A potential method for sex estimation of human skeletons using deep learning and three-dimensional surface scanning
AbstractDeep learning based on radiological methods has attracted considerable attention in forensic anthropology because of its superior classification capacities over human experts. However, radiological instruments are limited in their nature of high cost and immobility. Here, we integrated a deep learning algorithm and three-dimensional (3D) surface scanning technique into a portable system for pelvic sex estimation. Briefly, the images of the ventral pubis (VP), dorsal pubis (DP), and greater sciatic notch (GSN) were cropped from virtual pelvic samples reconstructed from CT scans of 1000 individuals; 80% of them were ...
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Forensic characterization and genomic diversity of Assam population viewed from 23 autosomal STRs
AbstractIn order to find out the genetic structure and characterize the forensic features of 23 autosomal STRs in the population of Assam, PowerPlex ® Fusion 6C amplification kit was employed to genotype 292 unrelated individuals from Assam, India. A total of 79 different alleles were observed across 23 autosomal STRs with the corresponding frequency of alleles, which ranges from 0.002 to 0.406. Selected 23 loci were observed useful together wi th the highest value of combined discrimination power (CPD = 1), combined exclusion power (CPE = 0.999999999914), combined paternity index (CPI&thins...
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Key genetic and forensic attributes of Uttarakhand population of India
AbstractThe present study aimed to investigate the genetic and forensic attributes of Uttarakhand population based on 20 autosomal STR loci implemented in PowerPlex ® 21 System. Results unveiled 219 alleles ranging from 6 (TH01, TPOX) to 20 (Penta E). Forensic analysis revealed locus Penta E as the most polymorphic and discriminative loci, whereas genetic analysis indicated presence of higher heterozygosity within population. Phylogenetic analysis indicated hi gher genetic affinity of Uttarakhand population with the neighbouring Himachal Pradesh population. Overall, the study indicates that the PowerPlex® 21 System...
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Expanding the Swiss autosomal marker set to 32 STRs
We present the first high-quality allele frequency dataset for loci D2S1360, D5S2500, D7S1517, and D10S2325 that will be accessible through the ENFSI reference database STRi dER. For loci D3S1744, D4S2366, D6S474, D8S1132, and D21S2055, we provide a first European STRidER dataset. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Correction to: Modeling microbial ethanol production by S. aureus, K. pneumoniae, and E. faecalis under aerobic/anaerobic conditions — applicability to laboratory cultures and real postmortem cases
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Correction to: The relevance of body mass index in forensic age assessment of living individuals: an age-adjusted linear regression analysis using multivariable fractional polynomials
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Correction to: A distant relationship? —investigation of correlations between DNA isolated from backspatter traces recovered from firearms, wound profile characteristics, and shooting distance
A Correction to this paper has been published:https://doi.org/10.1007/s00414-021-02626-8 (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

Correction to: Sharp force trauma with two katana swords: identifying the murder weapon by comparing tool marks on the skull bone
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 21, 2021 Category: Medical Law Source Type: research

