GRCr8: A new rat reference assembly is released!
GRCr8 (GCA_036323735.1), the latest version of the rat reference genome assembly, is now available. GRCr8 is an evolution of mRatBN7.2 (GCA_015227675.2), the Vertebrate Genomes Project-generated rat assembly that was the first reference for this species to be adopted by the GRC for stewardship. mRatBN7.2 was an assembly of a Brown Norway (BN) male rat from the same colony at the Medical College of Wisconsin that supplied the female rat used in the 2004 RGSC_v3.4 assembly (AABR00000000.3/GCF_000001895.1). While the assembly of mRatBN7.2 was a substantial improvement over prior versions (https://pubmed.ncbi.nlm.nih.gov/37214...
Source: GenomeRef - February 2, 2024 Category: Genetics & Stem Cells Source Type: blogs

An ECG with only «marginal» change
DISCUSSION: This case nicely illustrates how subtle OMI changes really can be. The Queen of Hearts AI model did not identify OMI in the initial ECG.Below is the QoH explainability for the limb leads of the ECG #2 (left part of the image) and limb leads of ECG #3 (right side of the image). The sets of six limb leads are put next to each other for comparison. I ' ve excluded the precordial leads as they didn ' t add much information in this case. You can look at each leads and compare the two ECGs. You then can appreciate the dynamic change and see what parts of the waveform the QoH identifies as ischemic findings....
Source: Dr. Smith's ECG Blog - December 15, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs

Study finds positive self-reported aspects of the ADHD experience among young women, especially related to hyperactivity and hyperfocus
– Three young Norwegian women. Source: Young and Promising show (SBS) As is true for children and adolescents, many adults experience substantial challenges related to having ADHD. These challenges often include relationship problems, educational and work challenges, difficulty adhering to long-term plans and goals, and time and money management difficulties. Given these well-documented difficulties, it is not surprising that ADHD treatment with adults has largely adopted a deficit model that emphasizes reducing the symptoms and impairments associated with the condition. While these are important treatment goals, and the...
Source: SharpBrains - November 30, 2023 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD ADHD experience ADHD-Treatment cognition cognitions cognitive cognitive-abilities cognitive-behavioral-therapy deficits impairments resilience treatment research ymptoms Source Type: blogs

Bonus Features – November 26, 2023 – 85% of healthcare orgs boosting IT spending in 2024, 70% of orgs actively considering generative AI, plus 18 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies The latest Hospital Vitals report from Syntellis and the AHA found that hospitals have seen a 28% decline in cash reserves over the last 19 months. This is due in large part to increased expenses (from 25$ for...
Source: EMR and HIPAA - November 26, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Aerin Medical Akasa American Hospital Association Artera AvaSure BrightSpring Health Services CancerIQ Carestream Health Clue CodaMetrix Da Vinci Project Derrick Sung eHealth Exchange EHR Association First Healt Source Type: blogs

Trial By Error: Norwegian Lightning Process Trial Ejects Questioning Participant
By David Tuller, DrPH The administrators of a controversial study of the Lightning Process currently being conducted in Norway have ejected a participant who expressed critical views about the biopsychosocial approach to ME, according to MELivet [MELife], Nina Steinkopf’s invaluable blog. This decision appears to be an acknowledgement that the intervention only works if you … Trial By Error: Norwegian Lightning Process Trial Ejects Questioning Participant Read More » (Source: virology blog)
Source: virology blog - October 5, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Crawley Lightning Process Nina Steinkopf norway Source Type: blogs

Very fast regular tachycardia: 2 ECGs from the same patient. What is going on?
This was written by Magnus Nossen, from Norway, with comments and additions by SmithA 50 something smoker with no previous medical hx contacted EMS due to acute onset chest pain. Upon EMS arrival the patient appeared acutely ill and complained of chest pain. An ECG was recorded immediately and is shown below. How do you interpret the ECG?ECG#1There is a regular tachycardia with a ventricular rate of about 180 bpm. Smith comment: When there is a regular wide complex tachycardia, first assess whether it is sinus or not.  At a rate of 180, this is unlikely.  The patient is unstable.  Therefore, the first s...
Source: Dr. Smith's ECG Blog - September 27, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs

Bonus Features – August 6, 2023 – 83% of hospitals are collecting SDoH data, 46% of hospitals planning to use large language models in the call center, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Research Five in six (83%) of hospitals are collecting SDoH data, according to the latest ONC Data Brief, with 74% using structured, electronic screening tools. Another 60% of hospitals are receiving SDoH data from out...
Source: EMR and HIPAA - August 6, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT ACO REACH AdvancedMD athenahealth Barracuda Cadence CareAR Carenet Health Cedar Clarify Health Cognizant Configo Health Connect Cost Plus Drugs David Bertoch David S. Wichmann Denise Ceule Dr. Mark Cohen e Source Type: blogs

