Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
ConclusionThe articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China ’s NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The co llective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global hea...
Source: Infectious Diseases of Poverty - March 13, 2024 Category: Infectious Diseases Source Type: research

Serotype distribution and antimicrobial resistance of pediatric Streptococcus pneumoniae isolated from inpatients and outpatients at Beijing Children's Hospital
CONCLUSIONS: Pneumococcal vaccine-related serotypes are prevalent among both inpatients and outpatients, especially among inpatients, who exhibit more severe antibiotic resistance. Therefore, universal immunization with PCV13 would decrease the hospitalization rate due to S. pneumoniae and the antibiotic resistance rate of S. pneumoniae.PMID:38471654 | DOI:10.1016/j.bjid.2024.103734 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - March 12, 2024 Category: Infectious Diseases Authors: Shuang Lyu Wei Shi Fang Dong Bao Ping Xu Gang Liu Quan Wang Kai Hu Yao Yong Hong Yang Source Type: research

Serotype distribution and antimicrobial resistance of pediatric Streptococcus pneumoniae isolated from inpatients and outpatients at Beijing Children's Hospital
CONCLUSIONS: Pneumococcal vaccine-related serotypes are prevalent among both inpatients and outpatients, especially among inpatients, who exhibit more severe antibiotic resistance. Therefore, universal immunization with PCV13 would decrease the hospitalization rate due to S. pneumoniae and the antibiotic resistance rate of S. pneumoniae.PMID:38471654 | DOI:10.1016/j.bjid.2024.103734 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - March 12, 2024 Category: Infectious Diseases Authors: Shuang Lyu Wei Shi Fang Dong Bao Ping Xu Gang Liu Quan Wang Kai Hu Yao Yong Hong Yang Source Type: research

A National Advisory Committee on Immunization (NACI) update on invasive meningococcal disease (IMD) epidemiology and program-relevant considerations for preventing IMD in individuals at high risk of exposure
Can Commun Dis Rep. 2023 Sep 1;49(9):358-367. doi: 10.14745/ccdr.v49i09a01. eCollection 2023 Sep 1.ABSTRACTFollowing recent outbreaks of invasive meningococcal disease (IMD) in Canada and updates to provincial vaccination guidelines, the National Advisory Committee on Immunization (NACI) conducted a targeted review of evidence with a focus on immunization of adolescents and young adults. NACI reviewed national and international immunization recommendations for populations at high-risk of IMD, national IMD epidemiology and program-relevant considerations. Given the varied IMD epidemiology, NACI determined that recommending ...
Source: Can Commun Dis Rep - March 11, 2024 Category: Infectious Diseases Authors: Anne Pham-Huy Joseline Zafack Courtney Primeau Oliver Baclic Marina Salvadori Shelley Deeks Source Type: research

A Pediatric Investigators Collaborative Network on Infections in Children (PICNIC) multi-centre Canadian descriptive analysis of < em > Haemophilus influenzae < /em > bacteremia in children: Emerging serotypes
CONCLUSION: In the era of efficacious conjugate Hib vaccines, NTHi, Hia and Hif have emerged as the leading causes of invasive Hi in Canadian children, with Hia being most likely to result in meningitis and complicated disease. A vaccine for all NTHi and THi would be ideal, but knowledge of the current disease burden from circulating strains will inform prioritization of vaccine targets.PMID:38463901 | PMC:PMC10919449 | DOI:10.14745/ccdr.v49i09a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 11, 2024 Category: Infectious Diseases Authors: Craig Frankel Joan Robinson Sarah Khan Mohammad Alghounaim Jane McDonald Alison Lopez Sergio Fanella John Gunawan Jacqueline Wong Jeannette Comeau Jennifer Bowes Robert Slinger Angela Kalia Ashley Roberts Kirk Leifso Marina Ulanova Michelle Barton Source Type: research

A National Advisory Committee on Immunization (NACI) update on invasive meningococcal disease (IMD) epidemiology and program-relevant considerations for preventing IMD in individuals at high risk of exposure
Can Commun Dis Rep. 2023 Sep 1;49(9):358-367. doi: 10.14745/ccdr.v49i09a01. eCollection 2023 Sep 1.ABSTRACTFollowing recent outbreaks of invasive meningococcal disease (IMD) in Canada and updates to provincial vaccination guidelines, the National Advisory Committee on Immunization (NACI) conducted a targeted review of evidence with a focus on immunization of adolescents and young adults. NACI reviewed national and international immunization recommendations for populations at high-risk of IMD, national IMD epidemiology and program-relevant considerations. Given the varied IMD epidemiology, NACI determined that recommending ...
Source: Can Commun Dis Rep - March 11, 2024 Category: Infectious Diseases Authors: Anne Pham-Huy Joseline Zafack Courtney Primeau Oliver Baclic Marina Salvadori Shelley Deeks Source Type: research