A potential method for sex estimation of human skeletons using deep learning and three-dimensional surface scanning
AbstractDeep learning based on radiological methods has attracted considerable attention in forensic anthropology because of its superior classification capacities over human experts. However, radiological instruments are limited in their nature of high cost and immobility. Here, we integrated a deep learning algorithm and three-dimensional (3D) surface scanning technique into a portable system for pelvic sex estimation. Briefly, the images of the ventral pubis (VP), dorsal pubis (DP), and greater sciatic notch (GSN) were cropped from virtual pelvic samples reconstructed from CT scans of 1000 individuals; 80% of them were ...
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Key genetic and forensic attributes of Uttarakhand population of India
AbstractThe present study aimed to investigate the genetic and forensic attributes of Uttarakhand population based on 20 autosomal STR loci implemented in PowerPlex ® 21 System. Results unveiled 219 alleles ranging from 6 (TH01, TPOX) to 20 (Penta E). Forensic analysis revealed locus Penta E as the most polymorphic and discriminative loci, whereas genetic analysis indicated presence of higher heterozygosity within population. Phylogenetic analysis indicated hi gher genetic affinity of Uttarakhand population with the neighbouring Himachal Pradesh population. Overall, the study indicates that the PowerPlex® 21 System...
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Expanding the Swiss autosomal marker set to 32 STRs
We present the first high-quality allele frequency dataset for loci D2S1360, D5S2500, D7S1517, and D10S2325 that will be accessible through the ENFSI reference database STRi dER. For loci D3S1744, D4S2366, D6S474, D8S1132, and D21S2055, we provide a first European STRidER dataset. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: Abstracts
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: Modeling microbial ethanol production by S. aureus, K. pneumoniae, and E. faecalis under aerobic/anaerobic conditions — applicability to laboratory cultures and real postmortem cases
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: The relevance of body mass index in forensic age assessment of living individuals: an age-adjusted linear regression analysis using multivariable fractional polynomials
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: DNA barcoding and NMR spectroscopy-based assessment of species adulteration in the raw herbal trade of Saraca asoca (Roxb.) Willd, an important medicinal plant
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: A distant relationship? —investigation of correlations between DNA isolated from backspatter traces recovered from firearms, wound profile characteristics, and shooting distance
A Correction to this paper has been published:https://doi.org/10.1007/s00414-021-02626-8 (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

Correction to: Sharp force trauma with two katana swords: identifying the murder weapon by comparing tool marks on the skull bone
(Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 19, 2021 Category: Medical Law Source Type: research

A novel set of short microhaplotypes based on non-binary SNPs for forensic challenging samples
In this study, we developed a set of short microhaplotypes based on non-binary SNPs with molecular extent sizes no longer than 60 bases and genotyped 100 unrelated individuals from northern Han groups. Our results showed this panel has similar discrimination power to STR kits, as the combined random match probability (CMP) reached 1.396  × 10−22 and mean effective number of alleles (Ae) was 3.59. The cumulative probability of exclusion for duos (CPE-duos) was 0.999919 and the cumulative probability of exclusion for trios (CPE-trios) was 0.9999999987, suggesting this panel could be applied for fore...
Source: International Journal of Legal Medicine - October 15, 2021 Category: Medical Law Source Type: research

Evaluation of the effect of impaction on the mineralization of mandibular third molars and forensic age estimation in a sample of south Indian children
AbstractAssessment of third molar mineralization is a basic forensic odontological method available for age estimation in children and adolescents. Due to their protracted development into the late adolescence, their development has become the subject of interest and acquired great forensic importance. It is clearly evident in the literature that impaction factor has an influence on the rate of maturation of the third molars. In this regard, the present study was undertaken to test the relationship between impaction and its concomitant effect on the mineralization of the third molar and forensic age estimation. A total of ...
Source: International Journal of Legal Medicine - October 15, 2021 Category: Medical Law Source Type: research

Age estimation by evaluation of osteophytes in thoracic and lumbar vertebrae using postmortem CT images in a modern Japanese population
This study investigated a method for age estimation of modern Japanese individuals using osteophytes measured on CT images. The sample included 250 cadavers (125 males) aged 20–95 yea rs. The degree of osteophyte formation was evaluated as score O (0–5 points), and the degree of fusion of the osteophytes between the upper and lower vertebrae was evaluated as score B (0–2 points). Age estimation equations were developed using regression analyses with seven variables, determine d by scores O and B, and the equation with the smallest standard error of estimate (SEE) was obtained when the number of verte...
Source: International Journal of Legal Medicine - October 13, 2021 Category: Medical Law Source Type: research

Validation of the Applied Biosystems RapidHIT ID instrument and ACE GlobalFiler Express sample cartridge
AbstractRapid DNA platforms are fully automated systems capable of processing DNA from biological samples and interpreting the results in approximately 90  minutes with minimal human intervention. With a greater reliance on the system than on the analyst, validation data are especially needed to define the performance and limitations of commercially available Rapid DNA systems. Thus, validation studies of a Rapid DNA workflow consisting of the Applie d Biosystems RapidHIT ID Instrument and RapidLINK software with a focus on the ACE GlobalFiler Express Sample Cartridge and reference buccal swabs were performed in accor...
Source: International Journal of Legal Medicine - October 13, 2021 Category: Medical Law Source Type: research

