Streptococcus pneumoniae as a colonizing agent of the Nasopharynx - Oropharynx in adults: A systematic review and meta-analysis
CONCLUSIONS: This study found a low prevalence of Spn NOC in adults. Notably, the prevalence of Spn NOC was higher in younger adults than in older adults. It is essential to highlight a significant heterogeneity among studies, which indicates there is no standardized method of Spn NOC identification.PMID:38514352 | DOI:10.1016/j.vaccine.2024.03.041 (Source: Vaccine)
Source: Vaccine - March 21, 2024 Category: Allergy & Immunology Authors: Juli án Lozada Juan Olivella G ómez Cristian C Serrano-Mayorga Andr é Emilio Viñán Garcés Valeria Enciso Lina Mendez-Castillo Alejandro Acosta-Gonz ález Ingrid G Bustos Yuli V Fuentes Elsa D Ib áñez-Prada Ana M Crispin Mar ía C Delgado-Cañavera Source Type: research
Streptococcus pneumoniae as a colonizing agent of the Nasopharynx - Oropharynx in adults: A systematic review and meta-analysis
CONCLUSIONS: This study found a low prevalence of Spn NOC in adults. Notably, the prevalence of Spn NOC was higher in younger adults than in older adults. It is essential to highlight a significant heterogeneity among studies, which indicates there is no standardized method of Spn NOC identification.PMID:38514352 | DOI:10.1016/j.vaccine.2024.03.041 (Source: Vaccine)
Source: Vaccine - March 21, 2024 Category: Allergy & Immunology Authors: Juli án Lozada Juan Olivella G ómez Cristian C Serrano-Mayorga Andr é Emilio Viñán Garcés Valeria Enciso Lina Mendez-Castillo Alejandro Acosta-Gonz ález Ingrid G Bustos Yuli V Fuentes Elsa D Ib áñez-Prada Ana M Crispin Mar ía C Delgado-Cañavera Source Type: research
Is it time to incorporate viral testing results within clinical practice guidelines for febrile infants?
The prevalence of bacteraemia and bacterial meningitis (commonly referred to as invasive bacterial infections or IBIs) among febrile infants informs ED clinician management decisions about the need for testing, treatment or hospitalisation. Using increasingly sophisticated risk stratification technologies, the management of these infants has evolved over time. Concurrently, the prevalence of IBI has decreased, largely due to vaccination and maternal antibiotic prophylaxis. The role of viral testing in medical decision-making for febrile infants is not clearly established. Prior work has suggested that febrile infants with ...
Source: Emergency Medicine Journal - March 21, 2024 Category: Emergency Medicine Authors: Money, N., Ramgopal, S. Tags: Commentary Source Type: research
Humoral and cellular immune responses induced by serogroup W135 meningococcal conjugate and polysaccharide vaccines
Vaccine. 2024 Mar 19:S0264-410X(24)00326-8. doi: 10.1016/j.vaccine.2024.03.039. Online ahead of print.ABSTRACTInvestigating the mechanisms by which W135 meningococcal conjugate (PSW135-TT) activates adaptive immune responses in mice can provide a comprehensive understanding of the immune mechanisms of bacterial polysaccharide conjugate vaccines. We compared B-cell and T-cell immune responses immunized with W135 meningococcal capsular polysaccharides (PSW135), tetanus toxoid (TT) and PSW135-TT in mice. The results showed that PSW135-TT could induce higher PSW135-specific and TT-specific IgG antibodies with a significant enh...
Source: Vaccine - March 20, 2024 Category: Allergy & Immunology Authors: Yahui Cheng Rong Shen Fanglei Liu Yanting Li Jing Wang Yali Hou Yueping Liu Haifei Zhou Fengping Hou Yunjin Wang Xiongxiong Li Ruijie Qiao Shuquan Luo Source Type: research
Evaluation of a catch-up strategy for the vaccination in patients with hepatitis C virus
Rev Esp Enferm Dig. 2024 Mar 19. doi: 10.17235/reed.2024.10386/2024. Online ahead of print.ABSTRACTVaccination in patients with advanced chronic liver disease (ACLD) is an essential part of their comprehensive healthcare. These individuals may have impaired phagocytic function and diminished production of opsonizing antibodies, resulting in increased susceptibility to bacterial infections, particularly pneumococcal pneumonia. Similarly, there is an increased risk of fulminant hepatitis due to hepatitis A and B viruses. The Ministry of Health updated specific vaccination recommendations for this group in 2018.PMID:38501772 ...
Source: Revista Espanola de Enfermedades Digestivas - March 19, 2024 Category: Gastroenterology Authors: Mar ía Fernández-Prada Andrea Fraga-P érez Paula Cienfuegos-Gonz ález Mar ía José Zapico-Baragaño Jos é Miguel Brea-Corral Adri án Huergo-Fernández Source Type: research
A phase 3, single-arm, open-label study to evaluate the safety, tolerability, and immunogenicity of a 15-valent pneumococcal conjugate vaccine, V114, in a 3+1 regimen in healthy infants in South Korea (PNEU-PED-KOR)
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - March 18, 2024 Category: Allergy & Immunology Authors: Alvino MaestriSu Eun ParkFiona FernandesZhongyi “Lucy” LiYae-Jean KimYun-Kyung KimJin LeeJi Young ParkDong Hyun KimGyongSeon YangHyunjung LimJin Oh KimRobert LupinacciTina M. SterlingMarissa WilckAlejandra Esteves-JaramilloNatalie Banniettisa MRL, Mer Source Type: research
Clinical Characteristics, Etiology, and Outcomes of Hypothermia in Well-appearing Children Referred to the Emergency Department
CONCLUSIONS: There is a low incidence of SBI in well-appearing children presenting to the PED with hypothermia and a benign course and outcome in those older than 3 months.PMID:38493326 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - March 17, 2024 Category: General Medicine Authors: Lea Ohana Sarna Dina Qaraen Saloni Mevaseret Avital Naama Pines Itai Gross Giora Wieser Saar Hashvya Source Type: research
