Multi-faceted Anti-obesity Effects of N-Methyl-D-Aspartate (NMDA) Receptor Modulators: Central-Peripheral Crosstalk
AbstractHypothalamus is central to food intake and satiety. Recent data unveiled the expression of N-methyl-D-aspartate receptors (NMDAR) on hypothalamic neurons and their interaction with GABAA and serotoninergic neuronal circuits. However, the precise mechanisms governing energy homeostasis remain elusive. Notably, in females, the consumption of progesterone-containing preparations, such as hormonal replacement therapy and birth control pills, has been associated with hyperphagia and obesity —effects mediated through the hypothalamus. To elucidate this phenomenon, we employed the progesterone-induced obesity model in f...
Source: Journal of Molecular Neuroscience - January 19, 2024 Category: Neuroscience Source Type: research
Cardiogenic shock in a 28-year-old woman associated with sibutramine use
AbstractA 28-year-old woman collapsed in her home, and her companion rushed to call emergency services. Upon arrival, a physician performed CPR and endotracheal intubation, successfully restoring her voluntary heart rhythm. However, while en route to the hospital, ventricular fibrillation recurred. Despite the restoration of her voluntary rhythm through electrical defibrillation, she remained in a comatose state, which eventually led to multiple organ failures. Family members revealed that she had a 2-month history of taking diet pills. Histological examination revealed cardiomyocyte necrosis, contraction band necrosis, in...
Source: International Journal of Legal Medicine - January 10, 2024 Category: Medical Law Source Type: research
Is cognitive behavioral therapy more effective than pharmacotherapy for binge spectrum disorders? A systematic review and meta-analysis
CONCLUSIONS: Data are scarce, comparisons underpowered and, considering the inherent methodological limitations of psychotherapy trials, questions arise regarding the presumed superiority of cognitive behavioral therapy. Further research is needed.PMID:38179705 | DOI:10.1177/00048674231219593 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - January 5, 2024 Category: Psychiatry Authors: Myrto T Samara Niki Michou Andreas S Lappas Aikaterini Argyrou Elissavet Mathioudaki Dimitra Rafailia Bakaloudi Eirini Tsekitsidi Zoi A Polyzopoulou Nikos Christodoulou Georgios Papazisis Michail Chourdakis Source Type: research
Is cognitive behavioral therapy more effective than pharmacotherapy for binge spectrum disorders? A systematic review and meta-analysis
CONCLUSIONS: Data are scarce, comparisons underpowered and, considering the inherent methodological limitations of psychotherapy trials, questions arise regarding the presumed superiority of cognitive behavioral therapy. Further research is needed.PMID:38179705 | DOI:10.1177/00048674231219593 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - January 5, 2024 Category: Psychiatry Authors: Myrto T Samara Niki Michou Andreas S Lappas Aikaterini Argyrou Elissavet Mathioudaki Dimitra Rafailia Bakaloudi Eirini Tsekitsidi Zoi A Polyzopoulou Nikos Christodoulou Georgios Papazisis Michail Chourdakis Source Type: research
Is cognitive behavioral therapy more effective than pharmacotherapy for binge spectrum disorders? A systematic review and meta-analysis
CONCLUSIONS: Data are scarce, comparisons underpowered and, considering the inherent methodological limitations of psychotherapy trials, questions arise regarding the presumed superiority of cognitive behavioral therapy. Further research is needed.PMID:38179705 | DOI:10.1177/00048674231219593 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - January 5, 2024 Category: Psychiatry Authors: Myrto T Samara Niki Michou Andreas S Lappas Aikaterini Argyrou Elissavet Mathioudaki Dimitra Rafailia Bakaloudi Eirini Tsekitsidi Zoi A Polyzopoulou Nikos Christodoulou Georgios Papazisis Michail Chourdakis Source Type: research
Is cognitive behavioral therapy more effective than pharmacotherapy for binge spectrum disorders? A systematic review and meta-analysis
CONCLUSIONS: Data are scarce, comparisons underpowered and, considering the inherent methodological limitations of psychotherapy trials, questions arise regarding the presumed superiority of cognitive behavioral therapy. Further research is needed.PMID:38179705 | DOI:10.1177/00048674231219593 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - January 5, 2024 Category: Psychiatry Authors: Myrto T Samara Niki Michou Andreas S Lappas Aikaterini Argyrou Elissavet Mathioudaki Dimitra Rafailia Bakaloudi Eirini Tsekitsidi Zoi A Polyzopoulou Nikos Christodoulou Georgios Papazisis Michail Chourdakis Source Type: research
The Involvement of the Adrenergic System in Feeding and Eating Disorders. A systematic review
CONCLUSION: Adrenergic dysregulation may be involved in the pathophysiology of FED. More research is needed to comprehend underlying mechanisms and treatment implications.PMID:37691603 | DOI:10.1080/15622975.2023.2245458 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 11, 2023 Category: Psychiatry Authors: Jacopo Pruccoli Antonia Parmeggiani Duccio Maria Cordelli Marcello Lanari Source Type: research
The Involvement of the Adrenergic System in Feeding and Eating Disorders. A systematic review
CONCLUSION: Adrenergic dysregulation may be involved in the pathophysiology of FED. More research is needed to comprehend underlying mechanisms and treatment implications.PMID:37691603 | DOI:10.1080/15622975.2023.2245458 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 11, 2023 Category: Psychiatry Authors: Jacopo Pruccoli Antonia Parmeggiani Duccio Maria Cordelli Marcello Lanari Source Type: research
The Involvement of the Adrenergic System in Feeding and Eating Disorders. A systematic review
CONCLUSION: Adrenergic dysregulation may be involved in the pathophysiology of FED. More research is needed to comprehend underlying mechanisms and treatment implications.PMID:37691603 | DOI:10.1080/15622975.2023.2245458 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 11, 2023 Category: Psychiatry Authors: Jacopo Pruccoli Antonia Parmeggiani Duccio Maria Cordelli Marcello Lanari Source Type: research
Highly resistant and sensitive colorimetric immunochromatographic assay for sibutramine (SBT) illegally adulterated into diet food based on PDA/AuNP labelling
Analyst, 2023, Advance Article DOI: 10.1039/D2AN02094G, PaperYun Zhao, Sijie Huang, Mengjia Chao, Yulong Wang, Pengyan Liu, Pan Li, Xuechen Fang, Michael N. Routledge, Chifang Peng, Cunzheng Zhang Polydopamine coated AuNPs (PDA/AuNPs) with controlled shell thickness and packing density are synthesized and conjugated to mAb, which demonstrate high tolerance to salt and good stability in a wide pH range and improve the sensitivity of ICA. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - September 6, 2023 Category: Chemistry Authors: Yun Zhao Source Type: research
Treatment with Antiobesity Drugs in Weight Regain After Bariatric Surgery: a Retrospective Cohort Study
ConclusionTopiramate (alone or associated with sibutramine) and orlistat (alone or in combination) promoted significant weight loss after 2 years of use in patients submitted to bariatric surgery with weight regain.Graphical Abstract (Source: Obesity Surgery)
Source: Obesity Surgery - September 1, 2023 Category: Surgery Source Type: research
Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research
Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research