Vibration as a pitfall in pyrosequencing analyses
AbstractSince methylation analysis has become an important tool in forensic genetics, the reliability and credibility of the method must be ensured. After a successful validation and establishment of several pyrosequencing assays using a PyroMark ® Q48 Autoprep instrument (Qiagen, Hilden, Germany), we decided to expand the method further purchasing a second instrument. But after initializing this second instrument side by side with the first, the majority of analyses failed (97 samples of 133 samples (73%)). The number of error messages inc reased rapidly and the average RFU values decreased. After purchasing two anti-...
Source: International Journal of Legal Medicine - October 12, 2021 Category: Medical Law Source Type: research

Legal age determined by a new threshold value of third molar maturity index in subjects with impacted mandibular third molars: An orthopantomographic study in south Indian adolescents
AbstractThird molars are one of the few biological markers available for age estimation in juveniles, especially for the estimation of the 18-year-age threshold. Literature has indicated that impaction has an influence on the development of third molars, which could possibly result in age misclassifications. The present study is intended to identify an alternative cut-off value of the third molar maturity index (I3M) in impacted mandibular third molars and also to evaluate its applicability in estimating the major ( ≥ 18 years)/minor (
Source: International Journal of Legal Medicine - October 11, 2021 Category: Medical Law Source Type: research

Development and validation of simultaneous identification of 26 mammalian and poultry species by a multiplex assay
AbstractA multiplex PCR assay was developed to simultaneously identify 22 mammalian species (alpaca, Asiatic black bear, Bactrian camel, brown rat, cat, cattle, common raccoon, dog, European rabbit, goat, horse, house mouse, human, Japanese badger, Japanese wild boar, masked palm civet, pig, raccoon dog, red fox, sheep, Siberian weasel, and sika deer) and four poultry species (chicken, domestic turkey, Japanese quail, and mallard), even from a biological sample containing a DNA mixture of multiple species. The assay was designed to identify species through multiplex PCR and capillary electrophoresis, with a combination of ...
Source: International Journal of Legal Medicine - October 9, 2021 Category: Medical Law Source Type: research

A safe procedure? The unusual case of a fatal airway obstruction by silicone during the production process of a tracheostomal epithesis in a 13-year-old boy
We report on a 13-year-old boy who died during this procedure because the lower airways were obstructed with cured silicone. Forensic autopsy confirmed asphyctic suffocation as cause of death. Forensic physical investigation of the tracheostomy tube and its cuff revealed no structural or functional defects. Yet, the investigation results prove that the viscous silicone must have passed the cuff. To conclude, this case report demonstrates that the production of an impression of a tracheostoma is a procedure with a potentially lethal outcome. Hence, professional guidelines, including clear safety precautions, are urgently ne...
Source: International Journal of Legal Medicine - October 7, 2021 Category: Medical Law Source Type: research

Estimation of the post-mortem interval in human bones by infrared spectroscopy
This study aimed to assess whether there is a correlation between changes in the bone mineral component and the PMI estimation. Samples of femur and humerus from 80 identified individuals with known post-mortem interval were analyzed. Infrared spectroscopy in attenuated total reflectance mode (FTIR-ATR) was applied for this analysis, several indices having been obtained from the infrared bands most representative of the bone ’s relative contents in carbonate and phosphate. Specific relationships between sex/age and PMI were attained: for larger PMIs, there was an increase in the amount of B-type carbonate (BPI), A-ty...
Source: International Journal of Legal Medicine - October 6, 2021 Category: Medical Law Source Type: research