Study: Self-guided internet-delivered treatment can significantly reduce ADHD symptoms among adults
Although ADHD was originally considered to be a disorder of childhood, it has been clear for years that it also impacts adults. At least 60% of children diagnosed with ADHD struggle with symptoms into adulthood and the estimated prevalence of ADHD in adults is between 4 and 5%. As with children and teens, medication treatment is extensively used to treat ADHD in adults. Although medication is a core treatment for adult ADHD, and helps many individuals, many continue to experience impairment and some experience adverse effects that preclude ongoing medication treatment. Although psychological treatments for adult ADHD — e...
Source: SharpBrains - June 7, 2023 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD Brain/ Mental Health ADHD-Treatment adult-AD/HD awareness training emotion regulation goal-setting inhibition training internet-delivered medication-treatment MyADHD planning psychoeducation psychological p Source Type: blogs

What Is Next for the Arctic Council in the Wake of Russian Rule?
Norway recently took over chairmanship of the Arctic Council from Russia under conditions never before experienced by the organization in its 27-year history. Despite the current uncertainties, there could be ways to move past the stalemate between Russia and the other council members. (Source: The RAND Blog)
Source: The RAND Blog - May 15, 2023 Category: Health Management Authors: Abbie Tingstad; Stephanie Pezard Source Type: blogs

Government Proposes To Make Bad Standards on Race and Ethnicity Worse
John F. EarlyI recently laid out the case to stop government classification of people by race and ethnicity in a CatoBlog post. Those observations were stimulated by The Office of Management and Budget (OMB) posting a notice for comment in the Federal Register with respect to a report from the Federal Interagency Technical Working Group and Race and Ethnicity Standards to revise the existing standards for collecting data by race and ethnicity. Comments are due by April 27, 2023.Ipublished a similar op ‐​ed in the Wall Street Journal, which subsequently printed a singleletter to the editor in re...
Source: Cato-at-liberty - April 18, 2023 Category: American Health Authors: John F. Early Source Type: blogs

Trial By Error: Further Thoughts on that JAMA Network Open Article and Estimates of Long Covid Prevalence
By David Tuller, DrPH *April is crowdfunding month at UC Berkeley. If you like my work, consider making a tax-deductible donation to Berkeley’s School of Public Health to support the Trial By Error project:  https://crowdfund.berkeley.edu/project/37217 Last week, I wrote two posts–here and here–about a new Norwegian study in JAMA Network Open that was essentially designed not … Trial By Error: Further Thoughts on that JAMA Network Open Article and Estimates of Long Covid Prevalence Read More » (Source: virology blog)
Source: virology blog - April 12, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized JAMA Network Open Long Covid norway Source Type: blogs

Trial By Error: What is Recovery Norway ’ s Role in the JAMA Network Open Study of Long Covid in Young People?
By David Tuller, DrPH*April is crowdfunding month at UC Berkeley. If you like my work, consider making a tax-deductible donation to Berkeley’s School of Public Health to support the Trial By Error project:  https://crowdfund.berkeley.edu/project/37217 As I wrote earlier this week, a new study of adolescents and young adults from Norway, published by JAMA Network Open, … Trial By Error: What is Recovery Norway’s Role in the JAMA Network Open Study of Long Covid in Young People? Read More » (Source: virology blog)
Source: virology blog - April 8, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized JAMA Lightning Process Long Covid Recovery Norway wyller Source Type: blogs

TikTok Is More Than “Cute Dance Videos”
Paul MatzkoA TikTok ban would shut down a  platform used by 150 million Americans. It would be the single, largest impairment of free speech in the history of the United States. By some estimates, half of all TikTok users have uploaded a video to the platform, meaning that a congressional ban would, in one fell swoop, remove speech utter ed by ~75 million Americans.This is precisely why those advocating for a  forced sale or ban of TikTok because of its ownership by the Chinese company Bytedance have a habit of belittling the content on the platform. Critics will use a photo of teenagers doing the latest viral TikTok...
Source: Cato-at-liberty - March 28, 2023 Category: American Health Authors: Paul Matzko Source Type: blogs

The northern lights aren ’ t in my eyes – Aurora borealis
Lots of lucky locals, by which I mean people a bit further north in Norfolk saw the northern lights, the Aurora Borealis, in Norfolk and elsewhere. There is a slight possibility of seeing them in Cambridgeshire although finding somewhere with little light pollution around here is a tough call, but more to the point it’s been cloudy and wet when other places have had their lightshow these last couple of nights. In recent years they have been observed from Devon and Cornwall. Aurora borealis at Vestrahorn, Southern Iceland (Credit: Simaron) So, what are the northern lights? The northern lights are a natural phenomenon ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - March 24, 2023 Category: Science Authors: David Bradley Tags: Astronomy Source Type: blogs

A man in his 40s with epigastric pain and ST Elevation
Case submitted by Magnus Nossen MD, written by Pendell MeyersA previously  healthy man in his 40s presented to the ED with epigastric abdominal pain off and on for several days. Vitals were within normal limits.It is unclear whether he had active pain at the time of the first ECG:What do you think?Here is PM Cardio ' s Queen of Hearts interpretation (AI ECG interpretation trained by Meyers, Smith, and PM Cardio team using thousands of cases and their outcomes):The output number ranges from 0 to 1, with numbers closer to zero meaning likely NOT OMI, and numbers closer to 1 meaning OMI. This result of 0.0002 is obviousl...
Source: Dr. Smith's ECG Blog - February 23, 2023 Category: Cardiology Authors: Pendell Source Type: blogs