value of 50 in 1980 and increased to a value of 185 in 2021. To assess the application of the index in evaluating the effects of road safety policy, negative binomial regression models and multivariate time series models were developed for traffic fatalities, fa...
Source: Accident; Analysis and Prevention. - May 4, 2024 Category: Accident Prevention Authors: Rune Elvik Source Type: research
Treatment effect modifiers for return-to-work in patients with musculoskeletal disorders
This study included (n=514) participants with musculoskeletal disorders on sick leave for at least 50% of their contracted work hours for at least 7 consecutive weeks with the Norwegian Labour and Welfare Administration. (Source: The Journal of Pain)
Source: The Journal of Pain - May 4, 2024 Category: Materials Science Authors: Martjie Venter, Margreth Grotle, Britt Elin Øiestad, Fiona Aanesen, Alexander Tingulstad, Tarjei Rysstad, Michael C Ferraro, James H McAuley, Aidan G Cashin Tags: Original Reports Source Type: research
Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway
CONCLUSION: After removal of all amalgam restorations, both local and general health complaints were reduced. Since blinding of the treatment was not possible, specific and non-specific treatment effects cannot be separated.PMID:38699922 | DOI:10.2340/aos.v83.40260 (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - May 3, 2024 Category: Dentistry Authors: Nivedita Sinha Harald Johan Hamre Frauke Musial Erik L Werner Lars Bj örkman Source Type: research
Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway
CONCLUSION: After removal of all amalgam restorations, both local and general health complaints were reduced. Since blinding of the treatment was not possible, specific and non-specific treatment effects cannot be separated.PMID:38699922 | DOI:10.2340/aos.v83.40260 (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - May 3, 2024 Category: Dentistry Authors: Nivedita Sinha Harald Johan Hamre Frauke Musial Erik L Werner Lars Bj örkman Source Type: research
Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway
CONCLUSION: After removal of all amalgam restorations, both local and general health complaints were reduced. Since blinding of the treatment was not possible, specific and non-specific treatment effects cannot be separated.PMID:38699922 | DOI:10.2340/aos.v83.40260 (Source: Acta Odontologica Scandinavica)
Source: Acta Odontologica Scandinavica - May 3, 2024 Category: Dentistry Authors: Nivedita Sinha Harald Johan Hamre Frauke Musial Erik L Werner Lars Bj örkman Source Type: research
Vascular Registries Contributing to VASCUNET Collaborative Abdominal Aortic Aneurysm Outcome Projects: A Scoping Review
CONCLUSION: National vascular registries from nations participating in the VASCUNET collaborative AAA projects are largely comprehensive, with high case ascertainment rates and good quality data with internal quality assurance. This provides a template for new registries wishing to join the VASCUNET collaboration and a benchmark for future research.PMID:38697257 | DOI:10.1016/j.ejvs.2024.04.037 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - May 2, 2024 Category: Surgery Authors: Anna L Pouncey Lorenz Meuli Cristina Lopez-Espada Jacob Budtz-Lilly Jonathan R Boyle Christian-Alexander Behrendt Kevin Mani Arun D Pherwani VASCUNET AAA Registry Collaborators Source Type: research
Vascular Registries Contributing to VASCUNET Collaborative Abdominal Aortic Aneurysm Outcome Projects: A Scoping Review
CONCLUSION: National vascular registries from nations participating in the VASCUNET collaborative AAA projects are largely comprehensive, with high case ascertainment rates and good quality data with internal quality assurance. This provides a template for new registries wishing to join the VASCUNET collaboration and a benchmark for future research.PMID:38697257 | DOI:10.1016/j.ejvs.2024.04.037 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - May 2, 2024 Category: Surgery Authors: Anna L Pouncey Lorenz Meuli Cristina Lopez-Espada Jacob Budtz-Lilly Jonathan R Boyle Christian-Alexander Behrendt Kevin Mani Arun D Pherwani VASCUNET AAA Registry Collaborators Source Type: research
Vascular Registries Contributing to VASCUNET Collaborative Abdominal Aortic Aneurysm Outcome Projects: A Scoping Review
CONCLUSION: National vascular registries from nations participating in the VASCUNET collaborative AAA projects are largely comprehensive, with high case ascertainment rates and good quality data with internal quality assurance. This provides a template for new registries wishing to join the VASCUNET collaboration and a benchmark for future research.PMID:38697257 | DOI:10.1016/j.ejvs.2024.04.037 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - May 2, 2024 Category: Surgery Authors: Anna L Pouncey Lorenz Meuli Cristina Lopez-Espada Jacob Budtz-Lilly Jonathan R Boyle Christian-Alexander Behrendt Kevin Mani Arun D Pherwani VASCUNET AAA Registry Collaborators Source Type: research
The chiropractors ’ dilemma in caring for older patients with musculoskeletal complaints: Collaborate, integrate, coexist, or separate?
by Cecilia Bergstr öm, Iben Axén, Jonathan Field, Jan Hartvigsen, Monique van der Marck, Dave Newell, Sidney Rubinstein, Annemarie de Zoete, Margareta Persson
The world’s elderly population is growing at a rapid pace. This has led to an increase in demand on the health and welfare systems due to age-related disorders, with musculoskeletal complaints driving the need for rehabilitation services. However, there are concerns about health services’ abil ity to meet this demand. While chiropractic care is gaining recognition for its benefits in treating older adults with musculoskeletal disorders, there is limited scient...
Source: PLoS One - May 2, 2024 Category: Biomedical Science Authors: Cecilia Bergstr öm Source Type: research
Small Cell Lung Cancer in Norway: Patterns of Care by Health Region and Survival Trends
CONCLUSION: The survival for patients with SCLC remains poor. The use of diagnostic procedures, treatment modalities, and survival differed between regions, warranting investigations to further explore the reasons.PMID:38692990 | DOI:10.1016/j.cllc.2024.04.002 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Yngvar Nilssen Odd Terje Brustugun Lars Fjellbirkeland Bj ørn Henning Grønberg Per Magnus Haram Nina Helbekkmo Åslaug Helland Sissel Gyrid Freim Wahl Marianne Aanerud Steinar Solberg Source Type: research