Population data for 21 STRs for the Salvadoran population using GlobalFiler Express and GlobalFiler STR Amplification Kits
AbstractWith the advent of expanded STR (short tandem repeats) typing kits, it was necessary to determine allele frequencies and other appropriate population data parameters for El Salvador. Samples were collected from the central, east, and west regions of the country and typed for 21 forensically relevant STR loci. The data indicate that all loci are highly polymorphic, the three regions are genetically similar, and the population data are similar to those of US Hispanics. The results of this study support that the allele frequency data described herein can be used for statistical calculations for human identity testing ...
Source: International Journal of Legal Medicine - October 6, 2021 Category: Medical Law Source Type: research

Population data for 15 autosomal STR loci in Orang Asli subgroups of Peninsular Malaysia
This study reports the allele frequencies and several forensic statistical parameters for 15 autosomal STR loci for six Orang Asli subgroups. A total of 164 Orang Asli individuals representing the Semai, Che Wong, Oran g Kanaq, Lanoh, Bateq, and Kensui subgroups were recruited for this study. This STR data will enrich the existing Malaysian autosomal STR database and will be useful for kinship testing and forensic applications. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 4, 2021 Category: Medical Law Source Type: research

Tympanal bone fracture in forensic practice
AbstractA tympanal bone fracture is an uncommon complication of head trauma and is mostly associated with a mandibular or petrous bone fracture. Upon reviewing the medicolegal literature, we could not find any publications on this topic. Tympanal bone fracture may lead to chronic complications (including external auditory canal stenosis and conductive hearing loss), with an important impact in both the medical and judiciary fields (e.g., chronic disabilities with loss of income). We decided to investigate the prevalence and mechanisms of tympanal bone fractures by means of a retrospective observational study on living vict...
Source: International Journal of Legal Medicine - October 2, 2021 Category: Medical Law Source Type: research

Evaluating Mixture Solution ™— rapid and non-MCMC probabilistic mixture analysis
AbstractWe compare DNA mixture analysis via DNA ˑVIEW® Mixture Solution™ and the current combined probability of inclusion (CPI) method of the South African Police Service (SAPS). South Africa has a high incidence of property-related crimes and sexual offences and consequently a great deal of low-template (LT-DNA) forensic DNA mixture casewor k and a perpetual backlog. A range of casework and laboratory-prepared sexual assault mixtures with initial male DNA amounts varying from about 2 to 200 cells were analysed to evaluate the benefits of a continuous model program. Unfortunately CPI methods are nearly useless ...
Source: International Journal of Legal Medicine - October 1, 2021 Category: Medical Law Source Type: research

Fatal massive pulmonary thromboembolism and concomitant pulmonary trophoblastic embolism associated with exaggerated placental site reaction: a case study
In conclusion, this exhaustive post-mortem study describes a previously unreported association between exaggerated placental site reaction and pulmonary trophoblastic embolism, with fatal issue. Forensic pathologists should be aware that a large sampling of the lungs and uterus and examination of both placenta and fetus are needed to achieve this diagnosis. This case study emphasizes the need for further work elucidating pathways of trophoblast deportation. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 1, 2021 Category: Medical Law Source Type: research

Evaluating Mixture Solution ™— rapid and non-MCMC probabilistic mixture analysis
AbstractWe compare DNA mixture analysis via DNA ˑVIEW® Mixture Solution™ and the current combined probability of inclusion (CPI) method of the South African Police Service (SAPS). South Africa has a high incidence of property-related crimes and sexual offences and consequently a great deal of low-template (LT-DNA) forensic DNA mixture casewor k and a perpetual backlog. A range of casework and laboratory-prepared sexual assault mixtures with initial male DNA amounts varying from about 2 to 200 cells were analysed to evaluate the benefits of a continuous model program. Unfortunately CPI methods are nearly useless ...
Source: International Journal of Legal Medicine - October 1, 2021 Category: Medical Law Source Type: research