A Pediatric Investigators Collaborative Network on Infections in Children (PICNIC) multi-centre Canadian descriptive analysis of < em > Haemophilus influenzae < /em > bacteremia in children: Emerging serotypes
CONCLUSION: In the era of efficacious conjugate Hib vaccines, NTHi, Hia and Hif have emerged as the leading causes of invasive Hi in Canadian children, with Hia being most likely to result in meningitis and complicated disease. A vaccine for all NTHi and THi would be ideal, but knowledge of the current disease burden from circulating strains will inform prioritization of vaccine targets.PMID:38463901 | PMC:PMC10919449 | DOI:10.14745/ccdr.v49i09a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 11, 2024 Category: Infectious Diseases Authors: Craig Frankel Joan Robinson Sarah Khan Mohammad Alghounaim Jane McDonald Alison Lopez Sergio Fanella John Gunawan Jacqueline Wong Jeannette Comeau Jennifer Bowes Robert Slinger Angela Kalia Ashley Roberts Kirk Leifso Marina Ulanova Michelle Barton Source Type: research

Investigation on the correlation factors of positive Streptococcus pneumoniae antibody and IgG antibody level of Streptococcus pneumoniae in the elderly over 60 years old in Shenzhen
CONCLUSION: There was a statistically significant difference in antibody positivity rates for older people with more frequent medical check-ups in Shenzhen, indicating that publicity is playing a role. The effects of age, gender, and chronic diseases on naturally acquired anti-PPS IgG differ.PMID:38458872 | DOI:10.1016/j.vaccine.2024.01.070 (Source: Vaccine)
Source: Vaccine - March 8, 2024 Category: Allergy & Immunology Authors: Lixian Su Xiaofeng Zhou Weijun Peng Jingwei Luo Qiaoxiang Lin Lizhen Liu Jian Lin Shufen Lin Kechun Zhang Hongbiao Chen Muyun Liu Source Type: research

Pneumococcal vaccination strategies in 50-year-olds to decrease racial disparities: a US societal perspective cost-effectiveness analysis
This study assesses the impact of expanding pneumococcal vaccination to all 50-year-olds to decrease racial disparities by estimating from the societal perspective, the cost-effectiveness of 20-valent pneumococcal conjugate vaccine (PCV20) and 15-valent conjugate vaccine followed by 23-valent polysaccharide vaccine (PCV15/PPSV23) for 50-year-olds. (Source: Value in Health)
Source: Value in Health - March 8, 2024 Category: International Medicine & Public Health Authors: Shoroq M. Altawalbeh, Angela R. Wateska, Mary Patricia Nowalk, Chyongchiou J. Lin, Lee H. Harrison, William Schaffner, Richard K. Zimmerman, Kenneth J. Smith Source Type: research

Introduction of the pneumococcal conjugate vaccine in humanitarian and fragile contexts: Perspectives from stakeholders in four African countries
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - March 5, 2024 Category: Allergy & Immunology Authors: Baldeep K. DhaliwalRose WeeksJasmine HuberAminata FofanaMohamed BobeAntoinette Demian MbailamenGeorge LeggeGassim CisseAnita Sheta International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Ba Source Type: research

Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific
Hum Vaccin Immunother. 2024 Dec 31;20(1):2317446. doi: 10.1080/21645515.2024.2317446. Epub 2024 Mar 4.ABSTRACTHerpes zoster (HZ) is a prevalent disease characterized by a painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, and practice (KAP) toward HZ disease and vaccination for the assessment of local factors influencing HZ vaccine perceptions in four Asian-Pacific countries/territories One-to-one qualitative interviews were conducted in 2022, among the public (people aged ≥ 50 years, adults with parents aged ≥ 50 years, zoster vaccine live-vaccinated individuals age...
Source: Pain Physician - March 4, 2024 Category: Anesthesiology Authors: Jing Chen Sumitra Shantakumar Jennifer Si Regina Gowindah Raunak Parikh Felix Chan Macy Chan Won Suk Choi Erick Huang Kuo-Chin Huang Li-Min Huang Hyungwoo Kim Choon Kit Leong Hoe-Nam Leong Yubin Seo Charles Williams Andrew Ty Wong Source Type: research

Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific
Hum Vaccin Immunother. 2024 Dec 31;20(1):2317446. doi: 10.1080/21645515.2024.2317446. Epub 2024 Mar 4.ABSTRACTHerpes zoster (HZ) is a prevalent disease characterized by a painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, and practice (KAP) toward HZ disease and vaccination for the assessment of local factors influencing HZ vaccine perceptions in four Asian-Pacific countries/territories One-to-one qualitative interviews were conducted in 2022, among the public (people aged ≥ 50 years, adults with parents aged ≥ 50 years, zoster vaccine live-vaccinated individuals age...
Source: Herpes - March 4, 2024 Category: Infectious Diseases Authors: Jing Chen Sumitra Shantakumar Jennifer Si Regina Gowindah Raunak Parikh Felix Chan Macy Chan Won Suk Choi Erick Huang Kuo-Chin Huang Li-Min Huang Hyungwoo Kim Choon Kit Leong Hoe-Nam Leong Yubin Seo Charles Williams Andrew Ty Wong Source Type: research

Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific
Hum Vaccin Immunother. 2024 Dec 31;20(1):2317446. doi: 10.1080/21645515.2024.2317446. Epub 2024 Mar 4.ABSTRACTHerpes zoster (HZ) is a prevalent disease characterized by a painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, and practice (KAP) toward HZ disease and vaccination for the assessment of local factors influencing HZ vaccine perceptions in four Asian-Pacific countries/territories One-to-one qualitative interviews were conducted in 2022, among the public (people aged ≥ 50 years, adults with parents aged ≥ 50 years, zoster vaccine live-vaccinated individuals age...
Source: Pain Physician - March 4, 2024 Category: Anesthesiology Authors: Jing Chen Sumitra Shantakumar Jennifer Si Regina Gowindah Raunak Parikh Felix Chan Macy Chan Won Suk Choi Erick Huang Kuo-Chin Huang Li-Min Huang Hyungwoo Kim Choon Kit Leong Hoe-Nam Leong Yubin Seo Charles Williams Andrew Ty Wong Source Type: research

Knowledge, attitude, and practice toward herpes zoster (HZ) and HZ vaccination: Concept elicitation findings from a multi-country study in the Asia Pacific
Hum Vaccin Immunother. 2024 Dec 31;20(1):2317446. doi: 10.1080/21645515.2024.2317446. Epub 2024 Mar 4.ABSTRACTHerpes zoster (HZ) is a prevalent disease characterized by a painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, and practice (KAP) toward HZ disease and vaccination for the assessment of local factors influencing HZ vaccine perceptions in four Asian-Pacific countries/territories One-to-one qualitative interviews were conducted in 2022, among the public (people aged ≥ 50 years, adults with parents aged ≥ 50 years, zoster vaccine live-vaccinated individuals age...
Source: Herpes - March 4, 2024 Category: Infectious Diseases Authors: Jing Chen Sumitra Shantakumar Jennifer Si Regina Gowindah Raunak Parikh Felix Chan Macy Chan Won Suk Choi Erick Huang Kuo-Chin Huang Li-Min Huang Hyungwoo Kim Choon Kit Leong Hoe-Nam Leong Yubin Seo Charles Williams Andrew Ty Wong Source Type: research

Fragments Synthesis of A. baumannii ATCC 17961 O-Antigen
Synlett DOI: 10.1055/a-2272-8163 Acinetobacter baumannii can cause many diseases including septicemia, pneumonia, meningitis, soft tissue, and urinary tract infections. Herein, we described the synthesis of one trisaccharide and two tetrasaccharide fragments derived from A. baumannii ATCC 17961 O-antigen that can be used for screening novel glyco-epitopes and for developing a synthetic carbohydrate-based vaccine against A. baumannii infection. The overall yields for the synthesis of the desired trisaccharide 1, tetrasaccharide 2, and tetrasaccharide 3 are 26.8% (8 steps), 21.6% (9 steps), and 24.5% (6 steps), respec...
Source: Synlett - March 4, 2024 Category: Chemistry Authors: Li, Xinxin Duan, Liangshen Liu, Deyong Qi, Jianying Wang, Liming Zhang, Qingju Tags: letter Source Type: research