Fatal massive pulmonary thromboembolism and concomitant pulmonary trophoblastic embolism associated with exaggerated placental site reaction: a case study
In conclusion, this exhaustive post-mortem study describes a previously unreported association between exaggerated placental site reaction and pulmonary trophoblastic embolism, with fatal issue. Forensic pathologists should be aware that a large sampling of the lungs and uterus and examination of both placenta and fetus are needed to achieve this diagnosis. This case study emphasizes the need for further work elucidating pathways of trophoblast deportation. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - October 1, 2021 Category: Medical Law Source Type: research

Analysis of interrater reliability in age assessment of minors: how does expertise influence the evaluation?
In conclusion, the results of this study highlight that expertise does influence the reliability of the most util ized methods of age estimation of living individuals and stress the importance of proper training and practice, which could greatly increase the accuracy of age assessments. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Postmortem investigation of fatalities following vaccination with COVID-19 vaccines
AbstractThorough postmortem investigations of fatalities following vaccination with coronavirus disease 2019 (COVID-19) vaccines are of great social significance. From 11.03.2021 to 09.06.2021, postmortem investigations of 18 deceased persons who recently received a vaccination against COVID-19 were performed. Vaxzevria was vaccinated in nine, Comirnaty in five, Spikevax in three, and Janssen in one person. In all cases, full autopsies, histopathological examinations, and virological analyses for the severe acute respiratory syndrome coronavirus 2 were carried out. Depending on the case, additional laboratory tests (anaphy...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

It is all about the insects: a retrospective on 20  years of forensic entomology highlights the importance of insects in legal investigations
This study highlights the importance of insect evidence by evaluating 949 insect-associated cases, including 139 entomological reports, from 2001 to 2019 at the Institute of Legal Medicine Frankfurt/Germany. With a high number of cases in the summer months and a low number in the colder season, 78.5% of the bodies were found indoors, regardless of year or month. In more than 80% of the cases, where PMI information was available (n  = 704), the presumed PMI ranged from 1 to 21 days, a period during which entomological evidence can provide a day-specific estimate of PMImin. In cases where insects have been...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Homicidal poisoning series in a nursing home: retrospective toxicological investigations in bone marrow and hair
AbstractHomicidal poisonings remain rare and can be difficult to detect, especially in the elderly or in medical settings. In this atypical poisoning series, a young nursing assistant purposely poisoned thirteen residents of a nursing home and killed ten of them. The medications used were a mix of psychotropic medications (cyamemazine, loxapine, tiapride, risperidone, and mirtazapine), under liquid formulation, which were inducing malaise and coma. The forensic investigation included analysis of blood, urine, hair, and bone marrow and exhumations of seven corpses up to 3  years after the inhumation. Hair collected fro...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Analysis of interrater reliability in age assessment of minors: how does expertise influence the evaluation?
In conclusion, the results of this study highlight that expertise does influence the reliability of the most util ized methods of age estimation of living individuals and stress the importance of proper training and practice, which could greatly increase the accuracy of age assessments. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Postmortem investigation of fatalities following vaccination with COVID-19 vaccines
AbstractThorough postmortem investigations of fatalities following vaccination with coronavirus disease 2019 (COVID-19) vaccines are of great social significance. From 11.03.2021 to 09.06.2021, postmortem investigations of 18 deceased persons who recently received a vaccination against COVID-19 were performed. Vaxzevria was vaccinated in nine, Comirnaty in five, Spikevax in three, and Janssen in one person. In all cases, full autopsies, histopathological examinations, and virological analyses for the severe acute respiratory syndrome coronavirus 2 were carried out. Depending on the case, additional laboratory tests (anaphy...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

It is all about the insects: a retrospective on 20  years of forensic entomology highlights the importance of insects in legal investigations
This study highlights the importance of insect evidence by evaluating 949 insect-associated cases, including 139 entomological reports, from 2001 to 2019 at the Institute of Legal Medicine Frankfurt/Germany. With a high number of cases in the summer months and a low number in the colder season, 78.5% of the bodies were found indoors, regardless of year or month. In more than 80% of the cases, where PMI information was available (n  = 704), the presumed PMI ranged from 1 to 21 days, a period during which entomological evidence can provide a day-specific estimate of PMImin. In cases where insects have been...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Homicidal poisoning series in a nursing home: retrospective toxicological investigations in bone marrow and hair
AbstractHomicidal poisonings remain rare and can be difficult to detect, especially in the elderly or in medical settings. In this atypical poisoning series, a young nursing assistant purposely poisoned thirteen residents of a nursing home and killed ten of them. The medications used were a mix of psychotropic medications (cyamemazine, loxapine, tiapride, risperidone, and mirtazapine), under liquid formulation, which were inducing malaise and coma. The forensic investigation included analysis of blood, urine, hair, and bone marrow and exhumations of seven corpses up to 3  years after the inhumation. Hair collected fro...
Source: International Journal of Legal Medicine - September 30, 2021 Category: Medical Law Source Type: research

Endoplasmic reticulum stress-related secretory proteins as biomarkers of early myocardial ischemia-induced sudden cardiac deaths
AbstractEarly myocardial ischemia-induced sudden cardiac deaths (EMI-SCD) remain a great diagnostic challenge for forensic pathologists due to no gross or non-specific histological pathology. The goal of this study was to assess whether three secretory proteins, related with cellular endoplasmic reticulum stress, can be applied in forensic diagnosis of EMI-SCD. These markers included LMAN2, CAPN-1, and VCP and were compared with two clinically used markers (CK-MB and cTnI). A total of 21 EMI-SCD cases with a mean age of 53.0 ( ± 10.5) years and a mean ischemia interval of 
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Age-dependent gene expression of Calliphora vicina pupae (Diptera: Calliphoridae) at constant and fluctuating temperatures
We present an R-based statistical tool, which enables estimation of the age of the examined pupa based on the analysed gene expression data. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Thermal bone injuries: postmortem computed tomography findings in 25 cases
ConclusionThermal bone lesions have specific CT findings, different on several points from traumatic injuries. Their knowledge is essential for radiologists and forensic physicians to provide an accurate report of injury and conclusions. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Endoplasmic reticulum stress-related secretory proteins as biomarkers of early myocardial ischemia-induced sudden cardiac deaths
AbstractEarly myocardial ischemia-induced sudden cardiac deaths (EMI-SCD) remain a great diagnostic challenge for forensic pathologists due to no gross or non-specific histological pathology. The goal of this study was to assess whether three secretory proteins, related with cellular endoplasmic reticulum stress, can be applied in forensic diagnosis of EMI-SCD. These markers included LMAN2, CAPN-1, and VCP and were compared with two clinically used markers (CK-MB and cTnI). A total of 21 EMI-SCD cases with a mean age of 53.0 ( ± 10.5) years and a mean ischemia interval of 
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Age-dependent gene expression of Calliphora vicina pupae (Diptera: Calliphoridae) at constant and fluctuating temperatures
We present an R-based statistical tool, which enables estimation of the age of the examined pupa based on the analysed gene expression data. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Thermal bone injuries: postmortem computed tomography findings in 25 cases
ConclusionThermal bone lesions have specific CT findings, different on several points from traumatic injuries. Their knowledge is essential for radiologists and forensic physicians to provide an accurate report of injury and conclusions. (Source: International Journal of Legal Medicine)
Source: International Journal of Legal Medicine - September 27, 2021 Category: Medical Law Source Type: research

Estimation of the time of death by measuring the variation of lateral cerebral ventricle volume and cerebrospinal fluid radiodensity using postmortem computed tomography
AbstractUsing postmortem CT (PMCT), changes in the volume of the lateral cerebral ventricles (LCVs) and modifications of the radiodensity of cerebrospinal fluid (CSF) have been examined to identify a possible relationship between these changes and the time of death. Subsequent periodical CT scans termed “sequential scans” for ten corpses at known time of death were obtained, and a 3D segmentation of the entire LCV was carried out to measure its volume and radiodensity over time from ~ 5.5- h up to 273-h postmortem. A linear decrease of the LCV volume for all the cases was observed in the in vestig...
Source: International Journal of Legal Medicine - September 25, 2021 Category: Medical Law Source Type: research